hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_09038.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KDM5B | Lysine-specific demethylase 5B (EC 1.14.11.67) (Cancer/testis antigen 31) (CT31) (Histone demethylase JARID1B) (Jumonji/ARID domain-containing protein 1B) (PLU-1) (Retinoblastoma-binding protein 2 homolog 1) (RBP2-H1) ([histone H3]-trimethyl-L-lysine(4) demethylase 5B) | 5 | UniProt NCBI |
| RFPL4A | Ret finger protein-like 4A (RING finger protein 210) | 4 | UniProt NCBI |
| FAM90A1 | Protein FAM90A1 | 5 | UniProt NCBI |
| BRD3 | Bromodomain-containing protein 3 (RING3-like protein) | 5 | UniProt NCBI |
| FAM90A26 | Putative protein FAM90A26 | 2 | UniProt NCBI |
| RFPL4B | Ret finger protein-like 4B (RING finger protein 211) | 2 | UniProt NCBI |
| BRD2 | Bromodomain-containing protein 2 (O27.1.1) | 5 | UniProt NCBI |
| BRD4 | Bromodomain-containing protein 4 (Protein HUNK1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0070577 | 0.00948397324055 | 0.375 | BRD4 BRD3 BRD2 | lysine-acetylated histone binding |
| GO:0140033 | 0.00948397324055 | 0.375 | BRD4 BRD3 BRD2 | acetylation-dependent protein binding |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| RFPL4A | RFPL4B | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| BRD3 | BRD2 | 0.999 | 0.162 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM fraction |
| FAM90A1 | BRD4 | 0.999 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | |
| BRD4 | BRD3 | 0.997 | 0.316 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction |
| FAM90A1 | RFPL4B | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| FAM90A1 | BRD3 | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| FAM90A1 | BRD2 | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| FAM90A1 | RFPL4A | 0.994 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| FAM90A1 | KDM5B | 0.99 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| BRD4 | BRD2 | 0.989 | 0.294 | bioplex_WMM bioplex3_WMM youn_WMM fraction |
| KDM5B | RFPL4A | 0.513 | bioplex_WMM bioplex3_WMM WMM_only | |
| KDM5B | RFPL4B | 0.513 | bioplex_WMM bioplex3_WMM WMM_only | |
| BRD3 | RFPL4B | 0.377 | bioplex_WMM bioplex3_WMM WMM_only | |
| RFPL4A | BRD3 | 0.377 | bioplex_WMM bioplex3_WMM WMM_only | |
| BRD4 | RFPL4B | 0.224 | bioplex_WMM bioplex3_WMM WMM_only | |
| BRD4 | RFPL4A | 0.224 | bioplex_WMM bioplex3_WMM WMM_only | |
| KDM5B | BRD2 | 0.216 | 0.064 | bioplex_WMM bioplex3_WMM WMM_only |
| KDM5B | BRD3 | 0.215 | 0.11 | bioplex_WMM bioplex3_WMM WMM_only |
| BRD4 | KDM5B | 0.215 | 0.134 | bioplex_WMM bioplex3_WMM WMM_only |
| RFPL4B | BRD2 | 0.188 | bioplex_WMM bioplex3_WMM WMM_only | |
| RFPL4A | BRD2 | 0.188 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes