hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08814.1
Complex Portal: CPX-13835
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ST8SIA4 | CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase (EC 2.4.3.-) (Alpha-2,8-sialyltransferase 8D) (Polysialyltransferase) (Polysialyltransferase-1) (Sialyltransferase 8D) (SIAT8-D) (Sialyltransferase St8Sia IV) (ST8SiaIV) | 5 | UniProt NCBI |
| PON2 | Serum paraoxonase/arylesterase 2 (PON 2) (EC 3.1.1.2) (EC 3.1.1.81) (Aromatic esterase 2) (A-esterase 2) (Serum aryldialkylphosphatase 2) | 5 | UniProt NCBI |
| HLA-DQB1 | HLA class II histocompatibility antigen, DQ beta 1 chain (MHC class II antigen DQB1) | 5 | UniProt NCBI |
| IGF1R | Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] | 5 | UniProt NCBI |
| SELENOF | Selenoprotein F (15 kDa selenoprotein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0000711 | 0.00464946977244 | 0.6 | PON2 HLA-DQB1 IGF1R | Restlessness |
| WP:WP4217 | 0.0386238148414 | 0.4 | IGF1R HLA-DQB1 | Ebola virus infection in host |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| HLA-DQB1 | PON2 | 0.984 | 0.112 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| IGF1R | ST8SIA4 | 0.978 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| IGF1R | PON2 | 0.972 | 0.09 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| PON2 | SELENOF | 0.95 | 0.012 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 gupta_WMM | |
| ST8SIA4 | PON2 | 0.832 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| ST8SIA4 | SELENOF | 0.653 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| IGF1R | HLA-DQB1 | 0.439 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | ||
| HLA-DQB1 | ST8SIA4 | 0.418 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| HLA-DQB1 | SELENOF | 0.073 | 0.0922857142857 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| IGF1R | SELENOF | 0.022 | 0.04 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes