hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08932.1
Complex Portal: CPX-11490
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DPEP3 | Dipeptidase 3 | 4 | UniProt NCBI |
| DPEP2 | Dipeptidase 2 (EC 3.4.13.19) | 5 | UniProt NCBI |
| ERP29 | Endoplasmic reticulum resident protein 29 (ERp29) (Endoplasmic reticulum resident protein 28) (ERp28) (Endoplasmic reticulum resident protein 31) (ERp31) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9664535 | 1.70876175213e-05 | 1.0 | DPEP3 DPEP2 | LTC4-CYSLTR mediated IL4 production |
| REAC:R-HSA-5423646 | 0.00023239159829 | 1.0 | DPEP3 DPEP2 | Aflatoxin activation and detoxification |
| REAC:R-HSA-2142691 | 0.000261440548076 | 1.0 | DPEP3 DPEP2 | Synthesis of Leukotrienes (LT) and Eoxins (EX) |
| REAC:R-HSA-2142753 | 0.0019274832564 | 1.0 | DPEP3 DPEP2 | Arachidonic acid metabolism |
| REAC:R-HSA-9662851 | 0.00323126847328 | 1.0 | DPEP3 DPEP2 | Anti-inflammatory response favouring Leishmania parasite infection |
| REAC:R-HSA-9664433 | 0.00323126847328 | 1.0 | DPEP3 DPEP2 | Leishmania parasite growth and survival |
| REAC:R-HSA-9658195 | 0.0156864328845 | 1.0 | DPEP3 DPEP2 | Leishmania infection |
| REAC:R-HSA-9824443 | 0.0156864328845 | 1.0 | DPEP3 DPEP2 | Parasitic Infection Pathways |
| REAC:R-HSA-8978868 | 0.0180872431463 | 1.0 | DPEP3 DPEP2 | Fatty acid metabolism |
| GO:0016805 | 0.0210690324038 | 1.0 | DPEP3 DPEP2 | dipeptidase activity |
| REAC:R-HSA-211859 | 0.0225607814134 | 1.0 | DPEP3 DPEP2 | Biological oxidations |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| DPEP3 | DPEP2 | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| ERP29 | DPEP2 | 0.984 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| DPEP3 | ERP29 | 0.962 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| DPEP3 | huMAP3_01988.1 huMAP3_08932.1 huMAP3_13848.1 |
| DPEP2 | huMAP3_08932.1 |
| ERP29 | huMAP3_01988.1 huMAP3_08932.1 huMAP3_11122.1 huMAP3_13387.1 huMAP3_13721.1 huMAP3_13848.1 |