hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08862.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CALHM4 | Calcium homeostasis modulator protein 4 (Protein FAM26D) | 3 | UniProt NCBI |
| CRYBG1 | Beta/gamma crystallin domain-containing protein 1 (Absent in melanoma 1 protein) | 4 | UniProt NCBI |
| IL31RA | Interleukin-31 receptor subunit alpha (IL-31 receptor subunit alpha) (IL-31R subunit alpha) (IL-31R-alpha) (IL-31RA) (Cytokine receptor-like 3) (GLM-R) (hGLM-R) (Gp130-like monocyte receptor) (Gp130-like receptor) (ZcytoR17) | 5 | UniProt NCBI |
| SELENBP1 | Methanethiol oxidase (MTO) (EC 1.8.3.4) (56 kDa selenium-binding protein) (SBP56) (SP56) (Selenium-binding protein 1) | 5 | UniProt NCBI |
| PLCD1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 (EC 3.1.4.11) (Phosphoinositide phospholipase C-delta-1) (Phospholipase C-III) (PLC-III) (Phospholipase C-delta-1) (PLC-delta-1) | 5 | UniProt NCBI |
| SPINK5 | Serine protease inhibitor Kazal-type 5 (Lympho-epithelial Kazal-type-related inhibitor) (LEKTI) [Cleaved into: Hemofiltrate peptide HF6478; Hemofiltrate peptide HF7665] | 5 | UniProt NCBI |
| PADI3 | Protein-arginine deiminase type-3 (EC 3.5.3.15) (Peptidylarginine deiminase III) (Protein-arginine deiminase type III) | 5 | UniProt NCBI |
| HEPHL1 | Ferroxidase HEPHL1 (EC 1.16.3.1) (Hephaestin-like protein 1) | 5 | UniProt NCBI |
| OR51E2 | Olfactory receptor 51E2 (HPRAJ) (Olfactory receptor OR11-16) (Prostate-specific G-protein coupled receptor) | 5 | UniProt NCBI |
| PYHIN1 | Pyrin and HIN domain-containing protein 1 (Interferon-inducible protein X) | 5 | UniProt NCBI |
| LYG2 | Lysozyme g-like protein 2 (EC 3.2.1.-) | 4 | UniProt NCBI |
| DHRS12 | Dehydrogenase/reductase SDR family member 12 (EC 1.1.-.-) (Short-chain dehydrogenase/reductase family 40C member 1) (Protein SDR40C1) | 3 | UniProt NCBI |
| DSG4 | Desmoglein-4 (Cadherin family member 13) | 5 | UniProt NCBI |
| S100A3 | Protein S100-A3 (Protein S-100E) (S100 calcium-binding protein A3) | 5 | UniProt NCBI |
| LRRC15 | Leucine-rich repeat-containing protein 15 (Leucine-rich repeat protein induced by beta-amyloid homolog) (hLib) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0003328 | 1.58107937884e-05 | 0.307692307692 | SPINK5 DSG4 PADI3 HEPHL1 | Abnormal hairshaft morphology |
| HP:0003777 | 0.0499631138006 | 0.153846153846 | HEPHL1 DSG4 | Pili torti |
| HP:0009886 | 0.0499631138006 | 0.153846153846 | SPINK5 HEPHL1 | Trichorrhexis nodosa |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| S100A3 | DSG4 | 0.992 | |
| SELENBP1 | LYG2 | 0.989 | |
| PYHIN1 | SPINK5 | 0.988 | |
| S100A3 | PADI3 | 0.987 | |
| CRYBG1 | PADI3 | 0.987 | |
| PLCD1 | PADI3 | 0.986 | |
| CALHM4 | CRYBG1 | 0.986 | |
| SELENBP1 | PADI3 | 0.984 | |
| CALHM4 | IL31RA | 0.984 | |
| S100A3 | LRRC15 | 0.983 | |
| HEPHL1 | CRYBG1 | 0.979 | |
| SELENBP1 | DSG4 | 0.979 | |
| S100A3 | CRYBG1 | 0.978 | 0.056 |
| DHRS12 | HEPHL1 | 0.978 | |
| LRRC15 | CALHM4 | 0.978 | |
| LRRC15 | LYG2 | 0.978 | |
| CRYBG1 | LYG2 | 0.978 | |
| PLCD1 | IL31RA | 0.977 | |
| PLCD1 | DHRS12 | 0.977 | |
| OR51E2 | S100A3 | 0.976 | |
| SELENBP1 | S100A3 | 0.976 | 0.034 |
| S100A3 | IL31RA | 0.975 | |
| S100A3 | CALHM4 | 0.975 | |
| SELENBP1 | CALHM4 | 0.975 | |
| PLCD1 | LYG2 | 0.975 | |
| PLCD1 | HEPHL1 | 0.975 | |
| PLCD1 | S100A3 | 0.975 | 0.046 |
| SELENBP1 | PLCD1 | 0.974 | 0.076 |
| DHRS12 | S100A3 | 0.974 | |
| DHRS12 | CALHM4 | 0.974 | |
| LRRC15 | IL31RA | 0.973 | |
| PLCD1 | CALHM4 | 0.973 | |
| PLCD1 | LRRC15 | 0.972 | |
| IL31RA | DSG4 | 0.972 | |
| S100A3 | LYG2 | 0.971 | |
| S100A3 | HEPHL1 | 0.969 | |
| HEPHL1 | CALHM4 | 0.969 | |
| HEPHL1 | DSG4 | 0.969 | |
| CALHM4 | DSG4 | 0.968 | |
| HEPHL1 | LYG2 | 0.968 | |
| LYG2 | DSG4 | 0.967 | |
| PLCD1 | CRYBG1 | 0.966 | 0.06 |
| SELENBP1 | LRRC15 | 0.965 | |
| S100A3 | SPINK5 | 0.965 | |
| HEPHL1 | IL31RA | 0.965 | |
| CALHM4 | LYG2 | 0.964 | |
| LYG2 | IL31RA | 0.964 | |
| LYG2 | PADI3 | 0.963 | |
| DSG4 | SPINK5 | 0.962 | |
| PLCD1 | DSG4 | 0.958 | |
| HEPHL1 | PADI3 | 0.958 | |
| LRRC15 | SPINK5 | 0.957 | |
| PYHIN1 | PADI3 | 0.954 | |
| LRRC15 | PADI3 | 0.953 | |
| HEPHL1 | SPINK5 | 0.951 | |
| CALHM4 | PADI3 | 0.95 | |
| SPINK5 | PADI3 | 0.949 | |
| SELENBP1 | HEPHL1 | 0.94 | |
| LRRC15 | HEPHL1 | 0.937 | |
| PLCD1 | SPINK5 | 0.937 | |
| LYG2 | SPINK5 | 0.936 | |
| PYHIN1 | DSG4 | 0.933 | |
| DHRS12 | DSG4 | 0.927 | |
| LRRC15 | DSG4 | 0.926 | |
| PYHIN1 | CALHM4 | 0.921 | |
| OR51E2 | DSG4 | 0.921 | |
| DSG4 | PADI3 | 0.916 | |
| CRYBG1 | DSG4 | 0.913 | |
| OR51E2 | LRRC15 | 0.902 | |
| CALHM4 | SPINK5 | 0.9 | |
| LRRC15 | CRYBG1 | 0.895 | |
| PYHIN1 | S100A3 | 0.887 | |
| PYHIN1 | LRRC15 | 0.859 | |
| PYHIN1 | LYG2 | 0.832 | |
| SELENBP1 | CRYBG1 | 0.817 | 0.07 |
| SELENBP1 | IL31RA | 0.814 | |
| DHRS12 | LRRC15 | 0.801 | |
| OR51E2 | CALHM4 | 0.722 | |
| CRYBG1 | IL31RA | 0.707 | |
| CRYBG1 | SPINK5 | 0.69 | |
| PYHIN1 | CRYBG1 | 0.58 | |
| OR51E2 | HEPHL1 | 0.571 | |
| IL31RA | PADI3 | 0.543 | |
| PYHIN1 | HEPHL1 | 0.505 | |
| PYHIN1 | PLCD1 | 0.5 | |
| SELENBP1 | SPINK5 | 0.43 |
Related Complexes