hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09098.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| LETM2 | LETM1 domain-containing protein LETM2, mitochondrial (LETM1 and EF-hand domain-containing protein 2) (Leucine zipper-EF-hand-containing transmembrane protein 1-like) | 3 | UniProt NCBI |
| DYNC2I1 | Cytoplasmic dynein 2 intermediate chain 1 (Dynein 2 intermediate chain 1) (WD repeat-containing protein 60) | 5 | UniProt NCBI |
| DYNLT4 | Dynein light chain Tctex-type 4 (Protein N22.1) (Tctex-2-beta) (Tctex1 domain-containing protein 4) | 5 | UniProt NCBI |
| ABHD17B | Alpha/beta hydrolase domain-containing protein 17B (Abhydrolase domain-containing protein 17B) (EC 3.1.2.22) | 5 | UniProt NCBI |
| DYNLT2B | Dynein light chain Tctex-type protein 2B (Tctex1 domain-containing protein 2) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HP:0010454 | 0.000641107533884 | 0.4 | DYNC2I1 DYNLT2B | Acetabular spurs |
| CORUM:6236 | 0.000899678549321 | 0.4 | DYNC2I1 DYNLT2B | Dynein-2 complex, cytoplasmic |
| GO:0005868 | 0.00127603542925 | 0.6 | DYNC2I1 DYNLT2B DYNLT4 | cytoplasmic dynein complex |
| WP:WP4532 | 0.00205749802636 | 0.4 | DYNC2I1 DYNLT2B | Intraflagellar transport proteins binding to dynein |
| GO:0030286 | 0.00522817157061 | 0.6 | DYNC2I1 DYNLT2B DYNLT4 | dynein complex |
| HP:0000895 | 0.00582689447108 | 0.4 | DYNC2I1 DYNLT2B | Lateral clavicle hook |
| WP:WP4906 | 0.00931707261303 | 0.4 | DYNC2I1 DYNLT2B | 3q29 copy number variation syndrome |
| GO:0031021 | 0.0140440992017 | 0.4 | DYNC2I1 DYNLT2B | interphase microtubule organizing center |
| WP:WP5234 | 0.0165943234371 | 0.4 | DYNC2I1 DYNLT2B | Bardet Biedl syndrome |
| REAC:R-HSA-5620924 | 0.0192520251047 | 0.4 | DYNC2I1 DYNLT2B | Intraflagellar transport |
| WP:WP4536 | 0.0275912236597 | 0.4 | DYNC2I1 DYNLT2B | Genes related to primary cilium development based on CRISPR |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| DYNC2I1 | DYNLT2B | 1.0 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 gupta_WMM boldt_WMM | |
| DYNLT2B | DYNLT4 | 0.999 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| DYNLT2B | ABHD17B | 0.996 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM boldt bioplex3_HCT116 boldt_WMM | |
| DYNLT4 | ABHD17B | 0.993 | bioplex3_HEK293 bioplex3_WMM bioplex3_HCT116 WMM_only | |
| LETM2 | DYNLT2B | 0.982 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| DYNC2I1 | DYNLT4 | 0.717 | bioplex3_HEK293 bioplex3_WMM WMM_only | |
| DYNC2I1 | ABHD17B | 0.54 | 0.062 | bioplex_WMM bioplex3_WMM boldt boldt_WMM WMM_only |
Related Complexes