hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09054.1
Complex Portal: CPX-11676
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LAMA4 | Laminin subunit alpha-4 (Laminin-14 subunit alpha) (Laminin-8 subunit alpha) (Laminin-9 subunit alpha) | 5 | UniProt NCBI |
| NID2 | Nidogen-2 (NID-2) (Osteonidogen) | 5 | UniProt NCBI |
| PPIB | Peptidyl-prolyl cis-trans isomerase B (PPIase B) (EC 5.2.1.8) (CYP-S1) (Cyclophilin B) (Rotamase B) (S-cyclophilin) (SCYLP) | 5 | UniProt NCBI |
| PILRA | Paired immunoglobulin-like type 2 receptor alpha (Cell surface receptor FDF03) (Inhibitory receptor PILR-alpha) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-3000157 | 0.00239054881557 | 0.666666666667 | LAMA4 NID2 | Laminin interactions |
| KEGG:03266 | 0.0390296209856 | 0.333333333333 | PILRA | Virion - Herpesvirus |
| CORUM:2374 | 0.0499402709677 | 0.333333333333 | LAMA4 | ITGAV-ITGB3-LAMA4 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| LAMA4 | NID2 | 0.988 | 0.264 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM WMM_only | |
| PILRA | NID2 | 0.976 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PPIB | NID2 | 0.973 | 0.168 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| LAMA4 | PILRA | 0.958 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | ||
| PPIB | LAMA4 | 0.059 | 0.156 | bioplex3_WMM WMM_only | |
| PPIB | PILRA | 0.003 | bioplex3_HEK293 bioplex () bioplex3_HCT116 |
Related Complexes