hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_08983.1
Complex Portal: CPX-24851
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PEX10 | Peroxisome biogenesis factor 10 (EC 2.3.2.27) (Peroxin-10) (Peroxisomal biogenesis factor 10) (Peroxisome assembly protein 10) (RING finger protein 69) | 5 | UniProt NCBI |
| MTCL3 | Microtubule cross-linking factor 3 | 3 | UniProt NCBI |
| OSTC | Oligosaccharyltransferase complex subunit OSTC (Hydrophobic protein HSF-28) | 5 | UniProt NCBI |
| SCN3B | Sodium channel regulatory subunit beta-3 | 5 | UniProt NCBI |
| ADH7 | All-trans-retinol dehydrogenase [NAD(+)] ADH7 (EC 1.1.1.105) (Alcohol dehydrogenase class 4 mu/sigma chain) (EC 1.1.1.1) (Alcohol dehydrogenase class IV mu/sigma chain) (Gastric alcohol dehydrogenase) (Omega-hydroxydecanoate dehydrogenase ADH7) (EC 1.1.1.66) (Retinol dehydrogenase) | 5 | UniProt NCBI |
| PEX11B | Peroxisomal membrane protein 11B (Peroxin-11B) (Peroxisomal biogenesis factor 11B) (Protein PEX11 homolog beta) (PEX11-beta) | 5 | UniProt NCBI |
| SLC25A31 | ADP/ATP translocase 4 (ADP,ATP carrier protein 4) (Adenine nucleotide translocator 4) (ANT 4) (Solute carrier family 25 member 31) (Sperm flagellar energy carrier protein) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0001088 | 0.0109736833289 | 0.285714285714 | PEX11B PEX10 | Brushfield spots |
| HP:0010571 | 0.0151234779917 | 0.285714285714 | PEX11B PEX10 | Elevated circulating phytanic acid concentration |
| HP:0010965 | 0.0151234779917 | 0.285714285714 | PEX11B PEX10 | Abnormal circulating phytanic acid concentration |
| HP:0008167 | 0.0174461853129 | 0.285714285714 | PEX11B PEX10 | Very long chain fatty acid accumulation |
| HP:0010964 | 0.0199339480346 | 0.285714285714 | PEX11B PEX10 | Abnormal circulating long-chain fatty-acid concentration |
| KEGG:04146 | 0.0203999615702 | 0.285714285714 | PEX11B PEX10 | Peroxisome |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| SCN3B | ADH7 | 0.997 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PEX10 | SCN3B | 0.992 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| MTCL3 | SCN3B | 0.991 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SCN3B | PEX11B | 0.979 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SCN3B | OSTC | 0.977 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| SCN3B | SLC25A31 | 0.96 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PEX10 | OSTC | 0.287 | 0.092 | bioplex_WMM bioplex3_WMM WMM_only | |
| PEX10 | PEX11B | 0.262 | 0.162 | bioplex_WMM bioplex3_WMM WMM_only | |
| PEX10 | MTCL3 | 0.185 | 0.056 | bioplex_WMM bioplex3_WMM WMM_only | |
| PEX11B | OSTC | 0.165 | 0.186 | bioplex_WMM bioplex3_WMM WMM_only | |
| MTCL3 | PEX11B | 0.162 | 0.094 | bioplex_WMM bioplex3_WMM WMM_only | |
| MTCL3 | OSTC | 0.139 | 0.03 | bioplex_WMM bioplex3_WMM WMM_only | |
| ADH7 | SLC25A31 | 0.074 | bioplex3_WMM WMM_only | ||
| ADH7 | PEX11B | 0.043 | bioplex3_WMM WMM_only | ||
| PEX10 | ADH7 | 0.043 | bioplex3_WMM WMM_only | ||
| MTCL3 | ADH7 | 0.042 | bioplex3_WMM WMM_only | ||
| ADH7 | OSTC | 0.042 | bioplex3_WMM WMM_only | ||
| PEX10 | SLC25A31 | 0.026 | bioplex3_WMM WMM_only | ||
| PEX11B | SLC25A31 | 0.026 | bioplex3_WMM WMM_only | ||
| MTCL3 | SLC25A31 | 0.016 | bioplex3_WMM WMM_only | ||
| SLC25A31 | OSTC | 0.015 | bioplex3_WMM WMM_only |
Related Complexes