hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08868.1
Complex Portal: CPX-11770
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CHCHD3 | MICOS complex subunit MIC19 (Coiled-coil-helix-coiled-coil-helix domain-containing protein 3) | 5 | UniProt NCBI |
| TFRC | Transferrin receptor protein 1 (TR) (TfR) (TfR1) (Trfr) (T9) (p90) (CD antigen CD71) [Cleaved into: Transferrin receptor protein 1, serum form (sTfR)] | 5 | UniProt NCBI |
| ABCD3 | ATP-binding cassette sub-family D member 3 (EC 3.1.2.-) (EC 7.6.2.-) (70 kDa peroxisomal membrane protein) (PMP70) | 5 | UniProt NCBI |
| CHSY1 | Chondroitin sulfate synthase 1 (EC 2.4.1.175) (EC 2.4.1.226) (Chondroitin glucuronyltransferase 1) (Chondroitin synthase 1) (ChSy-1) (Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1) (N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1) (N-acetylgalactosaminyltransferase 1) | 5 | UniProt NCBI |
| MCU | Calcium uniporter protein, mitochondrial (HsMCU) (Coiled-coil domain-containing protein 109A) | 5 | UniProt NCBI |
| DNAJC11 | DnaJ homolog subfamily C member 11 | 5 | UniProt NCBI |
| KIDINS220 | Kinase D-interacting substrate of 220 kDa (Ankyrin repeat-rich membrane-spanning protein) | 5 | UniProt NCBI |
| RNF185 | E3 ubiquitin-protein ligase RNF185 (EC 2.3.2.27) (RING finger protein 185) | 5 | UniProt NCBI |
| DHRS7B | Dehydrogenase/reductase SDR family member 7B (EC 1.1.-.-) (Short-chain dehydrogenase/reductase family 32C member 1) (Protein SDR32C1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6249 | 0.00107416462378 | 0.25 | CHCHD3 DNAJC11 | MIB complex |
| REAC:R-HSA-8949613 | 0.0240813966337 | 0.25 | CHCHD3 DNAJC11 | Cristae formation |
| REAC:R-HSA-9696273 | 0.0367988237757 | 0.25 | TFRC KIDINS220 | RND1 GTPase cycle |
| REAC:R-HSA-9696270 | 0.0409204105231 | 0.25 | TFRC KIDINS220 | RND2 GTPase cycle |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RNF185 | DHRS7B | 0.994 | 0.162 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CHCHD3 | DNAJC11 | 0.992 | 0.662 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM hein () boldt_WMM | |
| MCU | DHRS7B | 0.991 | 0.05 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| RNF185 | ABCD3 | 0.99 | 0.146 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| ABCD3 | MCU | 0.988 | 0.214 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only | |
| DNAJC11 | DHRS7B | 0.987 | 0.046 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| CHCHD3 | ABCD3 | 0.987 | 0.162 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM bioplex3_HCT116 gupta_WMM boldt_WMM WMM_only | |
| ABCD3 | DHRS7B | 0.985 | 0.054 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM WMM_only | |
| MCU | DNAJC11 | 0.98 | 0.23 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only boldt_WMM | |
| ABCD3 | DNAJC11 | 0.979 | 0.144 | hein_WMM bioplex () bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM boldt_WMM | |
| CHSY1 | DNAJC11 | 0.978 | 0.1 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| CHSY1 | ABCD3 | 0.977 | 0.142 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| TFRC | ABCD3 | 0.976 | 0.178 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM WMM_only | |
| CHCHD3 | KIDINS220 | 0.969 | 0.07 | hein_WMM bioplex_WMM bioplex3_WMM gupta_WMM WMM_only | |
| TFRC | KIDINS220 | 0.968 | 0.204333333333 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| CHCHD3 | DHRS7B | 0.966 | 0.088 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only | |
| CHSY1 | DHRS7B | 0.965 | 0.076 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| RNF185 | CHSY1 | 0.958 | 0.104 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| RNF185 | MCU | 0.95 | 0.122 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| MCU | KIDINS220 | 0.95 | 0.064 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| ABCD3 | KIDINS220 | 0.947 | 0.09 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| CHCHD3 | MCU | 0.903 | 0.312 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only | |
| DNAJC11 | KIDINS220 | 0.89 | 0.028 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| RNF185 | DNAJC11 | 0.887 | 0.088 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| DHRS7B | KIDINS220 | 0.801 | 0.026 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| RNF185 | KIDINS220 | 0.747 | 0.076 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| RNF185 | CHCHD3 | 0.618 | 0.14 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| CHSY1 | MCU | 0.588 | 0.102 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| TFRC | CHCHD3 | 0.567 | 0.24 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only | |
| TFRC | MCU | 0.535 | 0.172 | hein_WMM bioplex_WMM bioplex3_WMM boldt youn_WMM boldt_WMM WMM_only | |
| CHSY1 | CHCHD3 | 0.097 | 0.09 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| CHSY1 | KIDINS220 | 0.088 | 0.126 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| CHSY1 | TFRC | 0.08 | 0.094 | hein_WMM bioplex_WMM bioplex3_WMM WMM_only | |
| TFRC | DHRS7B | 0.053 | 0.135256528418 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| RNF185 | TFRC | 0.017 | 0.254 | hein_WMM bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| TFRC | DNAJC11 | 0.012 | 0.214 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only |
Related Complexes