hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_08675.1

Confidence: High

Genename	Protein Name	Uniprot Annotation Score	Links
PRPF40A	Pre-mRNA-processing factor 40 homolog A (Fas ligand-associated factor 1) (Formin-binding protein 11) (Formin-binding protein 3) (Huntingtin yeast partner A) (Huntingtin-interacting protein 10) (HIP-10) (Huntingtin-interacting protein A) (Renal carcinoma antigen NY-REN-6)	5	UniProt NCBI
PUF60	Poly(U)-binding-splicing factor PUF60 (60 kDa poly(U)-binding-splicing factor) (FUSE-binding protein-interacting repressor) (FBP-interacting repressor) (Ro-binding protein 1) (RoBP1) (Siah-binding protein 1) (Siah-BP1)	5	UniProt NCBI
ARGLU1	Arginine and glutamate-rich protein 1	4	UniProt NCBI
RBM25	RNA-binding protein 25 (Arg/Glu/Asp-rich protein of 120 kDa) (RED120) (Protein S164) (RNA-binding motif protein 25) (RNA-binding region-containing protein 7)	5	UniProt NCBI
SRRM2	Serine/arginine repetitive matrix protein 2 (300 kDa nuclear matrix antigen) (Serine/arginine-rich splicing factor-related nuclear matrix protein of 300 kDa) (SR-related nuclear matrix protein of 300 kDa) (Ser/Arg-related nuclear matrix protein of 300 kDa) (Splicing coactivator subunit SRm300) (Tax-responsive enhancer element-binding protein 803) (TaxREB803)	5	UniProt NCBI
SRSF11	Serine/arginine-rich splicing factor 11 (Arginine-rich 54 kDa nuclear protein) (p54) (Splicing factor, arginine/serine-rich 11)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:351	4.8736012294e-08	0.833333333333	SRSF11 PUF60 PRPF40A SRRM2 RBM25	Spliceosome
REAC:R-HSA-72163	5.10720654207e-07	0.833333333333	SRSF11 PUF60 PRPF40A SRRM2 RBM25	mRNA Splicing - Major Pathway
REAC:R-HSA-72172	6.06851470168e-07	0.833333333333	SRSF11 PUF60 PRPF40A SRRM2 RBM25	mRNA Splicing
REAC:R-HSA-72203	2.42636100074e-06	0.833333333333	SRSF11 PUF60 PRPF40A SRRM2 RBM25	Processing of Capped Intron-Containing Pre-mRNA
REAC:R-HSA-8953854	0.000234756919958	0.833333333333	SRSF11 PUF60 PRPF40A SRRM2 RBM25	Metabolism of RNA
KEGG:03040	0.000620541886073	0.5	PUF60 PRPF40A RBM25	Spliceosome
HPA:0301361	0.000881431512216	0.833333333333	SRSF11 PUF60 ARGLU1 SRRM2 RBM25	lung; alveolar cells type I[>=Low]
GO:0006397	0.0018087286159	0.833333333333	SRSF11 PUF60 PRPF40A SRRM2 RBM25	mRNA processing
HPA:0570782	0.00260266673604	0.833333333333	SRSF11 PUF60 ARGLU1 SRRM2 RBM25	testis; preleptotene spermatocytes[>=Medium]
HPA:0090192	0.00262114844898	1.0	PUF60 PRPF40A SRSF11 RBM25 ARGLU1 SRRM2	cerebellum; cells in molecular layer[>=Medium]
GO:0008380	0.00281759779491	0.833333333333	SRSF11 PUF60 PRPF40A SRRM2 RBM25	RNA splicing
HPA:0300202	0.0041652825202	0.666666666667	SRSF11 ARGLU1 SRRM2 RBM25	lung; endothelial cells[>=Medium]
HPA:0301371	0.00488744878147	0.833333333333	SRSF11 PUF60 ARGLU1 SRRM2 RBM25	lung; alveolar cells type II[>=Low]
HPA:0310432	0.00717300994582	1.0	PUF60 PRPF40A SRSF11 RBM25 ARGLU1 SRRM2	lymph node; germinal center cells[>=Medium]
HPA:0570792	0.00728091434471	0.833333333333	SRSF11 PUF60 ARGLU1 SRRM2 RBM25	testis; round or early spermatids[>=Medium]
HPA:0570781	0.00845401774594	0.833333333333	SRSF11 PUF60 ARGLU1 SRRM2 RBM25	testis; preleptotene spermatocytes[>=Low]
HPA:0570733	0.00866327607872	0.833333333333	SRSF11 PUF60 PRPF40A SRRM2 ARGLU1	testis; Leydig cells[High]
HPA:0300201	0.0093857194677	0.666666666667	SRSF11 ARGLU1 SRRM2 RBM25	lung; endothelial cells[>=Low]
HPA:0351182	0.0125583632269	1.0	PUF60 PRPF40A SRSF11 RBM25 ARGLU1 SRRM2	pancreas; pancreatic endocrine cells[>=Medium]
HPA:0570763	0.0130614859161	0.666666666667	PUF60 ARGLU1 SRSF11 SRRM2	testis; pachytene spermatocytes[High]
HPA:0301362	0.0136991639124	0.666666666667	SRSF11 ARGLU1 SRRM2 RBM25	lung; alveolar cells type I[>=Medium]
HPA:0350473	0.0137848177277	0.833333333333	SRRM2 SRSF11 PRPF40A RBM25 ARGLU1	pancreas; exocrine glandular cells[High]
HPA:0050092	0.0158607015262	1.0	PUF60 PRPF40A SRSF11 RBM25 ARGLU1 SRRM2	breast; myoepithelial cells[>=Medium]
HPA:0570791	0.0193965540142	0.833333333333	SRSF11 PUF60 ARGLU1 SRRM2 RBM25	testis; round or early spermatids[>=Low]
GO:0016071	0.0223509276715	0.833333333333	SRSF11 PUF60 PRPF40A SRRM2 RBM25	mRNA metabolic process
HPA:0340461	0.022484133991	1.0	PUF60 PRPF40A SRSF11 RBM25 ARGLU1 SRRM2	ovary; ovarian stroma cells[>=Low]
HPA:0620222	0.0240997991459	1.0	PUF60 PRPF40A SRSF11 RBM25 ARGLU1 SRRM2	vagina; squamous epithelial cells[>=Medium]
HPA:0570761	0.025352309659	0.833333333333	SRSF11 PUF60 ARGLU1 SRRM2 RBM25	testis; pachytene spermatocytes[>=Low]
HPA:0160251	0.0253947209828	1.0	PUF60 PRPF40A SRSF11 RBM25 ARGLU1 SRRM2	endometrium 1; cells in endometrial stroma[>=Low]
HPA:0250121	0.025436102929	1.0	PUF60 PRPF40A SRSF11 RBM25 ARGLU1 SRRM2	hippocampus; glial cells[>=Low]
HPA:0010012	0.0255999995903	0.833333333333	SRSF11 PUF60 ARGLU1 SRRM2 RBM25	adipose tissue; adipocytes[>=Medium]
HPA:0600432	0.0256021931208	1.0	PUF60 PRPF40A SRSF11 RBM25 ARGLU1 SRRM2	tonsil; germinal center cells[>=Medium]
HPA:0080132	0.0256021931208	1.0	PUF60 PRPF40A SRSF11 RBM25 ARGLU1 SRRM2	caudate; neuronal cells[>=Medium]
HPA:0090162	0.0260213768635	1.0	PUF60 PRPF40A SRSF11 RBM25 ARGLU1 SRRM2	cerebellum; Purkinje cells[>=Medium]
HPA:0160252	0.0269318614697	0.833333333333	SRSF11 PUF60 ARGLU1 SRRM2 RBM25	endometrium 1; cells in endometrial stroma[>=Medium]
HPA:0500651	0.0304891194196	1.0	PUF60 PRPF40A SRSF11 RBM25 ARGLU1 SRRM2	soft tissue 1; fibroblasts[>=Low]
HPA:0080133	0.030604492749	0.666666666667	SRSF11 PRPF40A SRRM2 ARGLU1	caudate; neuronal cells[High]
HPA:0100203	0.0317600025572	0.5	SRSF11 ARGLU1 RBM25	cerebral cortex; endothelial cells[High]
HPA:0620223	0.0332648218364	0.666666666667	SRSF11 PRPF40A SRRM2 ARGLU1	vagina; squamous epithelial cells[High]
HPA:0241102	0.035034386841	1.0	PUF60 PRPF40A SRSF11 RBM25 ARGLU1 SRRM2	heart muscle; cardiomyocytes[>=Medium]
HPA:0241103	0.0353034489875	0.666666666667	SRSF11 PRPF40A SRRM2 ARGLU1	heart muscle; cardiomyocytes[High]
HPA:0530721	0.0362409368932	1.0	PUF60 PRPF40A SRSF11 RBM25 ARGLU1 SRRM2	spleen; cells in white pulp[>=Low]
HPA:0330222	0.0368007038962	1.0	PUF60 PRPF40A SRSF11 RBM25 ARGLU1 SRRM2	oral mucosa; squamous epithelial cells[>=Medium]
HPA:0570812	0.0387978353921	0.833333333333	SRSF11 PUF60 ARGLU1 SRRM2 RBM25	testis; spermatogonia cells[>=Medium]
HPA:0360052	0.0400703067036	1.0	PUF60 PRPF40A SRSF11 RBM25 ARGLU1 SRRM2	parathyroid gland; glandular cells[>=Medium]
HPA:0540053	0.0412728490261	0.833333333333	SRRM2 SRSF11 PRPF40A RBM25 ARGLU1	stomach 1; glandular cells[High]
HPA:0090191	0.041419319273	1.0	PUF60 PRPF40A SRSF11 RBM25 ARGLU1 SRRM2	cerebellum; cells in molecular layer[>=Low]
HPA:0100202	0.0419105921912	0.833333333333	SRSF11 PUF60 ARGLU1 SRRM2 RBM25	cerebral cortex; endothelial cells[>=Medium]
HPA:0570801	0.0424633789485	0.833333333333	SRSF11 PUF60 ARGLU1 SRRM2 RBM25	testis; sertoli cells[>=Low]
HPA:0090181	0.044692740938	1.0	PUF60 PRPF40A SRSF11 RBM25 ARGLU1 SRRM2	cerebellum; cells in granular layer[>=Low]
HPA:0080121	0.0461018600179	1.0	PUF60 PRPF40A SRSF11 RBM25 ARGLU1 SRRM2	caudate; glial cells[>=Low]

Edges

Protein 1	Protein 2	Score	ProteomeHD	Evidence
RBM25	PRPF40A	1.0		hein_WMM bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM
PUF60	SRSF11	1.0		bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction
SRRM2	ARGLU1	0.997	0.078	bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction
SRRM2	PRPF40A	0.996		bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM
PUF60	SRRM2	0.993	0.66	bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction
RBM25	SRRM2	0.984	0.52	bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM
PUF60	ARGLU1	0.98	0.152	bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction treiber_WMM
PUF60	PRPF40A	0.968		bioplex3_HEK293 bioplex () bioplex_WMM Guru bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction treiber_WMM
PUF60	RBM25	0.963	0.694	bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM youn_WMM gupta_WMM fraction treiber_WMM
RBM25	SRSF11	0.963		bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM youn_WMM gupta_WMM fraction
SRSF11	ARGLU1	0.958		bioplex_WMM Guru bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM fraction
SRSF11	SRRM2	0.957		bioplex3_HEK293 bioplex_WMM Guru bioplex3_WMM youn_WMM gupta_WMM fraction
SRSF11	PRPF40A	0.779		bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
RBM25	ARGLU1	0.235	0.358	bioplex_WMM bioplex3_WMM youn_WMM WMM_only
PRPF40A	ARGLU1	0.092		bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only

Related Complexes

Genename	Complexes
PRPF40A	huMAP3_05499.1 huMAP3_05748.1 huMAP3_06487.1 huMAP3_07124.1 huMAP3_07659.1 huMAP3_08675.1 huMAP3_08947.1 huMAP3_09607.1 huMAP3_09888.1 huMAP3_09943.1 huMAP3_10010.1 huMAP3_10250.1 huMAP3_11073.1 huMAP3_12815.1 huMAP3_13743.1
PUF60	huMAP3_00347.1 huMAP3_05316.1 huMAP3_05421.1 huMAP3_06487.1 huMAP3_07096.1 huMAP3_08265.1 huMAP3_08305.1 huMAP3_08675.1 huMAP3_08947.1 huMAP3_09450.1 huMAP3_09621.1 huMAP3_09943.1 huMAP3_10010.1 huMAP3_10250.1 huMAP3_11073.1 huMAP3_11453.1 huMAP3_12815.1 huMAP3_13567.1 huMAP3_13743.1 huMAP3_15022.1 huMAP3_15349.1
ARGLU1	huMAP3_06487.1 huMAP3_07659.1 huMAP3_07967.1 huMAP3_08467.1 huMAP3_08675.1 huMAP3_09438.1 huMAP3_09621.1 huMAP3_09888.1 huMAP3_09943.1 huMAP3_10010.1 huMAP3_10250.1 huMAP3_11073.1
RBM25	huMAP3_00347.1 huMAP3_04407.1 huMAP3_04663.1 huMAP3_05316.1 huMAP3_05499.1 huMAP3_06487.1 huMAP3_07096.1 huMAP3_08305.1 huMAP3_08675.1 huMAP3_08947.1 huMAP3_09450.1 huMAP3_09943.1 huMAP3_10010.1 huMAP3_10250.1 huMAP3_11073.1 huMAP3_11453.1 huMAP3_12815.1 huMAP3_13567.1 huMAP3_13743.1
SRRM2	huMAP3_02403.1 huMAP3_05322.1 huMAP3_05748.1 huMAP3_06391.1 huMAP3_06487.1 huMAP3_07267.1 huMAP3_07659.1 huMAP3_07967.1 huMAP3_08675.1 huMAP3_09438.1 huMAP3_09621.1 huMAP3_09888.1 huMAP3_09943.1 huMAP3_10010.1 huMAP3_10250.1 huMAP3_10564.1 huMAP3_11073.1
SRSF11	huMAP3_00347.1 huMAP3_05322.1 huMAP3_05748.1 huMAP3_06487.1 huMAP3_07659.1 huMAP3_07835.1 huMAP3_07967.1 huMAP3_08675.1 huMAP3_09438.1 huMAP3_09621.1 huMAP3_09888.1 huMAP3_09943.1 huMAP3_10010.1 huMAP3_10250.1 huMAP3_11073.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_08675.1