hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09024.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ORC6 | Origin recognition complex subunit 6 | 5 | UniProt NCBI |
| DDX42 | ATP-dependent RNA helicase DDX42 (EC 3.6.4.13) (DEAD box protein 42) (RNA helicase-like protein) (RHELP) (RNA helicase-related protein) (RNAHP) (SF3b DEAD box protein) (Splicing factor 3B-associated 125 kDa protein) (SF3b125) | 5 | UniProt NCBI |
| PSPC1 | Paraspeckle component 1 (Paraspeckle protein 1) | 5 | UniProt NCBI |
| NONO | Non-POU domain-containing octamer-binding protein (NonO protein) (54 kDa nuclear RNA- and DNA-binding protein) (p54(nrb)) (p54nrb) (55 kDa nuclear protein) (NMT55) (DNA-binding p52/p100 complex, 52 kDa subunit) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7285 | 7.68662167609e-05 | 0.5 | PSPC1 NONO | HEXIM1-DNA-PK-paraspeckle components-ribonucleoprotein complex |
| CORUM:330 | 0.0249718442456 | 0.25 | NONO | PSF-p54(nrb) complex |
| CORUM:1760 | 0.0249718442456 | 0.25 | NONO | TOP1-PSF-P54 complex |
| HPA:0570783 | 0.0258977031751 | 0.75 | ORC6 PSPC1 NONO | testis; preleptotene spermatocytes[High] |
| WP:WP3594 | 0.03162086928 | 0.5 | PSPC1 NONO | Circadian rhythm genes |
| HPA:0550053 | 0.0399271079825 | 1.0 | ORC6 NONO PSPC1 DDX42 | stomach 2; glandular cells[High] |
| CORUM:335 | 0.049938562206 | 0.25 | NONO | p54(nrb)-PSF-matrin3 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| PSPC1 | NONO | 1.0 | 0.62 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 fraction boldt_WMM treiber_WMM |
| ORC6 | NONO | 0.972 | 0.22 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| ORC6 | DDX42 | 0.967 | 0.116 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| ORC6 | PSPC1 | 0.957 | 0.092 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
| DDX42 | PSPC1 | 0.674 | 0.224 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| DDX42 | NONO | 0.262 | 0.376 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 treiber_WMM WMM_only |
Related Complexes