hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08662.1
Complex Portal: CPX-20824
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NARS2 | Asparaginyl-tRNA synthetase (AsnRS) (NARS2) (EC 6.1.1.22) (Asparagine--tRNA ligase, mitochondrial) | 5 | UniProt NCBI |
| MMUT | Methylmalonyl-CoA mutase, mitochondrial (MCM) (EC 5.4.99.2) (Methylmalonyl-CoA isomerase) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0001944 | 0.00948362772432 | 1.0 | NARS2 MMUT | Dehydration |
| REAC:R-HSA-3359475 | 0.0249718442457 | 0.5 | MMUT | Defective MMAA causes MMA, cblA type |
| REAC:R-HSA-3359478 | 0.0249718442457 | 0.5 | MMUT | Defective MUT causes MMAM |
| REAC:R-HSA-9759774 | 0.0249718442457 | 0.5 | MMUT | Diseases of mitochondrial beta oxidation |
| REAC:R-HSA-9759785 | 0.0249718442457 | 0.5 | MMUT | Diseases of propionyl-CoA catabolism |
| CORUM:6861 | 0.0249718442457 | 0.5 | MMUT | MMAA-MUT complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| NARS2 | MMUT | 0.975 | 0.15 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| NARS2 | huMAP3_05734.1 huMAP3_08662.1 huMAP3_10525.1 huMAP3_13468.1 |
| MMUT | huMAP3_08662.1 huMAP3_09650.1 huMAP3_10387.1 huMAP3_10525.1 huMAP3_13468.1 |