hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08985.1
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| INTS9 | Integrator complex subunit 9 (Int9) (Protein related to CPSF subunits of 74 kDa) (RC-74) | 5 | UniProt NCBI |
| INTS4 | Integrator complex subunit 4 (Int4) | 5 | UniProt NCBI |
| INTS5 | Integrator complex subunit 5 (Int5) | 5 | UniProt NCBI |
| INTS6 | Integrator complex subunit 6 (Int6) (DBI-1) (Protein DDX26) (Protein deleted in cancer 1) (DICE1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1154 | 2.37677962583e-11 | 1.0 | INTS9 INTS6 INTS4 INTS5 | DSS1 complex |
| CORUM:1153 | 2.37677962583e-11 | 1.0 | INTS9 INTS6 INTS4 INTS5 | Integrator complex |
| CORUM:1155 | 3.43312612619e-11 | 1.0 | INTS9 INTS6 INTS4 INTS5 | Integrator-RNAPII complex |
| REAC:R-HSA-6807505 | 9.87962469194e-08 | 1.0 | INTS9 INTS6 INTS4 INTS5 | RNA polymerase II transcribes snRNA genes |
| GO:0032039 | 1.01987757791e-07 | 1.0 | INTS9 INTS6 INTS4 INTS5 | integrator complex |
| GO:0016180 | 3.93373833587e-07 | 1.0 | INTS9 INTS6 INTS4 INTS5 | snRNA processing |
| GO:0016073 | 7.12348702995e-06 | 1.0 | INTS9 INTS6 INTS4 INTS5 | snRNA metabolic process |
| GO:0034243 | 3.75329946872e-05 | 1.0 | INTS9 INTS6 INTS4 INTS5 | regulation of transcription elongation by RNA polymerase II |
| GO:0032784 | 8.3767444886e-05 | 1.0 | INTS9 INTS6 INTS4 INTS5 | regulation of DNA-templated transcription elongation |
| GO:0006368 | 9.90506366677e-05 | 1.0 | INTS9 INTS6 INTS4 INTS5 | transcription elongation by RNA polymerase II |
| GO:0006354 | 0.00018840488462 | 1.0 | INTS9 INTS6 INTS4 INTS5 | DNA-templated transcription elongation |
| GO:0034472 | 0.000510886175237 | 0.75 | INTS9 INTS5 INTS6 | snRNA 3'-end processing |
| WP:WP5345 | 0.00578263137464 | 0.5 | INTS9 INTS4 | 1p36 copy number variation syndrome |
| REAC:R-HSA-73857 | 0.00681752083972 | 1.0 | INTS9 INTS6 INTS4 INTS5 | RNA Polymerase II Transcription |
| REAC:R-HSA-74160 | 0.0112707156575 | 1.0 | INTS9 INTS6 INTS4 INTS5 | Gene expression (Transcription) |
| GO:0034470 | 0.0163581002539 | 1.0 | INTS9 INTS6 INTS4 INTS5 | ncRNA processing |
| GO:0031123 | 0.0364824972322 | 0.75 | INTS9 INTS5 INTS6 | RNA 3'-end processing |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| INTS9 | INTS4 | 1.0 | 0.414 | hein_WMM bioplex3_HEK293 bioplex3_WMM youn_WMM hein () Malo bioplex3_HCT116 gupta_WMM fraction |
| INTS5 | INTS4 | 0.998 | 0.906 | hein_WMM bioplex_WMM bioplex3_WMM Malo fraction |
| INTS5 | INTS9 | 0.994 | 0.558 | hein_WMM bioplex3_WMM Malo fraction |
| INTS6 | INTS4 | 0.993 | 0.886 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein () |
| INTS6 | INTS9 | 0.986 | 0.48 | hein_WMM bioplex3_WMM WMM_only |
| INTS5 | INTS6 | 0.968 | 0.874 | hein_WMM bioplex3_WMM WMM_only |
Related Complexes