hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08634.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SLC39A10 | Zinc transporter ZIP10 (Solute carrier family 39 member 10) (Zrt- and Irt-like protein 10) (ZIP-10) | 5 | UniProt NCBI |
| SLC39A6 | Zinc transporter ZIP6 (Estrogen-regulated protein LIV-1) (Solute carrier family 39 member 6) (Zrt- and Irt-like protein 6) (ZIP-6) | 5 | UniProt NCBI |
| GPAT3 | Glycerol-3-phosphate acyltransferase 3 (GPAT-3) (EC 2.3.1.15) (1-acyl-sn-glycerol-3-phosphate O-acyltransferase 10) (AGPAT 10) (1-acyl-sn-glycerol-3-phosphate O-acyltransferase 9) (1-AGP acyltransferase 9) (1-AGPAT 9) (EC 2.3.1.51) (Acyl-CoA:glycerol-3-phosphate acyltransferase 3) (hGPAT3) (Lung cancer metastasis-associated protein 1) (Lysophosphatidic acid acyltransferase theta) (LPAAT-theta) (MAG-1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-442380 | 0.00024538606603 | 0.666666666667 | SLC39A6 SLC39A10 | Zinc influx into cells by the SLC39 gene family |
| WP:WP3529 | 0.000397139561296 | 0.666666666667 | SLC39A6 SLC39A10 | Zinc homeostasis |
| REAC:R-HSA-435354 | 0.000531572756485 | 0.666666666667 | SLC39A6 SLC39A10 | Zinc transporters |
| REAC:R-HSA-425410 | 0.00104246243986 | 0.666666666667 | SLC39A6 SLC39A10 | Metal ion SLC transporters |
| HPA:0320842 | 0.00226183881683 | 1.0 | SLC39A6 SLC39A10 GPAT3 | nasopharynx; basal cells[>=Medium] |
| HPA:0211092 | 0.00337898221093 | 1.0 | SLC39A6 SLC39A10 GPAT3 | fallopian tube; non-ciliated cells[>=Medium] |
| HPA:0210852 | 0.00421688947149 | 1.0 | SLC39A6 SLC39A10 GPAT3 | fallopian tube; ciliated cells (cell body)[>=Medium] |
| HPA:0320841 | 0.00423889063395 | 1.0 | SLC39A6 SLC39A10 GPAT3 | nasopharynx; basal cells[>=Low] |
| WP:WP2884 | 0.00700579973273 | 0.666666666667 | SLC39A6 SLC39A10 | NRF2 pathway |
| HPA:0211091 | 0.00712356679546 | 1.0 | SLC39A6 SLC39A10 GPAT3 | fallopian tube; non-ciliated cells[>=Low] |
| REAC:R-HSA-425366 | 0.00937397262456 | 0.666666666667 | SLC39A6 SLC39A10 | Transport of bile salts and organic acids, metal ions and amine compounds |
| HPA:0060852 | 0.0101525993711 | 1.0 | SLC39A6 SLC39A10 GPAT3 | bronchus; ciliated cells (cell body)[>=Medium] |
| HPA:0320852 | 0.0107970230792 | 1.0 | SLC39A6 SLC39A10 GPAT3 | nasopharynx; ciliated cells (cell body)[>=Medium] |
| HPA:0210851 | 0.0138403406022 | 1.0 | SLC39A6 SLC39A10 GPAT3 | fallopian tube; ciliated cells (cell body)[>=Low] |
| HPA:0320873 | 0.0163771345036 | 0.666666666667 | SLC39A6 GPAT3 | nasopharynx; ciliated cells (ciliary rootlets)[High] |
| HPA:0211093 | 0.0206240738009 | 0.666666666667 | SLC39A6 SLC39A10 | fallopian tube; non-ciliated cells[High] |
| HPA:0320851 | 0.021281217262 | 1.0 | SLC39A6 SLC39A10 GPAT3 | nasopharynx; ciliated cells (cell body)[>=Low] |
| KEGG:05012 | 0.0212975456297 | 0.666666666667 | SLC39A6 SLC39A10 | Parkinson disease |
| HPA:0060851 | 0.0243942396884 | 1.0 | SLC39A6 SLC39A10 GPAT3 | bronchus; ciliated cells (cell body)[>=Low] |
| HPA:0210853 | 0.0305730371719 | 0.666666666667 | GPAT3 SLC39A10 | fallopian tube; ciliated cells (cell body)[High] |
| WP:WP2882 | 0.0351361093338 | 0.666666666667 | SLC39A6 SLC39A10 | Nuclear receptors meta pathway |
| GO:0071578 | 0.0393180950424 | 0.666666666667 | SLC39A6 SLC39A10 | zinc ion import across plasma membrane |
| KEGG:05010 | 0.0433146801558 | 0.666666666667 | SLC39A6 SLC39A10 | Alzheimer disease |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| GPAT3 | SLC39A6 | 0.995 | 0.074 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| SLC39A6 | SLC39A10 | 0.987 | 0.412 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| GPAT3 | SLC39A10 | 0.986 | 0.098 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| SLC39A10 | huMAP3_08634.1 huMAP3_09592.1 |
| SLC39A6 | huMAP3_03893.1 huMAP3_08634.1 huMAP3_09592.1 |
| GPAT3 | huMAP3_02539.1 huMAP3_06247.1 huMAP3_06791.1 huMAP3_08634.1 |