hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08803.1
Complex Portal: CPX-19065
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KDM5C | Lysine-specific demethylase 5C (EC 1.14.11.67) (Histone demethylase JARID1C) (Jumonji/ARID domain-containing protein 1C) (Protein SmcX) (Protein Xe169) ([histone H3]-trimethyl-L-lysine(4) demethylase 5C) | 5 | UniProt NCBI |
| GTF3C5 | General transcription factor 3C polypeptide 5 (TF3C-epsilon) (Transcription factor IIIC 63 kDa subunit) (TFIIIC 63 kDa subunit) (TFIIIC63) (Transcription factor IIIC subunit epsilon) | 5 | UniProt NCBI |
| GTF3C3 | General transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) (TFIIIC 102 kDa subunit) (TFIIIC102) (Transcription factor IIIC subunit gamma) (TF3C-gamma) | 5 | UniProt NCBI |
| GTF3C1 | General transcription factor 3C polypeptide 1 (TF3C-alpha) (TFIIIC box B-binding subunit) (Transcription factor IIIC 220 kDa subunit) (TFIIIC 220 kDa subunit) (TFIIIC220) (Transcription factor IIIC subunit alpha) | 5 | UniProt NCBI |
| USP34 | Ubiquitin carboxyl-terminal hydrolase 34 (EC 3.4.19.12) (Deubiquitinating enzyme 34) (Ubiquitin thioesterase 34) (Ubiquitin-specific-processing protease 34) | 5 | UniProt NCBI |
| ZNF764 | Zinc finger protein 764 | 5 | UniProt NCBI |
| LASP1 | LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1105 | 7.02050133195e-08 | 0.428571428571 | GTF3C1 GTF3C5 GTF3C3 | transcription factor IIIC multisubunit complex |
| CORUM:1101 | 7.02050133195e-08 | 0.428571428571 | GTF3C1 GTF3C5 GTF3C3 | transcription factor IIIC multisubunit complex |
| CORUM:1113 | 7.02050133195e-08 | 0.428571428571 | GTF3C1 GTF3C5 GTF3C3 | 5S-DNA-TFIIIA-TFIIIC2 subcomplex |
| CORUM:1106 | 1.4038119659e-07 | 0.428571428571 | GTF3C1 GTF3C5 GTF3C3 | TFIIIC containing-TOP1-SUB1 complex |
| CORUM:1114 | 2.45616649736e-07 | 0.428571428571 | GTF3C1 GTF3C5 GTF3C3 | 5S-DNA-TFIIIA-TFIIIC2-TFIIIB subcomplex |
| REAC:R-HSA-76066 | 3.374300022e-05 | 0.428571428571 | GTF3C1 GTF3C5 GTF3C3 | RNA Polymerase III Transcription Initiation From Type 2 Promoter |
| REAC:R-HSA-76061 | 3.374300022e-05 | 0.428571428571 | GTF3C1 GTF3C5 GTF3C3 | RNA Polymerase III Transcription Initiation From Type 1 Promoter |
| GO:0000127 | 6.72425931667e-05 | 0.428571428571 | GTF3C1 GTF3C5 GTF3C3 | transcription factor TFIIIC complex |
| GO:0042791 | 6.72425931667e-05 | 0.428571428571 | GTF3C1 GTF3C5 GTF3C3 | 5S class rRNA transcription by RNA polymerase III |
| REAC:R-HSA-76046 | 7.75332089956e-05 | 0.428571428571 | GTF3C1 GTF3C5 GTF3C3 | RNA Polymerase III Transcription Initiation |
| REAC:R-HSA-74158 | 0.000118290093408 | 0.428571428571 | GTF3C1 GTF3C5 GTF3C3 | RNA Polymerase III Transcription |
| REAC:R-HSA-749476 | 0.000118290093408 | 0.428571428571 | GTF3C1 GTF3C5 GTF3C3 | RNA Polymerase III Abortive And Retractive Initiation |
| GO:0090576 | 0.0001882019462 | 0.428571428571 | GTF3C1 GTF3C5 GTF3C3 | RNA polymerase III transcription regulator complex |
| GO:0042797 | 0.00040312426486 | 0.428571428571 | GTF3C1 GTF3C5 GTF3C3 | tRNA transcription by RNA polymerase III |
| GO:0009304 | 0.000554182028596 | 0.428571428571 | GTF3C1 GTF3C5 GTF3C3 | tRNA transcription |
| GO:0000995 | 0.000738757615619 | 0.428571428571 | GTF3C1 GTF3C5 GTF3C3 | RNA polymerase III general transcription initiation factor activity |
| GO:0009303 | 0.0122273067778 | 0.428571428571 | GTF3C1 GTF3C5 GTF3C3 | rRNA transcription |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| GTF3C5 | GTF3C3 | 1.0 | 0.97 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () Malo gupta_WMM fraction boldt_WMM | |
| GTF3C1 | GTF3C3 | 1.0 | 0.866 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt youn_WMM hein () Malo gupta_WMM fraction boldt_WMM | |
| GTF3C5 | GTF3C1 | 1.0 | 0.684 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM | |
| GTF3C1 | ZNF764 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| GTF3C3 | ZNF764 | 0.998 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| ZNF764 | KDM5C | 0.995 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| GTF3C3 | KDM5C | 0.994 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| GTF3C1 | KDM5C | 0.99 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| GTF3C5 | KDM5C | 0.984 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| USP34 | ZNF764 | 0.98 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| GTF3C5 | ZNF764 | 0.952 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| LASP1 | ZNF764 | 0.951 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| GTF3C3 | USP34 | 0.488 | 0.104 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| GTF3C5 | USP34 | 0.39 | 0.078 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| USP34 | KDM5C | 0.082 | bioplex3_WMM WMM_only | ||
| USP34 | LASP1 | 0.055 | 0.032 | bioplex_WMM bioplex3_WMM WMM_only | |
| GTF3C1 | USP34 | 0.048 | 0.172 | bioplex_WMM bioplex3_WMM youn_WMM WMM_only treiber_WMM | |
| GTF3C5 | LASP1 | 0.012 | 0.006 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| GTF3C1 | LASP1 | 0.007 | 0.042 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| GTF3C3 | LASP1 | 0.007 | 0.024 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
Related Complexes