hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_08641.1

Confidence: High

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Genename	Protein Name	Uniprot Annotation Score	Links
B2M	Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]	5	UniProt NCBI
CDCA2	Cell division cycle-associated protein 2 (Recruits PP1 onto mitotic chromatin at anaphase protein) (Repo-Man)	5	UniProt NCBI
KPNA3	Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3) (SRP1-gamma)	5	UniProt NCBI
KPNA4	Importin subunit alpha-3 (Importin alpha Q1) (Qip1) (Karyopherin subunit alpha-4)	5	UniProt NCBI
KPNB1	Importin subunit beta-1 (Importin-90) (Karyopherin subunit beta-1) (Nuclear factor p97) (Pore targeting complex 97 kDa subunit) (PTAC97)	5	UniProt NCBI
NEMP1	Nuclear envelope integral membrane protein 1	5	UniProt NCBI
NUP214	Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN)	5	UniProt NCBI
NUSAP1	Nucleolar and spindle-associated protein 1 (NuSAP)	5	UniProt NCBI
POM121	Nuclear envelope pore membrane protein POM 121 (Nuclear envelope pore membrane protein POM 121A) (Nucleoporin Nup121) (Pore membrane protein of 121 kDa)	5	UniProt NCBI
RAN	GTP-binding nuclear protein Ran (EC 3.6.5.-) (Androgen receptor-associated protein 24) (GTPase Ran) (Ras-like protein TC4) (Ras-related nuclear protein)	5	UniProt NCBI

Showing 1 to 10 of 19 entries

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Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0005643	4.43339738863e-19	0.666666666667	RANGAP1 RAN KPNB1 KPNA4 UBE2I POM121 SUMO1 RANBP1 RGPD8 KPNA3 RANBP2 NUP214	nuclear pore
KEGG:03013	1.7632715156e-18	0.611111111111	RANGAP1 RAN KPNB1 KPNA4 POM121 SUMO1 UBE2I SUMO2 KPNA3 RANBP2 NUP214	Nucleocytoplasmic transport
REAC:R-HSA-177243	4.68405015184e-15	0.444444444444	RANGAP1 RAN KPNB1 RCC1 POM121 NUP214 RANBP2 RANBP1	Interactions of Rev with host cellular proteins
REAC:R-HSA-9615933	1.19127265355e-13	0.388888888889	RANGAP1 RAN KPNB1 UBE2I RCC1 POM121 SUMO1	Postmitotic nuclear pore complex (NPC) reformation
GO:0005635	2.72848355067e-13	0.722222222222	RANGAP1 RAN KPNB1 KPNA4 UBE2I POM121 SUMO1 RANBP1 RGPD8 NEMP1 KPNA3 RANBP2 NUP214	nuclear envelope
REAC:R-HSA-165054	1.15241197107e-12	0.388888888889	RANGAP1 RAN RANBP2 RCC1 POM121 RANBP1 NUP214	Rev-mediated nuclear export of HIV RNA
REAC:R-HSA-162909	2.57212140756e-12	0.5	RANGAP1 RAN KPNB1 RCC1 POM121 NUP214 B2M RANBP2 RANBP1	Host Interactions of HIV factors
REAC:R-HSA-4615885	9.17615104548e-12	0.388888888889	RANBP2 SUMO2 UBE2I POM121 SUMO1 RANGAP1 NUP214	SUMOylation of DNA replication proteins
REAC:R-HSA-9824446	1.40220937287e-11	0.722222222222	B2M RANGAP1 RAN KPNB1 KPNA4 RCC1 UBE2I POM121 SUMO1 RANBP1 KPNA3 RANBP2 NUP214	Viral Infection Pathways
GO:0051169	2.93753104585e-11	0.611111111111	RANGAP1 RAN KPNB1 KPNA4 POM121 SUMO1 UBE2I RGPD8 KPNA3 RANBP2 NUP214	nuclear transport

Showing 1 to 10 of 136 entries

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Protein 1	Protein 2	Score	ProteomeHD
RAN	RANGAP1	1.0	0.242
UBE2I	SUMO1	1.0	0.234
UBE2I	RCC1	1.0	0.07
UBE2I	RANGAP1	1.0	0.202
RCC1	RANGAP1	1.0	0.254
RCC1	RANBP2	1.0	0.238
RANGAP1	RGPD5	1.0	0.14
RANBP1	RCC1	1.0	0.136
KPNB1	RCC1	1.0	0.258
RAN	RCC1	1.0	0.16

Showing 1 to 10 of 170 entries

Related Complexes

Genename	Complexes
RGPD5	huMAP3_05030.1 huMAP3_05712.1 huMAP3_07331.1 huMAP3_08641.1 huMAP3_09825.1 huMAP3_10000.1 huMAP3_12581.1
NUSAP1	huMAP3_01999.1 huMAP3_02813.1 huMAP3_06494.1 huMAP3_07331.1 huMAP3_07763.1 huMAP3_08641.1 huMAP3_09597.1 huMAP3_10000.1 huMAP3_12581.1
POM121	huMAP3_08226.1 huMAP3_08641.1 huMAP3_09825.1 huMAP3_12581.1
SUMO1	huMAP3_05712.1 huMAP3_07331.1 huMAP3_08226.1 huMAP3_08641.1 huMAP3_09825.1 huMAP3_10000.1 huMAP3_12581.1
KPNB1	huMAP3_00976.1 huMAP3_07479.1 huMAP3_08226.1 huMAP3_08641.1 huMAP3_09825.1 huMAP3_10000.1 huMAP3_12581.1
RANGAP1	huMAP3_02264.1 huMAP3_06494.1 huMAP3_07331.1 huMAP3_07828.1 huMAP3_08641.1 huMAP3_09825.1 huMAP3_10000.1 huMAP3_12581.1
CDCA2	huMAP3_08226.1 huMAP3_08641.1 huMAP3_09825.1 huMAP3_10000.1 huMAP3_12581.1
KPNA4	huMAP3_03376.1 huMAP3_07479.1 huMAP3_08226.1 huMAP3_08641.1 huMAP3_09825.1 huMAP3_10000.1 huMAP3_12581.1 huMAP3_13201.1
NUP214	huMAP3_00209.1 huMAP3_05948.1 huMAP3_06369.1 huMAP3_08641.1 huMAP3_09220.1 huMAP3_10000.1 huMAP3_12581.1
RAN	huMAP3_01999.1 huMAP3_06494.1 huMAP3_07331.1 huMAP3_07763.1 huMAP3_08641.1 huMAP3_09597.1 huMAP3_10000.1 huMAP3_12581.1 huMAP3_15098.1
RANBP1	huMAP3_01999.1 huMAP3_03516.1 huMAP3_07032.1 huMAP3_07331.1 huMAP3_08226.1 huMAP3_08641.1 huMAP3_09825.1 huMAP3_10000.1 huMAP3_12581.1
RCC1	huMAP3_02264.1 huMAP3_06494.1 huMAP3_07331.1 huMAP3_07828.1 huMAP3_08641.1 huMAP3_09597.1 huMAP3_10000.1 huMAP3_12581.1
SUMO2	huMAP3_00864.1 huMAP3_01999.1 huMAP3_02554.1 huMAP3_05860.1 huMAP3_06494.1 huMAP3_07331.1 huMAP3_07649.1 huMAP3_07958.1 huMAP3_08641.1 huMAP3_10000.1 huMAP3_12375.1 huMAP3_12581.1
RANBP2	huMAP3_05030.1 huMAP3_05712.1 huMAP3_08641.1 huMAP3_09825.1 huMAP3_10000.1 huMAP3_12581.1
RGPD8	huMAP3_08641.1 huMAP3_09825.1 huMAP3_10000.1 huMAP3_12581.1
KPNA3	huMAP3_00976.1 huMAP3_07479.1 huMAP3_08226.1 huMAP3_08641.1 huMAP3_09825.1 huMAP3_10000.1 huMAP3_12581.1
UBE2I	huMAP3_02057.1 huMAP3_02554.1 huMAP3_06494.1 huMAP3_07331.1 huMAP3_07649.1 huMAP3_08641.1 huMAP3_10000.1 huMAP3_12581.1
NEMP1	huMAP3_07331.1 huMAP3_07828.1 huMAP3_08641.1 huMAP3_09825.1 huMAP3_10000.1 huMAP3_12581.1
B2M	huMAP3_01999.1 huMAP3_06494.1 huMAP3_07331.1 huMAP3_08226.1 huMAP3_08363.1 huMAP3_08641.1 huMAP3_09825.1 huMAP3_10000.1 huMAP3_12581.1 huMAP3_13569.1