hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08707.1
Complex Portal: CPX-14266
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ID3 | DNA-binding protein inhibitor ID-3 (Class B basic helix-loop-helix protein 25) (bHLHb25) (Helix-loop-helix protein HEIR-1) (ID-like protein inhibitor HLH 1R21) (Inhibitor of DNA binding 3) (Inhibitor of differentiation 3) | 5 | UniProt NCBI |
| TCF24 | Transcription factor 24 (TCF-24) | 3 | UniProt NCBI |
| TWIST1 | Twist-related protein 1 (Class A basic helix-loop-helix protein 38) (bHLHa38) (H-twist) | 5 | UniProt NCBI |
| TCF4 | Transcription factor 4 (TCF-4) (Class B basic helix-loop-helix protein 19) (bHLHb19) (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2) | 5 | UniProt NCBI |
| NEUROD1 | Neurogenic differentiation factor 1 (NeuroD) (NeuroD1) (Class A basic helix-loop-helix protein 3) (bHLHa3) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP236 | 0.0143443436167 | 0.5 | ID3 TWIST1 | Adipogenesis |
| CORUM:2635 | 0.049938562206 | 0.25 | NEUROD1 | BETA2-Cyclin D1 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| TCF4 | TWIST1 | 0.992 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| TCF4 | ID3 | 0.987 | 0.078 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| TCF4 | TCF24 | 0.972 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| TCF4 | NEUROD1 | 0.957 | 0.102 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| TWIST1 | ID3 | 0.572 | bioplex_WMM bioplex3_WMM WMM_only | ||
| ID3 | TCF24 | 0.557 |
mutually_exclusive (P15884)
|
bioplex_WMM bioplex3_WMM WMM_only | |
| TWIST1 | TCF24 | 0.502 |
mutually_exclusive (P15884)
|
bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes