hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08716.1
Complex Portal: CPX-16151
Confidence: High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
ATP5PD | ATP synthase subunit d, mitochondrial (ATPase subunit d) (ATP synthase peripheral stalk subunit d) | 5 | UniProt   NCBI |
ATP5F1D | ATP synthase subunit delta, mitochondrial (ATP synthase F1 subunit delta) (F-ATPase delta subunit) | 5 | UniProt   NCBI |
ATP5F1E | ATP synthase subunit epsilon, mitochondrial (ATPase subunit epsilon) (ATP synthase F1 subunit epsilon) | 5 | UniProt   NCBI |
MT-ATP8 | ATP synthase protein 8 (A6L) (F-ATPase subunit 8) | 5 | UniProt   NCBI |
ATP5PB | ATP synthase F(0) complex subunit B1, mitochondrial (ATP synthase peripheral stalk-membrane subunit b) (ATP synthase proton-transporting mitochondrial F(0) complex subunit B1) (ATP synthase subunit b) (ATPase subunit b) | 5 | UniProt   NCBI |
ZFYVE27 | Protrudin (Spastic paraplegia 33 protein) (Zinc finger FYVE domain-containing protein 27) | 5 | UniProt   NCBI |
ATP5F1C | ATP synthase subunit gamma, mitochondrial (ATP synthase F1 subunit gamma) (F-ATPase gamma subunit) | 5 | UniProt   NCBI |
ATP5F1B | ATP synthase subunit beta, mitochondrial (EC 7.1.2.2) (ATP synthase F1 subunit beta) | 5 | UniProt   NCBI |
ATP5ME | ATP synthase subunit e, mitochondrial (ATPase subunit e) (ATP synthase membrane subunit e) [Cleaved into: ATP synthase subunit e, mitochondrial, N-terminally processed] | 4 | UniProt   NCBI |
SLC43A3 | Equilibrative nucleobase transporter 1 (Protein FOAP-13) (Solute carrier family 43 member 3) | 5 | UniProt   NCBI |
ATP5MG | ATP synthase subunit g, mitochondrial (ATPase subunit g) (ATP synthase membrane subunit g) | 4 | UniProt   NCBI |
NTSR1 | Neurotensin receptor type 1 (NT-R-1) (NTR1) (High-affinity levocabastine-insensitive neurotensin receptor) (NTRH) | 5 | UniProt   NCBI |
ATP5MC1 | ATP synthase F(0) complex subunit C1, mitochondrial (ATP synthase lipid-binding protein) (ATP synthase membrane subunit c locus 1) (ATP synthase proteolipid P1) (ATP synthase proton-transporting mitochondrial F(0) complex subunit C1) (ATPase protein 9) (ATPase subunit c) | 5 | UniProt   NCBI |
MT-ATP6 | ATP synthase subunit a (F-ATPase protein 6) | 5 | UniProt   NCBI |
ATP5IF1 | ATPase inhibitor, mitochondrial (ATP synthase F1 subunit epsilon) (Inhibitor of F(1)F(o)-ATPase) (IF(1)) (IF1) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  CORUM:563 | 8.67840833502e-30 | 0.769230769231 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | F1F0-ATP synthase, mitochondrial |
  REAC:R-HSA-163210 | 1.1332345532e-22 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | Formation of ATP by chemiosmotic coupling |
  REAC:R-HSA-8949613 | 3.3248511231e-20 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | Cristae formation |
  GO:0045259 | 1.25279063813e-19 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | proton-transporting ATP synthase complex |
  GO:0005753 | 1.25279063813e-19 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | mitochondrial proton-transporting ATP synthase complex |
  WP:WP111 | 3.76834252364e-18 | 0.769230769231 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | Electron transport chain OXPHOS system in mitochondria |
  GO:0046933 | 1.6033625463e-17 | 0.615384615385 | ATP5F1E MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | proton-transporting ATP synthase activity, rotational mechanism |
  GO:0015252 | 2.53125015254e-16 | 0.615384615385 | ATP5F1E MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | proton channel activity |
  GO:0016469 | 3.00450260511e-16 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | proton-transporting two-sector ATPase complex |
  REAC:R-HSA-1592230 | 1.05397136061e-15 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | Mitochondrial biogenesis |
  KEGG:00190 | 5.80108508507e-15 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | Oxidative phosphorylation |
  REAC:R-HSA-163200 | 2.56682326947e-14 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
  GO:0015986 | 2.73851340382e-14 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | proton motive force-driven ATP synthesis |
  GO:0006754 | 1.23036107138e-13 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | ATP biosynthetic process |
  GO:0009145 | 1.54483436387e-13 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | purine nucleoside triphosphate biosynthetic process |
  GO:0009206 | 1.54483436387e-13 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | purine ribonucleoside triphosphate biosynthetic process |
  GO:0009201 | 2.66401999375e-13 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | ribonucleoside triphosphate biosynthetic process |
  GO:0046034 | 3.54902490281e-13 | 0.769230769231 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | ATP metabolic process |
  GO:0009142 | 3.63839224248e-13 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | nucleoside triphosphate biosynthetic process |
  REAC:R-HSA-1428517 | 5.60236791802e-13 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | The citric acid (TCA) cycle and respiratory electron transport |
  KEGG:04714 | 6.87038591331e-13 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | Thermogenesis |
  GO:0009205 | 7.28383651355e-13 | 0.769230769231 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | purine ribonucleoside triphosphate metabolic process |
  GO:0009144 | 8.17096489688e-13 | 0.769230769231 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | purine nucleoside triphosphate metabolic process |
  GO:0009199 | 1.0242346795e-12 | 0.769230769231 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | ribonucleoside triphosphate metabolic process |
  GO:0009141 | 1.5028794329e-12 | 0.769230769231 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | nucleoside triphosphate metabolic process |
  WP:WP623 | 2.37860293681e-12 | 0.538461538462 | ATP5F1E MT-ATP6 ATP5ME ATP5F1B ATP5MC1 ATP5MG ATP5PD | Oxidative phosphorylation |
  GO:0042776 | 4.7562656541e-12 | 0.615384615385 | ATP5F1E MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | proton motive force-driven mitochondrial ATP synthesis |
  GO:1904949 | 1.69618926822e-11 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | ATPase complex |
  GO:0098800 | 2.8425571188e-11 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | inner mitochondrial membrane protein complex |
  REAC:R-HSA-1852241 | 4.74839882195e-11 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | Organelle biogenesis and maintenance |
  GO:0009152 | 5.21085035855e-11 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | purine ribonucleotide biosynthetic process |
  GO:0009260 | 8.69778522089e-11 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | ribonucleotide biosynthetic process |
  GO:0015078 | 1.13303383941e-10 | 0.615384615385 | ATP5F1E MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | proton transmembrane transporter activity |
  GO:0046390 | 1.20487894289e-10 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | ribose phosphate biosynthetic process |
  GO:0009150 | 2.45593689475e-10 | 0.769230769231 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | purine ribonucleotide metabolic process |
  GO:0006164 | 2.5922088077e-10 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | purine nucleotide biosynthetic process |
  GO:0072522 | 3.29997118928e-10 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | purine-containing compound biosynthetic process |
  GO:0009259 | 3.36902440676e-10 | 0.769230769231 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | ribonucleotide metabolic process |
  GO:0019693 | 4.86016104901e-10 | 0.769230769231 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | ribose phosphate metabolic process |
  GO:0009165 | 6.8562079642e-10 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | nucleotide biosynthetic process |
  GO:1901293 | 8.15757370427e-10 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | nucleoside phosphate biosynthetic process |
  GO:0006119 | 8.83393810385e-10 | 0.615384615385 | ATP5F1E MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | oxidative phosphorylation |
  GO:0006163 | 1.7209672811e-09 | 0.769230769231 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | purine nucleotide metabolic process |
  GO:0072521 | 2.60136357929e-09 | 0.769230769231 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | purine-containing compound metabolic process |
  KEGG:05415 | 3.81363038228e-09 | 0.538461538462 | ATP5F1E MT-ATP6 ATP5F1B ATP5F1C MT-ATP8 ATP5MC1 ATP5PD | Diabetic cardiomyopathy |
  GO:0016874 | 4.02100545364e-09 | 0.615384615385 | ATP5F1E MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | ligase activity |
  GO:0009117 | 4.36340447824e-09 | 0.769230769231 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | nucleotide metabolic process |
  GO:0006753 | 5.03377488921e-09 | 0.769230769231 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | nucleoside phosphate metabolic process |
  GO:0009060 | 5.9532287785e-09 | 0.615384615385 | ATP5F1E MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | aerobic respiration |
  KEGG:05208 | 7.94732360012e-09 | 0.538461538462 | ATP5F1E MT-ATP6 ATP5F1B ATP5F1C MT-ATP8 ATP5MC1 ATP5PD | Chemical carcinogenesis - reactive oxygen species |
  GO:0098798 | 1.20103540618e-08 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | mitochondrial protein-containing complex |
  GO:0045333 | 1.65830362317e-08 | 0.615384615385 | ATP5F1E MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | cellular respiration |
  GO:0055086 | 1.67222552621e-08 | 0.769230769231 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | nucleobase-containing small molecule metabolic process |
  KEGG:05012 | 2.51235693434e-08 | 0.538461538462 | ATP5F1E MT-ATP6 ATP5F1B ATP5F1C MT-ATP8 ATP5MC1 ATP5PD | Parkinson disease |
  KEGG:05020 | 3.077606653e-08 | 0.538461538462 | ATP5F1E MT-ATP6 ATP5F1B ATP5F1C MT-ATP8 ATP5MC1 ATP5PD | Prion disease |
  GO:0006091 | 5.32020935169e-08 | 0.692307692308 | ATP5F1E MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | generation of precursor metabolites and energy |
  KEGG:05016 | 6.22805821717e-08 | 0.538461538462 | ATP5F1E MT-ATP6 ATP5F1B ATP5F1C MT-ATP8 ATP5MC1 ATP5PD | Huntington disease |
  GO:0005261 | 6.48840857751e-08 | 0.615384615385 | ATP5F1E MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | monoatomic cation channel activity |
  GO:0015980 | 1.56201452236e-07 | 0.615384615385 | ATP5F1E MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | energy derivation by oxidation of organic compounds |
  KEGG:05014 | 2.16053824801e-07 | 0.538461538462 | ATP5F1E MT-ATP6 ATP5F1B ATP5F1C MT-ATP8 ATP5MC1 ATP5PD | Amyotrophic lateral sclerosis |
  GO:0005743 | 2.18288156e-07 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | mitochondrial inner membrane |
  KEGG:05010 | 3.01924492621e-07 | 0.538461538462 | ATP5F1E MT-ATP6 ATP5F1B ATP5F1C MT-ATP8 ATP5MC1 ATP5PD | Alzheimer disease |
  GO:0019866 | 3.63953838672e-07 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | organelle inner membrane |
  GO:0090407 | 5.0024298364e-07 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | organophosphate biosynthetic process |
  GO:0005216 | 5.88847130332e-07 | 0.615384615385 | ATP5F1E MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | monoatomic ion channel activity |
  KEGG:05022 | 1.17925452906e-06 | 0.538461538462 | ATP5F1E MT-ATP6 ATP5F1B ATP5F1C MT-ATP8 ATP5MC1 ATP5PD | Pathways of neurodegeneration - multiple diseases |
  GO:0019637 | 1.26547876213e-06 | 0.769230769231 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | organophosphate metabolic process |
  GO:0015267 | 1.36208084472e-06 | 0.615384615385 | ATP5F1E MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | channel activity |
  GO:0022803 | 1.39988151871e-06 | 0.615384615385 | ATP5F1E MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | passive transmembrane transporter activity |
  GO:1901137 | 1.55110439382e-06 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | carbohydrate derivative biosynthetic process |
  WP:WP4932 | 1.58754653326e-06 | 0.384615384615 | ATP5F1E ATP5MC1 MT-ATP6 MT-ATP8 ATP5F1B | 7q11 23 copy number variation syndrome |
  GO:1901135 | 2.48484092956e-06 | 0.769230769231 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | carbohydrate derivative metabolic process |
  GO:0031966 | 4.43583551626e-06 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | mitochondrial membrane |
  GO:0022890 | 4.59713724824e-06 | 0.615384615385 | ATP5F1E MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | inorganic cation transmembrane transporter activity |
  GO:0005740 | 7.92804773905e-06 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | mitochondrial envelope |
  GO:0008324 | 9.01914988014e-06 | 0.615384615385 | ATP5F1E MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | monoatomic cation transmembrane transporter activity |
  KEGG:01100 | 9.78494016245e-06 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | Metabolic pathways |
  GO:0015318 | 2.04016528965e-05 | 0.615384615385 | ATP5F1E MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | inorganic molecular entity transmembrane transporter activity |
  GO:0022857 | 3.42591113281e-05 | 0.692307692308 | ATP5F1E MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD SLC43A3 ATP5MG | transmembrane transporter activity |
  GO:0015075 | 3.63759964577e-05 | 0.615384615385 | ATP5F1E MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | monoatomic ion transmembrane transporter activity |
  GO:0005215 | 9.34734875731e-05 | 0.692307692308 | ATP5F1E MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD SLC43A3 ATP5MG | transporter activity |
  GO:0044281 | 0.000199219030961 | 0.769230769231 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | small molecule metabolic process |
  GO:0000275 | 0.000274621184043 | 0.230769230769 | ATP5F1E ATP5F1C ATP5F1B | mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1) |
  GO:0005739 | 0.000289450402857 | 0.769230769231 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | mitochondrion |
  GO:1901566 | 0.000291666893299 | 0.769230769231 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | organonitrogen compound biosynthetic process |
  HP:0001987 | 0.000412326119611 | 0.307692307692 | ATP5F1E MT-ATP6 MT-ATP8 ATP5F1B | Hyperammonemia |
  GO:0031967 | 0.000432736455895 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | organelle envelope |
  GO:0031975 | 0.000432736455895 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | envelope |
  GO:0098796 | 0.000436883628298 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | membrane protein complex |
  GO:0045261 | 0.000548960443183 | 0.230769230769 | ATP5F1E ATP5F1C ATP5F1B | proton-transporting ATP synthase complex, catalytic core F(1) |
  REAC:R-HSA-1430728 | 0.0006865042136 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | Metabolism |
  HP:0003535 | 0.0014715757271 | 0.230769230769 | ATP5F1E MT-ATP8 MT-ATP6 | 3-Methylglutaconic aciduria |
  GO:0045263 | 0.00153551162834 | 0.230769230769 | ATP5MC1 ATP5PD ATP5MG | proton-transporting ATP synthase complex, coupling factor F(o) |
  GO:0000276 | 0.00153551162834 | 0.230769230769 | ATP5MC1 ATP5PD ATP5MG | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o) |
  HP:0001258 | 0.00158693525954 | 0.307692307692 | ATP5F1E MT-ATP6 MT-ATP8 ZFYVE27 | Spastic paraplegia |
  HP:0010550 | 0.00393286154744 | 0.307692307692 | ATP5F1E MT-ATP6 MT-ATP8 ZFYVE27 | Paraplegia |
  HP:0002445 | 0.00437296709122 | 0.230769230769 | ATP5F1E MT-ATP8 MT-ATP6 | Tetraplegia |
  GO:0006796 | 0.0059085021496 | 0.769230769231 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | phosphate-containing compound metabolic process |
  GO:0033177 | 0.00601998990141 | 0.230769230769 | ATP5MC1 ATP5PD ATP5MG | proton-transporting two-sector ATPase complex, proton-transporting domain |
  GO:0006793 | 0.00648782435812 | 0.769230769231 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5IF1 ATP5MG | phosphorus metabolic process |
  HP:0003112 | 0.00700506604878 | 0.307692307692 | ATP5F1E MT-ATP6 MT-ATP8 ATP5F1B | Abnormal circulating amino acid concentration |
  HP:0002157 | 0.00719474349145 | 0.307692307692 | ATP5F1E MT-ATP6 MT-ATP8 ATP5F1B | Azotemia |
  HP:0004364 | 0.00930729156648 | 0.307692307692 | ATP5F1E MT-ATP6 MT-ATP8 ATP5F1B | Abnormal circulating nitrogen compound concentration |
  GO:0033178 | 0.018559526455 | 0.230769230769 | ATP5F1E ATP5F1C ATP5F1B | proton-transporting two-sector ATPase complex, catalytic domain |
  HP:0010551 | 0.0195968748837 | 0.307692307692 | ATP5F1E MT-ATP6 MT-ATP8 ZFYVE27 | Paraplegia/paraparesis |
  HP:0003348 | 0.0200069455336 | 0.230769230769 | ATP5F1E MT-ATP8 MT-ATP6 | Hyperalaninemia |
  HP:0010915 | 0.021013443882 | 0.230769230769 | ATP5F1E MT-ATP8 MT-ATP6 | Abnormal circulating pyruvate family amino acid concentration |
  HP:0010916 | 0.021013443882 | 0.230769230769 | ATP5F1E MT-ATP8 MT-ATP6 | Abnormal circulating alanine concentration |
  HP:0002061 | 0.0239282920546 | 0.307692307692 | ATP5F1E MT-ATP6 MT-ATP8 ZFYVE27 | Lower limb spasticity |
  HP:0033108 | 0.0316097192986 | 0.230769230769 | ATP5F1E MT-ATP8 MT-ATP6 | Abnormal circulating proteinogenic amino acid derivative concentration |
  GO:1902494 | 0.0352829702563 | 0.692307692308 | ATP5F1E ATP5MC1 MT-ATP6 ATP5ME ATP5F1B ATP5F1C MT-ATP8 ATP5PD ATP5MG | catalytic complex |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap |
---|---|---|---|---|
 ATP5F1D |  ATP5PB | 1.0 | 0.934           |          |
 ATP5PB |  ATP5ME | 1.0 | 0.96           |          |
 ATP5F1D |  ATP5F1B | 1.0 | 0.896           |
structurally_consistent (P36542)        
|
 ATP5F1D |  ATP5ME | 1.0 | 0.87           |          |
 ATP5PD |  ATP5PB | 1.0 | 0.93           |
structurally_consistent (dimer)        
|
 ATP5F1D |  ATP5F1C | 1.0 | 0.9           |
structurally_consistent (dimer)        
|
 ATP5PB |  ATP5MG | 1.0 | 0.93           |
structurally_consistent (dimer)        
|
 ATP5F1C |  ATP5F1B | 1.0 | 0.972           |
structurally_consistent (dimer)        
|
 ATP5PD |  ATP5F1D | 1.0 | 0.926           |
structurally_consistent (P25705)        
|
 ATP5PD |  ATP5ME | 1.0 | 0.916           |          |
 ATP5F1D |  ATP5MG | 1.0 | 0.826           |          |
 ATP5F1D |  ATP5F1E | 1.0 | 0.88           |          |
 ATP5PD |  ATP5F1B | 1.0 | 0.892           |          |
 ATP5ME |  ATP5MG | 1.0 | 0.908           |          |
 ATP5F1B |  ATP5MG | 1.0 | 0.916           |          |
 ATP5F1C |  ATP5MG | 1.0 | 0.964           |          |
 ATP5PB |  ATP5F1B | 1.0 | 0.938           |
structurally_consistent (P48047)        
|
 ATP5PB |  MT-ATP6 | 1.0 | 0.826           |
structurally_consistent (dimer)        
|
 ATP5PD |  ATP5F1C | 0.999 | 0.886           |
structurally_consistent (P00846)        
|
 ATP5PB |  ATP5F1C | 0.999 | 0.962           |
structurally_consistent (P00846)        
|
 ATP5ME |  ATP5F1B | 0.999 | 0.922           |          |
 ATP5F1D |  MT-ATP6 | 0.999 | 0.898           |          |
 ATP5ME |  ATP5F1C | 0.999 | 0.754           |          |
 ATP5PD |  ATP5MG | 0.999 | 0.976           |
structurally_consistent (P24539)        
|
 ZFYVE27 |  ATP5PB | 0.999 | 0.09           |          |
 MT-ATP8 |  MT-ATP6 | 0.998 | 0.408           |          |
 ATP5PB |  MT-ATP8 | 0.998 | 0.728           |          |
 ATP5ME |  ATP5F1E | 0.998 | 0.914           |          |
 MT-ATP6 |  ATP5F1B | 0.997 | 0.816           |          |
 ATP5IF1 |  ATP5F1E | 0.997 | 0.556           |          |
 SLC43A3 |  ATP5F1B | 0.996 | 0.172           |          |
 ATP5F1E |  ATP5MG | 0.996 | 0.802           |          |
 ATP5PD |  ATP5IF1 | 0.996 | 0.728           |
structurally_consistent (dimer)        
|
 MT-ATP6 |  ATP5ME | 0.996 | 0.914           |          |
 MT-ATP6 |  ATP5MG | 0.995 | 0.858           |
structurally_consistent (P24539)        
|
 ATP5PD |  ATP5F1E | 0.995 | 0.728           |          |
 ATP5F1D |  ATP5IF1 | 0.995 | 0.424           |          |
 ATP5F1C |  ATP5F1E | 0.994 | 0.762           |
structurally_consistent (dimer)        
|
 MT-ATP8 |  ATP5F1B | 0.994 | 0.682           |          |
 ZFYVE27 |  ATP5F1B | 0.994 | 0.11           |          |
 ATP5F1E |  ATP5F1B | 0.994 | 0.72           |          |
 ATP5PD |  MT-ATP6 | 0.994 | 0.84           |
structurally_consistent (dimer)        
|
 ATP5F1D |  MT-ATP8 | 0.994 | 0.676           |          |
 ATP5PB |  ATP5IF1 | 0.993 | 0.684           |          |
 MT-ATP6 |  ATP5IF1 | 0.993 | 0.248           |
structurally_consistent (O75947)        
|
 MT-ATP6 |  ATP5F1C | 0.993 | 0.872           |
structurally_consistent (dimer)        
|
 MT-ATP8 |  ATP5ME | 0.992 | 0.654           |          |
 MT-ATP8 |  ATP5F1C | 0.992 | 0.67           |          |
 ZFYVE27 |  ATP5F1C | 0.992 | 0.092           |          |
 ATP5PB |  ATP5F1E | 0.991 | 0.64           |          |
 ATP5PB |  SLC43A3 | 0.99 | 0.126           |          |
 ATP5IF1 |  ATP5ME | 0.99 | 0.256           |          |
 ATP5PD |  ZFYVE27 | 0.989 | 0.136           |          |
 ZFYVE27 |  ATP5ME | 0.988 | 0.096           |          |
 MT-ATP8 |  ATP5IF1 | 0.984 | 0.114           |          |
 ATP5PB |  NTSR1 | 0.984 |            |          |
 ATP5PD |  SLC43A3 | 0.981 | 0.092           |          |
 ATP5IF1 |  ATP5F1B | 0.98 | 0.546           |          |
 ATP5IF1 |  NTSR1 | 0.976 |            |          |
 ZFYVE27 |  ATP5MG | 0.972 | 0.16           |          |
 ZFYVE27 |  MT-ATP8 | 0.969 | 0.058           |          |
 ATP5PB |  ATP5MC1 | 0.966 |            |          |
 SLC43A3 |  ATP5MG | 0.965 | 0.054           |          |
 MT-ATP8 |  ATP5F1E | 0.964 | 0.296           |          |
 MT-ATP8 |  ATP5MG | 0.963 | 0.676           |          |
 ATP5PD |  MT-ATP8 | 0.961 | 0.632           |          |
 NTSR1 |  ATP5F1C | 0.96 |            |          |
 ZFYVE27 |  ATP5F1E | 0.956 | 0.09           |          |
 ATP5F1C |  ATP5MC1 | 0.954 |            |          |
 ATP5F1B |  ATP5MC1 | 0.948 |            |          |
 ATP5IF1 |  ATP5MG | 0.938 | 0.502           |          |
 ATP5F1D |  ZFYVE27 | 0.931 | 0.092           |          |
 ATP5MC1 |  ATP5MG | 0.931 |            |          |
 SLC43A3 |  ATP5ME | 0.929 | 0.028           |          |
 ATP5ME |  ATP5MC1 | 0.923 |            |          |
 ATP5PD |  ATP5MC1 | 0.922 |            |          |
 ZFYVE27 |  ATP5IF1 | 0.895 | 0.068           |          |
 ATP5IF1 |  ATP5F1C | 0.878 | 0.438           |          |
 SLC43A3 |  ATP5F1C | 0.86 | 0.058           |          |
 ATP5F1D |  SLC43A3 | 0.828 | 0.106           |          |
 ATP5ME |  NTSR1 | 0.822 |            |          |
 ATP5PD |  NTSR1 | 0.817 |            |          |
 MT-ATP6 |  ATP5F1E | 0.816 | 0.864           |
structurally_consistent (P36542)        
|
 MT-ATP8 |  ATP5MC1 | 0.708 |            |          |
 NTSR1 |  ATP5F1B | 0.697 |            |          |
 ATP5F1D |  NTSR1 | 0.632 |            |          |
 NTSR1 |  ATP5MG | 0.604 |            |          |
 SLC43A3 |  ATP5F1E | 0.586 | 0.066           |          |
 ATP5F1E |  ATP5MC1 | 0.569 |            |          |
 ATP5F1D |  ATP5MC1 | 0.543 |            |          |
 MT-ATP6 |  ATP5MC1 | 0.388 |            |          |
 SLC43A3 |  ATP5IF1 | 0.386 | 0.058           |          |
 MT-ATP8 |  SLC43A3 | 0.372 | 0.04           |          |
 SLC43A3 |  MT-ATP6 | 0.357 | 0.034           |          |
 SLC43A3 |  ATP5MC1 | 0.348 |            |          |
 SLC43A3 |  NTSR1 | 0.298 |            |          |
 ATP5IF1 |  ATP5MC1 | 0.278 |            |          |
 NTSR1 |  ATP5MC1 | 0.25 |            |          |
 MT-ATP6 |  NTSR1 | 0.243 |            |          |
 NTSR1 |  ATP5F1E | 0.18 |            |          |
 MT-ATP8 |  NTSR1 | 0.16 |            |          |
 ZFYVE27 |  MT-ATP6 | 0.076 | 0.102           |          |
 ZFYVE27 |  SLC43A3 | 0.042 | 0.07           |          |
 ZFYVE27 |  NTSR1 | 0.026 |            |          |
Related Complexes