hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_08879.1

Confidence: High

Genename	Protein Name	Uniprot Annotation Score	Links
RAD17	Cell cycle checkpoint protein RAD17 (hRad17) (RF-C/activator 1 homolog)	5	UniProt NCBI
RFC2	Replication factor C subunit 2 (Activator 1 40 kDa subunit) (A1 40 kDa subunit) (Activator 1 subunit 2) (Replication factor C 40 kDa subunit) (RF-C 40 kDa subunit) (RFC40)	5	UniProt NCBI
ATAD5	ATPase family AAA domain-containing protein 5 (Chromosome fragility-associated gene 1 protein)	5	UniProt NCBI
RFC3	Replication factor C subunit 3 (Activator 1 38 kDa subunit) (A1 38 kDa subunit) (Activator 1 subunit 3) (Replication factor C 38 kDa subunit) (RF-C 38 kDa subunit) (RFC38)	5	UniProt NCBI
RFC5	Replication factor C subunit 5 (Activator 1 36 kDa subunit) (A1 36 kDa subunit) (Activator 1 subunit 5) (Replication factor C 36 kDa subunit) (RF-C 36 kDa subunit) (RFC36)	5	UniProt NCBI
CHTF18	Chromosome transmission fidelity protein 18 homolog (hCTF18) (CHL12)	5	UniProt NCBI
DSCC1	Sister chromatid cohesion protein DCC1 (Defective in sister chromatid cohesion protein 1 homolog)	5	UniProt NCBI
CDC6	Cell division control protein 6 homolog (CDC6-related protein) (Cdc18-related protein) (HsCdc18) (p62(cdc6)) (HsCDC6)	5	UniProt NCBI
RFC4	Replication factor C subunit 4 (Activator 1 37 kDa subunit) (A1 37 kDa subunit) (Activator 1 subunit 4) (Replication factor C 37 kDa subunit) (RF-C 37 kDa subunit) (RFC37)	5	UniProt NCBI
CHTF8	Chromosome transmission fidelity protein 8 homolog (hCTF8)	4	UniProt NCBI
RB1	Retinoblastoma-associated protein (p105-Rb) (p110-RB1) (pRb) (Rb) (pp110)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0003689	1.60109129201e-22	0.727272727273	CHTF18 RAD17 DSCC1 RFC3 RFC4 RFC2 RFC5 CHTF8	DNA clamp loader activity
CORUM:2804	7.76518645207e-22	0.636363636364	RFC3 CHTF8 DSCC1 CHTF18 RFC4 RFC5 RFC2	CTF18-cohesion-RFC complex
CORUM:3070	6.21066076338e-21	0.636363636364	RFC3 CHTF8 DSCC1 CHTF18 RFC4 RFC5 RFC2	CTF18-cohesion-RFC-POLH complex
GO:0031390	4.67662755482e-18	0.636363636364	RFC3 CHTF8 DSCC1 CHTF18 RFC4 RFC5 RFC2	Ctf18 RFC-like complex
GO:1900262	2.10397814799e-17	0.636363636364	RFC3 CHTF8 DSCC1 CHTF18 RFC4 RFC5 RFC2	regulation of DNA-directed DNA polymerase activity
GO:1900264	2.10397814799e-17	0.636363636364	RFC3 CHTF8 DSCC1 CHTF18 RFC4 RFC5 RFC2	positive regulation of DNA-directed DNA polymerase activity
GO:0006275	6.27179353888e-17	0.909090909091	CHTF18 RAD17 DSCC1 CDC6 RFC3 RFC4 ATAD5 RFC5 RFC2 CHTF8	regulation of DNA replication
REAC:R-HSA-174411	1.98383310337e-15	0.636363636364	RFC3 CHTF8 DSCC1 CHTF18 RFC4 RFC5 RFC2	Polymerase switching on the C-strand of the telomere
CORUM:2810	5.52460635237e-15	0.454545454545	RAD17 RFC5 RFC4 RFC3 RFC2	RAD17-RFC complex
CORUM:2797	5.52460635237e-15	0.454545454545	RFC2 RFC4 RFC5 CHTF18 RFC3	PCNA-CHL12-RFC2-5 complex
CORUM:270	5.52460635237e-15	0.454545454545	RAD17 RFC5 RFC4 RFC3 RFC2	RAD17-RFC complex
CORUM:2202	5.52460635237e-15	0.454545454545	RFC2 RFC4 RFC5 CHTF18 RFC3	CHTF18-RFC2-5 complex
CORUM:266	5.52460635237e-15	0.454545454545	RAD17 RFC5 RFC4 RFC3 RFC2	RAD17-RFC complex
CORUM:2199	5.52460635237e-15	0.454545454545	RFC2 RFC4 RFC5 CHTF18 RFC3	CHTF18-RFC2-5 complex
REAC:R-HSA-174417	1.61930603028e-14	0.636363636364	RFC3 CHTF8 DSCC1 CHTF18 RFC4 RFC5 RFC2	Telomere C-strand (Lagging Strand) Synthesis
GO:0008094	2.82761276691e-14	0.818181818182	CHTF18 RAD17 DSCC1 RFC3 RFC4 ATAD5 RFC5 RFC2 CHTF8	ATP-dependent activity, acting on DNA
GO:0017116	9.93623097321e-14	0.636363636364	RFC3 CHTF8 DSCC1 CHTF18 RFC4 RFC5 RFC2	single-stranded DNA helicase activity
GO:0006260	2.09050518858e-13	0.909090909091	CHTF18 RAD17 DSCC1 CDC6 RFC3 RFC4 ATAD5 RFC5 RFC2 CHTF8	DNA replication
CORUM:274	3.09060412403e-13	0.454545454545	RAD17 RFC5 RFC4 RFC3 RFC2	9-1-1-RAD17-RFC complex
CORUM:268	3.09060412403e-13	0.454545454545	RAD17 RFC5 RFC4 RFC3 RFC2	9-1-1-RAD17-RFC complex
REAC:R-HSA-180786	3.47072449283e-13	0.636363636364	RFC3 CHTF8 DSCC1 CHTF18 RFC4 RFC5 RFC2	Extension of Telomeres
WP:WP2363	1.33505347023e-12	0.545454545455	RFC3 RAD17 DSCC1 CHTF18 RFC4 CHTF8	Gastric cancer network 2
GO:0090329	8.9247603052e-12	0.636363636364	RFC3 CHTF8 DSCC1 CHTF18 RFC4 RFC5 RFC2	regulation of DNA-templated DNA replication
CORUM:613	1.15314319164e-11	0.363636363636	RFC3 CHTF8 DSCC1 CHTF18	CTF18-CTF8-DCC1-RFC3 complex
CORUM:2200	1.15314319164e-11	0.363636363636	RFC2 RFC4 RFC5 RFC3	RFC2-5 subcomplex
CORUM:2201	1.15314319164e-11	0.363636363636	RFC2 RFC4 RFC5 RFC3	PCNA-RFC2-5 complex
REAC:R-HSA-176187	1.70905845824e-11	0.545454545455	RAD17 CDC6 RFC3 RFC4 RFC2 RFC5	Activation of ATR in response to replication stress
GO:0140097	2.72333362321e-11	0.818181818182	CHTF18 RAD17 DSCC1 RFC3 RFC4 ATAD5 RFC5 RFC2 CHTF8	catalytic activity, acting on DNA
REAC:R-HSA-157579	4.74253984172e-11	0.636363636364	RFC3 CHTF8 DSCC1 CHTF18 RFC4 RFC5 RFC2	Telomere Maintenance
CORUM:277	5.76350611564e-11	0.363636363636	RFC2 RFC4 RFC5 RFC3	RFC complex
CORUM:279	5.76350611564e-11	0.363636363636	RFC2 RFC4 RFC5 RFC3	RFC complex
CORUM:2799	5.76350611564e-11	0.363636363636	RFC2 RFC4 RFC5 RFC3	RFC complex
REAC:R-HSA-1640170	7.40068737515e-11	0.909090909091	CHTF18 RAD17 DSCC1 CDC6 RFC3 RB1 RFC4 RFC2 RFC5 CHTF8	Cell Cycle
GO:0003678	1.17296841983e-10	0.636363636364	RFC3 CHTF8 DSCC1 CHTF18 RFC4 RFC5 RFC2	DNA helicase activity
GO:0051052	1.68340350534e-10	0.909090909091	CHTF18 RAD17 DSCC1 CDC6 RFC3 RFC4 ATAD5 RFC5 RFC2 CHTF8	regulation of DNA metabolic process
CORUM:2203	1.72838910881e-10	0.363636363636	RFC2 RFC4 RFC5 RFC3	BRD4-RFC complex
GO:2000573	1.9700268993e-10	0.636363636364	RFC3 CHTF8 DSCC1 CHTF18 RFC4 RFC5 RFC2	positive regulation of DNA biosynthetic process
REAC:R-HSA-73886	2.63017512463e-10	0.636363636364	RFC3 CHTF8 DSCC1 CHTF18 RFC4 RFC5 RFC2	Chromosome Maintenance
CORUM:1003	8.05963357471e-10	0.363636363636	RFC2 RFC4 RFC5 RFC3	RC complex (Replication competent complex)
REAC:R-HSA-9709570	5.93840217276e-09	0.454545454545	RAD17 RFC5 RFC4 RFC3 RFC2	Impaired BRCA2 binding to RAD51
REAC:R-HSA-5685938	6.92576147827e-09	0.454545454545	RAD17 RFC5 RFC4 RFC3 RFC2	HDR through Single Strand Annealing (SSA)
WP:WP466	7.29484101893e-09	0.454545454545	RFC2 CDC6 RFC4 RFC5 RFC3	DNA replication
GO:2000278	7.35077323208e-09	0.636363636364	RFC3 CHTF8 DSCC1 CHTF18 RFC4 RFC5 RFC2	regulation of DNA biosynthetic process
REAC:R-HSA-5693616	1.22664782913e-08	0.454545454545	RAD17 RFC5 RFC4 RFC3 RFC2	Presynaptic phase of homologous DNA pairing and strand exchange
REAC:R-HSA-9675136	1.40140266656e-08	0.454545454545	RAD17 RFC5 RFC4 RFC3 RFC2	Diseases of DNA Double-Strand Break Repair
REAC:R-HSA-9701190	1.40140266656e-08	0.454545454545	RAD17 RFC5 RFC4 RFC3 RFC2	Defective homologous recombination repair (HRR) due to BRCA2 loss of function
REAC:R-HSA-5693579	1.81048126843e-08	0.454545454545	RAD17 RFC5 RFC4 RFC3 RFC2	Homologous DNA Pairing and Strand Exchange
GO:0004386	2.06552436833e-08	0.636363636364	RFC3 CHTF8 DSCC1 CHTF18 RFC4 RFC5 RFC2	helicase activity
CORUM:278	2.10621603952e-08	0.272727272727	RFC2 RFC4 RFC5	RFC core complex
CORUM:612	2.10621603952e-08	0.272727272727	CHTF18 DSCC1 CHTF8	CTF18-CTF8-DCC1 complex
CORUM:2806	2.10621603952e-08	0.272727272727	CHTF18 DSCC1 CHTF8	CTF18-CTF8-DCC1 complex
GO:0140657	2.26084842472e-08	0.818181818182	CHTF18 RAD17 DSCC1 RFC3 RFC4 ATAD5 RFC5 RFC2 CHTF8	ATP-dependent activity
GO:0051054	3.59928098431e-08	0.727272727273	CHTF18 ATAD5 DSCC1 RFC3 RFC4 RFC5 RFC2 CHTF8	positive regulation of DNA metabolic process
REAC:R-HSA-9675135	4.04869996877e-08	0.454545454545	RAD17 RFC5 RFC4 RFC3 RFC2	Diseases of DNA repair
GO:0005663	4.33992010508e-08	0.363636363636	RFC2 RFC4 RFC5 RFC3	DNA replication factor C complex
REAC:R-HSA-69109	4.48631562508e-08	0.363636363636	RFC2 RFC4 RFC5 RFC3	Leading Strand Synthesis
REAC:R-HSA-69091	4.48631562508e-08	0.363636363636	RFC2 RFC4 RFC5 RFC3	Polymerase switching
GO:0006259	7.55235167618e-08	0.909090909091	CHTF18 RAD17 DSCC1 CDC6 RFC3 RFC4 ATAD5 RFC5 RFC2 CHTF8	DNA metabolic process
KEGG:03430	7.78096363318e-08	0.363636363636	RFC2 RFC4 RFC5 RFC3	Mismatch repair
REAC:R-HSA-110312	8.15068333788e-08	0.363636363636	RFC2 RFC4 RFC5 RFC3	Translesion synthesis by REV1
REAC:R-HSA-5656121	8.15068333788e-08	0.363636363636	RFC2 RFC4 RFC5 RFC3	Translesion synthesis by POLI
GO:0051338	1.0127266232e-07	0.818181818182	RFC3 CHTF8 CDC6 DSCC1 CHTF18 RB1 RFC4 RFC5 RFC2	regulation of transferase activity
REAC:R-HSA-5655862	1.06544987436e-07	0.363636363636	RFC2 RFC4 RFC5 RFC3	Translesion synthesis by POLK
GO:0006261	1.06992282147e-07	0.636363636364	RFC3 CHTF8 DSCC1 CHTF18 RFC4 RFC5 RFC2	DNA-templated DNA replication
GO:0071897	1.1827539665e-07	0.636363636364	RFC3 CHTF8 DSCC1 CHTF18 RFC4 RFC5 RFC2	DNA biosynthetic process
GO:0140640	1.38858840462e-07	0.818181818182	CHTF18 RAD17 DSCC1 RFC3 RFC4 ATAD5 RFC5 RFC2 CHTF8	catalytic activity, acting on a nucleic acid
WP:WP531	1.59355434742e-07	0.363636363636	RFC2 RFC4 RFC5 RFC3	DNA mismatch repair
REAC:R-HSA-69242	1.7260862772e-07	0.545454545455	RFC3 CDC6 RB1 RFC4 RFC5 RFC2	S Phase
REAC:R-HSA-69481	1.7260862772e-07	0.545454545455	RAD17 CDC6 RFC3 RFC4 RFC2 RFC5	G2/M Checkpoints
REAC:R-HSA-110320	1.73383066136e-07	0.363636363636	RFC2 RFC4 RFC5 RFC3	Translesion Synthesis by POLH
REAC:R-HSA-5685942	1.88645310386e-07	0.454545454545	RAD17 RFC5 RFC4 RFC3 RFC2	HDR through Homologous Recombination (HRR)
REAC:R-HSA-69186	2.16645715224e-07	0.363636363636	RFC2 RFC4 RFC5 RFC3	Lagging Strand Synthesis
REAC:R-HSA-5651801	2.67518538301e-07	0.363636363636	RFC2 RFC4 RFC5 RFC3	PCNA-Dependent Long Patch Base Excision Repair
WP:WP5366	5.14535835656e-07	0.454545454545	RFC2 RFC5 RFC4 RFC3 ATAD5	NF1 copy number variation syndrome
KEGG:03030	5.15027537214e-07	0.363636363636	RFC2 RFC4 RFC5 RFC3	DNA replication
REAC:R-HSA-110373	5.64564812893e-07	0.363636363636	RFC2 RFC4 RFC5 RFC3	Resolution of AP sites via the multiple-nucleotide patch replacement pathway
REAC:R-HSA-5696397	5.64564812893e-07	0.363636363636	RFC2 RFC4 RFC5 RFC3	Gap-filling DNA repair synthesis and ligation in GG-NER
REAC:R-HSA-69473	7.74351075126e-07	0.454545454545	RAD17 RFC5 RFC4 RFC3 RFC2	G2/M DNA damage checkpoint
REAC:R-HSA-6804756	8.69270005003e-07	0.454545454545	RAD17 RFC5 RFC4 RFC3 RFC2	Regulation of TP53 Activity through Phosphorylation
REAC:R-HSA-5693607	9.20087246587e-07	0.454545454545	RAD17 RFC5 RFC4 RFC3 RFC2	Processing of DNA double-strand break ends
KEGG:03410	1.07612214936e-06	0.363636363636	RFC2 RFC4 RFC5 RFC3	Base excision repair
REAC:R-HSA-110314	1.2207307241e-06	0.363636363636	RFC2 RFC4 RFC5 RFC3	Recognition of DNA damage by PCNA-containing replication complex
REAC:R-HSA-5656169	1.40104195922e-06	0.363636363636	RFC2 RFC4 RFC5 RFC3	Termination of translesion DNA synthesis
REAC:R-HSA-69190	1.60057643707e-06	0.363636363636	RFC2 RFC4 RFC5 RFC3	DNA strand elongation
WP:WP4753	2.20391613469e-06	0.363636363636	RFC2 RFC4 RFC5 RFC3	Nucleotide excision repair
REAC:R-HSA-73933	2.32785713544e-06	0.363636363636	RFC2 RFC4 RFC5 RFC3	Resolution of Abasic Sites (AP sites)
REAC:R-HSA-110313	3.2779414915e-06	0.363636363636	RFC2 RFC4 RFC5 RFC3	Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template
KEGG:03420	3.67833724774e-06	0.363636363636	RFC2 RFC4 RFC5 RFC3	Nucleotide excision repair
REAC:R-HSA-69239	3.78560116396e-06	0.454545454545	RFC2 CDC6 RFC4 RFC5 RFC3	Synthesis of DNA
REAC:R-HSA-5693567	4.47244209705e-06	0.454545454545	RAD17 RFC5 RFC4 RFC3 RFC2	HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)
REAC:R-HSA-5696400	4.49197375051e-06	0.363636363636	RFC2 RFC4 RFC5 RFC3	Dual Incision in GG-NER
REAC:R-HSA-69620	5.06740135485e-06	0.545454545455	RAD17 CDC6 RFC3 RFC4 RFC2 RFC5	Cell Cycle Checkpoints
REAC:R-HSA-5693538	5.68529443791e-06	0.454545454545	RAD17 RFC5 RFC4 RFC3 RFC2	Homology Directed Repair
REAC:R-HSA-73893	7.89342534617e-06	0.363636363636	RFC2 RFC4 RFC5 RFC3	DNA Damage Bypass
REAC:R-HSA-5633007	1.29654337939e-05	0.454545454545	RAD17 RFC5 RFC4 RFC3 RFC2	Regulation of TP53 Activity
GO:0051347	1.35882191211e-05	0.636363636364	RFC3 CHTF8 DSCC1 CHTF18 RFC4 RFC5 RFC2	positive regulation of transferase activity
REAC:R-HSA-5693532	1.5742095756e-05	0.454545454545	RAD17 RFC5 RFC4 RFC3 RFC2	DNA Double-Strand Break Repair
WP:WP5114	1.92149687159e-05	0.363636363636	RFC2 RFC4 RFC5 RFC3	Nucleotide excision repair in xeroderma pigmentosum
REAC:R-HSA-69306	2.55094081082e-05	0.454545454545	RFC2 CDC6 RFC4 RFC5 RFC3	DNA Replication
REAC:R-HSA-6782210	2.61992380384e-05	0.363636363636	RFC2 RFC4 RFC5 RFC3	Gap-filling DNA repair synthesis and ligation in TC-NER
REAC:R-HSA-6782135	2.79351170616e-05	0.363636363636	RFC2 RFC4 RFC5 RFC3	Dual incision in TC-NER
GO:0005694	3.107722397e-05	0.909090909091	CHTF18 RAD17 DSCC1 RFC3 RB1 RFC4 ATAD5 RFC5 RFC2 CHTF8	chromosome
CORUM:2805	3.41979277617e-05	0.181818181818	CHTF8 DSCC1	CTF8-DCC1 subcomplex
WP:WP2446	3.7301965352e-05	0.363636363636	RFC3 RB1 RFC4 RFC5	Retinoblastoma gene in cancer
GO:0050790	4.65501909918e-05	0.818181818182	RFC3 CHTF8 CDC6 DSCC1 CHTF18 RB1 RFC4 RFC5 RFC2	regulation of catalytic activity
REAC:R-HSA-73884	5.61480508088e-05	0.363636363636	RFC2 RFC4 RFC5 RFC3	Base Excision Repair
WP:WP4932	5.81288631739e-05	0.363636363636	RFC2 RB1 CHTF18 RFC5	7q11 23 copy number variation syndrome
REAC:R-HSA-6781827	5.92018899877e-05	0.363636363636	RFC2 RFC4 RFC5 RFC3	Transcription-Coupled Nucleotide Excision Repair (TC-NER)
REAC:R-HSA-5696399	8.02053265718e-05	0.363636363636	RFC2 RFC4 RFC5 RFC3	Global Genome Nucleotide Excision Repair (GG-NER)
WP:WP4946	0.000111932560618	0.363636363636	RFC2 RFC4 RFC5 RFC3	DNA repair pathways full network
CORUM:6304	0.000205019103882	0.181818181818	CHTF18 DSCC1	DDX11-Ctf18-RFC complex
REAC:R-HSA-69278	0.000216767134013	0.545454545455	RFC3 CDC6 RB1 RFC4 RFC5 RFC2	Cell Cycle, Mitotic
REAC:R-HSA-5696398	0.000231665446959	0.363636363636	RFC2 RFC4 RFC5 RFC3	Nucleotide Excision Repair
REAC:R-HSA-73894	0.000420365176803	0.454545454545	RAD17 RFC5 RFC4 RFC3 RFC2	DNA Repair
CORUM:435	0.000512126948792	0.181818181818	RFC2 RFC4	BASC (Ab 81) complex (BRCA1-associated genome surveillance complex)
REAC:R-HSA-3700989	0.000685690459288	0.454545454545	RAD17 RFC5 RFC4 RFC3 RFC2	Transcriptional Regulation by TP53
GO:0019219	0.000706346376562	1.0	CHTF18 RAD17 DSCC1 CDC6 RFC3 RB1 RFC4 ATAD5 RFC5 RFC2 CHTF8	regulation of nucleobase-containing compound metabolic process
CORUM:434	0.000955185435728	0.181818181818	RFC2 RFC4	BASC (Ab 80) complex (BRCA1-associated genome surveillance complex)
GO:0044093	0.000971417854021	0.727272727273	RFC3 CHTF8 DSCC1 CHTF18 RB1 RFC4 RFC5 RFC2	positive regulation of molecular function
GO:0065009	0.00169704827811	0.818181818182	RFC3 CHTF8 CDC6 DSCC1 CHTF18 RB1 RFC4 RFC5 RFC2	regulation of molecular function
CORUM:433	0.00224781298839	0.181818181818	RFC2 RFC4	BASC complex (BRCA1-associated genome surveillance complex)
GO:0043085	0.00230626431274	0.636363636364	RFC3 CHTF8 DSCC1 CHTF18 RFC4 RFC5 RFC2	positive regulation of catalytic activity
GO:0005657	0.00574280977106	0.363636363636	RFC2 RFC4 RFC5 RFC3	replication fork
GO:0140513	0.00704522774331	0.727272727273	RFC3 CHTF8 DSCC1 CHTF18 RB1 RFC4 RFC5 RFC2	nuclear protein-containing complex
REAC:R-HSA-212436	0.0103316302063	0.545454545455	RFC3 RAD17 RB1 RFC4 RFC2 RFC5	Generic Transcription Pathway
GO:0090304	0.0119029444692	1.0	CHTF18 RAD17 DSCC1 CDC6 RFC3 RB1 RFC4 ATAD5 RFC5 RFC2 CHTF8	nucleic acid metabolic process
WP:000000	0.0140861908637	1.0	CHTF18 RAD17 DSCC1 CDC6 RFC3 RB1 RFC4 ATAD5 RFC5 RFC2 CHTF8	WIKIPATHWAYS
GO:0043232	0.0141556237682	1.0	CHTF18 RAD17 DSCC1 CDC6 RFC3 RB1 RFC4 ATAD5 RFC5 RFC2 CHTF8	intracellular non-membrane-bounded organelle
GO:0043228	0.0141556237682	1.0	CHTF18 RAD17 DSCC1 CDC6 RFC3 RB1 RFC4 ATAD5 RFC5 RFC2 CHTF8	non-membrane-bounded organelle
REAC:R-HSA-73857	0.0192733308151	0.545454545455	RFC3 RAD17 RB1 RFC4 RFC2 RFC5	RNA Polymerase II Transcription
GO:0051171	0.0210338225181	1.0	CHTF18 RAD17 DSCC1 CDC6 RFC3 RB1 RFC4 ATAD5 RFC5 RFC2 CHTF8	regulation of nitrogen compound metabolic process
GO:0080090	0.0275866537037	1.0	CHTF18 RAD17 DSCC1 CDC6 RFC3 RB1 RFC4 ATAD5 RFC5 RFC2 CHTF8	regulation of primary metabolic process
GO:0045935	0.0322976894115	0.727272727273	CHTF18 ATAD5 DSCC1 RFC3 RFC4 RFC5 RFC2 CHTF8	positive regulation of nucleobase-containing compound metabolic process
GO:0006139	0.0379532315546	1.0	CHTF18 RAD17 DSCC1 CDC6 RFC3 RB1 RFC4 ATAD5 RFC5 RFC2 CHTF8	nucleobase-containing compound metabolic process
REAC:R-HSA-74160	0.0390724328074	0.545454545455	RFC3 RAD17 RB1 RFC4 RFC2 RFC5	Gene expression (Transcription)
CORUM:5663	0.049976851631	0.0909090909091	RB1	TRIM27-RB1 complex
CORUM:1132	0.049976851631	0.0909090909091	RFC4	RFC2-RIalpha complex
CORUM:1131	0.049976851631	0.0909090909091	RFC2	RFC2-RIalpha complex

Edges

Protein 1	Protein 2	Score	ProteomeHD
RFC5	RFC4	1.0	0.946
RFC2	RFC5	1.0	0.978
RFC3	RFC5	1.0	0.898
RFC3	RFC4	1.0	0.802
DSCC1	CHTF8	1.0	0.360666666667
CHTF18	RFC5	1.0	0.342
DSCC1	RFC3	1.0	0.368
CHTF18	DSCC1	1.0	0.328
CHTF18	RFC4	0.999	0.272
RFC2	RFC4	0.999	0.942
DSCC1	RFC5	0.999	0.464
RFC2	RFC3	0.999	0.948
DSCC1	RFC2	0.999	0.388
CHTF8	RFC5	0.999	0.322
RAD17	RFC4	0.999	0.228
DSCC1	RFC4	0.999	0.48
RAD17	RFC5	0.999	0.216
CHTF8	RFC4	0.999	0.38
ATAD5	RFC5	0.998	0.206
ATAD5	RFC4	0.996	0.258
RAD17	RFC3	0.988	0.204
RFC2	ATAD5	0.986	0.29
RAD17	RFC2	0.985	0.222
CHTF18	RFC2	0.982	0.316
CHTF18	CHTF8	0.979	0.37
RFC5	RB1	0.97	0.11
RFC5	CDC6	0.953	0.196
CHTF18	RFC3	0.947	0.258
CHTF8	RFC2	0.893	0.344
CHTF8	RFC3	0.872	0.208
RFC3	CDC6	0.737	0.134
ATAD5	CDC6	0.684	0.162
ATAD5	RFC3	0.643	0.216
CHTF8	RAD17	0.631	0.23
CHTF18	RAD17	0.589	0.164
RAD17	ATAD5	0.583	0.144
DSCC1	RAD17	0.535	0.192
CHTF18	ATAD5	0.426	0.132
DSCC1	ATAD5	0.263	0.162
CHTF8	ATAD5	0.202	0.098
ATAD5	RB1	0.192	0.248
RFC3	RB1	0.165	0.092
RFC4	RB1	0.144	0.128
CDC6	RFC4	0.122	0.262
RAD17	RB1	0.095	0.114
CHTF18	RB1	0.076	0.186
CHTF8	RB1	0.061	0.094
RFC2	RB1	0.058	0.096
CDC6	RB1	0.053	0.13
DSCC1	RB1	0.043	0.136
RFC2	CDC6	0.03	0.188

Related Complexes

Genename	Complexes
RAD17	huMAP3_00703.1 huMAP3_01448.1 huMAP3_02396.1 huMAP3_02854.1 huMAP3_03241.1 huMAP3_07313.1 huMAP3_08854.1 huMAP3_08879.1 huMAP3_10568.1 huMAP3_12787.1
RFC2	huMAP3_00703.1 huMAP3_02854.1 huMAP3_03241.1 huMAP3_07313.1 huMAP3_08854.1 huMAP3_08879.1 huMAP3_09476.1 huMAP3_10568.1 huMAP3_12727.1 huMAP3_12839.1 huMAP3_14232.1
ATAD5	huMAP3_00703.1 huMAP3_02396.1 huMAP3_02854.1 huMAP3_03241.1 huMAP3_07127.1 huMAP3_07313.1 huMAP3_08497.1 huMAP3_08854.1 huMAP3_08879.1 huMAP3_09476.1 huMAP3_10568.1 huMAP3_12727.1 huMAP3_12839.1 huMAP3_13325.1 huMAP3_14232.1
RFC3	huMAP3_00703.1 huMAP3_02396.1 huMAP3_02854.1 huMAP3_07127.1 huMAP3_07313.1 huMAP3_07717.1 huMAP3_08854.1 huMAP3_08879.1 huMAP3_09525.1 huMAP3_10568.1 huMAP3_12727.1 huMAP3_12839.1 huMAP3_14232.1
RFC5	huMAP3_00703.1 huMAP3_02396.1 huMAP3_02854.1 huMAP3_03241.1 huMAP3_07127.1 huMAP3_07313.1 huMAP3_08497.1 huMAP3_08854.1 huMAP3_08879.1 huMAP3_09476.1 huMAP3_10568.1 huMAP3_12727.1 huMAP3_12839.1 huMAP3_13325.1 huMAP3_14232.1
CHTF18	huMAP3_00015.1 huMAP3_00703.1 huMAP3_02396.1 huMAP3_05600.1 huMAP3_07127.1 huMAP3_07313.1 huMAP3_08854.1 huMAP3_08879.1 huMAP3_10568.1 huMAP3_11446.1 huMAP3_11579.1 huMAP3_12727.1 huMAP3_12839.1 huMAP3_13325.1 huMAP3_14232.1
DSCC1	huMAP3_00015.1 huMAP3_00703.1 huMAP3_02396.1 huMAP3_02854.1 huMAP3_03241.1 huMAP3_07127.1 huMAP3_07313.1 huMAP3_08854.1 huMAP3_08879.1 huMAP3_10568.1 huMAP3_12727.1 huMAP3_12839.1 huMAP3_13325.1 huMAP3_14232.1
CDC6	huMAP3_00703.1 huMAP3_01929.1 huMAP3_02854.1 huMAP3_03241.1 huMAP3_08854.1 huMAP3_08879.1 huMAP3_10568.1 huMAP3_10573.1 huMAP3_12194.1 huMAP3_12727.1 huMAP3_14305.1
RFC4	huMAP3_00703.1 huMAP3_02396.1 huMAP3_02854.1 huMAP3_03241.1 huMAP3_07127.1 huMAP3_07313.1 huMAP3_08497.1 huMAP3_08854.1 huMAP3_08879.1 huMAP3_09476.1 huMAP3_10568.1 huMAP3_12727.1 huMAP3_12839.1 huMAP3_14232.1
CHTF8	huMAP3_00015.1 huMAP3_00703.1 huMAP3_02396.1 huMAP3_02520.1 huMAP3_02854.1 huMAP3_03241.1 huMAP3_07127.1 huMAP3_07313.1 huMAP3_08854.1 huMAP3_08879.1 huMAP3_10568.1 huMAP3_11579.1 huMAP3_12727.1 huMAP3_12839.1 huMAP3_13325.1 huMAP3_14232.1
RB1	huMAP3_02854.1 huMAP3_03241.1 huMAP3_06586.1 huMAP3_08879.1 huMAP3_11168.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_08879.1