hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08614.1
Complex Portal: CPX-22427
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NCBP1 | Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit) | 5 | UniProt NCBI |
| SRSF12 | Serine/arginine-rich splicing factor 12 (35 kDa SR repressor protein) (SRrp35) (Splicing factor, arginine/serine-rich 13B) (Splicing factor, arginine/serine-rich 19) | 5 | UniProt NCBI |
| CLK2 | Dual specificity protein kinase CLK2 (EC 2.7.12.1) (CDC-like kinase 2) | 5 | UniProt NCBI |
| LUC7L2 | Putative RNA-binding protein Luc7-like 2 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP411 | 0.0186440023495 | 0.5 | NCBP1 CLK2 | mRNA processing |
| GO:0008380 | 0.0193524071449 | 1.0 | NCBP1 LUC7L2 SRSF12 CLK2 | RNA splicing |
| GO:0000245 | 0.0200762118412 | 0.75 | NCBP1 SRSF12 LUC7L2 | spliceosomal complex assembly |
| CORUM:775 | 0.049938562206 | 0.25 | NCBP1 | CBC complex (cap binding complex) |
| CORUM:1172 | 0.049938562206 | 0.25 | NCBP1 | CBC complex (cap binding complex) |
| CORUM:1190 | 0.049938562206 | 0.25 | NCBP1 | NCBP-NIP1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SRSF12 | LUC7L2 | 0.993 | 0.574 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt boldt_WMM |
| SRSF12 | CLK2 | 0.987 | 0.084 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt_WMM | |
| CLK2 | LUC7L2 | 0.977 | 0.12 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 boldt_WMM |
| NCBP1 | CLK2 | 0.954 | 0.102 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| NCBP1 | LUC7L2 | 0.767 | 0.374 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM treiber_WMM | |
| NCBP1 | SRSF12 | 0.692 | 0.17 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
Related Complexes