hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09093.1
Complex Portal: CPX-12339
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| KCNA6 | Potassium voltage-gated channel subfamily A member 6 (Voltage-gated potassium channel HBK2) (Voltage-gated potassium channel subunit Kv1.6) | 5 | UniProt NCBI |
| KCNA3 | Potassium voltage-gated channel subfamily A member 3 (HGK5) (HLK3) (HPCN3) (Voltage-gated K(+) channel HuKIII) (Voltage-gated potassium channel subunit Kv1.3) | 5 | UniProt NCBI |
| VAT1 | Synaptic vesicle membrane protein VAT-1 homolog (EC 1.-.-.-) | 5 | UniProt NCBI |
| KCNA5 | Potassium voltage-gated channel subfamily A member 5 (HPCN1) (Voltage-gated potassium channel HK2) (Voltage-gated potassium channel subunit Kv1.5) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1296072 | 0.00221357222266 | 0.666666666667 | KCNA3 KCNA5 | Voltage gated Potassium channels |
| REAC:R-HSA-1296071 | 0.0145828870271 | 0.666666666667 | KCNA3 KCNA5 | Potassium Channels |
| WP:WP5420 | 0.0379798583444 | 0.666666666667 | KCNA3 KCNA5 | ADHD and autism ASD linked metabolic pathways and SNP |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| KCNA6 | KCNA3 | 0.985 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| KCNA6 | VAT1 | 0.976 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM bioplex3_HCT116 | ||
| KCNA5 | KCNA3 | 0.975 |
structurally_consistent (dimer)
|
bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| VAT1 | KCNA3 | 0.112 | bioplex_WMM bioplex3_WMM WMM_only |
Related Complexes