hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09104.1
Complex Portal: CPX-23433
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| DIO3 | Thyroxine 5-deiodinase (EC 1.21.99.3) (5DIII) (DIOIII) (Type 3 DI) (Type III iodothyronine deiodinase) | 5 | UniProt NCBI |
| HERC3 | Probable E3 ubiquitin-protein ligase HERC3 (EC 2.3.2.26) (HECT domain and RCC1-like domain-containing protein 3) (HECT-type E3 ubiquitin transferase HERC3) | 4 | UniProt NCBI |
| BLTP3B | Bridge-like lipid transfer protein family member 3B (Syntaxin-6 Habc-interacting protein of 164 kDa) (UHRF1-binding protein 1-like) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-350864 | 0.0498224659464 | 0.333333333333 | DIO3 | Regulation of thyroid hormone activity |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| DIO3 | BLTP3B | 0.996 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| DIO3 | HERC3 | 0.99 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| HERC3 | BLTP3B | 0.56 | bioplex3_WMM WMM_only |
Related Complexes
| Genename | Complexes |
|---|---|
| DIO3 | huMAP3_01032.1 huMAP3_09104.1 huMAP3_14009.1 |
| HERC3 | huMAP3_01032.1 huMAP3_02853.1 huMAP3_09104.1 huMAP3_09769.1 huMAP3_11434.1 |
| BLTP3B | huMAP3_07347.1 huMAP3_08536.1 huMAP3_08990.1 huMAP3_09104.1 huMAP3_09634.1 huMAP3_12566.1 |