hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08673.1
Complex Portal: CPX-13002
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CHCHD4 | Mitochondrial intermembrane space import and assembly protein 40 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 4) | 5 | UniProt NCBI |
| GFER | FAD-linked sulfhydryl oxidase ALR (EC 1.8.3.2) (Augmenter of liver regeneration) (hERV1) (Hepatopoietin) | 5 | UniProt NCBI |
| AK2 | Adenylate kinase 2, mitochondrial (AK 2) (EC 2.7.4.3) (ATP-AMP transphosphorylase 2) (ATP:AMP phosphotransferase) (Adenylate monophosphate kinase) [Cleaved into: Adenylate kinase 2, mitochondrial, N-terminally processed] | 5 | UniProt NCBI |
| TOR1AIP1 | Torsin-1A-interacting protein 1 (Lamin-associated protein 1B) (LAP1B) | 5 | UniProt NCBI |
| AIFM1 | Apoptosis-inducing factor 1, mitochondrial (EC 1.6.99.-) (Programmed cell death protein 8) | 5 | UniProt NCBI |
| TXN | Thioredoxin (Trx) (ATL-derived factor) (ADF) (Surface-associated sulphydryl protein) (SASP) (allergen Hom s Trx) | 5 | UniProt NCBI |
| CAMTA1 | Calmodulin-binding transcription activator 1 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0045041 | 0.0210651876021 | 0.333333333333 | CHCHD4 AIFM1 | protein import into mitochondrial intermembrane space |
| HP:0003287 | 0.0252851538442 | 0.5 | GFER AK2 AIFM1 | Abnormality of mitochondrial metabolism |
| HP:0012103 | 0.0371191829266 | 0.5 | GFER AK2 AIFM1 | Abnormality of the mitochondrion |
| REAC:R-HSA-1268020 | 0.0452196184553 | 0.333333333333 | GFER CHCHD4 | Mitochondrial protein import |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TXN | CHCHD4 | 0.999 | 0.044 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 boldt_WMM WMM_only | |
| AIFM1 | AK2 | 0.999 | 0.47 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt hein () bioplex3_HCT116 fraction boldt_WMM | |
| AIFM1 | TOR1AIP1 | 0.999 | 0.166 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 | |
| CHCHD4 | TOR1AIP1 | 0.999 | 0.028 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () bioplex3_HCT116 | |
| AIFM1 | CHCHD4 | 0.998 | 0.476 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () bioplex3_HCT116 boldt_WMM | |
| CAMTA1 | CHCHD4 | 0.998 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| AIFM1 | GFER | 0.995 | 0.214 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| CHCHD4 | AK2 | 0.993 | 0.332 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM WMM_only | |
| CAMTA1 | AIFM1 | 0.992 | bioplex3_WMM bioplex3_HCT116 boldt_WMM WMM_only | ||
| CHCHD4 | GFER | 0.986 | 0.072 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| TXN | TOR1AIP1 | 0.985 | 0.17 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () bioplex3_HCT116 gupta_WMM fraction | |
| AIFM1 | TXN | 0.977 | 0.182 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM fraction boldt_WMM | |
| AK2 | TOR1AIP1 | 0.901 | 0.142 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM | |
| CAMTA1 | TOR1AIP1 | 0.83 | bioplex3_WMM WMM_only | ||
| CAMTA1 | TXN | 0.674 | bioplex3_WMM gupta_WMM WMM_only | ||
| CAMTA1 | AK2 | 0.614 | bioplex3_WMM WMM_only | ||
| CAMTA1 | GFER | 0.381 | bioplex3_WMM WMM_only | ||
| GFER | AK2 | 0.24 | 0.174 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction | |
| GFER | TOR1AIP1 | 0.127 | 0.07 | bioplex_WMM bioplex3_WMM WMM_only | |
| TXN | GFER | 0.03 | 0.082 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 fraction | |
| TXN | AK2 | 0.005 | 0.18 | bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
Related Complexes