hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08895.1
Confidence: High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
BOD1L1 | Biorientation of chromosomes in cell division protein 1-like 1 | 5 | UniProt   NCBI |
SETD1A | Histone-lysine N-methyltransferase SETD1A (EC 2.1.1.364) (Lysine N-methyltransferase 2F) (SET domain-containing protein 1A) (hSET1A) (Set1/Ash2 histone methyltransferase complex subunit SET1) | 5 | UniProt   NCBI |
SETD1B | Histone-lysine N-methyltransferase SETD1B (EC 2.1.1.364) (Lysine N-methyltransferase 2G) (SET domain-containing protein 1B) (hSET1B) | 5 | UniProt   NCBI |
KMT2A | Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.364) (ALL-1) (CXXC-type zinc finger protein 7) (Cysteine methyltransferase KMT2A) (EC 2.1.1.-) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)] | 5 | UniProt   NCBI |
CXXC1 | CXXC-type zinc finger protein 1 (CpG-binding protein) (PHD finger and CXXC domain-containing protein 1) | 5 | UniProt   NCBI |
KMT2D | Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.364) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2) | 5 | UniProt   NCBI |
KDM6A | Lysine-specific demethylase 6A (EC 1.14.11.68) (Histone demethylase UTX) (Ubiquitously-transcribed TPR protein on the X chromosome) (Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein) ([histone H3]-trimethyl-L-lysine(27) demethylase 6A) | 5 | UniProt   NCBI |
HCFC1 | Host cell factor 1 (HCF) (HCF-1) (C1 factor) (CFF) (VCAF) (VP16 accessory protein) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6] | 5 | UniProt   NCBI |
HCFC2 | Host cell factor 2 (HCF-2) (C2 factor) | 5 | UniProt   NCBI |
DPY30 | Protein dpy-30 homolog (Dpy-30-like protein) (Dpy-30L) | 5 | UniProt   NCBI |
ASH2L | Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein) | 5 | UniProt   NCBI |
RBBP5 | Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3) | 5 | UniProt   NCBI |
KMT2C | Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.364) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3) | 5 | UniProt   NCBI |
BOD1 | Biorientation of chromosomes in cell division protein 1 (Biorientation defective protein 1) (Protein FAM44B) | 5 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-9772755 | 2.81901590647e-35 | 1.0 | BOD1L1 HCFC1 SETD1A KMT2C CXXC1 KMT2D KMT2A RBBP5 ASH2L HCFC2 BOD1 DPY30 SETD1B KDM6A | Formation of WDR5-containing histone-modifying complexes |
  GO:0035097 | 1.03474541866e-29 | 1.0 | BOD1L1 HCFC1 SETD1A KMT2C CXXC1 KMT2D KMT2A RBBP5 ASH2L HCFC2 BOD1 DPY30 SETD1B KDM6A | histone methyltransferase complex |
  GO:0034708 | 2.30968433148e-27 | 1.0 | BOD1L1 HCFC1 SETD1A KMT2C CXXC1 KMT2D KMT2A RBBP5 ASH2L HCFC2 BOD1 DPY30 SETD1B KDM6A | methyltransferase complex |
  REAC:R-HSA-212165 | 1.47423780358e-25 | 1.0 | BOD1L1 HCFC1 SETD1A KMT2C CXXC1 KMT2D KMT2A RBBP5 ASH2L HCFC2 BOD1 DPY30 SETD1B KDM6A | Epigenetic regulation of gene expression |
  CORUM:6470 | 2.74620770968e-25 | 0.642857142857 | BOD1L1 HCFC1 HCFC2 BOD1 CXXC1 SETD1B ASH2L DPY30 RBBP5 | Set1B complex |
  GO:0048188 | 4.09748972345e-25 | 0.714285714286 | BOD1L1 HCFC1 HCFC2 BOD1 CXXC1 DPY30 ASH2L SETD1A SETD1B RBBP5 | Set1C/COMPASS complex |
  CORUM:6469 | 7.60763222544e-19 | 0.5 | HCFC1 HCFC2 CXXC1 ASH2L SETD1A DPY30 RBBP5 | Set1A complex |
  CORUM:6460 | 2.42967869538e-15 | 0.428571428571 | HCFC1 HCFC2 KMT2D ASH2L DPY30 RBBP5 | MLL2 complex |
  GO:1990234 | 6.44503492717e-14 | 1.0 | BOD1L1 HCFC1 SETD1A KMT2C CXXC1 KMT2D KMT2A RBBP5 ASH2L HCFC2 BOD1 DPY30 SETD1B KDM6A | transferase complex |
  REAC:R-HSA-3214841 | 1.18385361433e-13 | 0.571428571429 | SETD1A KMT2D SETD1B KMT2A ASH2L KMT2C DPY30 RBBP5 | PKMTs methylate histone lysines |
  REAC:R-HSA-8936459 | 4.62206939812e-13 | 0.571428571429 | SETD1A KMT2D SETD1B KMT2A ASH2L KMT2C DPY30 RBBP5 | RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function |
  REAC:R-HSA-4839726 | 4.74685939501e-13 | 0.714285714286 | HCFC1 SETD1A KDM6A KMT2D KMT2A ASH2L KMT2C DPY30 SETD1B RBBP5 | Chromatin organization |
  REAC:R-HSA-3247509 | 4.74685939501e-13 | 0.714285714286 | HCFC1 SETD1A KDM6A KMT2D KMT2A ASH2L KMT2C DPY30 SETD1B RBBP5 | Chromatin modifying enzymes |
  REAC:R-HSA-74160 | 4.9505556381e-13 | 1.0 | BOD1L1 HCFC1 SETD1A KMT2C CXXC1 KMT2D KMT2A RBBP5 ASH2L HCFC2 BOD1 DPY30 SETD1B KDM6A | Gene expression (Transcription) |
  CORUM:6462 | 1.05213604103e-12 | 0.357142857143 | ASH2L KMT2A RBBP5 HCFC1 DPY30 | MLL1 complex |
  CORUM:6461 | 2.36609068241e-12 | 0.357142857143 | ASH2L KMT2C RBBP5 KDM6A DPY30 | MLL3 complex |
  CORUM:6467 | 2.36609068241e-12 | 0.357142857143 | ASH2L DPY30 RBBP5 KMT2D KDM6A | MLL4 complex |
  CORUM:5195 | 4.72975168612e-12 | 0.357142857143 | ASH2L KMT2C RBBP5 KDM6A DPY30 | PTIP-HMT complex |
  GO:0044666 | 5.11838675012e-12 | 0.428571428571 | KMT2C KMT2D KDM6A ASH2L DPY30 RBBP5 | MLL3/4 complex |
  GO:0140513 | 9.35801838804e-12 | 1.0 | BOD1L1 HCFC1 SETD1A KMT2C CXXC1 KMT2D KMT2A RBBP5 ASH2L HCFC2 BOD1 DPY30 SETD1B KDM6A | nuclear protein-containing complex |
  CORUM:3075 | 1.48496723579e-11 | 0.357142857143 | ASH2L KMT2C RBBP5 KMT2D KDM6A | UTX-MLL2/3 complex |
  CORUM:6851 | 1.3739312217e-10 | 0.285714285714 | KMT2A RBBP5 DPY30 ASH2L | MWRAD complex (MLL1, WDR5, RBBP5, ASH2L, DPY30) |
  CORUM:2730 | 4.11953677117e-10 | 0.285714285714 | ASH2L RBBP5 SETD1B CXXC1 | Set1B complex |
  CORUM:2731 | 4.11953677117e-10 | 0.285714285714 | SETD1A RBBP5 CXXC1 ASH2L | Set1A complex |
  GO:1902494 | 8.83644423557e-10 | 1.0 | BOD1L1 HCFC1 SETD1A KMT2C CXXC1 KMT2D KMT2A RBBP5 ASH2L HCFC2 BOD1 DPY30 SETD1B KDM6A | catalytic complex |
  CORUM:1400 | 9.60698908367e-10 | 0.285714285714 | KMT2C RBBP5 KMT2D ASH2L | ASCOM complex |
  CORUM:1256 | 9.60698908367e-10 | 0.285714285714 | KMT2A RBBP5 HCFC1 ASH2L | MLL-HCF complex |
  REAC:R-HSA-8878171 | 1.29448620866e-09 | 0.571428571429 | SETD1A KMT2D SETD1B KMT2A ASH2L KMT2C DPY30 RBBP5 | Transcriptional regulation by RUNX1 |
  WP:WP5351 | 4.92899401431e-09 | 0.357142857143 | ASH2L KMT2C RBBP5 KDM6A DPY30 | Kleefstra syndrome |
  CORUM:1401 | 5.75472908671e-09 | 0.285714285714 | SETD1A RBBP5 KMT2D KMT2A | MOF complex |
  GO:0071339 | 8.0807901501e-09 | 0.428571428571 | HCFC1 HCFC2 KMT2A ASH2L DPY30 RBBP5 | MLL1 complex |
  GO:0042800 | 8.30275522242e-09 | 0.357142857143 | SETD1A KMT2C SETD1B KMT2D KMT2A | histone H3K4 methyltransferase activity |
  GO:0044665 | 9.94091378428e-09 | 0.428571428571 | HCFC1 HCFC2 KMT2A ASH2L DPY30 RBBP5 | MLL1/2 complex |
  KEGG:00310 | 8.94112607605e-08 | 0.357142857143 | SETD1A KMT2C SETD1B KMT2D KMT2A | Lysine degradation |
  REAC:R-HSA-5619507 | 1.01532521518e-07 | 0.428571428571 | KMT2C KMT2D KDM6A ASH2L DPY30 RBBP5 | Activation of HOX genes during differentiation |
  REAC:R-HSA-5617472 | 1.01532521518e-07 | 0.428571428571 | KMT2C KMT2D KDM6A ASH2L DPY30 RBBP5 | Activation of anterior HOX genes in hindbrain development during early embryogenesis |
  CORUM:1399 | 1.4600392795e-07 | 0.214285714286 | RBBP5 KMT2D ASH2L | WDR5-ASH2L-RBBP5-MLL2 complex |
  CORUM:6849 | 1.4600392795e-07 | 0.214285714286 | RBBP5 DPY30 ASH2L | WRAD complex (WDR5, RBBP5, ASH2L, DPY30) |
  CORUM:6457 | 1.4600392795e-07 | 0.214285714286 | KMT2A ASH2L RBBP5 | MLL1 core complex |
  WP:WP2369 | 2.64062012181e-07 | 0.357142857143 | SETD1A KMT2C SETD1B KMT2D KMT2A | Histone modifications |
  CORUM:6340 | 3.64803730192e-07 | 0.214285714286 | RBBP5 KMT2D ASH2L | PITX2-MLL4-ASH2L-RBBP5-PTIP complex |
  CORUM:5386 | 4.06105934272e-07 | 0.285714285714 | KMT2A RBBP5 HCFC1 ASH2L | MLL1-WDR5 complex |
  CORUM:1254 | 1.27537161256e-06 | 0.214285714286 | RBBP5 DPY30 ASH2L | Menin-associated histone methyltransferase complex |
  GO:0006325 | 2.21490766426e-06 | 0.642857142857 | HCFC1 SETD1A KDM6A KMT2D KMT2A ASH2L HCFC2 DPY30 RBBP5 | chromatin organization |
  GO:0140938 | 5.76255972408e-06 | 0.357142857143 | SETD1A KMT2C SETD1B KMT2D KMT2A | histone H3 methyltransferase activity |
  GO:0071824 | 8.21071816215e-06 | 0.642857142857 | HCFC1 SETD1A KDM6A KMT2D KMT2A ASH2L HCFC2 DPY30 RBBP5 | protein-DNA complex organization |
  HP:0007655 | 1.48631764984e-05 | 0.214285714286 | KMT2A KMT2D KDM6A | Eversion of lateral third of lower eyelids |
  CORUM:2721 | 2.03024740069e-05 | 0.214285714286 | SETD1A HCFC1 ASH2L | HCF-1 complex |
  GO:0042054 | 2.41950677993e-05 | 0.357142857143 | SETD1A KMT2C SETD1B KMT2D KMT2A | histone methyltransferase activity |
  GO:0016279 | 2.70615088402e-05 | 0.357142857143 | SETD1A KMT2C SETD1B KMT2D KMT2A | protein-lysine N-methyltransferase activity |
  GO:0016278 | 3.0192659962e-05 | 0.357142857143 | SETD1A KMT2C SETD1B KMT2D KMT2A | lysine N-methyltransferase activity |
  GO:0006338 | 3.59814526638e-05 | 0.571428571429 | HCFC1 HCFC2 KMT2D KDM6A KMT2A ASH2L DPY30 RBBP5 | chromatin remodeling |
  CORUM:7367 | 0.000133349500201 | 0.142857142857 | ASH2L RBBP5 | ASH2L-KDM6B-KDM6B-WDR5 complex |
  CORUM:6850 | 0.000133349500201 | 0.142857142857 | ASH2L RBBP5 | WRA complex (WDR5, RBBP5, ASH2L) |
  GO:0005654 | 0.000158646533984 | 1.0 | BOD1L1 HCFC1 SETD1A KMT2C CXXC1 KMT2D KMT2A RBBP5 ASH2L HCFC2 BOD1 DPY30 SETD1B KDM6A | nucleoplasm |
  GO:0140993 | 0.000244761795036 | 0.428571428571 | SETD1A KDM6A KMT2D KMT2A KMT2C SETD1B | histone modifying activity |
  KEGG:04934 | 0.000265695773703 | 0.285714285714 | KMT2A RBBP5 KMT2D ASH2L | Cushing syndrome |
  CORUM:6845 | 0.000266552996475 | 0.142857142857 | ASH2L RBBP5 | NIF1-ASH2L-RBBP5-WDR5 complex |
  GO:0008170 | 0.000300130459659 | 0.357142857143 | SETD1A KMT2C SETD1B KMT2D KMT2A | N-methyltransferase activity |
  REAC:R-HSA-212436 | 0.000328326678166 | 0.571428571429 | SETD1A KMT2D SETD1B KMT2A ASH2L KMT2C DPY30 RBBP5 | Generic Transcription Pathway |
  GO:0008276 | 0.000366542378314 | 0.357142857143 | SETD1A KMT2C SETD1B KMT2D KMT2A | protein methyltransferase activity |
  GO:0031981 | 0.000392018703376 | 1.0 | BOD1L1 HCFC1 SETD1A KMT2C CXXC1 KMT2D KMT2A RBBP5 ASH2L HCFC2 BOD1 DPY30 SETD1B KDM6A | nuclear lumen |
  REAC:R-HSA-73857 | 0.000756944497691 | 0.571428571429 | SETD1A KMT2D SETD1B KMT2A ASH2L KMT2C DPY30 RBBP5 | RNA Polymerase II Transcription |
  GO:0045815 | 0.000932727983935 | 0.285714285714 | KMT2A RBBP5 DPY30 ASH2L | transcription initiation-coupled chromatin remodeling |
  GO:0141137 | 0.00106079842337 | 0.285714285714 | KMT2A RBBP5 DPY30 ASH2L | positive regulation of gene expression, epigenetic |
  REAC:R-HSA-3769402 | 0.00137751806588 | 0.214285714286 | RBBP5 KMT2D ASH2L | Deactivation of the beta-catenin transactivating complex |
  HP:0002000 | 0.00148893710822 | 0.214285714286 | KMT2A KMT2D KDM6A | Short columella |
  REAC:R-HSA-1266738 | 0.00152311837204 | 0.5 | KMT2C KMT2D KDM6A KMT2A ASH2L DPY30 RBBP5 | Developmental Biology |
  HP:0000437 | 0.00169101834969 | 0.214285714286 | KMT2A KMT2D KDM6A | Depressed nasal tip |
  GO:0008757 | 0.00447662055434 | 0.357142857143 | SETD1A KMT2C SETD1B KMT2D KMT2A | S-adenosylmethionine-dependent methyltransferase activity |
  HP:0000695 | 0.00478493776584 | 0.214285714286 | KMT2C KMT2D KDM6A | Natal tooth |
  HP:0010447 | 0.0054331440558 | 0.142857142857 | KMT2D KDM6A | Anal fistula |
  HP:0005218 | 0.0054331440558 | 0.142857142857 | KMT2D KDM6A | Anoperineal fistula |
  GO:0070013 | 0.00798042960806 | 1.0 | BOD1L1 HCFC1 SETD1A KMT2C CXXC1 KMT2D KMT2A RBBP5 ASH2L HCFC2 BOD1 DPY30 SETD1B KDM6A | intracellular organelle lumen |
  GO:0031974 | 0.00798042960806 | 1.0 | BOD1L1 HCFC1 SETD1A KMT2C CXXC1 KMT2D KMT2A RBBP5 ASH2L HCFC2 BOD1 DPY30 SETD1B KDM6A | membrane-enclosed lumen |
  GO:0043233 | 0.00798042960806 | 1.0 | BOD1L1 HCFC1 SETD1A KMT2C CXXC1 KMT2D KMT2A RBBP5 ASH2L HCFC2 BOD1 DPY30 SETD1B KDM6A | organelle lumen |
  HP:0006288 | 0.00835969814819 | 0.214285714286 | KMT2C KMT2D KDM6A | Advanced eruption of teeth |
  HP:0011298 | 0.00835969814819 | 0.214285714286 | KMT2A KMT2D KDM6A | Prominent digit pad |
  HP:0005819 | 0.0089815982456 | 0.214285714286 | KMT2A KMT2D KDM6A | Short middle phalanx of finger |
  GO:0008168 | 0.00925573026445 | 0.357142857143 | SETD1A KMT2C SETD1B KMT2D KMT2A | methyltransferase activity |
  GO:0032991 | 0.00969883650892 | 1.0 | BOD1L1 HCFC1 SETD1A KMT2C CXXC1 KMT2D KMT2A RBBP5 ASH2L HCFC2 BOD1 DPY30 SETD1B KDM6A | protein-containing complex |
  GO:0016741 | 0.0124249994516 | 0.357142857143 | SETD1A KMT2C SETD1B KMT2D KMT2A | transferase activity, transferring one-carbon groups |
  HP:0009843 | 0.0133633239712 | 0.214285714286 | KMT2A KMT2D KDM6A | Aplasia/Hypoplasia of the middle phalanges of the hand |
  REAC:R-HSA-201722 | 0.0137894904107 | 0.214285714286 | RBBP5 KMT2D ASH2L | Formation of the beta-catenin:TCF transactivating complex |
  HP:0009237 | 0.0142082692766 | 0.214285714286 | KMT2A KMT2D KDM6A | Short 5th finger |
  GO:0040029 | 0.0149770666387 | 0.357142857143 | ASH2L KMT2A RBBP5 KMT2D DPY30 | epigenetic regulation of gene expression |
  HP:0006262 | 0.0160024485897 | 0.214285714286 | KMT2A KMT2D KDM6A | Aplasia/Hypoplasia of the 5th finger |
  CORUM:1257 | 0.0165736323548 | 0.142857142857 | KMT2A RBBP5 | ALL-1 supercomplex |
  HP:0009833 | 0.0200265187635 | 0.214285714286 | KMT2A KMT2D KDM6A | Abnormal middle phalanx morphology of the hand |
  HP:0000656 | 0.023446571976 | 0.214285714286 | KMT2A KMT2D KDM6A | Ectropion |
  HP:0000637 | 0.0259278542726 | 0.214285714286 | KMT2A KMT2D KDM6A | Long palpebral fissure |
  HP:0010314 | 0.0325097356017 | 0.142857142857 | KMT2D KDM6A | Premature thelarche |
  HP:0004871 | 0.0325097356017 | 0.142857142857 | KMT2D KDM6A | Perineal fistula |
  HP:0008050 | 0.0432198603049 | 0.428571428571 | SETD1A KDM6A KMT2D KMT2A KMT2C SETD1B | Abnormality of the palpebral fissures |
  GO:0042393 | 0.0490014689508 | 0.357142857143 | KMT2A RBBP5 CXXC1 KMT2C KMT2D | histone binding |
  HP:0100267 | 0.0496132916372 | 0.142857142857 | KMT2D KDM6A | Lip pit |
  HP:0004736 | 0.0496132916372 | 0.142857142857 | KMT2D KDM6A | Crossed fused renal ectopia |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD |
---|---|---|---|
 RBBP5 |  ASH2L | 1.0 | 0.438           |
 CXXC1 |  RBBP5 | 1.0 | 0.27           |
 RBBP5 |  SETD1A | 1.0 | 0.208           |
 SETD1B |  RBBP5 | 1.0 | 0.106           |
 CXXC1 |  SETD1A | 1.0 | 0.46           |
 KMT2A |  HCFC2 | 1.0 | 0.144           |
 CXXC1 |  ASH2L | 1.0 | 0.474           |
 CXXC1 |  SETD1B | 1.0 | 0.236           |
 HCFC2 |  ASH2L | 0.999 | 0.276           |
 CXXC1 |  BOD1L1 | 0.999 | 0.256           |
 HCFC2 |  HCFC1 | 0.999 | 0.196           |
 HCFC2 |  SETD1A | 0.999 | 0.462           |
 SETD1B |  ASH2L | 0.999 | 0.22           |
 BOD1L1 |  SETD1A | 0.999 | 0.392           |
 BOD1L1 |  HCFC2 | 0.999 | 0.188           |
 CXXC1 |  HCFC2 | 0.999 | 0.306           |
 SETD1A |  ASH2L | 0.999 | 0.566           |
 CXXC1 |  BOD1 | 0.999 | 0.128           |
 KMT2A |  RBBP5 | 0.999 | 0.156           |
 BOD1L1 |  RBBP5 | 0.999 | 0.324           |
 BOD1 |  ASH2L | 0.999 | 0.182           |
 CXXC1 |  HCFC1 | 0.999 | 0.274           |
 RBBP5 |  KMT2D | 0.998 | 0.11           |
 RBBP5 |  BOD1 | 0.998 | 0.134           |
 DPY30 |  RBBP5 | 0.998 | 0.466           |
 BOD1L1 |  ASH2L | 0.998 | 0.386           |
 KMT2A |  ASH2L | 0.997 | 0.196           |
 CXXC1 |  DPY30 | 0.997 | 0.234           |
 DPY30 |  ASH2L | 0.997 | 0.414           |
 SETD1B |  BOD1 | 0.996 | 0.166           |
 HCFC2 |  RBBP5 | 0.996 | 0.348           |
 HCFC1 |  SETD1A | 0.994 | 0.448           |
 BOD1L1 |  HCFC1 | 0.993 | 0.138           |
 KDM6A |  RBBP5 | 0.993 | 0.316           |
 HCFC1 |  ASH2L | 0.992 | 0.168           |
 HCFC1 |  RBBP5 | 0.989 | 0.068           |
 KDM6A |  KMT2D | 0.983 | 0.192           |
 BOD1L1 |  KDM6A | 0.98 | 0.15           |
 ASH2L |  KMT2D | 0.978 | 0.09203125           |
 SETD1B |  KDM6A | 0.976 | 0.28           |
 KMT2A |  KDM6A | 0.976 | 0.284           |
 KDM6A |  ASH2L | 0.973 | 0.204           |
 RBBP5 |  KMT2C | 0.972 | 0.094           |
 KMT2A |  KMT2D | 0.969 | 0.118           |
 BOD1L1 |  KMT2D | 0.968 | 0.098           |
 SETD1B |  KMT2D | 0.966 | 0.124           |
 CXXC1 |  KMT2A | 0.962 | 0.196           |
 SETD1B |  SETD1A | 0.96 | 0.304           |
 KMT2C |  ASH2L | 0.955 | 0.082           |
 BOD1L1 |  BOD1 | 0.955 | 0.132           |
 SETD1A |  KMT2D | 0.95 | 0.102           |
 BOD1L1 |  KMT2A | 0.947 | 0.18           |
 SETD1B |  KMT2A | 0.946 | 0.222           |
 HCFC2 |  DPY30 | 0.945 | 0.34           |
 BOD1L1 |  SETD1B | 0.945 | 0.196           |
 CXXC1 |  KDM6A | 0.943 | 0.208           |
 KMT2A |  SETD1A | 0.941 | 0.204           |
 BOD1 |  SETD1A | 0.94 | 0.062           |
 SETD1B |  HCFC1 | 0.94 | 0.14           |
 KDM6A |  SETD1A | 0.93 | 0.228           |
 CXXC1 |  KMT2D | 0.922 | 0.218           |
 KDM6A |  HCFC1 | 0.853 | 0.12           |
 SETD1B |  HCFC2 | 0.842 | 0.154           |
 KMT2A |  HCFC1 | 0.825 | 0.09           |
 KDM6A |  DPY30 | 0.824 | 0.212           |
 KDM6A |  BOD1 | 0.798 | 0.152           |
 BOD1 |  KMT2D | 0.798 | 0.134           |
 HCFC2 |  KDM6A | 0.769 | 0.22           |
 HCFC1 |  BOD1 | 0.705 | 0.226           |
 DPY30 |  BOD1 | 0.673 | 0.104           |
 DPY30 |  SETD1A | 0.606 | 0.154           |
 DPY30 |  KMT2D | 0.589 | 0.184           |
 BOD1L1 |  DPY30 | 0.499 | 0.362           |
 SETD1B |  DPY30 | 0.452 | 0.212           |
 HCFC2 |  KMT2D | 0.449 | 0.08           |
 HCFC1 |  KMT2D | 0.381 | 0.088           |
 KMT2A |  BOD1 | 0.373 | 0.15           |
 KMT2A |  DPY30 | 0.362 | 0.078           |
 HCFC2 |  BOD1 | 0.276 | 0.236           |
 KDM6A |  KMT2C | 0.266 | 0.166           |
 HCFC1 |  DPY30 | 0.193 | 0.164           |
 KMT2C |  KMT2D | 0.099 | 0.046           |
 KMT2C |  SETD1A | 0.095 | 0.144           |
 CXXC1 |  KMT2C | 0.095 | 0.144           |
 HCFC2 |  KMT2C | 0.082 | 0.112           |
 KMT2C |  BOD1 | 0.079 | 0.096           |
 SETD1B |  KMT2C | 0.079 | 0.104           |
 BOD1L1 |  KMT2C | 0.079 | 0.096           |
 DPY30 |  KMT2C | 0.078 | 0.1           |
 KMT2A |  KMT2C | 0.071 | 0.07           |
 HCFC1 |  KMT2C | 0.024 | 0.19           |
Related Complexes