hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08646.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TNRC6B | Trinucleotide repeat-containing gene 6B protein | 5 | UniProt NCBI |
| TNRC6A | Trinucleotide repeat-containing gene 6A protein (CAG repeat protein 26) (EMSY interactor protein) (GW182 autoantigen) (Protein GW1) (Glycine-tryptophan protein of 182 kDa) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-426496 | 3.58839967947e-05 | 1.0 | TNRC6B TNRC6A | Post-transcriptional silencing by small RNAs |
| REAC:R-HSA-9768778 | 4.78453290596e-05 | 1.0 | TNRC6B TNRC6A | Regulation of NPAS4 mRNA translation |
| REAC:R-HSA-8948700 | 4.78453290596e-05 | 1.0 | TNRC6B TNRC6A | Competing endogenous RNAs (ceRNAs) regulate PTEN translation |
| REAC:R-HSA-8943723 | 6.15154230766e-05 | 1.0 | TNRC6B TNRC6A | Regulation of PTEN mRNA translation |
| REAC:R-HSA-9768759 | 7.68942788458e-05 | 1.0 | TNRC6B TNRC6A | Regulation of NPAS4 gene expression |
| REAC:R-HSA-8934593 | 0.00023239159829 | 1.0 | TNRC6B TNRC6A | Regulation of RUNX1 Expression and Activity |
| REAC:R-HSA-9634815 | 0.000645911942305 | 1.0 | TNRC6B TNRC6A | Transcriptional Regulation by NPAS4 |
| REAC:R-HSA-9022692 | 0.000693757271364 | 1.0 | TNRC6B TNRC6A | Regulation of MECP2 expression and activity |
| REAC:R-HSA-9029569 | 0.00079457421474 | 1.0 | TNRC6B TNRC6A | NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux |
| REAC:R-HSA-2559585 | 0.000902226205124 | 1.0 | TNRC6B TNRC6A | Oncogene Induced Senescence |
| REAC:R-HSA-8853884 | 0.00113803532692 | 1.0 | TNRC6B TNRC6A | Transcriptional Regulation by VENTX |
| REAC:R-HSA-9024446 | 0.00126619245833 | 1.0 | TNRC6B TNRC6A | NR1H2 and NR1H3-mediated signaling |
| REAC:R-HSA-8986944 | 0.00235467369443 | 1.0 | TNRC6B TNRC6A | Transcriptional Regulation by MECP2 |
| REAC:R-HSA-4086398 | 0.00235467369443 | 1.0 | TNRC6B TNRC6A | Ca2+ pathway |
| REAC:R-HSA-1912408 | 0.00486997099357 | 1.0 | TNRC6B TNRC6A | Pre-NOTCH Transcription and Translation |
| REAC:R-HSA-5628897 | 0.00526469495831 | 1.0 | TNRC6B TNRC6A | TP53 Regulates Metabolic Genes |
| REAC:R-HSA-8936459 | 0.00539968713673 | 1.0 | TNRC6B TNRC6A | RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function |
| REAC:R-HSA-5687128 | 0.0055363880769 | 1.0 | TNRC6B TNRC6A | MAPK6/MAPK4 signaling |
| REAC:R-HSA-1912422 | 0.00715287669441 | 1.0 | TNRC6B TNRC6A | Pre-NOTCH Expression and Processing |
| REAC:R-HSA-2559580 | 0.00969038789632 | 1.0 | TNRC6B TNRC6A | Oxidative Stress Induced Senescence |
| REAC:R-HSA-211000 | 0.0117955823749 | 1.0 | TNRC6B TNRC6A | Gene Silencing by RNA |
| REAC:R-HSA-9018519 | 0.0136718027788 | 1.0 | TNRC6B TNRC6A | Estrogen-dependent gene expression |
| REAC:R-HSA-6807070 | 0.015455750048 | 1.0 | TNRC6B TNRC6A | PTEN Regulation |
| REAC:R-HSA-3858494 | 0.0156864328845 | 1.0 | TNRC6B TNRC6A | Beta-catenin independent WNT signaling |
| REAC:R-HSA-2559583 | 0.0260158976762 | 1.0 | TNRC6B TNRC6A | Cellular Senescence |
| REAC:R-HSA-8939211 | 0.0290831250212 | 1.0 | TNRC6B TNRC6A | ESR-mediated signaling |
| GO:0060213 | 0.0309012475255 | 1.0 | TNRC6B TNRC6A | positive regulation of nuclear-transcribed mRNA poly(A) tail shortening |
| REAC:R-HSA-157118 | 0.0353816208396 | 1.0 | TNRC6B TNRC6A | Signaling by NOTCH |
| GO:0060211 | 0.0365196561665 | 1.0 | TNRC6B TNRC6A | regulation of nuclear-transcribed mRNA poly(A) tail shortening |
| REAC:R-HSA-8878171 | 0.0378576166184 | 1.0 | TNRC6B TNRC6A | Transcriptional regulation by RUNX1 |
| REAC:R-HSA-1257604 | 0.0450002407423 | 1.0 | TNRC6B TNRC6A | PIP3 activates AKT signaling |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TNRC6B | TNRC6A | 0.998 | 0.208 | hein_WMM youn () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes