hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09091.1
Complex Portal: CPX-24279
Confidence: Moderate High  
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MECP2 | Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2) | 5 | UniProt   NCBI |
| NMNAT1 | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 (NMN/NaMN adenylyltransferase 1) (EC 2.7.7.1) (EC 2.7.7.18) (Nicotinamide-nucleotide adenylyltransferase 1) (NMN adenylyltransferase 1) (Nicotinate-nucleotide adenylyltransferase 1) (NaMN adenylyltransferase 1) | 5 | UniProt   NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
|   HP:5200017 | 0.0036943429081 | 1.0 | MECP2 NMNAT1 | Abnormal movements of face and head |
|   WP:WP5420 | 0.0144418640295 | 1.0 | MECP2 NMNAT1 | ADHD and autism ASD linked metabolic pathways and SNP |
|   WP:WP2485 | 0.0435328773163 | 0.5 | NMNAT1 | NAD biosynthesis II from tryptophan |
|   WP:WP3585 | 0.0435328773163 | 0.5 | MECP2 | Cytosine methylation |
|   HP:0006919 | 0.0499436884913 | 0.5 | MECP2 | Abnormal aggressive, impulsive or violent behavior |
|   HP:0032123 | 0.0499436884913 | 0.5 | NMNAT1 | Ultra-low vision |
|   HP:0032286 | 0.0499436884913 | 0.5 | NMNAT1 | Ultra-low vision with retained light perception |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
|  MECP2 |  NMNAT1 | 0.964 | 0.026           |          | hein_WMM     bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
Related Complexes