hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08828.1
Confidence: High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
TNFRSF1A | Tumor necrosis factor receptor superfamily member 1A (Tumor necrosis factor receptor 1) (TNF-R1) (Tumor necrosis factor receptor type I) (TNF-RI) (TNFR-I) (p55) (p60) (CD antigen CD120a) [Cleaved into: Tumor necrosis factor receptor superfamily member 1A, membrane form; Tumor necrosis factor-binding protein 1 (TBPI)] | 5 | UniProt   NCBI |
TNF | Tumor necrosis factor (Cachectin) (TNF-alpha) (Tumor necrosis factor ligand superfamily member 2) (TNF-a) [Cleaved into: Tumor necrosis factor, membrane form (N-terminal fragment) (NTF); Intracellular domain 1 (ICD1); Intracellular domain 2 (ICD2); C-domain 1; C-domain 2; Tumor necrosis factor, soluble form] | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  KEGG:05310 | 0.0273048944826 | 1.0 | TNF | Asthma |
  WP:WP4480 | 0.0363468011862 | 1.0 | TNF | Altered glycosylation of MUC1 in tumor microenvironment |
  WP:WP5414 | 0.0363468011862 | 1.0 | TNF | IDO metabolic pathway |
  WP:WP4891 | 0.0408901513344 | 1.0 | TNF | COVID 19 adverse outcome pathway |
  KEGG:01523 | 0.0417604268558 | 1.0 | TNF | Antifolate resistance |
  KEGG:05330 | 0.0433665971195 | 1.0 | TNF | Allograft rejection |
  WP:WP2813 | 0.0454335014827 | 1.0 | TNF | Mammary gland development pathway Embryonic development Stage 1 of 4 |
  WP:WP5336 | 0.0454335014827 | 1.0 | TNF | Induction of autophagy and toll like receptor signaling pathways by graphene oxide |
  KEGG:05143 | 0.0497912781742 | 1.0 | TNF | African trypanosomiasis |
  KEGG:05332 | 0.0497912781742 | 1.0 | TNF | Graft-versus-host disease |
  CORUM:6684 | 0.0499436884912 | 1.0 | TNF | TNFR2 signaling complex |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 TNFRSF1A |  TNF | 0.991 |            | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
Related Complexes