hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08650.1
Complex Portal: CPX-13187
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CYP8B1 | 7-alpha-hydroxycholest-4-en-3-one 12-alpha-hydroxylase (EC 1.14.14.139) (7-alpha-hydroxy-4-cholesten-3-one 12-alpha-hydroxylase) (CYPVIIIB1) (Cytochrome P450 8B1) (Sterol 12-alpha-hydroxylase) | 5 | UniProt NCBI |
| TACSTD2 | Tumor-associated calcium signal transducer 2 (Cell surface glycoprotein Trop-2) (Membrane component chromosome 1 surface marker 1) (Pancreatic carcinoma marker protein GA733-1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00120 | 0.0142523225448 | 0.5 | CYP8B1 | Primary bile acid biosynthesis |
| REAC:R-HSA-211994 | 0.0249718442457 | 0.5 | CYP8B1 | Sterols are 12-hydroxylated by CYP8B1 |
| HP:0010637 | 0.0499436884913 | 0.5 | TACSTD2 | Conjunctival amyloidosis |
| HP:0034804 | 0.0499436884913 | 0.5 | TACSTD2 | Corneal foreign body sensation |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| CYP8B1 | TACSTD2 | 0.99 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| CYP8B1 | huMAP3_03964.1 huMAP3_08650.1 huMAP3_11434.1 huMAP3_14095.1 |
| TACSTD2 | huMAP3_03964.1 huMAP3_08650.1 huMAP3_14095.1 |