hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_08991.1
Complex Portal: CPX-11175
Confidence: High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DIAPH2 | Protein diaphanous homolog 2 (Diaphanous-related formin-2) (DRF2) | 5 | UniProt NCBI |
| C1orf198 | Uncharacterized protein C1orf198 | 3 | UniProt NCBI |
| RHOD | Rho-related GTP-binding protein RhoD (Rho-related protein HP1) (RhoHP1) | 5 | UniProt NCBI |
| DAAM1 | Disheveled-associated activator of morphogenesis 1 | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9012999 | 0.0139104893494 | 0.75 | DIAPH2 DAAM1 RHOD | RHO GTPase cycle |
| CORUM:6722 | 0.049938562206 | 0.25 | RHOD | FILIP1-RhoD complex |
| CORUM:6724 | 0.049938562206 | 0.25 | RHOD | WHAMM-RhoD complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| C1orf198 | RHOD | 0.999 | 0.246 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| RHOD | DAAM1 | 0.996 | 0.384 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 |
| RHOD | DIAPH2 | 0.996 | 0.210333333333 |
structurally_consistent (dimer)
|
bioplex3_WMM bioplex3_HCT116 WMM_only |
| C1orf198 | DAAM1 | 0.995 | 0.184 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| C1orf198 | DIAPH2 | 0.715 | 0.086 | bioplex3_WMM WMM_only | |
| DAAM1 | DIAPH2 | 0.267 | 0.078 |
mutually_exclusive (O00212)
|
bioplex3_WMM WMM_only |
Related Complexes