hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08963.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| THOC5 | THO complex subunit 5 homolog (Functional spliceosome-associated protein 79) (fSAP79) (NF2/meningioma region protein pK1.3) (Placental protein 39.2) (PP39.2) (hTREX90) | 5 | UniProt NCBI |
| CCDC9B | Coiled-coil domain-containing protein 9B | 3 | UniProt NCBI |
| C19orf47 | Uncharacterized protein C19orf47 | 3 | UniProt NCBI |
| KIF1C | Kinesin-like protein KIF1C | 5 | UniProt NCBI |
| THOC1 | THO complex subunit 1 (Tho1) (Nuclear matrix protein p84) (p84N5) (hTREX84) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:774 | 0.000136445626745 | 0.4 | THOC1 THOC5 | THO complex |
| CORUM:6160 | 0.000204640425412 | 0.4 | THOC1 THOC5 | hTREX84 complex |
| CORUM:770 | 0.000286457379015 | 0.4 | THOC1 THOC5 | TREX complex |
| REAC:R-HSA-72187 | 0.0224106525753 | 0.4 | THOC1 THOC5 | mRNA 3'-end processing |
| KEGG:03013 | 0.0226459969921 | 0.4 | THOC1 THOC5 | Nucleocytoplasmic transport |
| REAC:R-HSA-73856 | 0.0294410858888 | 0.4 | THOC1 THOC5 | RNA Polymerase II Transcription Termination |
| REAC:R-HSA-159236 | 0.0363707033179 | 0.4 | THOC1 THOC5 | Transport of Mature mRNA derived from an Intron-Containing Transcript |
| REAC:R-HSA-72202 | 0.0463436196778 | 0.4 | THOC1 THOC5 | Transport of Mature Transcript to Cytoplasm |
| GO:2000002 | 0.0468008499735 | 0.4 | THOC1 THOC5 | negative regulation of DNA damage checkpoint |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| THOC5 | THOC1 | 1.0 | 0.946 | hein_WMM youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM hein () Malo bioplex3_HCT116 fraction |
| KIF1C | THOC1 | 0.992 | 0.068 | hein_WMM bioplex3_WMM hein () |
| KIF1C | C19orf47 | 0.986 | 0.062 | hein_WMM bioplex3_WMM WMM_only |
| CCDC9B | THOC1 | 0.966 | 0.056 | hein_WMM hein () |
| C19orf47 | THOC1 | 0.965 | 0.192 | hein_WMM hein () |
| C19orf47 | THOC5 | 0.963 | 0.242 | hein_WMM hein () |
| KIF1C | THOC5 | 0.803 | 0.072 | hein_WMM bioplex3_WMM hein () |
| C19orf47 | CCDC9B | 0.781 | 0.08 | hein_WMM WMM_only |
| THOC5 | CCDC9B | 0.641 | 0.046 | hein_WMM WMM_only |
| KIF1C | CCDC9B | 0.232 | 0.05 | hein_WMM WMM_only |
Related Complexes