hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08888.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ABCB9 | ABC-type oligopeptide transporter ABCB9 (EC 7.4.2.6) (ATP-binding cassette sub-family B member 9) (ATP-binding cassette transporter 9) (ABC transporter 9 protein) (hABCB9) (TAP-like protein) (TAPL) | 5 | UniProt NCBI |
| PIGH | Phosphatidylinositol N-acetylglucosaminyltransferase subunit H (Phosphatidylinositol-glycan biosynthesis class H protein) (PIG-H) | 5 | UniProt NCBI |
| PIGQ | Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q (N-acetylglucosamyl transferase component GPI1) (Phosphatidylinositol-glycan biosynthesis class Q protein) (PIG-Q) | 5 | UniProt NCBI |
| CYP4F11 | Cytochrome P450 4F11 (CYPIVF11) (EC 1.14.14.1) (3-hydroxy fatty acids omega-hydroxylase CYP4F11) (Docosahexaenoic acid omega-hydroxylase) (EC 1.14.14.79) (Long-chain fatty acid omega-monooxygenase) (EC 1.14.14.80) (Phylloquinone omega-hydroxylase CYP4F11) (EC 1.14.14.78) | 5 | UniProt NCBI |
| ADCY7 | Adenylate cyclase type 7 (EC 4.6.1.1) (ATP pyrophosphate-lyase 7) (Adenylate cyclase type VII) (Adenylyl cyclase 7) | 5 | UniProt NCBI |
| TLR3 | Toll-like receptor 3 (CD antigen CD283) | 5 | UniProt NCBI |
| ABCC10 | ATP-binding cassette sub-family C member 10 (EC 7.6.2.2) (EC 7.6.2.3) (Multidrug resistance-associated protein 7) | 5 | UniProt NCBI |
| PIGP | Phosphatidylinositol N-acetylglucosaminyltransferase subunit P (Down syndrome critical region protein 5) (Down syndrome critical region protein C) (Phosphatidylinositol-glycan biosynthesis class P protein) (PIG-P) | 5 | UniProt NCBI |
| SLC4A11 | Solute carrier family 4 member 11 (Sodium borate cotransporter 1) (NaBC1) | 5 | UniProt NCBI |
| PIGA | Phosphatidylinositol N-acetylglucosaminyltransferase subunit A (EC 2.4.1.198) (GlcNAc-PI synthesis protein) (Phosphatidylinositol-glycan biosynthesis class A protein) (PIG-A) | 5 | UniProt NCBI |
| ANO1 | Anoctamin-1 (Discovered on gastrointestinal stromal tumors protein 1) (Oral cancer overexpressed protein 2) (Transmembrane protein 16A) (Tumor-amplified and overexpressed sequence 2) | 5 | UniProt NCBI |
| DHRS3 | Short-chain dehydrogenase/reductase 3 (EC 1.1.1.300) (DD83.1) (Retinal short-chain dehydrogenase/reductase 1) (retSDR1) (Retinol dehydrogenase 17) (Short chain dehydrogenase/reductase family 16C member 1) | 5 | UniProt NCBI |
| IL18RAP | Interleukin-18 receptor accessory protein (IL-18 receptor accessory protein) (IL-18RAcP) (EC 3.2.2.6) (Accessory protein-like) (AcPL) (CD218 antigen-like family member B) (CDw218b) (IL-1R accessory protein-like) (IL-1RAcPL) (Interleukin-1 receptor 7) (IL-1R-7) (IL-1R7) (Interleukin-18 receptor accessory protein-like) (Interleukin-18 receptor beta) (IL-18R-beta) (IL-18Rbeta) (CD antigen CD218b) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:118 | 3.08880131998e-08 | 0.230769230769 | PIGH PIGA PIGQ | GPI-GnT activity complex |
| GO:0000506 | 9.40213012535e-08 | 0.307692307692 | PIGH PIGP PIGA PIGQ | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex |
| KEGG:00563 | 1.27756465142e-07 | 0.307692307692 | PIGH PIGP PIGA PIGQ | Glycosylphosphatidylinositol (GPI)-anchor biosynthesis |
| REAC:R-HSA-162710 | 3.28961196798e-05 | 0.230769230769 | PIGH PIGA PIGP | Synthesis of glycosylphosphatidylinositol (GPI) |
| GO:0006506 | 0.00019795084604 | 0.307692307692 | PIGH PIGP PIGA PIGQ | GPI anchor biosynthetic process |
| GO:0006505 | 0.00023553955807 | 0.307692307692 | PIGH PIGP PIGA PIGQ | GPI anchor metabolic process |
| GO:0005789 | 0.00143064168831 | 0.615384615385 | CYP4F11 PIGQ PIGP ABCB9 DHRS3 PIGH PIGA TLR3 | endoplasmic reticulum membrane |
| GO:0098827 | 0.00161520425119 | 0.615384615385 | CYP4F11 PIGQ PIGP ABCB9 DHRS3 PIGH PIGA TLR3 | endoplasmic reticulum subcompartment |
| GO:0042175 | 0.00172432020183 | 0.615384615385 | CYP4F11 PIGQ PIGP ABCB9 DHRS3 PIGH PIGA TLR3 | nuclear outer membrane-endoplasmic reticulum membrane network |
| REAC:R-HSA-163125 | 0.00635592495791 | 0.230769230769 | PIGH PIGA PIGP | Post-translational modification: synthesis of GPI-anchored proteins |
| GO:0009247 | 0.00833329666432 | 0.307692307692 | PIGH PIGP PIGA PIGQ | glycolipid biosynthetic process |
| GO:0006497 | 0.0123598285834 | 0.307692307692 | PIGH PIGP PIGA PIGQ | protein lipidation |
| GO:0042158 | 0.0131507388505 | 0.307692307692 | PIGH PIGP PIGA PIGQ | lipoprotein biosynthetic process |
| GO:0031984 | 0.0136910749789 | 0.615384615385 | CYP4F11 PIGQ PIGP ABCB9 DHRS3 PIGH PIGA TLR3 | organelle subcompartment |
| HP:0010841 | 0.0200069455336 | 0.230769230769 | PIGQ PIGA PIGP | Multifocal epileptiform discharges |
| KEGG:02010 | 0.0230676515471 | 0.153846153846 | ABCB9 ABCC10 | ABC transporters |
| HP:0020221 | 0.024231963902 | 0.230769230769 | PIGQ PIGA PIGP | Clonic seizure |
| KEGG:01100 | 0.0274184578426 | 0.461538461538 | PIGQ PIGP ADCY7 PIGH PIGA DHRS3 | Metabolic pathways |
| HP:0011146 | 0.0283956527006 | 0.307692307692 | PIGQ TLR3 PIGA PIGP | Dialeptic seizure |
| GO:0042157 | 0.0286596158255 | 0.307692307692 | PIGH PIGP PIGA PIGQ | lipoprotein metabolic process |
| GO:1903509 | 0.0332499437356 | 0.307692307692 | PIGH PIGP PIGA PIGQ | liposaccharide metabolic process |
| GO:0006664 | 0.0332499437356 | 0.307692307692 | PIGH PIGP PIGA PIGQ | glycolipid metabolic process |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD |
|---|---|---|---|
| PIGP | PIGH | 1.0 | |
| PIGH | SLC4A11 | 0.997 | 0.136 |
| PIGH | CYP4F11 | 0.997 | 0.1 |
| PIGH | ADCY7 | 0.993 | 0.078 |
| PIGA | PIGH | 0.992 | 0.11 |
| PIGH | ANO1 | 0.991 | 0.092 |
| PIGH | PIGQ | 0.99 | 0.094 |
| ABCC10 | PIGH | 0.99 | 0.08 |
| DHRS3 | PIGH | 0.99 | 0.06 |
| IL18RAP | PIGH | 0.983 | |
| PIGA | PIGP | 0.97 | |
| PIGA | IL18RAP | 0.969 | |
| ABCB9 | PIGH | 0.967 | |
| TLR3 | PIGH | 0.959 | 0.116 |
| PIGP | ANO1 | 0.904 | |
| PIGP | SLC4A11 | 0.902 | |
| PIGP | CYP4F11 | 0.902 | |
| CYP4F11 | SLC4A11 | 0.902 | 0.076 |
| CYP4F11 | ANO1 | 0.902 | 0.124 |
| DHRS3 | SLC4A11 | 0.902 | 0.052 |
| SLC4A11 | ADCY7 | 0.902 | 0.094 |
| SLC4A11 | ANO1 | 0.902 | 0.044 |
| CYP4F11 | ADCY7 | 0.902 | 0.088 |
| PIGP | ADCY7 | 0.902 | |
| DHRS3 | CYP4F11 | 0.902 | 0.252 |
| ABCB9 | PIGQ | 0.829 | |
| ABCC10 | PIGA | 0.828 | 0.144 |
| ABCB9 | DHRS3 | 0.786 | |
| PIGA | DHRS3 | 0.776 | 0.078 |
| PIGP | DHRS3 | 0.768 | |
| ABCC10 | PIGQ | 0.763 | 0.078 |
| ABCB9 | ABCC10 | 0.734 | |
| PIGQ | CYP4F11 | 0.73 | 0.126 |
| PIGQ | SLC4A11 | 0.73 | 0.054 |
| ABCB9 | SLC4A11 | 0.715 | |
| ABCB9 | CYP4F11 | 0.715 | |
| ABCC10 | SLC4A11 | 0.715 | 0.054 |
| ABCC10 | CYP4F11 | 0.715 | 0.086 |
| ANO1 | ADCY7 | 0.714 | 0.114 |
| PIGA | SLC4A11 | 0.675 | 0.102 |
| PIGP | PIGQ | 0.675 | |
| PIGA | CYP4F11 | 0.675 | 0.16 |
| ABCB9 | PIGP | 0.675 | |
| PIGQ | ANO1 | 0.675 | 0.118 |
| ABCB9 | ANO1 | 0.675 | |
| ABCB9 | ADCY7 | 0.675 | |
| ABCC10 | PIGP | 0.675 | |
| PIGA | ADCY7 | 0.656 | 0.076 |
| PIGQ | ADCY7 | 0.656 | 0.11 |
| DHRS3 | PIGQ | 0.653 | 0.134 |
| PIGA | PIGQ | 0.639 | 0.108 |
| ABCB9 | PIGA | 0.623 | |
| PIGA | ANO1 | 0.606 | 0.066 |
| ABCC10 | DHRS3 | 0.527 | 0.062 |
| DHRS3 | ADCY7 | 0.455 | 0.114 |
| DHRS3 | ANO1 | 0.401 | 0.124 |
| ABCC10 | ADCY7 | 0.345 | 0.084 |
| ABCC10 | ANO1 | 0.343 | 0.074 |
Related Complexes