hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08801.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KCNJ10 | ATP-sensitive inward rectifier potassium channel 10 (ATP-dependent inwardly rectifying potassium channel Kir4.1) (Inward rectifier K(+) channel Kir1.2) (Potassium channel, inwardly rectifying subfamily J member 10) | 5 | UniProt NCBI |
| KCNMB3 | Calcium-activated potassium channel subunit beta-3 (BK channel subunit beta-3) (BKbeta3) (Hbeta3) (Calcium-activated potassium channel, subfamily M subunit beta-3) (Charybdotoxin receptor subunit beta-3) (K(VCA)beta-3) (Maxi K channel subunit beta-3) (Slo-beta-3) | 5 | UniProt NCBI |
| KCNJ12 | ATP-sensitive inward rectifier potassium channel 12 (Inward rectifier K(+) channel Kir2.2) (IRK-2) (Inward rectifier K(+) channel Kir2.2v) (Potassium channel, inwardly rectifying subfamily J member 12) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1296071 | 2.13517139789e-05 | 1.0 | KCNJ10 KCNMB3 KCNJ12 | Potassium Channels |
| REAC:R-HSA-1296041 | 0.00172341693863 | 0.666666666667 | KCNJ10 KCNJ12 | Activation of G protein gated Potassium channels |
| REAC:R-HSA-1296059 | 0.00172341693863 | 0.666666666667 | KCNJ10 KCNJ12 | G protein gated Potassium channels |
| REAC:R-HSA-997272 | 0.00172341693863 | 0.666666666667 | KCNJ10 KCNJ12 | Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| REAC:R-HSA-112316 | 0.00203732306248 | 1.0 | KCNJ10 KCNMB3 KCNJ12 | Neuronal System |
| REAC:R-HSA-1296065 | 0.00239054881557 | 0.666666666667 | KCNJ10 KCNJ12 | Inwardly rectifying K+ channels |
| GO:0005267 | 0.00345936027834 | 1.0 | KCNJ10 KCNMB3 KCNJ12 | potassium channel activity |
| REAC:R-HSA-991365 | 0.00359505378021 | 0.666666666667 | KCNJ10 KCNJ12 | Activation of GABAB receptors |
| REAC:R-HSA-977444 | 0.00359505378021 | 0.666666666667 | KCNJ10 KCNJ12 | GABA B receptor activation |
| REAC:R-HSA-977443 | 0.005581186855 | 0.666666666667 | KCNJ10 KCNJ12 | GABA receptor activation |
| GO:0015079 | 0.00949377645712 | 1.0 | KCNJ10 KCNMB3 KCNJ12 | potassium ion transmembrane transporter activity |
| GO:0099094 | 0.00949377645712 | 1.0 | KCNJ10 KCNMB3 KCNJ12 | ligand-gated monoatomic cation channel activity |
| GO:0015276 | 0.0180186629002 | 1.0 | KCNJ10 KCNMB3 KCNJ12 | ligand-gated monoatomic ion channel activity |
| GO:0022834 | 0.0180186629002 | 1.0 | KCNJ10 KCNMB3 KCNJ12 | ligand-gated channel activity |
| GO:0006813 | 0.0360123345897 | 1.0 | KCNJ10 KCNMB3 KCNJ12 | potassium ion transport |
| REAC:R-HSA-1296053 | 0.0498224659464 | 0.333333333333 | KCNJ12 | Classical Kir channels |
| REAC:R-HSA-1296067 | 0.0498224659464 | 0.333333333333 | KCNJ10 | Potassium transport channels |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| KCNJ12 | KCNJ10 | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| KCNJ12 | KCNMB3 | 0.973 | bioplex3_HEK293 bioplex3_WMM WMM_only |
Related Complexes