hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_08848.1

Complex Portal: CPX-18052

Confidence: High

Genename	Protein Name	Uniprot Annotation Score	Links
MACROH2A2	Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2)	5	UniProt NCBI
CDYL	Chromodomain Y-like protein (CDY-like) (Crotonyl-CoA hydratase) (EC 4.2.1.-)	5	UniProt NCBI
ARID5B	AT-rich interactive domain-containing protein 5B (ARID domain-containing protein 5B) (MRF1-like protein) (Modulator recognition factor 2) (MRF-2)	5	UniProt NCBI
ANP32E	Acidic leucine-rich nuclear phosphoprotein 32 family member E (LANP-like protein) (LANP-L)	5	UniProt NCBI
CRAMP1	Protein cramped-like (Cramped chromatin regulator homolog 1) (Hematological and neurological expressed 1-like protein)	3	UniProt NCBI
GON4L	GON-4-like protein (GON-4 homolog)	4	UniProt NCBI
C16orf87	UPF0547 protein C16orf87	3	UniProt NCBI
MIER1	Mesoderm induction early response protein 1 (Early response 1) (Er1) (Mi-er1) (hMi-er1)	5	UniProt NCBI
MCM6	DNA replication licensing factor MCM6 (EC 3.6.4.12) (p105MCM)	5	UniProt NCBI
PPM1G	Protein phosphatase 1G (EC 3.1.3.16) (Protein phosphatase 1C) (Protein phosphatase 2C isoform gamma) (PP2C-gamma) (Protein phosphatase magnesium-dependent 1 gamma)	5	UniProt NCBI
H2AJ	Histone H2A.J (H2a/j)	4	UniProt NCBI
BAHD1	Bromo adjacent homology domain-containing 1 protein (BAH domain-containing protein 1)	5	UniProt NCBI
MIER3	Mesoderm induction early response protein 3 (Mi-er3)	5	UniProt NCBI
MCM4	DNA replication licensing factor MCM4 (EC 3.6.4.12) (CDC21 homolog) (P1-CDC21)	5	UniProt NCBI
H2BC1	Histone H2B type 1-A (Histone H2B, testis) (TSH2B.1) (hTSH2B) (Testis-specific histone H2B)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
KEGG:05322	0.00748758149237	0.214285714286	H2BC1 MACROH2A2 H2AJ	Systemic lupus erythematosus
KEGG:04613	0.0193604961214	0.214285714286	H2BC1 MACROH2A2 H2AJ	Neutrophil extracellular trap formation
KEGG:05034	0.0193604961214	0.214285714286	H2BC1 MACROH2A2 H2AJ	Alcoholism
WP:WP4553	0.0484579411248	0.142857142857	MACROH2A2 H2AJ	FBXL10 enhancement of MAP ERK signaling in diffuse large B cell lymphoma
CORUM:2791	0.0499958217778	0.0714285714286	MCM6	MCM4-MCM6-MCM7 complex

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
MCM6	MCM4	1.0	0.986	structurally_consistent (dimer)
GON4L	CRAMP1	1.0	0.16
ARID5B	C16orf87	1.0	0.068
MIER3	C16orf87	0.999	0.07
MIER1	C16orf87	0.999	0.17
H2BC1	C16orf87	0.998	0.17
MIER1	CDYL	0.998	0.05
MIER3	MIER1	0.998	0.138
H2BC1	MACROH2A2	0.998	0.266	structurally_consistent (dimer)
H2BC1	MIER3	0.998	0.16	structurally_consistent (dimer)
ARID5B	MIER1	0.997	0.106
H2BC1	GON4L	0.997	0.207333333333
PPM1G	MACROH2A2	0.997	0.058	mutually_exclusive (Q8N257)
H2BC1	CRAMP1	0.997	0.132
H2BC1	BAHD1	0.997
H2BC1	ARID5B	0.997	0.24
H2BC1	MIER1	0.996	0.34
H2BC1	MCM6	0.996	0.29
H2BC1	ANP32E	0.996	0.234	mutually_exclusive (P0C0S5) structurally_consistent (dimer)
MIER3	CDYL	0.995	0.07
H2BC1	PPM1G	0.995	0.55	mutually_exclusive (P0C0S5)
H2BC1	CDYL	0.991	0.262
H2BC1	MCM4	0.99	0.368
ARID5B	MIER3	0.988	0.14
MIER3	BAHD1	0.983
ARID5B	MCM4	0.982	0.072
CDYL	C16orf87	0.979	0.074
ARID5B	MCM6	0.975	0.068
BAHD1	CDYL	0.967
ARID5B	BAHD1	0.966
BAHD1	C16orf87	0.966
MCM4	MACROH2A2	0.966	0.204
BAHD1	MIER1	0.966
GON4L	MIER1	0.962	0.102
MCM6	MACROH2A2	0.959	0.33
CRAMP1	H2AJ	0.959	0.106
GON4L	MIER3	0.958	0.202
GON4L	CDYL	0.957	0.102
MIER1	ANP32E	0.957	0.118
GON4L	H2AJ	0.955	0.176
ARID5B	CDYL	0.951	0.08
ARID5B	GON4L	0.95	0.164
GON4L	ANP32E	0.949	0.166
GON4L	C16orf87	0.949	0.14
MIER3	CRAMP1	0.944	0.148
MCM4	GON4L	0.943	0.154
MIER3	PPM1G	0.941	0.074
BAHD1	ANP32E	0.938
MCM6	GON4L	0.938	0.184
MCM6	C16orf87	0.933	0.096
C16orf87	ANP32E	0.931	0.11	mutually_exclusive (Q92993)
MCM4	MIER3	0.929	0.062
MCM6	MIER3	0.929	0.044
MIER3	ANP32E	0.923	0.084
MCM4	C16orf87	0.923	0.078
MIER1	CRAMP1	0.918	0.094
GON4L	PPM1G	0.911	0.166
PPM1G	MIER1	0.908	0.088
ARID5B	MACROH2A2	0.907	0.06
ARID5B	ANP32E	0.904	0.098
MCM4	MIER1	0.899	0.1
MCM4	CDYL	0.891	0.052
CDYL	ANP32E	0.882	0.038
CDYL	CRAMP1	0.86	0.034
PPM1G	BAHD1	0.858
PPM1G	C16orf87	0.85	0.102
MIER1	H2AJ	0.843	0.146
MACROH2A2	C16orf87	0.825	0.044
MACROH2A2	BAHD1	0.815
MCM6	MIER1	0.785	0.082
GON4L	BAHD1	0.776
PPM1G	H2AJ	0.742	0.252
CRAMP1	ANP32E	0.735	0.08
MIER3	H2AJ	0.732	0.133333333333
ARID5B	PPM1G	0.732	0.108
MCM6	CDYL	0.714	0.05
MACROH2A2	ANP32E	0.679	0.072	mutually_exclusive (Q8N257)
MCM4	CRAMP1	0.666	0.06
PPM1G	CDYL	0.648	0.072
PPM1G	CRAMP1	0.573	0.102
MACROH2A2	MIER1	0.566	0.048
MACROH2A2	CDYL	0.546	0.024
C16orf87	CRAMP1	0.537	0.068
MIER3	MACROH2A2	0.525	0.06	mutually_exclusive (Q96A08)
GON4L	MACROH2A2	0.525	0.068
MCM6	BAHD1	0.502
MCM4	BAHD1	0.435
MCM6	ANP32E	0.421	0.206
MACROH2A2	CRAMP1	0.402	0.068
BAHD1	CRAMP1	0.353
ARID5B	CRAMP1	0.351	0.142
MCM4	ANP32E	0.307	0.214
MCM6	CRAMP1	0.277	0.088
PPM1G	ANP32E	0.241	0.266
CDYL	H2AJ	0.13	0.098
MCM4	PPM1G	0.104	0.284
MCM6	H2AJ	0.087	0.252
MCM4	H2AJ	0.055	0.302
MCM6	PPM1G	0.041	0.302
H2BC1	H2AJ	0.008	0.282769230769

Related Complexes

Genename	Complexes
MACROH2A2	huMAP3_02743.1 huMAP3_08848.1 huMAP3_09387.1 huMAP3_09466.1 huMAP3_10592.1 huMAP3_10862.1
CDYL	huMAP3_02906.1 huMAP3_03774.1 huMAP3_06957.1 huMAP3_07203.1 huMAP3_08848.1 huMAP3_09466.1 huMAP3_09728.1 huMAP3_10862.1 huMAP3_14306.1
ARID5B	huMAP3_00136.1 huMAP3_01124.1 huMAP3_06233.1 huMAP3_07203.1 huMAP3_08848.1 huMAP3_09466.1 huMAP3_09728.1 huMAP3_10862.1 huMAP3_14306.1
ANP32E	huMAP3_04650.1 huMAP3_06556.1 huMAP3_08848.1 huMAP3_09466.1 huMAP3_09677.1 huMAP3_10481.1 huMAP3_10862.1 huMAP3_14306.1
CRAMP1	huMAP3_03510.1 huMAP3_08848.1 huMAP3_09466.1 huMAP3_09682.1 huMAP3_10862.1 huMAP3_14306.1
GON4L	huMAP3_01124.1 huMAP3_03510.1 huMAP3_06233.1 huMAP3_08848.1 huMAP3_09466.1 huMAP3_09682.1 huMAP3_09728.1 huMAP3_10862.1 huMAP3_14306.1
C16orf87	huMAP3_02906.1 huMAP3_06600.1 huMAP3_06957.1 huMAP3_08848.1 huMAP3_09466.1 huMAP3_09728.1 huMAP3_10862.1 huMAP3_14306.1
MIER1	huMAP3_02906.1 huMAP3_06957.1 huMAP3_07203.1 huMAP3_08848.1 huMAP3_09466.1 huMAP3_09728.1 huMAP3_10862.1 huMAP3_14306.1
MCM6	huMAP3_00154.1 huMAP3_02602.1 huMAP3_05529.1 huMAP3_06061.1 huMAP3_07113.1 huMAP3_08554.1 huMAP3_08848.1 huMAP3_09466.1 huMAP3_09860.1 huMAP3_10862.1 huMAP3_11119.1 huMAP3_11832.1 huMAP3_12180.1 huMAP3_14306.1 huMAP3_14758.1
PPM1G	huMAP3_02743.1 huMAP3_08848.1 huMAP3_09387.1 huMAP3_09466.1 huMAP3_10592.1 huMAP3_10862.1 huMAP3_14306.1
H2AJ	huMAP3_07377.1 huMAP3_07727.1 huMAP3_08848.1 huMAP3_09466.1 huMAP3_09682.1 huMAP3_10862.1 huMAP3_12980.1 huMAP3_12998.1
BAHD1	huMAP3_02787.1 huMAP3_02906.1 huMAP3_04634.1 huMAP3_06233.1 huMAP3_06556.1 huMAP3_07203.1 huMAP3_08848.1 huMAP3_09466.1 huMAP3_09677.1 huMAP3_09728.1 huMAP3_10481.1 huMAP3_10862.1 huMAP3_14306.1
MIER3	huMAP3_01124.1 huMAP3_03774.1 huMAP3_06233.1 huMAP3_07203.1 huMAP3_08848.1 huMAP3_09466.1 huMAP3_09728.1 huMAP3_10862.1 huMAP3_14306.1
MCM4	huMAP3_00154.1 huMAP3_02602.1 huMAP3_05529.1 huMAP3_06061.1 huMAP3_07113.1 huMAP3_08554.1 huMAP3_08848.1 huMAP3_09466.1 huMAP3_09860.1 huMAP3_10862.1 huMAP3_11119.1 huMAP3_11832.1 huMAP3_12180.1 huMAP3_14306.1 huMAP3_14758.1
H2BC1	huMAP3_00136.1 huMAP3_04634.1 huMAP3_06556.1 huMAP3_07203.1 huMAP3_08848.1 huMAP3_09466.1 huMAP3_09677.1 huMAP3_10481.1 huMAP3_10862.1 huMAP3_14306.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_08848.1

Complex Portal: CPX-18052