hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_09051.1

Complex Portal: CPX-19677

Confidence: Moderate High

Genename	Protein Name	Uniprot Annotation Score	Links
BOD1L1	Biorientation of chromosomes in cell division protein 1-like 1	5	UniProt NCBI
SETD1A	Histone-lysine N-methyltransferase SETD1A (EC 2.1.1.364) (Lysine N-methyltransferase 2F) (SET domain-containing protein 1A) (hSET1A) (Set1/Ash2 histone methyltransferase complex subunit SET1)	5	UniProt NCBI
SETD1B	Histone-lysine N-methyltransferase SETD1B (EC 2.1.1.364) (Lysine N-methyltransferase 2G) (SET domain-containing protein 1B) (hSET1B)	5	UniProt NCBI
KMT2A	Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.364) (ALL-1) (CXXC-type zinc finger protein 7) (Cysteine methyltransferase KMT2A) (EC 2.1.1.-) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)]	5	UniProt NCBI
NCOA6	Nuclear receptor coactivator 6 (Activating signal cointegrator 2) (ASC-2) (Amplified in breast cancer protein 3) (Cancer-amplified transcriptional coactivator ASC-2) (Nuclear receptor coactivator RAP250) (NRC RAP250) (Nuclear receptor-activating protein, 250 kDa) (Peroxisome proliferator-activated receptor-interacting protein) (PPAR-interacting protein) (PRIP) (Thyroid hormone receptor-binding protein)	5	UniProt NCBI
CXXC1	CXXC-type zinc finger protein 1 (CpG-binding protein) (PHD finger and CXXC domain-containing protein 1)	5	UniProt NCBI
KMT2D	Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.364) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2)	5	UniProt NCBI
KDM6A	Lysine-specific demethylase 6A (EC 1.14.11.68) (Histone demethylase UTX) (Ubiquitously-transcribed TPR protein on the X chromosome) (Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein) ([histone H3]-trimethyl-L-lysine(27) demethylase 6A)	5	UniProt NCBI
HCFC1	Host cell factor 1 (HCF) (HCF-1) (C1 factor) (CFF) (VCAF) (VP16 accessory protein) [Cleaved into: HCF N-terminal chain 1; HCF N-terminal chain 2; HCF N-terminal chain 3; HCF N-terminal chain 4; HCF N-terminal chain 5; HCF N-terminal chain 6; HCF C-terminal chain 1; HCF C-terminal chain 2; HCF C-terminal chain 3; HCF C-terminal chain 4; HCF C-terminal chain 5; HCF C-terminal chain 6]	5	UniProt NCBI
HCFC2	Host cell factor 2 (HCF-2) (C2 factor)	5	UniProt NCBI
DPY30	Protein dpy-30 homolog (Dpy-30-like protein) (Dpy-30L)	5	UniProt NCBI
ASH2L	Set1/Ash2 histone methyltransferase complex subunit ASH2 (ASH2-like protein)	5	UniProt NCBI
ATN1	Atrophin-1 (Dentatorubral-pallidoluysian atrophy protein)	5	UniProt NCBI
RBBP5	Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3)	5	UniProt NCBI
KMT2C	Histone-lysine N-methyltransferase 2C (Lysine N-methyltransferase 2C) (EC 2.1.1.364) (Homologous to ALR protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 3)	5	UniProt NCBI
WDR5	WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)	5	UniProt NCBI
BOD1	Biorientation of chromosomes in cell division protein 1 (Biorientation defective protein 1) (Protein FAM44B)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-9772755	1.67548356177e-39	0.941176470588	NCOA6 DPY30 BOD1L1 KMT2A BOD1 SETD1B KMT2D CXXC1 HCFC2 KDM6A WDR5 ASH2L RBBP5 HCFC1 SETD1A KMT2C	Formation of WDR5-containing histone-modifying complexes
GO:0035097	2.01542693008e-33	0.941176470588	NCOA6 DPY30 BOD1L1 KMT2A BOD1 SETD1B KMT2D CXXC1 HCFC2 KDM6A WDR5 ASH2L RBBP5 HCFC1 SETD1A KMT2C	histone methyltransferase complex
GO:0034708	1.07266828887e-30	0.941176470588	NCOA6 DPY30 BOD1L1 KMT2A BOD1 SETD1B KMT2D CXXC1 HCFC2 KDM6A WDR5 ASH2L RBBP5 HCFC1 SETD1A KMT2C	methyltransferase complex
REAC:R-HSA-212165	3.27364809321e-28	0.941176470588	NCOA6 DPY30 BOD1L1 KMT2A BOD1 SETD1B KMT2D CXXC1 HCFC2 KDM6A WDR5 ASH2L RBBP5 HCFC1 SETD1A KMT2C	Epigenetic regulation of gene expression
CORUM:6470	4.48680094585e-28	0.588235294118	HCFC2 BOD1L1 CXXC1 WDR5 BOD1 HCFC1 SETD1B DPY30 RBBP5 ASH2L	Set1B complex
GO:0048188	1.38728069678e-27	0.647058823529	HCFC2 BOD1L1 WDR5 BOD1 HCFC1 SETD1B CXXC1 DPY30 ASH2L RBBP5 SETD1A	Set1C/COMPASS complex
CORUM:6469	9.06291501899e-22	0.470588235294	HCFC2 CXXC1 WDR5 HCFC1 SETD1A DPY30 RBBP5 ASH2L	Set1A complex
CORUM:6461	1.05901976765e-18	0.411764705882	NCOA6 KMT2C WDR5 DPY30 KDM6A RBBP5 ASH2L	MLL3 complex
CORUM:6467	1.05901976765e-18	0.411764705882	NCOA6 WDR5 KMT2D DPY30 KDM6A RBBP5 ASH2L	MLL4 complex
CORUM:5195	3.52795121201e-18	0.411764705882	NCOA6 KMT2C WDR5 DPY30 KDM6A RBBP5 ASH2L	PTIP-HMT complex
CORUM:6460	3.52795121201e-18	0.411764705882	HCFC2 WDR5 HCFC1 KMT2D DPY30 RBBP5 ASH2L	MLL2 complex
GO:0044666	3.88586092507e-18	0.470588235294	NCOA6 KMT2C WDR5 KMT2D DPY30 KDM6A RBBP5 ASH2L	MLL3/4 complex
CORUM:3075	2.32565871516e-17	0.411764705882	NCOA6 KMT2C WDR5 KMT2D KDM6A RBBP5 ASH2L	UTX-MLL2/3 complex
CORUM:6462	1.09382304026e-15	0.352941176471	KMT2A HCFC1 DPY30 WDR5 RBBP5 ASH2L	MLL1 complex
GO:1990234	2.84165338842e-15	0.941176470588	NCOA6 DPY30 BOD1L1 KMT2A BOD1 SETD1B KMT2D CXXC1 HCFC2 KDM6A WDR5 ASH2L RBBP5 HCFC1 SETD1A KMT2C	transferase complex
REAC:R-HSA-3214841	4.48831193407e-15	0.529411764706	KMT2C KMT2A SETD1B KMT2D DPY30 SETD1A WDR5 RBBP5 ASH2L	PKMTs methylate histone lysines
REAC:R-HSA-8936459	2.09958708344e-14	0.529411764706	KMT2C KMT2A SETD1B KMT2D DPY30 SETD1A WDR5 RBBP5 ASH2L	RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
CORUM:6851	4.76232228396e-14	0.294117647059	KMT2A WDR5 ASH2L RBBP5 DPY30	MWRAD complex (MLL1, WDR5, RBBP5, ASH2L, DPY30)
REAC:R-HSA-74160	6.84126795658e-14	0.941176470588	NCOA6 DPY30 BOD1L1 KMT2A BOD1 SETD1B KMT2D CXXC1 HCFC2 KDM6A WDR5 ASH2L RBBP5 HCFC1 SETD1A KMT2C	Gene expression (Transcription)
REAC:R-HSA-4839726	1.07426831606e-13	0.647058823529	KMT2C KMT2A SETD1B HCFC1 SETD1A DPY30 KDM6A WDR5 ASH2L RBBP5 KMT2D	Chromatin organization
REAC:R-HSA-3247509	1.07426831606e-13	0.647058823529	KMT2C KMT2A SETD1B HCFC1 SETD1A DPY30 KDM6A WDR5 ASH2L RBBP5 KMT2D	Chromatin modifying enzymes
WP:WP5351	1.20633818587e-13	0.411764705882	NCOA6 KMT2C WDR5 DPY30 KDM6A RBBP5 ASH2L	Kleefstra syndrome
CORUM:2730	2.8554375912e-13	0.294117647059	CXXC1 WDR5 SETD1B RBBP5 ASH2L	Set1B complex
CORUM:2731	2.8554375912e-13	0.294117647059	CXXC1 WDR5 SETD1A RBBP5 ASH2L	Set1A complex
GO:0140513	8.26611137753e-13	0.941176470588	NCOA6 DPY30 BOD1L1 KMT2A BOD1 SETD1B KMT2D CXXC1 HCFC2 KDM6A WDR5 ASH2L RBBP5 HCFC1 SETD1A KMT2C	nuclear protein-containing complex
CORUM:1400	9.98719075998e-13	0.294117647059	NCOA6 KMT2C KMT2D RBBP5 ASH2L	ASCOM complex
CORUM:1256	9.98719075998e-13	0.294117647059	KMT2A WDR5 HCFC1 RBBP5 ASH2L	MLL-HCF complex
CORUM:1401	1.19600337757e-11	0.294117647059	KMT2A WDR5 SETD1A RBBP5 KMT2D	MOF complex
REAC:R-HSA-5617472	4.3491962918e-11	0.470588235294	NCOA6 KMT2C WDR5 KMT2D DPY30 KDM6A RBBP5 ASH2L	Activation of anterior HOX genes in hindbrain development during early embryogenesis
REAC:R-HSA-5619507	4.3491962918e-11	0.470588235294	NCOA6 KMT2C WDR5 KMT2D DPY30 KDM6A RBBP5 ASH2L	Activation of HOX genes during differentiation
CORUM:6457	5.35248391468e-11	0.235294117647	KMT2A WDR5 ASH2L RBBP5	MLL1 core complex
CORUM:1399	5.35248391468e-11	0.235294117647	RBBP5 WDR5 KMT2D ASH2L	WDR5-ASH2L-RBBP5-MLL2 complex
CORUM:6849	5.35248391468e-11	0.235294117647	DPY30 WDR5 ASH2L RBBP5	WRAD complex (WDR5, RBBP5, ASH2L, DPY30)
GO:0071339	8.9319152099e-11	0.411764705882	HCFC2 KMT2A HCFC1 DPY30 WDR5 RBBP5 ASH2L	MLL1 complex
GO:0044665	1.14259948973e-10	0.411764705882	HCFC2 KMT2A HCFC1 DPY30 WDR5 RBBP5 ASH2L	MLL1/2 complex
GO:1902494	1.45684835396e-10	0.941176470588	NCOA6 DPY30 BOD1L1 KMT2A BOD1 SETD1B KMT2D CXXC1 HCFC2 KDM6A WDR5 ASH2L RBBP5 HCFC1 SETD1A KMT2C	catalytic complex
REAC:R-HSA-8878171	1.63014578726e-10	0.529411764706	KMT2C KMT2A SETD1B KMT2D DPY30 SETD1A WDR5 RBBP5 ASH2L	Transcriptional regulation by RUNX1
CORUM:1254	1.86937175692e-09	0.235294117647	DPY30 WDR5 ASH2L RBBP5	Menin-associated histone methyltransferase complex
CORUM:5386	3.08791720249e-09	0.294117647059	KMT2A WDR5 HCFC1 RBBP5 ASH2L	MLL1-WDR5 complex
GO:0042800	2.56367096242e-08	0.294117647059	KMT2A KMT2C KMT2D SETD1A SETD1B	histone H3K4 methyltransferase activity
CORUM:7367	5.58646392581e-08	0.176470588235	RBBP5 ASH2L WDR5	ASH2L-KDM6B-KDM6B-WDR5 complex
CORUM:6850	5.58646392581e-08	0.176470588235	RBBP5 ASH2L WDR5	WRA complex (WDR5, RBBP5, ASH2L)
CORUM:2721	9.6586259944e-08	0.235294117647	ASH2L WDR5 SETD1A HCFC1	HCF-1 complex
CORUM:6845	2.23297982515e-07	0.176470588235	RBBP5 ASH2L WDR5	NIF1-ASH2L-RBBP5-WDR5 complex
KEGG:00310	2.96988814e-07	0.294117647059	KMT2A KMT2C KMT2D SETD1A SETD1B	Lysine degradation
CORUM:6340	5.57843805733e-07	0.176470588235	RBBP5 KMT2D ASH2L	PITX2-MLL4-ASH2L-RBBP5-PTIP complex
GO:0006325	6.20446841574e-07	0.588235294118	HCFC2 KMT2A HCFC1 KMT2D DPY30 KDM6A WDR5 ASH2L RBBP5 SETD1A	chromatin organization
WP:WP2369	7.88053002193e-07	0.294117647059	KMT2A KMT2C KMT2D SETD1A SETD1B	Histone modifications
GO:0005654	2.38233655669e-06	1.0	NCOA6 DPY30 BOD1L1 KMT2A BOD1 WDR5 SETD1B KMT2D CXXC1 HCFC2 KDM6A ATN1 ASH2L RBBP5 HCFC1 SETD1A KMT2C	nucleoplasm
GO:0071824	2.64616598682e-06	0.588235294118	HCFC2 KMT2A HCFC1 KMT2D DPY30 KDM6A WDR5 ASH2L RBBP5 SETD1A	protein-DNA complex organization
GO:0031981	7.14923127494e-06	1.0	NCOA6 DPY30 BOD1L1 KMT2A BOD1 WDR5 SETD1B KMT2D CXXC1 HCFC2 KDM6A ATN1 ASH2L RBBP5 HCFC1 SETD1A KMT2C	nuclear lumen
GO:0006338	7.38016414754e-06	0.529411764706	HCFC2 KMT2A HCFC1 ASH2L DPY30 KDM6A WDR5 RBBP5 KMT2D	chromatin remodeling
GO:0045815	1.10148744105e-05	0.294117647059	KMT2A WDR5 ASH2L RBBP5 DPY30	transcription initiation-coupled chromatin remodeling
GO:0141137	1.29729213266e-05	0.294117647059	KMT2A WDR5 ASH2L RBBP5 DPY30	positive regulation of gene expression, epigenetic
KEGG:04934	1.45172639836e-05	0.294117647059	KMT2A WDR5 KMT2D RBBP5 ASH2L	Cushing syndrome
GO:0140938	1.77202608399e-05	0.294117647059	KMT2A KMT2C KMT2D SETD1A SETD1B	histone H3 methyltransferase activity
HP:0007655	2.83568800281e-05	0.176470588235	KMT2A KMT2D KDM6A	Eversion of lateral third of lower eyelids
REAC:R-HSA-1266738	3.90490517573e-05	0.529411764706	NCOA6 KMT2C KMT2A KMT2D DPY30 KDM6A WDR5 RBBP5 ASH2L	Developmental Biology
GO:0042054	7.42613550103e-05	0.294117647059	KMT2A KMT2C KMT2D SETD1A SETD1B	histone methyltransferase activity
GO:0016279	8.30450212052e-05	0.294117647059	KMT2A KMT2C KMT2D SETD1A SETD1B	protein-lysine N-methyltransferase activity
GO:0016278	9.26378642656e-05	0.294117647059	KMT2A KMT2C KMT2D SETD1A SETD1B	lysine N-methyltransferase activity
HP:0011298	0.000148310857076	0.235294117647	KMT2A KMT2D ATN1 KDM6A	Prominent digit pad
CORUM:1257	0.000179752730585	0.176470588235	KMT2A WDR5 RBBP5	ALL-1 supercomplex
REAC:R-HSA-212436	0.00018595814506	0.529411764706	KMT2C KMT2A SETD1B KMT2D DPY30 SETD1A WDR5 RBBP5 ASH2L	Generic Transcription Pathway
GO:0031974	0.000277956239225	1.0	NCOA6 DPY30 BOD1L1 KMT2A BOD1 WDR5 SETD1B KMT2D CXXC1 HCFC2 KDM6A ATN1 ASH2L RBBP5 HCFC1 SETD1A KMT2C	membrane-enclosed lumen
GO:0070013	0.000277956239225	1.0	NCOA6 DPY30 BOD1L1 KMT2A BOD1 WDR5 SETD1B KMT2D CXXC1 HCFC2 KDM6A ATN1 ASH2L RBBP5 HCFC1 SETD1A KMT2C	intracellular organelle lumen
GO:0043233	0.000277956239225	1.0	NCOA6 DPY30 BOD1L1 KMT2A BOD1 WDR5 SETD1B KMT2D CXXC1 HCFC2 KDM6A ATN1 ASH2L RBBP5 HCFC1 SETD1A KMT2C	organelle lumen
GO:0006352	0.000466375816752	0.352941176471	NCOA6 KMT2A DPY30 WDR5 RBBP5 ASH2L	DNA-templated transcription initiation
REAC:R-HSA-73857	0.000471183913822	0.529411764706	KMT2C KMT2A SETD1B KMT2D DPY30 SETD1A WDR5 RBBP5 ASH2L	RNA Polymerase II Transcription
GO:0008170	0.000916614703515	0.294117647059	KMT2A KMT2C KMT2D SETD1A SETD1B	N-methyltransferase activity
GO:0140993	0.000981129153213	0.352941176471	KMT2C KMT2A SETD1B SETD1A KDM6A KMT2D	histone modifying activity
GO:0040029	0.000981129153213	0.352941176471	KMT2A KMT2D DPY30 WDR5 RBBP5 ASH2L	epigenetic regulation of gene expression
GO:0008276	0.00111886446464	0.294117647059	KMT2A KMT2C KMT2D SETD1A SETD1B	protein methyltransferase activity
CORUM:7221	0.00194987488536	0.117647058824	WDR5 HCFC1	NSL complex
HP:0009929	0.00225238343015	0.235294117647	KMT2A KMT2D ATN1 KDM6A	Abnormal columella morphology
HP:0002000	0.00283282072605	0.176470588235	KMT2A KMT2D KDM6A	Short columella
REAC:R-HSA-3769402	0.0029402616731	0.176470588235	RBBP5 KMT2D ASH2L	Deactivation of the beta-catenin transactivating complex
HP:0000437	0.00321680092289	0.176470588235	KMT2A KMT2D KDM6A	Depressed nasal tip
GO:0005634	0.0039044938527	1.0	NCOA6 DPY30 BOD1L1 KMT2A BOD1 WDR5 SETD1B KMT2D CXXC1 HCFC2 KDM6A ATN1 ASH2L RBBP5 HCFC1 SETD1A KMT2C	nucleus
GO:0042393	0.00407993401879	0.352941176471	KMT2C KMT2A CXXC1 WDR5 RBBP5 KMT2D	histone binding
KEGG:03083	0.00636007547024	0.176470588235	HCFC2 HCFC1 WDR5	Polycomb repressive complex
GO:0006367	0.00828137951251	0.294117647059	KMT2A WDR5 ASH2L RBBP5 DPY30	transcription initiation at RNA polymerase II promoter
HP:0010447	0.00829411048776	0.117647058824	KMT2D KDM6A	Anal fistula
HP:0005218	0.00829411048776	0.117647058824	KMT2D KDM6A	Anoperineal fistula
HP:0000695	0.00908831863398	0.176470588235	KMT2C KMT2D KDM6A	Natal tooth
GO:0032991	0.0124488967374	0.941176470588	NCOA6 DPY30 BOD1L1 KMT2A BOD1 SETD1B KMT2D CXXC1 HCFC2 KDM6A WDR5 ASH2L RBBP5 HCFC1 SETD1A KMT2C	protein-containing complex
GO:0008757	0.0135480545829	0.294117647059	KMT2A KMT2C KMT2D SETD1A SETD1B	S-adenosylmethionine-dependent methyltransferase activity
HP:0001212	0.0136700321709	0.176470588235	ATN1 KMT2D KDM6A	Prominent fingertip pads
HP:0006288	0.0158609773735	0.176470588235	KMT2C KMT2D KDM6A	Advanced eruption of teeth
MIRNA:hsa-miR-4758-3p	0.0163838770872	0.235294117647	WDR5 BOD1 SETD1A KMT2D	hsa-miR-4758-3p
HP:0005819	0.017038295248	0.176470588235	KMT2A KMT2D KDM6A	Short middle phalanx of finger
HP:0009843	0.0253271341367	0.176470588235	KMT2A KMT2D KDM6A	Aplasia/Hypoplasia of the middle phalanges of the hand
HP:0009237	0.0269243925091	0.176470588235	KMT2A KMT2D KDM6A	Short 5th finger
GO:0008168	0.0279155042139	0.294117647059	KMT2A KMT2C KMT2D SETD1A SETD1B	methyltransferase activity
REAC:R-HSA-201722	0.0292481187875	0.176470588235	RBBP5 KMT2D ASH2L	Formation of the beta-catenin:TCF transactivating complex
HP:0006262	0.0303149978899	0.176470588235	KMT2A KMT2D KDM6A	Aplasia/Hypoplasia of the 5th finger
GO:0006366	0.0314414576294	0.647058823529	HCFC2 KMT2C NCOA6 KMT2A WDR5 HCFC1 ASH2L DPY30 ATN1 RBBP5 KMT2D	transcription by RNA polymerase II
HP:0000403	0.0361333111504	0.235294117647	KMT2A KMT2D ATN1 KDM6A	Recurrent otitis media
GO:0016741	0.0374161934089	0.294117647059	KMT2A KMT2C KMT2D SETD1A SETD1B	transferase activity, transferring one-carbon groups
HP:0009833	0.0379148485456	0.176470588235	KMT2A KMT2D KDM6A	Abnormal middle phalanx morphology of the hand
HP:0000656	0.0443693241485	0.176470588235	KMT2A KMT2D KDM6A	Ectropion
HP:0000637	0.0490497098243	0.176470588235	KMT2A KMT2D KDM6A	Long palpebral fissure
HP:0004871	0.0495946438232	0.117647058824	KMT2D KDM6A	Perineal fistula
HP:0010314	0.0495946438232	0.117647058824	KMT2D KDM6A	Premature thelarche

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
RBBP5	ASH2L	1.0	0.438	structurally_consistent (dimer)
CXXC1	RBBP5	1.0	0.27	structurally_consistent (dimer)
RBBP5	SETD1A	1.0	0.208	mutually_exclusive (P61964)
SETD1B	RBBP5	1.0	0.106
CXXC1	SETD1A	1.0	0.46
KMT2A	HCFC2	1.0	0.144
WDR5	RBBP5	1.0	0.574	structurally_consistent (dimer)
CXXC1	WDR5	1.0	0.464	structurally_consistent (dimer)
CXXC1	ASH2L	1.0	0.474	structurally_consistent (Q15291)
CXXC1	SETD1B	1.0	0.236
HCFC2	ASH2L	0.999	0.276
CXXC1	BOD1L1	0.999	0.256
HCFC2	HCFC1	0.999	0.196
HCFC2	SETD1A	0.999	0.462
SETD1B	ASH2L	0.999	0.22
BOD1L1	SETD1A	0.999	0.392
BOD1L1	HCFC2	0.999	0.188
CXXC1	HCFC2	0.999	0.306
SETD1A	ASH2L	0.999	0.566
CXXC1	BOD1	0.999	0.128
KMT2A	RBBP5	0.999	0.156
BOD1L1	RBBP5	0.999	0.324
WDR5	BOD1L1	0.999	0.198
BOD1	ASH2L	0.999	0.182
CXXC1	HCFC1	0.999	0.274
WDR5	ASH2L	0.998	0.236	structurally_consistent (Q15291)
RBBP5	KMT2D	0.998	0.11
WDR5	SETD1A	0.998	0.168	structurally_consistent (dimer)
RBBP5	BOD1	0.998	0.134
DPY30	RBBP5	0.998	0.466
BOD1L1	ASH2L	0.998	0.386
KMT2A	ASH2L	0.997	0.196
CXXC1	DPY30	0.997	0.234	structurally_consistent (P61964)
DPY30	ASH2L	0.997	0.414
SETD1B	BOD1	0.996	0.166
HCFC2	RBBP5	0.996	0.348
WDR5	KMT2A	0.996	0.228
ATN1	WDR5	0.994	0.142	structurally_consistent (dimer)
HCFC1	SETD1A	0.994	0.448
BOD1L1	HCFC1	0.993	0.138
WDR5	SETD1B	0.993	0.172
KDM6A	RBBP5	0.993	0.316	mutually_exclusive (P61964)
WDR5	HCFC1	0.992	0.14
HCFC1	ASH2L	0.992	0.168
HCFC1	RBBP5	0.989	0.068
WDR5	HCFC2	0.988	0.192
NCOA6	WDR5	0.984	0.352
KDM6A	KMT2D	0.983	0.192
WDR5	KMT2D	0.982	0.0641691542289
WDR5	KDM6A	0.981	0.312	structurally_consistent (dimer)
BOD1L1	KDM6A	0.98	0.15
ASH2L	KMT2D	0.978	0.09203125
SETD1B	KDM6A	0.976	0.28
KMT2A	KDM6A	0.976	0.284
WDR5	DPY30	0.973	0.3825	structurally_consistent (dimer)
KDM6A	ASH2L	0.973	0.204
RBBP5	KMT2C	0.972	0.094
KMT2A	KMT2D	0.969	0.118
BOD1L1	KMT2D	0.968	0.098
SETD1B	KMT2D	0.966	0.124
ATN1	RBBP5	0.964	0.12	mutually_exclusive (P61964)
WDR5	BOD1	0.962	0.222
CXXC1	KMT2A	0.962	0.196
SETD1B	SETD1A	0.96	0.304
KMT2C	ASH2L	0.955	0.082
BOD1L1	BOD1	0.955	0.132
SETD1A	KMT2D	0.95	0.102
BOD1L1	KMT2A	0.947	0.18
SETD1B	KMT2A	0.946	0.222
HCFC2	DPY30	0.945	0.34
BOD1L1	SETD1B	0.945	0.196
CXXC1	KDM6A	0.943	0.208
KMT2A	SETD1A	0.941	0.204
BOD1	SETD1A	0.94	0.062
SETD1B	HCFC1	0.94	0.14
KDM6A	SETD1A	0.93	0.228
CXXC1	KMT2D	0.922	0.218
ATN1	SETD1A	0.92	0.15	mutually_exclusive (P61964)
CXXC1	ATN1	0.902	0.316
KDM6A	HCFC1	0.853	0.12
SETD1B	HCFC2	0.842	0.154
NCOA6	ASH2L	0.835	0.318
KMT2A	HCFC1	0.825	0.09
KDM6A	DPY30	0.824	0.212
ATN1	ASH2L	0.811	0.194
NCOA6	RBBP5	0.805	0.346
NCOA6	BOD1	0.798	0.134
KDM6A	BOD1	0.798	0.152
BOD1	KMT2D	0.798	0.134
NCOA6	SETD1B	0.791	0.192
HCFC2	KDM6A	0.769	0.22
NCOA6	KMT2D	0.759	0.118
ATN1	KMT2A	0.712	0.152
HCFC1	BOD1	0.705	0.226
DPY30	BOD1	0.673	0.104
ATN1	HCFC1	0.672	0.126
NCOA6	KDM6A	0.671	0.268
NCOA6	BOD1L1	0.641	0.242
DPY30	SETD1A	0.606	0.154
ATN1	HCFC2	0.592	0.218
DPY30	KMT2D	0.589	0.184
NCOA6	KMT2A	0.533	0.14
BOD1L1	DPY30	0.499	0.362
CXXC1	NCOA6	0.469	0.216
SETD1B	DPY30	0.452	0.212
HCFC2	KMT2D	0.449	0.08
ATN1	BOD1L1	0.431	0.186
NCOA6	ATN1	0.417	0.296
ATN1	SETD1B	0.401	0.318
ATN1	KMT2D	0.4	0.152
NCOA6	SETD1A	0.398	0.206
ATN1	KDM6A	0.389	0.226
HCFC1	KMT2D	0.381	0.088
KMT2A	BOD1	0.373	0.15
KMT2A	DPY30	0.362	0.078
ATN1	BOD1	0.357	0.098
NCOA6	HCFC2	0.293	0.212
NCOA6	KMT2C	0.288	0.126
HCFC2	BOD1	0.276	0.236
NCOA6	HCFC1	0.273	0.184
KDM6A	KMT2C	0.266	0.166
ATN1	KMT2C	0.21	0.128
HCFC1	DPY30	0.193	0.164
ATN1	DPY30	0.128	0.222	mutually_exclusive (P61964)
NCOA6	DPY30	0.117	0.366
KMT2C	KMT2D	0.099	0.046
CXXC1	KMT2C	0.095	0.144
KMT2C	SETD1A	0.095	0.144
HCFC2	KMT2C	0.082	0.112
WDR5	KMT2C	0.081	0.042
BOD1L1	KMT2C	0.079	0.096
KMT2C	BOD1	0.079	0.096
SETD1B	KMT2C	0.079	0.104
DPY30	KMT2C	0.078	0.1
KMT2A	KMT2C	0.071	0.07
HCFC1	KMT2C	0.024	0.19

Related Complexes

Genename	Complexes
BOD1L1	huMAP3_00564.1 huMAP3_05226.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
SETD1A	huMAP3_02698.1 huMAP3_05226.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
SETD1B	huMAP3_00564.1 huMAP3_05226.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
KMT2A	huMAP3_00564.1 huMAP3_05226.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
NCOA6	huMAP3_00047.1 huMAP3_05103.1 huMAP3_07585.1 huMAP3_08776.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
CXXC1	huMAP3_00047.1 huMAP3_02698.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
KMT2D	huMAP3_07585.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1 huMAP3_12119.1 huMAP3_12373.1 huMAP3_14057.1 huMAP3_14367.1
KDM6A	huMAP3_00564.1 huMAP3_05226.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
HCFC1	huMAP3_00564.1 huMAP3_02029.1 huMAP3_07065.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09094.1 huMAP3_10106.1 huMAP3_10650.1 huMAP3_11602.1 huMAP3_13421.1
HCFC2	huMAP3_00564.1 huMAP3_05226.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
DPY30	huMAP3_00564.1 huMAP3_05226.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1 huMAP3_13844.1
ASH2L	huMAP3_05226.1 huMAP3_06804.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
ATN1	huMAP3_00047.1 huMAP3_05103.1 huMAP3_07585.1 huMAP3_08776.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
RBBP5	huMAP3_00564.1 huMAP3_05226.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
KMT2C	huMAP3_00564.1 huMAP3_05226.1 huMAP3_06804.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1 huMAP3_12999.1
WDR5	huMAP3_00047.1 huMAP3_05103.1 huMAP3_07585.1 huMAP3_08776.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1
BOD1	huMAP3_00564.1 huMAP3_05226.1 huMAP3_07065.1 huMAP3_08776.1 huMAP3_08895.1 huMAP3_09051.1 huMAP3_09422.1 huMAP3_10027.1 huMAP3_10650.1 huMAP3_11602.1 huMAP3_11792.1 huMAP3_15215.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_09051.1

Complex Portal: CPX-19677