hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_09091.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| MECP2 | Methyl-CpG-binding protein 2 (MeCp-2 protein) (MeCp2) | 5 | UniProt NCBI |
| NMNAT1 | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 (NMN/NaMN adenylyltransferase 1) (EC 2.7.7.1) (EC 2.7.7.18) (Nicotinamide-nucleotide adenylyltransferase 1) (NMN adenylyltransferase 1) (Nicotinate-nucleotide adenylyltransferase 1) (NaMN adenylyltransferase 1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:5200017 | 0.0036943429081 | 1.0 | NMNAT1 MECP2 | Abnormal movements of face and head |
| WP:WP5420 | 0.0144418640295 | 1.0 | NMNAT1 MECP2 | ADHD and autism ASD linked metabolic pathways and SNP |
| WP:WP2485 | 0.0435328773163 | 0.5 | NMNAT1 | NAD biosynthesis II from tryptophan |
| WP:WP3585 | 0.0435328773163 | 0.5 | MECP2 | Cytosine methylation |
| HP:0006919 | 0.0499436884913 | 0.5 | MECP2 | Abnormal aggressive, impulsive or violent behavior |
| HP:0032123 | 0.0499436884913 | 0.5 | NMNAT1 | Ultra-low vision |
| HP:0032286 | 0.0499436884913 | 0.5 | NMNAT1 | Ultra-low vision with retained light perception |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MECP2 | NMNAT1 | 0.964 | 0.026 | hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes