hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08728.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TTC3 | E3 ubiquitin-protein ligase TTC3 (EC 2.3.2.27) (Protein DCRR1) (RING finger protein 105) (RING-type E3 ubiquitin transferase TTC3) (TPR repeat protein D) (Tetratricopeptide repeat protein 3) (TPR repeat protein 3) | 5 | UniProt NCBI |
| RNF214 | RING finger protein 214 | 2 | UniProt NCBI |
| PIK3R4 | Phosphoinositide 3-kinase regulatory subunit 4 (PI3-kinase regulatory subunit 4) (EC 2.7.11.1) (PI3-kinase p150 subunit) (Phosphoinositide 3-kinase adaptor protein) | 5 | UniProt NCBI |
| HPS5 | BLOC-2 complex member HPS5 (Alpha-integrin-binding protein 63) (Hermansky-Pudlak syndrome 5 protein) (Ruby-eye protein 2 homolog) (Ru2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP5156 | 0.0124405187696 | 0.25 | PIK3R4 | SARS CoV 2 replication organelle formation |
| CORUM:429 | 0.049938562206 | 0.25 | PIK3R4 | Phosphatidylinositol 3-kinase complex (PIK3C3, PIK3R4) |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| TTC3 | HPS5 | 0.987 | 0.072 | hein_WMM bioplex3_WMM WMM_only |
| PIK3R4 | HPS5 | 0.985 | 0.058 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only |
| TTC3 | RNF214 | 0.977 | 0.1 | youn () bioplex3_HEK293 bioplex3_WMM youn_WMM WMM_only |
| PIK3R4 | TTC3 | 0.95 | 0.07 | hein_WMM bioplex3_WMM youn_WMM WMM_only |
| PIK3R4 | RNF214 | 0.047 | 0.078 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only |
| RNF214 | HPS5 | 0.029 | 0.094 | bioplex3_WMM WMM_only |
Related Complexes