hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09084.1
Complex Portal: CPX-14308
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NAB1 | NGFI-A-binding protein 1 (EGR-1-binding protein 1) (Transcriptional regulatory protein p54) | 5 | UniProt NCBI |
| EGR1 | Early growth response protein 1 (EGR-1) (AT225) (Nerve growth factor-induced protein A) (NGFI-A) (Transcription factor ETR103) (Transcription factor Zif268) (Zinc finger protein 225) (Zinc finger protein Krox-24) | 5 | UniProt NCBI |
| PRICKLE4 | Prickle-like protein 4 (Overexpressed breast tumor protein) | 4 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-9031628 | 0.0033773260227 | 0.666666666667 | EGR1 NAB1 | NGF-stimulated transcription |
| REAC:R-HSA-198725 | 0.00973406489476 | 0.666666666667 | EGR1 NAB1 | Nuclear Events (kinase and transcription factor activation) |
| REAC:R-HSA-187037 | 0.0316091445651 | 0.666666666667 | EGR1 NAB1 | Signaling by NTRK1 (TRKA) |
| WP:WP3299 | 0.0413734636003 | 0.333333333333 | EGR1 | let 7 inhibition of ES cell reprogramming |
| REAC:R-HSA-166520 | 0.0436932800731 | 0.666666666667 | EGR1 NAB1 | Signaling by NTRKs |
| CORUM:5375 | 0.0499402709677 | 0.333333333333 | EGR1 | EGR-EP300 complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| NAB1 | PRICKLE4 | 0.99 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| EGR1 | NAB1 | 0.985 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes