hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_08847.1

Complex Portal: CPX-15697

Confidence: High

Genename	Protein Name	Uniprot Annotation Score	Links
MPDU1	Mannose-P-dolichol utilization defect 1 protein (Suppressor of Lec15 and Lec35 glycosylation mutation homolog) (SL15)	4	UniProt NCBI
NIPA1	Magnesium transporter NIPA1 (Non-imprinted in Prader-Willi/Angelman syndrome region protein 1) (Spastic paraplegia 6 protein)	5	UniProt NCBI
SLC18B1	MFS-type transporter SLC18B1 (Solute carrier family 18 member B1) (Vesicular polyamine transporter) (VPAT)	5	UniProt NCBI
SRR	Serine racemase (EC 5.1.1.18) (D-serine ammonia-lyase) (D-serine dehydratase) (EC 4.3.1.18) (L-serine ammonia-lyase) (L-serine dehydratase) (EC 4.3.1.17)	5	UniProt NCBI
PHGDH	D-3-phosphoglycerate dehydrogenase (3-PGDH) (EC 1.1.1.95) (2-oxoglutarate reductase) (EC 1.1.1.399) (Malate dehydrogenase) (EC 1.1.1.37)	5	UniProt NCBI
TMEM177	Transmembrane protein 177	3	UniProt NCBI
COA6	Cytochrome c oxidase assembly factor 6 homolog	5	UniProt NCBI
SEC61A2	Protein transport protein Sec61 subunit alpha isoform 2 (Sec61 alpha-2)	3	UniProt NCBI
ADCK1	AarF domain-containing protein kinase 1 (EC 2.7.-.-)	5	UniProt NCBI
BTAF1	TATA-binding protein-associated factor 172 (EC 3.6.4.-) (ATP-dependent helicase BTAF1) (B-TFIID transcription factor-associated 170 kDa subunit) (TAF(II)170) (TBP-associated factor 172) (TAF-172)	5	UniProt NCBI
DOP1B	Protein dopey-2	5	UniProt NCBI
MFSD4A	Major facilitator superfamily domain-containing protein 4A (Major facilitator superfamily domain-containing protein 4)	3	UniProt NCBI
STARD3	StAR-related lipid transfer protein 3 (Metastatic lymph node gene 64 protein) (MLN 64) (Protein CAB1) (START domain-containing protein 3) (StARD3)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
WP:WP4688	0.00178736081944	0.153846153846	PHGDH SRR	Serine metabolism
REAC:R-HSA-977347	0.00418027557771	0.153846153846	PHGDH SRR	Serine biosynthesis
KEGG:00260	0.0217216276183	0.153846153846	PHGDH SRR	Glycine, serine and threonine metabolism
WP:WP4922	0.0416894057602	0.153846153846	TMEM177 COA6	Mitochondrial complex IV assembly

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
DOP1B	MFSD4A	0.996
SRR	MFSD4A	0.996
NIPA1	MFSD4A	0.994
ADCK1	MFSD4A	0.993
SLC18B1	MFSD4A	0.988
TMEM177	MFSD4A	0.988
COA6	MFSD4A	0.979
PHGDH	MFSD4A	0.975
BTAF1	MFSD4A	0.967
SEC61A2	MFSD4A	0.964
MFSD4A	MPDU1	0.963		structurally_consistent (dimer)
MFSD4A	STARD3	0.959		structurally_consistent (dimer)
ADCK1	STARD3	0.954	0.14
TMEM177	STARD3	0.941	0.038
ADCK1	MPDU1	0.931	0.084
SLC18B1	STARD3	0.927	0.046
ADCK1	TMEM177	0.881	0.13
SRR	TMEM177	0.835	0.032
STARD3	MPDU1	0.824	0.032	structurally_consistent (Q8N468)
SRR	ADCK1	0.82	0.056
NIPA1	SLC18B1	0.797	0.152
SEC61A2	BTAF1	0.764	0.054
ADCK1	SEC61A2	0.755	0.044
SRR	PHGDH	0.671	0.104
ADCK1	BTAF1	0.653	0.058
SEC61A2	STARD3	0.64	0.104
NIPA1	DOP1B	0.634	0.048
SRR	NIPA1	0.634	0.088
TMEM177	DOP1B	0.634	0.032
NIPA1	STARD3	0.633	0.086
SEC61A2	NIPA1	0.633	0.142
BTAF1	NIPA1	0.632	0.042
TMEM177	SEC61A2	0.61	0.096
ADCK1	DOP1B	0.604	0.066
ADCK1	SLC18B1	0.592
SRR	MPDU1	0.56	0.044
TMEM177	BTAF1	0.475	0.06
SRR	SLC18B1	0.443	0.054
ADCK1	COA6	0.416	0.092
TMEM177	NIPA1	0.392	0.11
SEC61A2	DOP1B	0.374	0.034
ADCK1	NIPA1	0.363	0.144
DOP1B	STARD3	0.348	0.06
BTAF1	MPDU1	0.346	0.016
SEC61A2	MPDU1	0.32	0.104
COA6	MPDU1	0.311	0.154
SEC61A2	SLC18B1	0.296	0.108
PHGDH	SLC18B1	0.291	0.128
PHGDH	DOP1B	0.282	0.042
BTAF1	STARD3	0.278	0.042
DOP1B	MPDU1	0.268	0.032
BTAF1	DOP1B	0.253	0.044
ADCK1	PHGDH	0.251	0.118
SLC18B1	DOP1B	0.249	0.07
TMEM177	SLC18B1	0.246	0.04
COA6	SLC18B1	0.246	0.044
BTAF1	SLC18B1	0.242	0.066
SRR	STARD3	0.187	0.054
COA6	NIPA1	0.18	0.058
SRR	DOP1B	0.153	0.07
SRR	BTAF1	0.153	0.03
COA6	DOP1B	0.144	0.01
SLC18B1	MPDU1	0.14	0.094
PHGDH	NIPA1	0.131	0.116
NIPA1	MPDU1	0.127	0.1
BTAF1	PHGDH	0.127	0.074
TMEM177	COA6	0.108	0.08
TMEM177	MPDU1	0.101	0.154
COA6	STARD3	0.086	0.02
SRR	SEC61A2	0.076	0.068
BTAF1	COA6	0.069	0.024
PHGDH	COA6	0.062	0.0783642081189
SRR	COA6	0.045	0.012
SEC61A2	COA6	0.039	0.0846666666667
TMEM177	PHGDH	0.011	0.217090909091
PHGDH	MPDU1	0.008	0.0681823899371
PHGDH	STARD3	0.007	0.088
SEC61A2	PHGDH	0.003	0.326

Related Complexes

Genename	Complexes
MPDU1	huMAP3_07668.1 huMAP3_08847.1 huMAP3_09805.1 huMAP3_09862.1
NIPA1	huMAP3_03654.1 huMAP3_03967.1 huMAP3_07539.1 huMAP3_07785.1 huMAP3_08847.1 huMAP3_08886.1 huMAP3_09862.1 huMAP3_11067.1 huMAP3_13473.1 huMAP3_15269.1
SLC18B1	huMAP3_03654.1 huMAP3_05018.1 huMAP3_05364.1 huMAP3_05469.1 huMAP3_07205.1 huMAP3_07913.1 huMAP3_08253.1 huMAP3_08847.1 huMAP3_09862.1 huMAP3_10990.1 huMAP3_11067.1
SRR	huMAP3_00760.1 huMAP3_08847.1 huMAP3_09862.1
PHGDH	huMAP3_01822.1 huMAP3_04429.1 huMAP3_08847.1 huMAP3_09862.1 huMAP3_09902.1 huMAP3_10033.1 huMAP3_10164.1 huMAP3_12600.1 huMAP3_14360.1
TMEM177	huMAP3_00871.1 huMAP3_03654.1 huMAP3_08847.1 huMAP3_08910.1 huMAP3_09161.1 huMAP3_09862.1 huMAP3_10794.1 huMAP3_11067.1
COA6	huMAP3_03288.1 huMAP3_03654.1 huMAP3_05906.1 huMAP3_07539.1 huMAP3_07974.1 huMAP3_08847.1 huMAP3_09862.1 huMAP3_11067.1 huMAP3_14101.1
SEC61A2	huMAP3_00939.1 huMAP3_06447.1 huMAP3_08119.1 huMAP3_08847.1 huMAP3_09310.1 huMAP3_09862.1
ADCK1	huMAP3_00871.1 huMAP3_03654.1 huMAP3_06302.1 huMAP3_07539.1 huMAP3_08847.1 huMAP3_09862.1 huMAP3_10794.1 huMAP3_11067.1
BTAF1	huMAP3_01352.1 huMAP3_06077.1 huMAP3_07539.1 huMAP3_08298.1 huMAP3_08847.1 huMAP3_08936.1 huMAP3_09053.1 huMAP3_09114.1 huMAP3_09862.1 huMAP3_10202.1 huMAP3_10287.1 huMAP3_11067.1 huMAP3_11232.1
DOP1B	huMAP3_03654.1 huMAP3_03685.1 huMAP3_03754.1 huMAP3_05476.1 huMAP3_07234.1 huMAP3_08511.1 huMAP3_08674.1 huMAP3_08847.1 huMAP3_09862.1 huMAP3_11067.1
MFSD4A	huMAP3_03654.1 huMAP3_07539.1 huMAP3_08847.1 huMAP3_09862.1 huMAP3_11067.1 huMAP3_13473.1 huMAP3_13945.1
STARD3	huMAP3_03654.1 huMAP3_06302.1 huMAP3_07539.1 huMAP3_08847.1 huMAP3_09862.1 huMAP3_11067.1 huMAP3_14172.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_08847.1

Complex Portal: CPX-15697