hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08961.1
Complex Portal: CPX-18538
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| CEBPG | CCAAT/enhancer-binding protein gamma (C/EBP gamma) | 5 | UniProt NCBI |
| CEBPB | CCAAT/enhancer-binding protein beta (C/EBP beta) (Liver activator protein) (LAP) (Liver-enriched inhibitory protein) (LIP) (Nuclear factor NF-IL6) (Transcription factor 5) (TCF-5) | 5 | UniProt NCBI |
| ATF4 | Cyclic AMP-dependent transcription factor ATF-4 (cAMP-dependent transcription factor ATF-4) (Activating transcription factor 4) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2) (Tax-responsive enhancer element-binding protein 67) (TaxREB67) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4211 | 2.34100360042e-05 | 1.0 | CEBPG CEBPB | Transcriptional cascade regulating adipogenesis |
| WP:WP2895 | 8.93837738341e-05 | 1.0 | CEBPG CEBPB | Differentiation of white and brown adipocyte |
| REAC:R-HSA-9648895 | 0.000155497319444 | 1.0 | CEBPG CEBPB | Response of EIF2AK1 (HRI) to heme deficiency |
| REAC:R-HSA-380994 | 0.000555347569442 | 1.0 | CEBPG CEBPB | ATF4 activates genes in response to endoplasmic reticulum stress |
| REAC:R-HSA-381042 | 0.00079457421474 | 1.0 | CEBPG CEBPB | PERK regulates gene expression |
| KEGG:05152 | 0.001720800216 | 1.0 | CEBPG CEBPB | Tuberculosis |
| REAC:R-HSA-381119 | 0.00595674346792 | 1.0 | CEBPG CEBPB | Unfolded Protein Response (UPR) |
| REAC:R-HSA-9633012 | 0.00845837067304 | 1.0 | CEBPG CEBPB | Response of EIF2AK4 (GCN2) to amino acid deficiency |
| REAC:R-HSA-9711097 | 0.0198694816538 | 1.0 | CEBPG CEBPB | Cellular response to starvation |
| WP:WP1589 | 0.0435328773163 | 0.5 | CEBPB | Folate alcohol and cancer pathway hypotheses |
| CORUM:6068 | 0.0499419797295 | 0.5 | CEBPB | ESR1-CEBPB complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ATF4 | CEBPG | 0.981 |
mutually_exclusive (P35638)
structurally_consistent (dimer) |
bioplex3_HEK293 bioplex3_WMM WMM_only | |
| ATF4 | CEBPB | 0.955 |
mutually_exclusive (P53567)
|
bioplex3_HEK293 bioplex3_WMM WMM_only | |
| CEBPB | CEBPG | 0.113 |
structurally_consistent (dimer)
|
bioplex3_WMM WMM_only |
Related Complexes