hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_08831.1

Complex Portal: CPX-17114

Confidence: High

Genename	Protein Name	Uniprot Annotation Score	Links
NKD1	Protein naked cuticle homolog 1 (Naked-1) (hNkd) (hNkd1)	5	UniProt NCBI
ROBO1	Roundabout homolog 1 (Deleted in U twenty twenty) (H-Robo-1)	5	UniProt NCBI
ANKRD18A	Ankyrin repeat domain-containing protein 18A	3	UniProt NCBI
RNF125	E3 ubiquitin-protein ligase RNF125 (EC 2.3.2.27) (RING finger protein 125) (T-cell RING activation protein 1) (TRAC-1)	5	UniProt NCBI
RND2	Rho-related GTP-binding protein RhoN (Rho family GTPase 2) (Rho-related GTP-binding protein Rho7) (Rnd2)	5	UniProt NCBI
MOV10L1	RNA helicase Mov10l1 (EC 3.6.4.13) (Moloney leukemia virus 10-like protein 1) (MOV10-like protein 1)	5	UniProt NCBI
MERTK	Tyrosine-protein kinase Mer (EC 2.7.10.1) (Proto-oncogene c-Mer) (Receptor tyrosine kinase MerTK)	5	UniProt NCBI
DIP2C	Disco-interacting protein 2 homolog C (DIP2 homolog C)	3	UniProt NCBI
RIMS4	Regulating synaptic membrane exocytosis protein 4 (RIM4 gamma) (Rab3-interacting molecule 4) (RIM 4)	4	UniProt NCBI
CDCA7	Cell division cycle-associated protein 7 (Protein JPO1)	5	UniProt NCBI
NBEAL1	Neurobeachin-like protein 1 (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 16 protein) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 17 protein)	3	UniProt NCBI
DACT1	Dapper homolog 1 (hDPR1) (Dapper antagonist of catenin 1) (Hepatocellular carcinoma novel gene 3 protein)	5	UniProt NCBI
PRICKLE2	Prickle-like protein 2	4	UniProt NCBI
CAPN15	Calpain-15 (EC 3.4.22.-) (Small optic lobes homolog)	5	UniProt NCBI
PRICKLE1	Prickle-like protein 1 (REST/NRSF-interacting LIM domain protein 1)	5	UniProt NCBI
ANKIB1	Ankyrin repeat and IBR domain-containing protein 1 (EC 2.3.2.31)	5	UniProt NCBI
MATCAP2	Putative tyrosine carboxypeptidase MATCAP2 (EC 3.4.17.-)	4	UniProt NCBI
NRSN2	Neurensin-2	3	UniProt NCBI
KCNE3	Potassium voltage-gated channel subfamily E member 3 (MinK-related peptide 2) (Minimum potassium ion channel-related peptide 2) (Potassium channel subunit beta MiRP2)	5	UniProt NCBI
TC2N	Tandem C2 domains nuclear protein (Membrane targeting tandem C2 domain-containing protein 1) (Tandem C2 protein in nucleus) (Tac2-N)	3	UniProt NCBI
SECISBP2	Selenocysteine insertion sequence-binding protein 2 (SECIS-binding protein 2)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0060071	0.00801101001073	0.190476190476	DACT1 PRICKLE1 NKD1 PRICKLE2	Wnt signaling pathway, planar cell polarity pathway
GO:0035567	0.0475367859374	0.190476190476	DACT1 PRICKLE1 NKD1 PRICKLE2	non-canonical Wnt signaling pathway
WP:WP428	0.0478135573658	0.142857142857	PRICKLE1 NKD1 PRICKLE2	Wnt signaling

Edges

Protein 1	Protein 2	Score	ProteomeHD
PRICKLE1	KCNE3	0.999
KCNE3	CAPN15	0.999
ANKIB1	KCNE3	0.999
KCNE3	NBEAL1	0.998
DIP2C	KCNE3	0.998
TC2N	KCNE3	0.998
MOV10L1	KCNE3	0.997
KCNE3	PRICKLE2	0.988
CDCA7	KCNE3	0.988
ANKRD18A	KCNE3	0.988
KCNE3	RND2	0.988
NKD1	KCNE3	0.986
KCNE3	RNF125	0.986
NRSN2	KCNE3	0.98
RIMS4	KCNE3	0.978
KCNE3	SECISBP2	0.973
KCNE3	DACT1	0.972
MATCAP2	KCNE3	0.971
KCNE3	MERTK	0.956
ROBO1	KCNE3	0.951
DIP2C	PRICKLE1	0.946
PRICKLE1	CAPN15	0.916
TC2N	MOV10L1	0.904
TC2N	PRICKLE1	0.902
DIP2C	NBEAL1	0.902	0.066
PRICKLE1	ANKIB1	0.902
PRICKLE1	MOV10L1	0.902
PRICKLE1	NBEAL1	0.902
MOV10L1	NBEAL1	0.902
ANKIB1	NBEAL1	0.902	0.046
MOV10L1	ANKIB1	0.902
DIP2C	ANKIB1	0.902	0.102
DIP2C	MOV10L1	0.902
ANKIB1	CAPN15	0.902	0.094
TC2N	ANKIB1	0.902
MOV10L1	CAPN15	0.892
TC2N	DIP2C	0.768
TC2N	NBEAL1	0.768
NBEAL1	CAPN15	0.755	0.062
DIP2C	CAPN15	0.747	0.102
TC2N	CAPN15	0.715
NKD1	DACT1	0.415
MATCAP2	NKD1	0.415
RIMS4	RND2	0.415
PRICKLE1	RND2	0.415
DACT1	PRICKLE2	0.415
NKD1	PRICKLE1	0.415
ANKRD18A	CDCA7	0.415
NKD1	MERTK	0.415
RIMS4	ANKRD18A	0.415
RNF125	PRICKLE2	0.415
DIP2C	RNF125	0.415
PRICKLE1	RNF125	0.415
NKD1	SECISBP2	0.415
ANKRD18A	DIP2C	0.415
RIMS4	DIP2C	0.415
PRICKLE1	CDCA7	0.415
ANKRD18A	DACT1	0.415
RIMS4	RNF125	0.415
ANKRD18A	RND2	0.415
NKD1	CDCA7	0.415
CDCA7	PRICKLE2	0.415
ANKRD18A	RNF125	0.415
CDCA7	DACT1	0.415
CDCA7	RNF125	0.415
RNF125	MERTK	0.415
MATCAP2	PRICKLE2	0.415
ANKRD18A	PRICKLE1	0.415
MATCAP2	PRICKLE1	0.415
RNF125	SECISBP2	0.415
NKD1	PRICKLE2	0.415
DACT1	RND2	0.415
ANKRD18A	PRICKLE2	0.415
DACT1	MERTK	0.415
RIMS4	NKD1	0.415
DIP2C	CDCA7	0.415	0.09
PRICKLE1	SECISBP2	0.415
DIP2C	DACT1	0.415
PRICKLE2	SECISBP2	0.415
RIMS4	DACT1	0.415
RND2	PRICKLE2	0.415
RIMS4	CDCA7	0.415
PRICKLE1	PRICKLE2	0.415
MERTK	PRICKLE2	0.415
CDCA7	RND2	0.415
RNF125	RND2	0.415
DACT1	SECISBP2	0.415
RIMS4	PRICKLE1	0.415
NKD1	RND2	0.415
PRICKLE1	MERTK	0.415
DIP2C	NKD1	0.415
PRICKLE1	DACT1	0.415
NKD1	RNF125	0.415
ANKRD18A	NKD1	0.415
RNF125	DACT1	0.415
DIP2C	RND2	0.415
DIP2C	PRICKLE2	0.415
MATCAP2	RNF125	0.415
RIMS4	PRICKLE2	0.415
RNF125	CAPN15	0.364
PRICKLE2	CAPN15	0.364
NKD1	CAPN15	0.364
NKD1	ROBO1	0.278
ROBO1	PRICKLE2	0.278
ROBO1	RNF125	0.278
PRICKLE1	ROBO1	0.278
RIMS4	MERTK	0.274
RIMS4	SECISBP2	0.274
NRSN2	RNF125	0.274
CDCA7	SECISBP2	0.274	0.124
ANKRD18A	SECISBP2	0.274
ANKRD18A	MERTK	0.274
NKD1	NRSN2	0.274
PRICKLE1	NRSN2	0.274
MERTK	RND2	0.274
CDCA7	MERTK	0.274	0.082
DIP2C	MERTK	0.274	0.092
MATCAP2	DACT1	0.274
NRSN2	PRICKLE2	0.274
DIP2C	SECISBP2	0.274	0.144
RND2	SECISBP2	0.274
DACT1	CAPN15	0.229
ANKIB1	MERTK	0.214	0.126
ANKIB1	DACT1	0.214
MOV10L1	RND2	0.214
RNF125	NBEAL1	0.214
CDCA7	NBEAL1	0.214	0.06
ANKIB1	RNF125	0.214
ANKRD18A	MOV10L1	0.214
TC2N	NKD1	0.214
MOV10L1	SECISBP2	0.214
NBEAL1	PRICKLE2	0.214
ANKIB1	RND2	0.214
NBEAL1	DACT1	0.214
ANKRD18A	NBEAL1	0.214
ANKRD18A	ANKIB1	0.214
NBEAL1	RND2	0.214
TC2N	RNF125	0.214
NKD1	MOV10L1	0.214
NKD1	NBEAL1	0.214
RIMS4	NBEAL1	0.214
ANKIB1	SECISBP2	0.214	0.16
TC2N	PRICKLE2	0.214
RIMS4	MOV10L1	0.214
MOV10L1	PRICKLE2	0.214
MATCAP2	ANKIB1	0.214
ANKIB1	CDCA7	0.214	0.08
ANKIB1	PRICKLE2	0.214
RIMS4	ANKIB1	0.214
MOV10L1	RNF125	0.214
NKD1	ANKIB1	0.214
MOV10L1	CDCA7	0.214
MOV10L1	DACT1	0.214
MOV10L1	MERTK	0.214
MERTK	SECISBP2	0.21	0.116
ROBO1	ANKIB1	0.146	0.092
NBEAL1	MERTK	0.146	0.084
MATCAP2	MOV10L1	0.146
NBEAL1	SECISBP2	0.146	0.118
TC2N	DACT1	0.146
ANKIB1	NRSN2	0.146	0.08
ROBO1	DACT1	0.113
MATCAP2	ANKRD18A	0.113
MATCAP2	DIP2C	0.113
MATCAP2	CDCA7	0.113
NRSN2	DACT1	0.113
RIMS4	MATCAP2	0.113
ANKRD18A	ROBO1	0.095
RIMS4	ROBO1	0.095
ROBO1	CDCA7	0.095	0.104
ROBO1	RND2	0.095
DIP2C	ROBO1	0.095	0.138
MATCAP2	MERTK	0.095
MATCAP2	SECISBP2	0.095
ROBO1	CAPN15	0.095	0.092
ROBO1	NRSN2	0.087	0.094
ANKRD18A	CAPN15	0.083
RND2	CAPN15	0.083
CDCA7	CAPN15	0.083	0.062
RIMS4	CAPN15	0.083
MATCAP2	RND2	0.079
ROBO1	MERTK	0.079	0.07
NRSN2	CAPN15	0.078	0.082
ANKRD18A	NRSN2	0.078
CDCA7	NRSN2	0.078	0.052
ROBO1	SECISBP2	0.078	0.13
NRSN2	RND2	0.078
DIP2C	NRSN2	0.078	0.112
RIMS4	NRSN2	0.078
MATCAP2	NRSN2	0.076
MATCAP2	ROBO1	0.076
NRSN2	SECISBP2	0.076	0.084
NRSN2	MERTK	0.076	0.044
MATCAP2	CAPN15	0.07
MERTK	CAPN15	0.07	0.106
CAPN15	SECISBP2	0.07	0.172
MOV10L1	NRSN2	0.055
MATCAP2	NBEAL1	0.055
TC2N	RND2	0.055
TC2N	CDCA7	0.055
ROBO1	MOV10L1	0.055
ANKRD18A	TC2N	0.055
RIMS4	TC2N	0.055
ROBO1	NBEAL1	0.046	0.08
TC2N	SECISBP2	0.046
TC2N	MERTK	0.046
NRSN2	NBEAL1	0.043	0.062
MATCAP2	TC2N	0.043
TC2N	NRSN2	0.042
TC2N	ROBO1	0.042

Related Complexes

Genename	Complexes
NKD1	huMAP3_03785.1 huMAP3_05892.1 huMAP3_08831.1 huMAP3_11633.1
ROBO1	huMAP3_03785.1 huMAP3_05824.1 huMAP3_08831.1 huMAP3_12575.1 huMAP3_14116.1 huMAP3_14269.1 huMAP3_14544.1
ANKRD18A	huMAP3_00869.1 huMAP3_08831.1 huMAP3_09262.1 huMAP3_11633.1
RNF125	huMAP3_03785.1 huMAP3_06476.1 huMAP3_08831.1 huMAP3_11633.1
RND2	huMAP3_03785.1 huMAP3_05993.1 huMAP3_08831.1 huMAP3_12735.1 huMAP3_14249.1
MOV10L1	huMAP3_03785.1 huMAP3_07067.1 huMAP3_08831.1 huMAP3_11633.1 huMAP3_11729.1
MERTK	huMAP3_03785.1 huMAP3_05820.1 huMAP3_08831.1 huMAP3_11349.1 huMAP3_11633.1 huMAP3_14792.1
DIP2C	huMAP3_03481.1 huMAP3_05647.1 huMAP3_08199.1 huMAP3_08289.1 huMAP3_08432.1 huMAP3_08831.1 huMAP3_08874.1 huMAP3_09163.1 huMAP3_09657.1 huMAP3_09823.1 huMAP3_10957.1 huMAP3_11633.1 huMAP3_11729.1
RIMS4	huMAP3_00014.1 huMAP3_06785.1 huMAP3_08831.1 huMAP3_09293.1 huMAP3_10529.1 huMAP3_11633.1 huMAP3_14564.1
CDCA7	huMAP3_03785.1 huMAP3_06574.1 huMAP3_08831.1 huMAP3_12561.1
NBEAL1	huMAP3_03785.1 huMAP3_05522.1 huMAP3_05820.1 huMAP3_05824.1 huMAP3_05892.1 huMAP3_05993.1 huMAP3_06476.1 huMAP3_06574.1 huMAP3_06816.1 huMAP3_07067.1 huMAP3_07322.1 huMAP3_08831.1 huMAP3_11633.1 huMAP3_11729.1
DACT1	huMAP3_03785.1 huMAP3_07322.1 huMAP3_08831.1 huMAP3_11633.1
PRICKLE2	huMAP3_03785.1 huMAP3_06816.1 huMAP3_08831.1 huMAP3_11633.1
CAPN15	huMAP3_03785.1 huMAP3_05522.1 huMAP3_05820.1 huMAP3_05824.1 huMAP3_05892.1 huMAP3_05993.1 huMAP3_06476.1 huMAP3_06574.1 huMAP3_06816.1 huMAP3_07067.1 huMAP3_07322.1 huMAP3_08831.1 huMAP3_11633.1 huMAP3_11729.1 huMAP3_11882.1
PRICKLE1	huMAP3_03785.1 huMAP3_05522.1 huMAP3_05820.1 huMAP3_05824.1 huMAP3_05892.1 huMAP3_05993.1 huMAP3_06476.1 huMAP3_06574.1 huMAP3_06816.1 huMAP3_07067.1 huMAP3_07322.1 huMAP3_08831.1 huMAP3_11633.1 huMAP3_11729.1
ANKIB1	huMAP3_03785.1 huMAP3_05522.1 huMAP3_05820.1 huMAP3_05824.1 huMAP3_05892.1 huMAP3_05993.1 huMAP3_06476.1 huMAP3_06574.1 huMAP3_06816.1 huMAP3_07067.1 huMAP3_07322.1 huMAP3_08831.1 huMAP3_11633.1 huMAP3_11729.1
MATCAP2	huMAP3_00307.1 huMAP3_01799.1 huMAP3_08831.1 huMAP3_11310.1
NRSN2	huMAP3_03785.1 huMAP3_05522.1 huMAP3_08831.1 huMAP3_12704.1
KCNE3	huMAP3_03785.1 huMAP3_05522.1 huMAP3_05820.1 huMAP3_05824.1 huMAP3_05892.1 huMAP3_05993.1 huMAP3_06476.1 huMAP3_06574.1 huMAP3_06816.1 huMAP3_07067.1 huMAP3_07322.1 huMAP3_08831.1 huMAP3_11633.1
TC2N	huMAP3_02061.1 huMAP3_07534.1 huMAP3_08831.1 huMAP3_09729.1 huMAP3_10654.1 huMAP3_11633.1 huMAP3_11729.1 huMAP3_12538.1 huMAP3_13022.1 huMAP3_15185.1
SECISBP2	huMAP3_05025.1 huMAP3_06597.1 huMAP3_07241.1 huMAP3_08104.1 huMAP3_08831.1 huMAP3_13523.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_08831.1

Complex Portal: CPX-17114