hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_09125.1

Complex Portal: CPX-12680

Confidence: Moderate High

Genename	Protein Name	Uniprot Annotation Score	Links
CASP14	Caspase-14 (CASP-14) (EC 3.4.22.-) [Cleaved into: Caspase-14 subunit p17, mature form; Caspase-14 subunit p10, mature form; Caspase-14 subunit p20, intermediate form; Caspase-14 subunit p8, intermediate form]	5	UniProt NCBI
GGCT	Gamma-glutamylcyclotransferase (EC 4.3.2.9) (Cytochrome c-releasing factor 21)	5	UniProt NCBI
ARG1	Arginase-1 (EC 3.5.3.1) (Liver-type arginase) (Type I arginase)	5	UniProt NCBI
TREX2	Three prime repair exonuclease 2 (EC 3.1.11.2) (3'-5' exonuclease TREX2)	5	UniProt NCBI
KPRP	Keratinocyte proline-rich protein (hKPRP)	5	UniProt NCBI
HAL	Histidine ammonia-lyase (Histidase) (EC 4.3.1.3)	4	UniProt NCBI
S100A8	Protein S100-A8 (Calgranulin-A) (Calprotectin L1L subunit) (Cystic fibrosis antigen) (CFAG) (Leukocyte L1 complex light chain) (Migration inhibitory factor-related protein 8) (MRP-8) (p8) (S100 calcium-binding protein A8) (Urinary stone protein band A)	5	UniProt NCBI
GM2A	Ganglioside GM2 activator (Cerebroside sulfate activator protein) (GM2-AP) (Sphingolipid activator protein 3) (SAP-3) [Cleaved into: Ganglioside GM2 activator isoform short]	5	UniProt NCBI
EVPL	Envoplakin (210 kDa cornified envelope precursor protein) (210 kDa paraneoplastic pemphigus antigen) (p210)	5	UniProt NCBI
SBSN	Suprabasin	3	UniProt NCBI
TGM1	Protein-glutamine gamma-glutamyltransferase K (EC 2.3.2.13) (Epidermal TGase) (Transglutaminase K) (TG(K)) (TGK) (TGase K) (Transglutaminase-1) (TGase-1)	5	UniProt NCBI
AZGP1	Zinc-alpha-2-glycoprotein (Zn-alpha-2-GP) (Zn-alpha-2-glycoprotein)	5	UniProt NCBI
ASAH1	Acid ceramidase (AC) (ACDase) (Acid CDase) (EC 3.5.1.23) (Acylsphingosine deacylase) (N-acylethanolamine hydrolase ASAH1) (EC 3.5.1.-) (N-acylsphingosine amidohydrolase) (Putative 32 kDa heart protein) (PHP32) [Cleaved into: Acid ceramidase subunit alpha; Acid ceramidase subunit beta]	5	UniProt NCBI
TYMP	Thymidine phosphorylase (TP) (EC 2.4.2.4) (Gliostatin) (Platelet-derived endothelial cell growth factor) (PD-ECGF) (TdRPase)	5	UniProt NCBI
S100A9	Protein S100-A9 (Calgranulin-B) (Calprotectin L1H subunit) (Leukocyte L1 complex heavy chain) (Migration inhibitory factor-related protein 14) (MRP-14) (p14) (S100 calcium-binding protein A9)	5	UniProt NCBI
S100A7A	Protein S100-A7A (S100 calcium-binding protein A15) (S100 calcium-binding protein A7-like 1) (S100 calcium-binding protein A7A)	5	UniProt NCBI
TGM3	Protein-glutamine gamma-glutamyltransferase E (EC 2.3.2.13) (Transglutaminase E) (TG(E)) (TGE) (TGase E) (Transglutaminase-3) (TGase-3) [Cleaved into: Protein-glutamine gamma-glutamyltransferase E 50 kDa catalytic chain; Protein-glutamine gamma-glutamyltransferase E 27 kDa non-catalytic chain]	5	UniProt NCBI
NCCRP1	F-box only protein 50 (NCC receptor protein 1 homolog) (NCCRP-1) (Non-specific cytotoxic cell receptor protein 1 homolog)	4	UniProt NCBI
PKP1	Plakophilin-1 (Band 6 protein) (B6P)	5	UniProt NCBI
ECM1	Extracellular matrix protein 1 (Secretory component p85)	5	UniProt NCBI
FLG2	Filaggrin-2 (FLG-2) (Intermediate filament-associated and psoriasis-susceptibility protein) (Ifapsoriasin)	5	UniProt NCBI
GSDMA	Gasdermin-A (Gasdermin-1) [Cleaved into: Gasdermin-A, N-terminal (GSDMA-NT); Gasdermin-A, C-terminal (GSDMA-CT)]	5	UniProt NCBI
FLG	Filaggrin	5	UniProt NCBI
KIR3DS1	Killer cell immunoglobulin-like receptor 3DS1 (Natural killer-associated transcript 10) (NKAT-10)	5	UniProt NCBI
DSP	Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen)	5	UniProt NCBI
S100A7	Protein S100-A7 (Psoriasin) (S100 calcium-binding protein A7)	5	UniProt NCBI
KLK7	Kallikrein-7 (hK7) (EC 3.4.21.117) (Serine protease 6) (Stratum corneum chymotryptic enzyme) (hSCCE)	5	UniProt NCBI
DSG1	Desmoglein-1 (Cadherin family member 4) (Desmosomal glycoprotein 1) (DG1) (DGI) (Pemphigus foliaceus antigen)	5	UniProt NCBI
FCGBP	IgGFc-binding protein (Fcgamma-binding protein antigen) (FcgammaBP)	5	UniProt NCBI
DSC1	Desmocollin-1 (Cadherin family member 1) (Desmosomal glycoprotein 2/3) (DG2/DG3)	5	UniProt NCBI
S100A14	Protein S100-A14 (S100 calcium-binding protein A14) (S114)	5	UniProt NCBI
ACP3	Prostatic acid phosphatase (PAP) (EC 3.1.3.2) (5'-nucleotidase) (5'-NT) (EC 3.1.3.5) (Acid phosphatase 3) (Ecto-5'-nucleotidase) (Protein tyrosine phosphatase ACP3) (EC 3.1.3.48) (Thiamine monophosphatase) (TMPase) [Cleaved into: PAPf39]	5	UniProt NCBI
CPA4	Carboxypeptidase A4 (EC 3.4.17.-) (Carboxypeptidase A3)	5	UniProt NCBI
HRNR	Hornerin	5	UniProt NCBI
ZIC1	Zinc finger protein ZIC 1 (Zinc finger protein 201) (Zinc finger protein of the cerebellum 1)	5	UniProt NCBI
CTSV	Cathepsin L2 (EC 3.4.22.43) (Cathepsin U) (Cathepsin V)	5	UniProt NCBI
SDR9C7	Short-chain dehydrogenase/reductase family 9C member 7 (EC 1.1.1.-) (Orphan short-chain dehydrogenase/reductase) (SDR-O) (RDH-S)	4	UniProt NCBI
SERPINB12	Serpin B12	5	UniProt NCBI
CALML3	Calmodulin-like protein 3 (CaM-like protein) (CLP) (Calmodulin-related protein NB-1)	4	UniProt NCBI
PPL	Periplakin (190 kDa paraneoplastic pemphigus antigen) (195 kDa cornified envelope precursor protein)	5	UniProt NCBI
JUP	Junction plakoglobin (Catenin gamma) (Desmoplakin III) (Desmoplakin-3)	5	UniProt NCBI
POF1B	Protein POF1B (Premature ovarian failure protein 1B)	5	UniProt NCBI
S100A16	Protein S100-A16 (Aging-associated gene 13 protein) (Protein S100-F) (S100 calcium-binding protein A16)	5	UniProt NCBI
SERPINB3	Serpin B3 (Protein T4-A) (Squamous cell carcinoma antigen 1) (SCCA-1)	5	UniProt NCBI
S100A11	Protein S100-A11 (Calgizzarin) (Metastatic lymph node gene 70 protein) (MLN 70) (Protein S100-C) (S100 calcium-binding protein A11) [Cleaved into: Protein S100-A11, N-terminally processed]	5	UniProt NCBI
CALML5	Calmodulin-like protein 5 (Calmodulin-like skin protein)	5	UniProt NCBI
LCN2	Neutrophil gelatinase-associated lipocalin (NGAL) (25 kDa alpha-2-microglobulin-related subunit of MMP-9) (Lipocalin-2) (Oncogene 24p3) (Siderocalin) (p25)	5	UniProt NCBI
CSTA	Cystatin-A (Cystatin-AS) (Stefin-A) [Cleaved into: Cystatin-A, N-terminally processed]	5	UniProt NCBI
CDSN	Corneodesmosin (S protein)	5	UniProt NCBI
ALOX12B	Arachidonate 12-lipoxygenase, 12R-type (12R-LOX) (12R-lipoxygenase) (EC 1.13.11.-) (Epidermis-type lipoxygenase 12)	5	UniProt NCBI
SERPINB5	Serpin B5 (Maspin) (Peptidase inhibitor 5) (PI-5)	5	UniProt NCBI
PKP3	Plakophilin-3	5	UniProt NCBI
SERPINA12	Serpin A12 (OL-64) (Visceral adipose tissue-derived serine protease inhibitor) (Vaspin) (Visceral adipose-specific serpin)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
HPA:0471401	1.22559704842e-20	0.372093023256	DSC1 S100A9 SERPINB5 ECM1 HAL CSTA S100A14 CASP14 DSG1 KLK7 TGM1 S100A16 SBSN S100A7 S100A8 ALOX12B	skin 2; cells in corneal layer[>=Low]
HPA:0461402	3.56625019714e-20	0.302325581395	ECM1 SERPINB5 DSC1 CSTA CASP14 ALOX12B DSG1 KLK7 TGM1 S100A14 S100A7 S100A16 KPRP	skin 1; cells in corneal layer[>=Medium]
HPA:0471402	5.34277342481e-20	0.325581395349	DSC1 S100A9 SERPINB5 ECM1 CSTA CASP14 DSG1 KLK7 TGM1 S100A16 S100A14 S100A7 S100A8 ALOX12B	skin 2; cells in corneal layer[>=Medium]
HPA:0461401	9.53926752514e-20	0.325581395349	ECM1 SERPINB5 DSC1 HAL CSTA CASP14 ALOX12B DSG1 KLK7 TGM1 S100A14 S100A7 S100A16 KPRP	skin 1; cells in corneal layer[>=Low]
HPA:0470181	4.8691717088e-15	0.488372093023	CALML5 S100A9 SERPINB5 EVPL PKP3 DSC1 PPL HAL CSTA S100A14 CASP14 PKP1 KLK7 S100A16 KPRP CALML3 SBSN S100A7 DSG1 S100A8 S100A11	skin 2; cells in granular layer[>=Low]
HPA:0470182	1.8270349769e-14	0.441860465116	CALML5 S100A9 SERPINB5 EVPL PKP3 DSC1 HAL CSTA S100A14 CASP14 PKP1 KLK7 S100A16 KPRP CALML3 SBSN S100A7 S100A8 S100A11	skin 2; cells in granular layer[>=Medium]
GO:0001533	1.36857011567e-13	0.232558139535	EVPL HRNR PKP3 DSG1 PKP1 DSC1 FLG2 CSTA PPL TGM1	cornified envelope
HPA:0460181	1.62337785885e-12	0.441860465116	CALML5 ECM1 SERPINB5 EVPL PKP3 DSC1 HAL CSTA S100A14 CASP14 PKP1 KLK7 KPRP S100A16 SBSN S100A7 DSG1 PPL S100A11	skin 1; cells in granular layer[>=Low]
HPA:0460182	7.2828964564e-12	0.395348837209	CALML5 SERPINB5 EVPL PKP3 DSC1 HAL CSTA S100A14 CASP14 PKP1 KLK7 KPRP SBSN S100A7 DSG1 S100A16 S100A11	skin 1; cells in granular layer[>=Medium]
HPA:0471412	1.34640941738e-11	0.418604651163	CALML5 S100A9 EVPL PKP3 CALML3 HAL CSTA S100A14 CASP14 PKP1 DSC1 S100A11 S100A16 SBSN S100A7 DSG1 S100A8 SERPINB5	skin 2; cells in spinous layer[>=Medium]
HPA:0470183	1.55379722024e-11	0.302325581395	S100A9 CALML5 SERPINB5 HAL CSTA S100A14 CASP14 S100A16 DSC1 KPRP SBSN S100A7 S100A8	skin 2; cells in granular layer[High]
HPA:0471411	6.8236895942e-11	0.441860465116	CALML5 S100A9 EVPL PKP3 CALML3 PPL HAL CSTA S100A14 CASP14 PKP1 DSC1 S100A11 S100A16 SBSN S100A7 DSG1 S100A8 SERPINB5	skin 2; cells in spinous layer[>=Low]
REAC:R-HSA-6809371	8.74188932901e-11	0.209302325581	EVPL PKP3 DSG1 PKP1 DSC1 CASP14 TGM1 CSTA PPL	Formation of the cornified envelope
REAC:R-HSA-6805567	1.1538093656e-10	0.209302325581	EVPL PKP3 DSG1 PKP1 DSC1 CASP14 TGM1 CSTA PPL	Keratinization
REAC:R-HSA-6799990	3.55431037209e-10	0.116279069767	LCN2 S100A9 S100A7 S100A8 S100A7A	Metal sequestration by antimicrobial proteins
HPA:0461403	4.6669358034e-10	0.162790697674	CASP14 DSG1 DSC1 ALOX12B CSTA S100A7 S100A16	skin 1; cells in corneal layer[High]
GO:0008544	1.50750097363e-09	0.279069767442	TGM3 EVPL ASAH1 HRNR CALML5 CASP14 ALOX12B KLK7 FLG2 CSTA S100A7 TGM1	epidermis development
REAC:R-HSA-6798695	3.52624005228e-09	0.325581395349	S100A9 ARG1 HRNR CALML5 PKP1 DSG1 DSC1 S100A11 FLG2 SERPINB12 LCN2 S100A7 S100A8 ASAH1	Neutrophil degranulation
GO:0005576	3.52813162392e-09	0.720930232558	GGCT CTSV DSC1 S100A11 S100A7 S100A14 S100A8 TGM3 KLK7 S100A7A CSTA KPRP S100A16 HRNR CALML5 LCN2 FLG2 ECM1 ARG1 CALML3 SERPINA12 ASAH1 SERPINB12 NCCRP1 S100A9 EVPL CPA4 TGM1 SBSN PPL SERPINB5	extracellular region
HPA:0460183	9.87850171224e-09	0.255813953488	EVPL SERPINB5 HAL CSTA S100A14 CASP14 DSC1 CALML5 SBSN S100A7 S100A16	skin 1; cells in granular layer[High]
HPA:0461411	1.85625097198e-08	0.372093023256	S100A9 EVPL PKP3 SERPINB5 HAL CSTA S100A14 CASP14 PKP1 DSC1 S100A11 S100A16 SBSN S100A7 DSG1 PPL	skin 1; cells in spinous layer[>=Low]
GO:0005615	2.61938174076e-08	0.674418604651	GGCT CTSV DSC1 S100A11 S100A7 S100A14 S100A8 TGM3 KLK7 S100A7A CSTA S100A16 HRNR LCN2 KPRP ECM1 ARG1 CALML3 SERPINA12 ASAH1 SERPINB12 NCCRP1 S100A9 EVPL CPA4 TGM1 SBSN PPL SERPINB5	extracellular space
HPA:0461412	7.77918909361e-08	0.325581395349	S100A9 EVPL PKP3 SERPINB5 HAL S100A14 CASP14 PKP1 DSC1 S100A11 SBSN S100A7 DSG1 S100A16	skin 1; cells in spinous layer[>=Medium]
HPA:0471403	9.93497435594e-08	0.139534883721	CASP14 DSG1 DSC1 ALOX12B CSTA S100A7	skin 2; cells in corneal layer[High]
HP:0011124	1.07576053234e-07	0.186046511628	ECM1 PKP1 ALOX12B DSG1 CASP14 FLG2 CSTA TGM1	Abnormal epidermal morphology
GO:0043588	1.39590959433e-07	0.232558139535	TGM3 EVPL ASAH1 CASP14 ALOX12B HRNR FLG2 CSTA S100A7 TGM1	skin development
HPA:0471413	2.63279117436e-07	0.232558139535	S100A9 SERPINB5 CALML5 DSG1 CASP14 DSC1 S100A16 S100A14 S100A7 S100A8	skin 2; cells in spinous layer[High]
REAC:R-HSA-168249	5.80055554069e-07	0.372093023256	CALML5 S100A9 CTSV ARG1 HRNR S100A7A PKP1 DSG1 DSC1 S100A11 ASAH1 SERPINB12 LCN2 S100A7 S100A8 FLG2	Innate Immune System
HPA:0461451	6.6822172483e-07	0.255813953488	S100A9 DSC1 SBSN PKP1 PPL KLK7 TGM1 S100A16 S100A14 S100A7 CALML3	skin 1; hair follicles[>=Low]
GO:0030141	8.43966916148e-07	0.372093023256	DSC1 S100A9 ARG1 ECM1 CALML5 HRNR PKP1 DSG1 KLK7 S100A11 ASAH1 SERPINB12 LCN2 S100A7 S100A8 FLG2	secretory granule
GO:0005509	1.16560540996e-06	0.279069767442	S100A9 CALML5 TGM3 S100A7A DSG1 S100A16 DSC1 S100A11 CALML3 S100A14 S100A7 S100A8	calcium ion binding
HPA:0471461	2.89797904508e-06	0.325581395349	S100A9 PKP3 CALML3 HAL S100A14 CASP14 PKP1 SERPINB5 FCGBP SBSN S100A7 DSG1 S100A8 S100A11	skin 2; langerhans cells[>=Low]
HPA:0471462	3.33598307459e-06	0.302325581395	S100A9 PKP3 CALML3 HAL S100A14 CASP14 PKP1 SERPINB5 S100A11 SBSN S100A7 DSG1 S100A8	skin 2; langerhans cells[>=Medium]
HPA:0471391	4.50058561174e-06	0.348837209302	S100A9 EVPL PKP3 CALML3 HAL PKP1 CASP14 SERPINB5 FCGBP S100A16 CALML5 S100A14 DSG1 S100A8 S100A11	skin 2; cells in basal layer[>=Low]
GO:0099503	6.7142025035e-06	0.372093023256	DSC1 S100A9 ARG1 ECM1 CALML5 HRNR PKP1 DSG1 KLK7 S100A11 ASAH1 SERPINB12 LCN2 S100A7 S100A8 FLG2	secretory vesicle
HPA:0461391	1.2762384662e-05	0.325581395349	S100A9 EVPL PKP3 CALML3 HAL PKP1 CASP14 SERPINB5 FCGBP S100A14 S100A7 DSG1 S100A16 S100A11	skin 1; cells in basal layer[>=Low]
GO:0048306	1.35502321329e-05	0.162790697674	S100A9 S100A7A S100A16 S100A11 S100A14 S100A7 S100A8	calcium-dependent protein binding
HP:0000972	3.12059213833e-05	0.162790697674	SDR9C7 SERPINA12 DSG1 PKP1 TGM1 CSTA ALOX12B	Palmoplantar hyperkeratosis
HP:0010765	3.33181513412e-05	0.162790697674	SDR9C7 SERPINA12 DSG1 PKP1 TGM1 CSTA ALOX12B	Palmar hyperkeratosis
HP:0007556	3.55503076787e-05	0.162790697674	SDR9C7 SERPINA12 DSG1 PKP1 TGM1 CSTA ALOX12B	Plantar hyperkeratosis
GO:0031982	8.38632950711e-05	0.627906976744	GGCT DSC1 S100A11 S100A7 S100A14 S100A8 TGM3 SBSN KPRP S100A16 HRNR LCN2 FLG2 ECM1 ARG1 CALML3 PKP1 DSG1 ASAH1 SERPINB12 NCCRP1 S100A9 EVPL KLK7 TGM1 CALML5 PPL	vesicle
HP:0000962	0.00013216371412	0.186046511628	SDR9C7 SERPINA12 ECM1 DSG1 PKP1 TGM1 CSTA ALOX12B	Hyperkeratosis
GO:0030216	0.000154913817294	0.162790697674	TGM3 EVPL CASP14 TGM1 CSTA S100A7 ASAH1	keratinocyte differentiation
HP:0040189	0.000166873503896	0.116279069767	CSTA FLG2 PKP1 CASP14 TGM1	Scaling skin
HPA:0230331	0.0001737457388	0.0697674418605	GSDMA CASP14 DSC1	hair; cells in internal root sheath[>=Low]
HPA:0230332	0.0001737457388	0.0697674418605	GSDMA CASP14 DSC1	hair; cells in internal root sheath[>=Medium]
KEGG:04657	0.000191236785722	0.116279069767	LCN2 S100A9 S100A7 S100A8 S100A7A	IL-17 signaling pathway
HP:0100872	0.00020340643488	0.162790697674	SDR9C7 SERPINA12 DSG1 PKP1 TGM1 CSTA ALOX12B	Abnormality of the plantar skin of foot
GO:0046872	0.000207118203915	0.348837209302	CALML5 S100A9 ARG1 TGM3 S100A7A DSG1 S100A16 DSC1 S100A11 CALML3 S100A14 LCN2 S100A7 S100A8 TREX2	metal ion binding
REAC:R-HSA-6803157	0.000222056667971	0.116279069767	LCN2 S100A9 S100A7 S100A8 S100A7A	Antimicrobial peptides
HPA:0461453	0.000233696387098	0.139534883721	CALML3 SBSN DSC1 S100A7 S100A14 S100A16	skin 1; hair follicles[High]
HP:0000982	0.000395060479127	0.139534883721	SDR9C7 DSG1 PKP1 TGM1 CSTA ALOX12B	Palmoplantar keratoderma
HP:0011368	0.000409559285813	0.209302325581	ECM1 SERPINA12 SDR9C7 DSG1 ALOX12B PKP1 FLG2 CSTA TGM1	Epidermal thickening
GO:0043169	0.000610775994762	0.348837209302	CALML5 S100A9 ARG1 TGM3 S100A7A DSG1 S100A16 DSC1 S100A11 CALML3 S100A14 LCN2 S100A7 S100A8 TREX2	cation binding
REAC:R-HSA-168256	0.000798483392825	0.395348837209	CALML5 S100A9 CTSV ARG1 HRNR PPL S100A7A PKP1 DSG1 DSC1 S100A11 ASAH1 SERPINB12 LCN2 S100A7 S100A8 FLG2	Immune System
HPA:0471392	0.00101290230374	0.255813953488	S100A9 EVPL CALML3 HAL DSG1 PKP1 SERPINB5 S100A11 PKP3 S100A14 S100A16	skin 2; cells in basal layer[>=Medium]
HP:0001072	0.0011291844974	0.209302325581	ECM1 SERPINA12 SDR9C7 DSG1 ALOX12B PKP1 FLG2 CSTA TGM1	Thickened skin
HPA:0470000	0.00121361668551	0.767441860465	ECM1 GGCT CASP14 DSC1 S100A11 CSTA S100A14 S100A8 TGM3 SBSN S100A16 SERPINB5 CALML5 LCN2 KPRP GSDMA FCGBP PKP3 TGM1 DSG1 PKP1 ASAH1 S100A7 NCCRP1 S100A9 EVPL HAL PPL KLK7 FLG2 S100A7A CALML3 ALOX12B	skin 2
GO:0009913	0.00127981107643	0.162790697674	TGM3 EVPL CASP14 TGM1 CSTA S100A7 ASAH1	epidermal cell differentiation
HPA:0461392	0.0016578226264	0.232558139535	S100A9 EVPL HAL DSG1 PKP1 SERPINB5 S100A11 PKP3 S100A14 S100A16	skin 1; cells in basal layer[>=Medium]
HPA:0471463	0.0017123072064	0.162790697674	S100A9 DSG1 CASP14 SERPINB5 S100A14 S100A7 S100A8	skin 2; langerhans cells[High]
HPA:0230000	0.00178116083352	0.0697674418605	GSDMA CASP14 DSC1	hair
CORUM:6826	0.00179908617121	0.046511627907	S100A9 S100A8	Calprotectin heterotetramer
HPA:0460000	0.00236782864048	0.767441860465	ECM1 GGCT CASP14 DSC1 S100A11 CSTA S100A14 TGM3 SBSN KPRP S100A16 SERPINB5 CALML5 TGM1 GSDMA ARG1 FCGBP PKP3 DSG1 PKP1 ASAH1 S100A7 NCCRP1 S100A9 EVPL HAL PPL KLK7 POF1B FLG2 S100A7A CALML3 ALOX12B	skin 1
HPA:0461452	0.00323485415758	0.162790697674	CALML3 SBSN PKP1 DSC1 S100A7 S100A14 S100A16	skin 1; hair follicles[>=Medium]
HPA:0461481	0.00408075015573	0.139534883721	CALML3 S100A9 SBSN PKP1 S100A7 S100A16	skin 1; sebaceous glands[>=Low]
HPA:0461461	0.00474946245473	0.232558139535	PKP3 HAL DSG1 CASP14 SERPINB5 FCGBP S100A14 S100A7 PKP1 S100A11	skin 1; langerhans cells[>=Low]
HPA:0461413	0.0048561923824	0.139534883721	DSC1 DSG1 SERPINB5 S100A14 S100A7 S100A16	skin 1; cells in spinous layer[High]
WP:WP2840	0.00514663759447	0.093023255814	GSDMA DSG1 CASP14 KLK7	Hair follicle development cytodifferentiation part 3 of 3
CORUM:6827	0.00538716304618	0.046511627907	S100A9 S100A8	iNOS-S100A8/A9 complex
HPA:0461462	0.005685637554	0.209302325581	PKP3 HAL DSG1 CASP14 SERPINB5 S100A11 S100A14 S100A7 PKP1	skin 1; langerhans cells[>=Medium]
HP:0025092	0.0112420124994	0.093023255814	CSTA TGM1 ALOX12B DSG1	Epidermal acanthosis
GO:0060429	0.0121807569231	0.255813953488	TGM3 EVPL ASAH1 CASP14 ALOX12B POF1B HRNR FLG2 CSTA S100A7 TGM1	epithelium development
GO:0018149	0.0121892208681	0.093023255814	TGM3 CSTA EVPL TGM1	peptide cross-linking
GO:0070062	0.0132873284238	0.441860465116	S100A9 EVPL ASAH1 TGM3 PPL GGCT HRNR NCCRP1 DSC1 S100A16 S100A11 TGM1 CALML3 SBSN LCN2 S100A14 S100A8 ECM1 KPRP	extracellular exosome
GO:1903561	0.0153854314821	0.441860465116	S100A9 EVPL ASAH1 TGM3 PPL GGCT HRNR NCCRP1 DSC1 S100A16 S100A11 TGM1 CALML3 SBSN LCN2 S100A14 S100A8 ECM1 KPRP	extracellular vesicle
GO:0043230	0.0155178858184	0.441860465116	S100A9 EVPL ASAH1 TGM3 PPL GGCT HRNR NCCRP1 DSC1 S100A16 S100A11 TGM1 CALML3 SBSN LCN2 S100A14 S100A8 ECM1 KPRP	extracellular organelle
GO:0065010	0.0155178858184	0.441860465116	S100A9 EVPL ASAH1 TGM3 PPL GGCT HRNR NCCRP1 DSC1 S100A16 S100A11 TGM1 CALML3 SBSN LCN2 S100A14 S100A8 ECM1 KPRP	extracellular membrane-bounded organelle
HPA:0471441	0.0157376953241	0.255813953488	S100A9 CALML3 HAL CASP14 PPL S100A11 FCGBP CALML5 CSTA S100A8 KPRP	skin 2; fibrohistiocytic cells[>=Low]
GO:0009888	0.0166653069762	0.325581395349	TGM3 EVPL ECM1 CSTA CALML5 HRNR CASP14 ALOX12B POF1B KLK7 TGM1 FLG2 S100A7 ASAH1	tissue development
HPA:0461483	0.0175404102852	0.093023255814	SBSN S100A7 CALML3 S100A9	skin 1; sebaceous glands[High]
HPA:0230333	0.0177391427332	0.046511627907	GSDMA DSC1	hair; cells in internal root sheath[High]
HPA:0450611	0.0177391427332	0.046511627907	GSDMA CASP14	skin; sebaceous cells[>=Low]
HPA:0450612	0.0177391427332	0.046511627907	GSDMA CASP14	skin; sebaceous cells[>=Medium]
HPA:0450613	0.0177391427332	0.046511627907	GSDMA CASP14	skin; sebaceous cells[High]
HPA:0230321	0.0177391427332	0.046511627907	GSDMA CASP14	hair; cells in external root sheath[>=Low]
HP:0040162	0.017966032889	0.0697674418605	CSTA FLG2 DSG1	Orthokeratosis
HPA:0461482	0.0190215640553	0.116279069767	SBSN S100A7 PKP1 CALML3 S100A9	skin 1; sebaceous glands[>=Medium]
HP:0000989	0.0234653525125	0.116279069767	SDR9C7 FLG2 TGM1 ALOX12B PKP1	Pruritus
HP:0011123	0.0237439253779	0.186046511628	ECM1 SDR9C7 DSG1 ALOX12B PKP1 FLG2 CSTA TGM1	Inflammatory abnormality of the skin
TF:M11046	0.0255158384507	0.418604651163	CALML5 S100A9 SERPINB5 ARG1 SERPINA12 TGM3 S100A7A S100A14 PKP1 POF1B CPA4 ASAH1 FLG2 FCGBP S100A7 S100A8 ECM1 TREX2	Factor: CLOCK; motif: NNCAYGYGYN
HP:0025114	0.0308967890865	0.0697674418605	SDR9C7 DSG1 ALOX12B	Hypergranulosis
HP:0001019	0.031816975253	0.093023255814	SDR9C7 TGM1 ALOX12B DSG1	Erythroderma
HP:0008064	0.0387212049006	0.116279069767	SDR9C7 CSTA TGM1 ALOX12B DSG1	Ichthyosis
HP:0000966	0.039027041632	0.093023255814	SDR9C7 TGM1 ALOX12B PKP1	Hypohidrosis
HP:0001596	0.0433496254132	0.139534883721	SDR9C7 TGM3 PKP1 ALOX12B ECM1 TGM1	Alopecia
HPA:0450000	0.049391606064	0.046511627907	GSDMA CASP14	skin

Edges

Protein 1	Protein 2	Score	ProteomeHD	Interface Overlap
ECM1	CPA4	0.997	0.12
DSC1	FLG2	0.997	0.576
DSC1	DSG1	0.996	0.59	structurally_consistent (dimer)
CALML3	GM2A	0.996	0.25
ECM1	ALOX12B	0.995	0.08
CALML3	SERPINB3	0.995	0.286
CALML5	GM2A	0.995	0.098
LCN2	GM2A	0.994	0.054
PKP1	GM2A	0.994	0.03
ECM1	NCCRP1	0.994
ECM1	FLG	0.994	0.116
ECM1	POF1B	0.994	0.114
CSTA	CTSV	0.994	0.158
TREX2	ACP3	0.994
HRNR	DSC1	0.994	0.362
CPA4	CALML5	0.993	0.098
HAL	GM2A	0.993
ECM1	DSG1	0.993	0.166
ECM1	GM2A	0.993	0.034
HRNR	FLG2	0.993	0.456
ECM1	TGM1	0.992	0.26
PPL	CALML3	0.992	0.296
S100A7	GM2A	0.992	0.086
KPRP	FLG	0.992	0.412
DSP	PKP3	0.992	0.538
PPL	EVPL	0.992	0.462
ECM1	CDSN	0.992
SBSN	PKP1	0.992
ECM1	CASP14	0.991	0.26
CPA4	S100A7	0.991	0.076
SERPINB3	LCN2	0.991	0.224
ALOX12B	CPA4	0.991	0.124
ARG1	ECM1	0.991	0.182
S100A7	LCN2	0.991	0.124
CDSN	CPA4	0.991
ECM1	GSDMA	0.991	0.16
ECM1	SERPINB12	0.991	0.192
KPRP	SBSN	0.991
GM2A	POF1B	0.991	0.048
HAL	AZGP1	0.99
TREX2	SBSN	0.99
ALOX12B	SERPINB3	0.99	0.086
ECM1	DSP	0.99	0.394
SBSN	POF1B	0.99
ECM1	AZGP1	0.99	0.274
JUP	CALML3	0.99	0.564
ECM1	DSC1	0.99	0.152
CPA4	FLG	0.99	0.112
ECM1	TGM3	0.99	0.092
CALML5	S100A7	0.99	0.25
CDSN	FLG	0.989
CALML3	EVPL	0.989	0.162
AZGP1	FLG	0.989	0.144
CALML5	GSDMA	0.989	0.16
ALOX12B	S100A8	0.989	0.064
TGM1	CALML3	0.989	0.248
TREX2	SERPINB5	0.989
CALML5	SBSN	0.989
TGM1	CALML5	0.989	0.298	structurally_consistent (Q9NU19)
CPA4	POF1B	0.989	0.072
TGM1	LCN2	0.989	0.184	mutually_exclusive (Q9NU19)
HAL	ALOX12B	0.989
CALML5	LCN2	0.989	0.188	structurally_consistent (Q9NU19)
TREX2	EVPL	0.989
NCCRP1	CSTA	0.989
CALML5	EVPL	0.989	0.18
CDSN	CASP14	0.988
CALML3	S100A7	0.988	0.212
NCCRP1	CPA4	0.988
NCCRP1	SERPINB3	0.988
ECM1	SBSN	0.988
NCCRP1	SERPINA12	0.988
GM2A	FLG	0.988	0.024
CALML3	LCN2	0.988	0.246
PPL	POF1B	0.988	0.146
ALOX12B	AZGP1	0.988	0.126
CPA4	SERPINB3	0.988	0.118
KLK7	POF1B	0.988
ALOX12B	S100A7	0.988	0.058
TGM1	CPA4	0.987	0.242
SERPINB3	GM2A	0.987	0.076
ALOX12B	KLK7	0.987
ALOX12B	POF1B	0.987	0.148
FLG2	SBSN	0.987
TGM1	FLG2	0.987	0.448
CPA4	SBSN	0.987
HAL	FLG	0.987
ALOX12B	CALML5	0.987	0.114	structurally_consistent (Q9NU19)
ALOX12B	SBSN	0.987
KPRP	FLG2	0.987	0.488
ARG1	CPA4	0.987	0.148
CSTA	POF1B	0.987	0.134
SERPINB12	CPA4	0.987	0.114
HAL	DSC1	0.987
GM2A	TGM3	0.987	0.054
GM2A	GSDMA	0.987	0.1
NCCRP1	GM2A	0.987
TGM1	GM2A	0.987	0.042
FLG2	FLG	0.987	0.512
ARG1	SERPINA12	0.987
TREX2	PPL	0.987
SERPINB5	POF1B	0.987	0.064
AZGP1	GM2A	0.986	0.088
KPRP	ECM1	0.986	0.202
S100A7	SERPINB3	0.986	0.396
CALML5	SERPINB3	0.986	0.344
HAL	ECM1	0.986
TYMP	PPL	0.986	0.13
ALOX12B	CDSN	0.986
ALOX12B	NCCRP1	0.986		mutually_exclusive (Q9NU19)
SBSN	SERPINB3	0.986
SBSN	GM2A	0.985
NCCRP1	FLG	0.985
ALOX12B	TGM1	0.985	0.118
JUP	DSC1	0.985	0.564444444444	structurally_consistent (dimer)
ALOX12B	S100A16	0.985	0.078
CPA4	GSDMA	0.985	0.166
FLG2	SERPINA12	0.985
TYMP	EVPL	0.985	0.048
TREX2	S100A7	0.985		structurally_consistent (dimer)
ALOX12B	CSTA	0.985	0.06
CPA4	AZGP1	0.985	0.2
FLG	POF1B	0.985
FLG2	GSDMA	0.985	0.342
ALOX12B	GM2A	0.985	0.088	structurally_consistent (Q9NU19)
CASP14	SBSN	0.985
S100A8	GSDMA	0.985	0.054
CPA4	ZIC1	0.984
ALOX12B	S100A9	0.984	0.106
CALML5	CASP14	0.984	0.21
DSC1	FLG	0.984	0.488
KPRP	CDSN	0.984
FLG	GSDMA	0.984	0.436
ARG1	GM2A	0.984	0.038	structurally_consistent (dimer)
PPL	GM2A	0.984	0.032
FLG	TGM3	0.984	0.432
KLK7	AZGP1	0.984
ECM1	SERPINB3	0.984	0.15
ECM1	SDR9C7	0.984
TGM1	S100A9	0.984	0.124
CDSN	FLG2	0.984
S100A7	FLG	0.984
HAL	KLK7	0.984
KPRP	S100A7	0.984	0.334
HAL	CPA4	0.983
TGM1	FLG	0.983
SBSN	FLG	0.983
ALOX12B	FLG	0.983
SERPINB5	PPL	0.983	0.2
CSTA	GM2A	0.983	0.04	structurally_consistent (P05089)
S100A9	GM2A	0.983	0.044
CALML5	PKP1	0.983	0.162
ARG1	SBSN	0.983
S100A7	CASP14	0.983	0.236
CPA4	GM2A	0.983	0.046
NCCRP1	POF1B	0.983
CPA4	CASP14	0.983	0.272
KLK7	SERPINA12	0.983
CALML5	PKP3	0.983	0.24
ARG1	ALOX12B	0.983	0.154
ALOX12B	FLG2	0.983	0.134
CDSN	AZGP1	0.983
NCCRP1	TGM1	0.983
S100A8	S100A7	0.983	0.096	mutually_exclusive (P06702) structurally_consistent (dimer)
ALOX12B	PKP1	0.982	0.076
S100A7	PKP1	0.982	0.204
ALOX12B	TGM3	0.982	0.138
TGM1	S100A7	0.982	0.232
KPRP	NCCRP1	0.982
ALOX12B	ACP3	0.982	0.07
NCCRP1	FLG2	0.982
POF1B	CTSV	0.982
CALML5	POF1B	0.982	0.124
TGM1	POF1B	0.982	0.106
SERPINB12	FLG	0.982	0.476
ARG1	FLG	0.982	0.474
ARG1	CDSN	0.982
SBSN	DSP	0.982
TGM1	SERPINB3	0.982	0.372
NCCRP1	CALML5	0.982
HAL	CSTA	0.982
ALOX12B	GSDMA	0.982	0.19
ALOX12B	DSC1	0.982	0.142
SERPINB3	GSDMA	0.982	0.18
SDR9C7	ZIC1	0.982
S100A8	CALML5	0.981	0.176086956522
NCCRP1	S100A9	0.981
ARG1	NCCRP1	0.981
S100A9	GSDMA	0.981	0.066
SBSN	AZGP1	0.981
GM2A	CTSV	0.981	0.104	structurally_consistent (Q9NU19)
SBSN	TGM3	0.981
ALOX12B	CASP14	0.981	0.118
CALML5	FLG	0.981
ALOX12B	DSP	0.981	0.118
CDSN	TGM1	0.981
HAL	TGM1	0.981
FLG2	DSG1	0.981	0.428
KPRP	AZGP1	0.981	0.196
NCCRP1	S100A8	0.981		mutually_exclusive (Q9NU19)
NCCRP1	CASP14	0.981
SERPINB3	POF1B	0.98	0.06
S100A7	AZGP1	0.98	0.22
S100A9	S100A7	0.98	0.208	mutually_exclusive (P05109) structurally_consistent (dimer)
DSP	FLG	0.98	0.714
ECM1	CSTA	0.98	0.222
TREX2	S100A9	0.98		mutually_exclusive (P31151)
FLG2	CASP14	0.98	0.526
ALOX12B	SERPINB12	0.98	0.158
NCCRP1	SBSN	0.98
NCCRP1	AZGP1	0.98
PKP1	SERPINB3	0.98	0.344
HAL	CDSN	0.98
CPA4	TGM3	0.98	0.114
ALOX12B	DSG1	0.98	0.142
HAL	CALML5	0.98
CDSN	DSP	0.98
DSG1	FLG	0.98	0.338
NCCRP1	DSP	0.98
TGM1	GSDMA	0.98	0.296
DSC1	SBSN	0.98
S100A16	GM2A	0.979	0.082
ARG1	POF1B	0.979	0.142
ARG1	FLG2	0.979	0.536
FLG2	AZGP1	0.979	0.352
CASP14	FLG	0.979
CPA4	PKP1	0.979	0.09
S100A16	POF1B	0.979	0.03
S100A14	S100A16	0.979	0.0915
TGM1	KLK7	0.979
SERPINB12	GM2A	0.979	0.038	mutually_exclusive (P05089)
CALML5	S100A9	0.979	0.256
SBSN	DSG1	0.979
ARG1	HAL	0.979
TREX2	CSTA	0.978
S100A7	GSDMA	0.978	0.132
NCCRP1	PKP1	0.978
S100A8	POF1B	0.978	0.0740869565217
CDSN	HRNR	0.978
KPRP	ALOX12B	0.978	0.176
DSG1	CSTA	0.978	0.2
NCCRP1	GSDMA	0.978
SERPINB12	FLG2	0.978	0.468
NCCRP1	ACP3	0.978
S100A8	GM2A	0.978	0.054
TREX2	CALML5	0.978
CPA4	SDR9C7	0.978
HAL	CASP14	0.978
NCCRP1	KLK7	0.978
CPA4	CSTA	0.978	0.184
TGM1	SBSN	0.978
TGM1	SERPINA12	0.978
S100A7	CSTA	0.978	0.364	structurally_consistent (P05089)
SERPINB5	ACP3	0.978	0.148
CSTA	FLG	0.978	0.32
CPA4	CTSV	0.978	0.128
TYMP	SERPINB5	0.977	0.118
AZGP1	TGM3	0.977	0.22
S100A16	GSDMA	0.977	0.058
FLG2	TGM3	0.977	0.438
POF1B	GSDMA	0.977	0.13
NCCRP1	DSC1	0.977
ASAH1	ALOX12B	0.977	0.07
S100A7	POF1B	0.977	0.086
S100A9	POF1B	0.977	0.086
CASP14	ZIC1	0.977
ACP3	CTSV	0.977
SERPINB3	ACP3	0.977	0.088
CPA4	S100A8	0.977	0.072
CDSN	TGM3	0.977
NCCRP1	S100A16	0.976
CDSN	SBSN	0.976
KLK7	GSDMA	0.976
S100A7A	EVPL	0.976
ZIC1	GSDMA	0.976
NCCRP1	DSG1	0.976
ALOX12B	JUP	0.976	0.166
TYMP	CALML3	0.976	0.178
SERPINB12	CALML5	0.975	0.184333333333
TGM1	CASP14	0.975	0.44
CDSN	DSC1	0.975
NCCRP1	JUP	0.975
CDSN	GM2A	0.975
HAL	GSDMA	0.975
HAL	TGM3	0.975
ARG1	KLK7	0.975
HAL	SBSN	0.975
CASP14	TGM3	0.975	0.438
SERPINB3	TGM3	0.975	0.526
EVPL	FCGBP	0.975
ACP3	GM2A	0.975	0.068
S100A7	ACP3	0.975	0.058
ARG1	SDR9C7	0.975
KLK7	SBSN	0.975
S100A7	S100A16	0.974	0.112
KIR3DS1	CALML5	0.974
PKP1	POF1B	0.974	0.056
KIR3DS1	FLG	0.974
SBSN	GSDMA	0.974
CALML5	CSTA	0.974	0.498
TGM1	S100A8	0.974	0.108
CDSN	DSG1	0.974
DSC1	TGM3	0.974	0.484
TREX2	S100A7A	0.974
ACP3	PKP3	0.974	0.106
NCCRP1	CALML3	0.974
CDSN	NCCRP1	0.973
SERPINB3	FLG	0.973	0.244
PPL	CALML5	0.973	0.334
HAL	NCCRP1	0.973
NCCRP1	S100A7	0.973
TYMP	FCGBP	0.973	0.068
CPA4	S100A9	0.973	0.07
S100A8	LCN2	0.973	0.262	mutually_exclusive (Q9NU19)
S100A11	CALML5	0.973	0.202
TYMP	PKP1	0.973	0.096
CASP14	POF1B	0.973	0.132
KPRP	PKP1	0.973	0.172
CDSN	POF1B	0.972
PKP1	FLG	0.972
SERPINB12	CDSN	0.972
TYMP	DSP	0.972	0.24
ECM1	FLG2	0.972	0.19
CDSN	GSDMA	0.972
ECM1	CTSV	0.972	0.132
KPRP	POF1B	0.972	0.106
KPRP	GSDMA	0.972	0.228
SERPINB12	NCCRP1	0.972
TGM1	PKP3	0.971	0.264
HAL	POF1B	0.971
TGM1	S100A16	0.971	0.076
HAL	SERPINB3	0.971
LCN2	FCGBP	0.971	0.162
S100A14	SERPINA12	0.971
KPRP	DSP	0.971	0.602
TREX2	CALML3	0.971
GM2A	FCGBP	0.971	0.006
NCCRP1	TGM3	0.97
DSG1	SDR9C7	0.97
HAL	FLG2	0.97
CALML3	PKP1	0.969	0.188
JUP	FLG	0.969	0.702
SDR9C7	FLG	0.969
CDSN	JUP	0.969
KLK7	CPA4	0.969
SERPINB5	PKP3	0.969	0.256
KLK7	FLG2	0.968
KPRP	HAL	0.968
HAL	DSP	0.968
ECM1	CALML5	0.968	0.180333333333
CASP14	GM2A	0.968	0.046
TREX2	CTSV	0.968
TGM1	ACP3	0.968	0.12
NCCRP1	PPL	0.968
S100A9	FLG	0.968	0.202
ACP3	POF1B	0.968	0.078
SERPINB5	CALML3	0.967	0.266
AZGP1	ACP3	0.967	0.096
KLK7	CASP14	0.967
ARG1	TGM1	0.967	0.378
TGM3	POF1B	0.967	0.166
PKP1	PKP3	0.967	0.146
EVPL	GM2A	0.967	0.022
TREX2	PKP1	0.967
ARG1	CSTA	0.967	0.34	structurally_consistent (dimer)
S100A7A	S100A7	0.967
S100A7A	S100A9	0.967
PPL	FCGBP	0.966
ACP3	GSDMA	0.966	0.07
S100A8	FLG	0.966	0.116086956522
CALML5	S100A7A	0.966
SERPINB12	S100A7	0.966	0.2
GM2A	ZIC1	0.966
KPRP	ARG1	0.966	0.384
KPRP	CSTA	0.966	0.232
S100A8	SERPINB3	0.966	0.158
S100A16	SDR9C7	0.966
S100A7	ZIC1	0.966
KPRP	CASP14	0.965	0.6
EVPL	POF1B	0.965	0.202
AZGP1	SERPINB3	0.965	0.24
PKP1	GSDMA	0.965	0.156
TREX2	PKP3	0.964
SERPINB3	ZIC1	0.964
ALOX12B	SDR9C7	0.964
SDR9C7	CTSV	0.964
KLK7	DSP	0.964
FLG2	CSTA	0.964	0.262
ARG1	GSDMA	0.964	0.336
TGM1	DSP	0.964	0.598
TGM1	DSC1	0.964	0.398	mutually_exclusive (P14923)
AZGP1	GSDMA	0.964	0.17
HRNR	DSG1	0.964	0.352
TGM1	AZGP1	0.964	0.128
DSC1	GSDMA	0.964	0.264
AZGP1	POF1B	0.964	0.126
ALOX12B	SERPINA12	0.964
CALML3	PKP3	0.963	0.186
DSG1	GSDMA	0.963	0.392
PPL	PKP3	0.963	0.208
TREX2	S100A8	0.962		mutually_exclusive (P31151)
ALOX12B	CTSV	0.962		mutually_exclusive (Q9NU19)
CALML5	TGM3	0.962	0.312	structurally_consistent (Q9NU19)
AZGP1	ZIC1	0.962
KLK7	PKP1	0.962
S100A8	S100A7A	0.962
SERPINB5	EVPL	0.962	0.196
AZGP1	CSTA	0.962	0.192
ACP3	FCGBP	0.962
TREX2	GM2A	0.962
S100A7	DSG1	0.962	0.246
S100A9	LCN2	0.962	0.228
S100A7	TGM3	0.962	0.346
TREX2	S100A11	0.961
KPRP	TGM1	0.961	0.55
KPRP	DSC1	0.961	0.616
LCN2	POF1B	0.961	0.092
S100A14	LCN2	0.961	0.13
POF1B	PKP3	0.961	0.234
ASAH1	GSDMA	0.961	0.044
S100A9	SBSN	0.961
CALML3	POF1B	0.961	0.182
SERPINB5	CALML5	0.96	0.124
KLK7	FLG	0.96
ECM1	KLK7	0.96
EVPL	DSP	0.96	0.172
DSG1	TGM3	0.96	0.354
ECM1	S100A9	0.96	0.09
HAL	SERPINB12	0.96
CALML3	ACP3	0.959	0.16
KPRP	SERPINB3	0.959	0.236
KPRP	KLK7	0.959
TGM3	PKP3	0.959	0.216
ASAH1	NCCRP1	0.959
CPA4	CALML3	0.959	0.274
PKP1	ACP3	0.959	0.08
CDSN	PKP1	0.959
SERPINB12	TGM3	0.959	0.418
S100A11	GM2A	0.958	0.044
JUP	PKP1	0.958	0.354
DSC1	PKP1	0.958	0.186
S100A8	ACP3	0.958	0.064
DSP	SDR9C7	0.957
SERPINB12	HRNR	0.957	0.278
S100A16	SERPINB3	0.957	0.12
S100A16	ACP3	0.957	0.08
ECM1	SERPINA12	0.956
CALML3	S100A9	0.956	0.228
ECM1	PKP1	0.956	0.13
S100A9	ACP3	0.956	0.088
TGM1	GGCT	0.956	0.096
CALML3	CALML5	0.956	0.29
KLK7	CTSV	0.956
S100A8	CSTA	0.956	0.256
S100A11	POF1B	0.955	0.1
S100A9	SERPINB3	0.955	0.227
ASAH1	TGM1	0.955	0.064
CALML5	AZGP1	0.955	0.226
S100A8	CALML3	0.955	0.17
TGM1	CSTA	0.955	0.312
TGM1	S100A14	0.955	0.106
NCCRP1	S100A14	0.955
TREX2	SERPINB3	0.955
S100A9	ZIC1	0.954
CDSN	CALML5	0.954
TREX2	LCN2	0.954		structurally_consistent (dimer)
SDR9C7	GM2A	0.954
TREX2	GGCT	0.954
SERPINB5	FCGBP	0.954
DSC1	AZGP1	0.953	0.212
S100A7	FCGBP	0.953
TYMP	TREX2	0.953
LCN2	CTSV	0.953	0.19
SBSN	CSTA	0.953
CALML5	DSC1	0.953	0.278
CASP14	AZGP1	0.953	0.276
SDR9C7	GSDMA	0.953
SBSN	SERPINA12	0.952
CALML3	FCGBP	0.952
TYMP	GM2A	0.952	0.028
KIR3DS1	S100A8	0.952
NCCRP1	PKP3	0.952
CTSV	ZIC1	0.952
FLG2	PKP1	0.952	0.174
PPL	PKP1	0.952	0.19
EVPL	PKP1	0.952	0.206
CALML5	FCGBP	0.952
SERPINB12	AZGP1	0.952	0.298
FCGBP	GSDMA	0.952
DSP	FCGBP	0.952	0.086
KLK7	DSC1	0.952
CDSN	KLK7	0.951
HAL	FCGBP	0.951
PKP1	DSP	0.951	0.444
GGCT	EVPL	0.951	0.052
SERPINB12	TGM1	0.951	0.328
KLK7	DSG1	0.951
JUP	FLG2	0.951	0.558
HAL	SERPINA12	0.95
ARG1	AZGP1	0.95	0.216
KPRP	DSG1	0.95	0.628
NCCRP1	LCN2	0.95
DSC1	CASP14	0.95	0.462
CASP14	DSG1	0.95	0.358
AZGP1	DSG1	0.95	0.242
TGM1	DSG1	0.949	0.378
PKP1	DSG1	0.949	0.156
PPL	ACP3	0.949	0.1
JUP	CASP14	0.949	0.56
SERPINB12	POF1B	0.949	0.174
SDR9C7	CSTA	0.948
SERPINB12	S100A8	0.948	0.166
SERPINB12	GSDMA	0.948	0.346
ARG1	PKP1	0.948	0.18
TREX2	TGM3	0.948
S100A14	CALML3	0.948	0.22
EVPL	PKP3	0.948	0.23
CASP14	CSTA	0.948	0.524
ARG1	CASP14	0.948	0.446
ARG1	SERPINB12	0.948	0.464	structurally_consistent (dimer)
TYMP	S100A7A	0.947
SERPINB12	CSTA	0.947	0.242	structurally_consistent (P05089)
DSP	GM2A	0.947	0.036
CSTA	SERPINB3	0.947	0.458
CASP14	GSDMA	0.946	0.478
CDSN	S100A7	0.946
AZGP1	CTSV	0.946	0.114
JUP	SBSN	0.946
S100A7	DSP	0.946	0.666
ARG1	CALML5	0.946	0.176
ACP3	TGM3	0.946	0.102
SERPINB3	CTSV	0.946	0.106
FLG2	POF1B	0.946	0.086
TGM1	PKP1	0.945	0.27
ECM1	S100A14	0.945	0.086
S100A7A	SERPINB3	0.945
NCCRP1	EVPL	0.945
DSP	ACP3	0.945	0.136
SERPINB12	DSC1	0.945	0.51
ARG1	DSC1	0.945	0.418
DSC1	DSP	0.945	0.614
PKP1	TGM3	0.945	0.188
TGM1	EVPL	0.945	0.182
SERPINB3	FCGBP	0.945
TGM1	ZIC1	0.944
S100A8	SBSN	0.944
TGM1	SDR9C7	0.944
DSC1	POF1B	0.944	0.166
SERPINB12	DSG1	0.943	0.474
SERPINB12	SERPINA12	0.943
TYMP	TGM1	0.943	0.076
HAL	DSG1	0.943
EVPL	SBSN	0.942
NCCRP1	TREX2	0.942
HAL	PKP1	0.942
CPA4	ACP3	0.942	0.074
CALML3	DSP	0.941	0.722
CASP14	SERPINB3	0.941	0.28
KPRP	S100A8	0.941	0.120086956522
TYMP	PKP3	0.941	0.048
PPL	SBSN	0.941
SDR9C7	ACP3	0.941
SERPINA12	FLG	0.941
ARG1	ZIC1	0.941
TGM3	CTSV	0.941	0.102	mutually_exclusive (Q9NU19)
KPRP	ACP3	0.94	0.12
KPRP	SDR9C7	0.94
KPRP	SERPINB12	0.94	0.526
JUP	TGM1	0.94	0.564701754386	structurally_consistent (dimer)
AZGP1	SERPINA12	0.94
FLG2	DSP	0.94	0.648
EVPL	SERPINB3	0.94	0.134
PKP1	FCGBP	0.94
TREX2	AZGP1	0.939
ALOX12B	ZIC1	0.939
FLG2	ZIC1	0.939
TREX2	POF1B	0.939
TGM1	CTSV	0.939
TGM1	PPL	0.938	0.188
TREX2	FCGBP	0.937
DSG1	POF1B	0.937	0.174
TYMP	POF1B	0.937	0.038
DSP	CTSV	0.937	0.17
LCN2	ACP3	0.937	0.172
ARG1	S100A7	0.937	0.274	structurally_consistent (dimer)
S100A9	CSTA	0.936	0.226
TYMP	SBSN	0.936
CDSN	CSTA	0.936
S100A7A	SBSN	0.936
TYMP	KLK7	0.935
S100A8	S100A9	0.935	0.47	mutually_exclusive (P31151) structurally_consistent (dimer)
ASAH1	S100A14	0.935	0.068
TREX2	DSP	0.935
KPRP	CTSV	0.934	0.172
CASP14	SDR9C7	0.934
TGM1	TGM3	0.934	0.522	mutually_exclusive (Q9NU19)
S100A14	ACP3	0.934	0.094
TYMP	JUP	0.934	0.19
S100A14	SDR9C7	0.934
S100A8	PPL	0.933	0.086
DSC1	SERPINA12	0.933
SERPINB12	DSP	0.933	0.606
S100A8	CASP14	0.932	0.046
AZGP1	PKP1	0.932	0.17
KPRP	JUP	0.932	0.598
ECM1	S100A16	0.932	0.038
NCCRP1	CTSV	0.932
CALML5	DSG1	0.932	0.268
S100A16	SERPINA12	0.931
SERPINB12	CASP14	0.931	0.592
PKP1	SDR9C7	0.931
ARG1	TREX2	0.93
SERPINB12	SBSN	0.93
S100A14	GM2A	0.93	0.07
ARG1	DSG1	0.93	0.362
S100A14	KLK7	0.93
JUP	S100A7	0.93	0.486666666667
S100A8	CTSV	0.93	0.064	mutually_exclusive (Q9NU19)
S100A9	FLG2	0.93	0.226
SERPINB12	JUP	0.929	0.486666666667
ALOX12B	CALML3	0.929	0.134
JUP	DSP	0.929	0.518
JUP	POF1B	0.929	0.402525641026
HRNR	CSTA	0.928	0.224
KLK7	SERPINB3	0.928
PPL	S100A7A	0.928
HAL	TREX2	0.928
CASP14	PKP1	0.928	0.254
S100A9	CTSV	0.928	0.09
NCCRP1	FCGBP	0.928
CTSV	GSDMA	0.928	0.106
CASP14	DSP	0.928	0.652
AZGP1	SDR9C7	0.928
KIR3DS1	S100A9	0.927
NCCRP1	SDR9C7	0.927
S100A9	CASP14	0.926	0.232
SERPINB12	S100A9	0.926	0.216
LCN2	GSDMA	0.926	0.104
S100A8	FCGBP	0.925	0.182
SERPINA12	GSDMA	0.925
ARG1	JUP	0.924	0.304704225352
S100A9	TGM3	0.924	0.192
S100A9	FCGBP	0.924	0.312
KLK7	S100A16	0.924
PPL	SERPINB3	0.924	0.236
ARG1	S100A16	0.924	0.120625
CSTA	TGM3	0.924	0.436
CALML5	ACP3	0.923	0.114
ECM1	S100A8	0.923	0.048
KLK7	SDR9C7	0.923
CASP14	ACP3	0.923	0.072
ARG1	CTSV	0.923	0.16
S100A14	S100A7	0.923	0.092
PPL	S100A9	0.923	0.092
SERPINB12	SERPINB3	0.923	0.234
TYMP	LCN2	0.922	0.222
S100A8	TGM3	0.922	0.112
TYMP	NCCRP1	0.922
S100A7	CTSV	0.922
NCCRP1	S100A7A	0.922
S100A8	FLG2	0.921	0.11
S100A8	AZGP1	0.921	0.206
ARG1	TGM3	0.92	0.358
TYMP	CALML5	0.92	0.13
CALML3	CTSV	0.92	0.18
ASAH1	SDR9C7	0.92
KPRP	CPA4	0.92	0.13
AZGP1	LCN2	0.919	0.28525
SERPINB5	GM2A	0.919	0.024
S100A8	PKP1	0.919	0.136
TGM1	FCGBP	0.918
CSTA	GSDMA	0.918	0.2
ALOX12B	S100A14	0.918	0.068
S100A14	PKP3	0.917	0.194
CDSN	SERPINA12	0.915
CALML3	S100A7A	0.915
S100A14	FLG	0.915	0.174
KPRP	S100A9	0.915	0.182
POF1B	FCGBP	0.914	0.086
DSG1	CTSV	0.914	0.19
KIR3DS1	CALML3	0.914
SERPINB5	PKP1	0.914	0.176
KLK7	PPL	0.914
TYMP	SERPINB3	0.914	0.118
CPA4	FLG2	0.914	0.09
TGM3	GSDMA	0.914	0.31
SBSN	PKP3	0.914
KIR3DS1	S100A7	0.914
EVPL	ACP3	0.913	0.102
AZGP1	DSP	0.913	0.316
S100A16	CTSV	0.913	0.086
ALOX12B	LCN2	0.913	0.15	mutually_exclusive (Q9NU19)
SBSN	SDR9C7	0.913
KLK7	TGM3	0.912
JUP	S100A14	0.912	0.496
ARG1	SERPINB3	0.912	0.248
SDR9C7	POF1B	0.912
HAL	S100A8	0.911
S100A9	DSG1	0.911	0.148
GM2A	PKP3	0.911	0.032
SDR9C7	TGM3	0.91
KIR3DS1	POF1B	0.91
S100A8	EVPL	0.91	0.086
S100A8	DSG1	0.909	0.102
CDSN	CTSV	0.909
S100A14	SBSN	0.909
SERPINB12	PKP1	0.909	0.144
DSG1	SERPINA12	0.908
PPL	GSDMA	0.908	0.18
SERPINB5	TGM3	0.908	0.11
S100A14	GSDMA	0.906	0.08
S100A16	LCN2	0.906	0.058
CSTA	ZIC1	0.906
TYMP	S100A8	0.906	0.284
SERPINB5	GSDMA	0.905	0.07
SERPINB3	PKP3	0.904	0.442
KLK7	GM2A	0.904
TYMP	ACP3	0.904	0.044
KPRP	SERPINA12	0.902
FCGBP	CTSV	0.902
PKP1	CSTA	0.902	0.306
S100A14	S100A8	0.902	0.092
FLG2	SDR9C7	0.902
S100A7	SBSN	0.902
DSP	TGM3	0.9	0.62
HAL	PPL	0.9
S100A16	AZGP1	0.9	0.054
CDSN	SDR9C7	0.9
TYMP	DSC1	0.899	0.096
DSP	CSTA	0.899	0.46
JUP	ACP3	0.899	0.162
S100A14	DSP	0.898	0.456
DSG1	SERPINB3	0.898	0.174
S100A9	PKP1	0.897	0.19
KPRP	S100A14	0.897	0.06
KLK7	LCN2	0.897
KPRP	CALML5	0.897	0.122
SERPINB12	KLK7	0.897
CALML5	S100A16	0.897	0.17087163953
SDR9C7	SERPINB3	0.896
CPA4	SERPINA12	0.896
ASAH1	ACP3	0.895	0.156
KPRP	TYMP	0.895	0.054
HAL	CTSV	0.894
ARG1	S100A8	0.894	0.138
TYMP	S100A16	0.894	0.086
HAL	SERPINB5	0.894
JUP	AZGP1	0.893	0.234666666667
CASP14	CTSV	0.892
S100A7	FLG2	0.892	0.24
ARG1	HRNR	0.891	0.36
TREX2	CPA4	0.891
S100A9	EVPL	0.891	0.07
ALOX12B	PKP3	0.89	0.120357142857
ECM1	ZIC1	0.89
JUP	S100A8	0.89	0.158
ARG1	S100A14	0.89	0.092
S100A16	ZIC1	0.89
DSC1	CSTA	0.889	0.31
S100A14	CPA4	0.889	0.12296
JUP	PKP3	0.889	0.462
S100A9	AZGP1	0.889	0.28
PPL	DSP	0.889	0.398
JUP	KLK7	0.888
S100A14	CSTA	0.888	0.238
S100A7A	LCN2	0.888
PPL	CTSV	0.888	0.162
SERPINB5	LCN2	0.888	0.19
EVPL	LCN2	0.887	0.14
SERPINB5	CTSV	0.886	0.142
CDSN	S100A8	0.886
CDSN	SERPINB3	0.886
S100A14	AZGP1	0.886	0.108
CPA4	DSC1	0.885	0.116
KLK7	CALML3	0.885
S100A14	POF1B	0.884	0.12
JUP	TGM3	0.884	0.656
S100A9	DSP	0.884	0.16
TYMP	S100A9	0.883	0.232
ASAH1	ECM1	0.883	0.074
CALML3	DSC1	0.882	0.148
CSTA	ACP3	0.882	0.086
S100A14	FLG2	0.881	0.066
S100A14	TGM3	0.88	0.05
S100A14	CALML5	0.88	0.176
SERPINB12	SDR9C7	0.879
ECM1	S100A7	0.879	0.098
HAL	JUP	0.879
TREX2	S100A16	0.879
TYMP	S100A7	0.879	0.086
HAL	S100A9	0.877
DSP	POF1B	0.876	0.3556
PKP1	CTSV	0.876
CDSN	S100A16	0.876
ECM1	CALML3	0.875	0.226
KPRP	TGM3	0.875	0.43
S100A8	DSC1	0.874	0.0980869565217
TREX2	GSDMA	0.874
SERPINB5	FLG	0.874	0.116
FLG2	SERPINB3	0.874	0.342
CALML3	S100A16	0.874	0.256548387097
CALML3	SBSN	0.873
DSP	SERPINB3	0.873	0.52
ACP3	FLG	0.871
DSP	GSDMA	0.871	0.506
ASAH1	CPA4	0.871	0.078
DSG1	GM2A	0.87	0.05
NCCRP1	SERPINB5	0.87
CPA4	DSG1	0.868	0.146
CDSN	TREX2	0.867
SERPINB5	SERPINB3	0.866	0.224
S100A11	EVPL	0.866	0.096
SBSN	CTSV	0.866
NCCRP1	HRNR	0.865
DSC1	SERPINB3	0.863	0.324
FLG	CTSV	0.863	0.13
DSP	LCN2	0.862	0.398
JUP	S100A9	0.86	0.154
TGM1	S100A7A	0.859		structurally_consistent (Q9NU19)
S100A14	PKP1	0.858	0.096
S100A14	PPL	0.858	0.072
TGM1	SERPINB5	0.857	0.198
SERPINB5	DSP	0.856	0.410571428571
S100A8	ZIC1	0.855
HAL	S100A7A	0.853
TYMP	TGM3	0.852	0.052
SERPINA12	TGM3	0.852
S100A7	EVPL	0.851	0.108
SERPINA12	CTSV	0.851
ASAH1	AZGP1	0.851	0.082
S100A14	CASP14	0.849	0.084
TREX2	DSG1	0.849
HAL	S100A16	0.849
ARG1	CALML3	0.848	0.188
CASP14	SERPINA12	0.847
S100A11	S100A16	0.845	0.194
S100A7	DSC1	0.845	0.232
CALML3	GSDMA	0.844	0.104
JUP	CALML5	0.843	0.536
KLK7	KIR3DS1	0.843
KLK7	CSTA	0.842
ECM1	JUP	0.841	0.324625
CPA4	S100A11	0.841	0.1
S100A14	FCGBP	0.84	0.038
TREX2	DSC1	0.839
JUP	DSG1	0.839	0.594	structurally_consistent (Q08554)
S100A14	SERPINB3	0.838	0.192
JUP	GSDMA	0.837	0.478
S100A14	DSC1	0.835	0.152
DSP	DSG1	0.834	0.594
S100A14	S100A9	0.834	0.086
HAL	LCN2	0.834
KLK7	CALML5	0.833
TREX2	CASP14	0.832
KPRP	PPL	0.831	0.344
KLK7	S100A7	0.831
SERPINB5	S100A9	0.83	0.11
S100A9	SDR9C7	0.83
S100A8	SDR9C7	0.83
KIR3DS1	AZGP1	0.828
CALML5	FLG2	0.827	0.146
SERPINB5	SBSN	0.826
SERPINA12	POF1B	0.826
ECM1	ACP3	0.825	0.078
PPL	S100A7	0.825	0.254
SERPINB12	ACP3	0.825	0.098
S100A11	CALML3	0.824	0.204
HAL	CALML3	0.824
SDR9C7	SERPINA12	0.823
KPRP	ASAH1	0.823	0.112
KPRP	PKP3	0.822	0.208
CALML3	TGM3	0.821	0.12
CALML3	DSG1	0.82	0.154
HAL	EVPL	0.817
KLK7	S100A8	0.817
CALML5	CTSV	0.816
S100A9	DSC1	0.812	0.122
S100A16	EVPL	0.812	0.06
S100A11	FCGBP	0.811	0.082
KLK7	TREX2	0.811
TREX2	FLG	0.811
JUP	GM2A	0.808	0.066
GGCT	CASP14	0.807	0.178
CDSN	KIR3DS1	0.806
DSC1	ACP3	0.804	0.056
FLG2	GM2A	0.802	0.068
TYMP	HAL	0.801
HAL	ACP3	0.801
SERPINB12	S100A14	0.801	0.074
KLK7	S100A9	0.8
S100A8	DSP	0.798	0.114
SERPINB5	S100A7	0.798	0.126
DSG1	ACP3	0.796	0.066
S100A9	S100A16	0.796	0.078
SERPINB5	CASP14	0.795	0.11
S100A16	DSP	0.792	0.062
KPRP	GM2A	0.792	0.086
KLK7	ACP3	0.79
FLG2	CTSV	0.79	0.074
S100A14	HRNR	0.789	0.088
S100A16	FLG	0.787	0.104
HAL	S100A7	0.787
HRNR	PKP1	0.787	0.102
S100A14	DSG1	0.786	0.074
SERPINB12	TREX2	0.782
KPRP	HRNR	0.78	0.41
CALML3	CASP14	0.779	0.144
S100A14	EVPL	0.775	0.11
KIR3DS1	SERPINB3	0.774
S100A16	SBSN	0.773
PPL	LCN2	0.772	0.208
SERPINB5	S100A16	0.77	0.036
SERPINB5	SERPINA12	0.769
HAL	S100A14	0.769
CPA4	PKP3	0.768	0.152
SERPINB5	S100A7A	0.768
S100A7A	S100A16	0.767
TGM1	TREX2	0.767
S100A11	LCN2	0.766	0.178
TYMP	CTSV	0.766	0.132
S100A11	GSDMA	0.766	0.1
TYMP	DSG1	0.763	0.096
KPRP	TREX2	0.762
KPRP	S100A16	0.762	0.116
S100A16	PKP1	0.76	0.032
EVPL	TGM3	0.759	0.106
ALOX12B	S100A11	0.759	0.076
HAL	SDR9C7	0.759
CALML3	FLG	0.758	0.164
EVPL	CTSV	0.757	0.158
S100A8	S100A16	0.757	0.068
SDR9C7	FCGBP	0.756
PPL	TGM3	0.756	0.208
ALOX12B	GGCT	0.756	0.062
S100A14	KIR3DS1	0.755
FLG2	ACP3	0.754	0.07
TYMP	GSDMA	0.752	0.05
KIR3DS1	CTSV	0.751
JUP	SERPINB3	0.75	0.466
SERPINB12	PPL	0.749	0.222
S100A11	PPL	0.748	0.072
ALOX12B	FCGBP	0.746
ARG1	FCGBP	0.746	0.036
TREX2	SDR9C7	0.745
TGM3	FCGBP	0.744
SERPINB5	DSG1	0.743	0.098
NCCRP1	ZIC1	0.743
JUP	ZIC1	0.742
S100A7A	FLG	0.732
NCCRP1	S100A11	0.732
S100A8	SERPINB5	0.73	0.136
SBSN	ACP3	0.726
GGCT	FCGBP	0.724	0.01
CASP14	FCGBP	0.723
CDSN	CALML3	0.722
LCN2	FLG	0.722	0.116
CPA4	S100A16	0.72	0.102
CDSN	SERPINB5	0.719
LCN2	TGM3	0.715	0.122
CPA4	DSP	0.715	0.3456
CDSN	S100A14	0.712
GGCT	POF1B	0.711	0.024
KIR3DS1	LCN2	0.711		structurally_consistent (dimer)
PKP1	SERPINA12	0.71
JUP	CSTA	0.71	0.43
KPRP	FCGBP	0.707
HAL	ZIC1	0.705
KLK7	EVPL	0.698
S100A14	CTSV	0.698	0.098
JUP	S100A16	0.697	0.0945022421525
NCCRP1	GGCT	0.692
CPA4	SERPINB5	0.691	0.126
GGCT	ZIC1	0.691
S100A16	PKP3	0.689	0.092
SERPINA12	GM2A	0.688
JUP	HRNR	0.688	0.49
SBSN	FCGBP	0.687
ECM1	HRNR	0.687	0.106
SERPINB12	CTSV	0.685	0.102
S100A7A	FCGBP	0.685
CPA4	FCGBP	0.681
AZGP1	FCGBP	0.672	0.112
ALOX12B	SERPINB5	0.672	0.0833333333333
S100A14	SERPINB5	0.671	0.162
S100A11	SERPINB3	0.667	0.04
KIR3DS1	DSC1	0.667
SBSN	LCN2	0.666
EVPL	GSDMA	0.665	0.076
TYMP	S100A14	0.663	0.078
TGM1	S100A11	0.662	0.108
S100A11	S100A7	0.661	0.044
ARG1	DSP	0.66	0.482
JUP	FCGBP	0.66	0.09
KLK7	SERPINB5	0.66
S100A7A	CTSV	0.659
CASP14	LCN2	0.656	0.118
CALML5	DSP	0.655	0.642
CALML3	CSTA	0.653	0.354
CPA4	LCN2	0.652	0.14	mutually_exclusive (Q9NU19)
DSC1	PKP3	0.65	0.2545
PPL	FLG	0.646	0.312
SERPINB12	CALML3	0.645	0.142
KIR3DS1	CASP14	0.643
FLG	FCGBP	0.642
EVPL	FLG	0.642	0.08
DSC1	SDR9C7	0.639
SERPINB12	FCGBP	0.637
TYMP	CDSN	0.637
ASAH1	S100A16	0.635	0.052
S100A11	S100A9	0.634	0.154
SERPINB12	S100A16	0.63	0.046
ARG1	ACP3	0.63	0.132
KPRP	CALML3	0.629	0.116
PPL	AZGP1	0.627	0.134
CSTA	FCGBP	0.626
FLG	ZIC1	0.625
SDR9C7	LCN2	0.625
CALML5	ZIC1	0.624
S100A14	ZIC1	0.623
CDSN	PKP3	0.616
KLK7	PKP3	0.614
S100A7A	TGM3	0.61		structurally_consistent (Q9NU19)
S100A7	SDR9C7	0.609
CSTA	SERPINA12	0.608
DSC1	GM2A	0.607	0.042
KLK7	ZIC1	0.605
S100A16	CASP14	0.604	0.068
SERPINB5	DSC1	0.601	0.124
S100A7A	ACP3	0.6
JUP	CTSV	0.598	0.208
TYMP	FLG2	0.593	0.082
ASAH1	CSTA	0.59	0.106
S100A7A	GM2A	0.589		structurally_consistent (Q9NU19)
S100A7A	POF1B	0.589
S100A16	TGM3	0.589	0.15
JUP	EVPL	0.586	0.18225
KIR3DS1	DSP	0.584
TREX2	SERPINA12	0.577
KLK7	S100A7A	0.575
KLK7	FCGBP	0.573
PKP3	FCGBP	0.573	0.036
S100A16	FCGBP	0.572	0.006
S100A16	FLG2	0.571	0.06
S100A7A	CSTA	0.568
S100A11	PKP3	0.567	0.062
ARG1	SERPINB5	0.567	0.128
HAL	GGCT	0.566
S100A7A	DSP	0.562
ALOX12B	S100A7A	0.562		structurally_consistent (Q9NU19)
S100A7A	CASP14	0.562
S100A7A	PKP3	0.562
GGCT	GSDMA	0.559	0.074
S100A7A	PKP1	0.558
CASP14	PKP3	0.556	0.226
ASAH1	SBSN	0.556
GGCT	SERPINB3	0.553	0.042
SERPINB5	AZGP1	0.551	0.104
KIR3DS1	GM2A	0.551
DSC1	CTSV	0.55	0.12
KIR3DS1	GSDMA	0.547
TYMP	AZGP1	0.545	0.126
ARG1	S100A11	0.544	0.102
S100A11	S100A8	0.543	0.218
SERPINB5	CSTA	0.543	0.336
S100A16	CSTA	0.541	0.132
KPRP	ZIC1	0.539
TYMP	ALOX12B	0.539	0.074
ASAH1	TGM3	0.537	0.082
HRNR	DSP	0.536	0.488
SERPINB12	PKP3	0.536	0.274
TYMP	S100A11	0.535	0.152857142857
DSG1	FCGBP	0.527
ARG1	S100A7A	0.524
PPL	DSG1	0.524	0.192
EVPL	CSTA	0.524	0.108
S100A11	CASP14	0.522	0.052
JUP	TREX2	0.52
S100A14	TREX2	0.518
PPL	SDR9C7	0.518
ALOX12B	PPL	0.517	0.22
SERPINB5	SDR9C7	0.516
SERPINA12	ACP3	0.515
TYMP	CSTA	0.513	0.126
S100A7A	SDR9C7	0.512
PPL	DSC1	0.51	0.274
S100A7A	GSDMA	0.51
EVPL	DSG1	0.509	0.104
PKP1	LCN2	0.505	0.132
S100A7A	AZGP1	0.5
TYMP	SERPINA12	0.498
CPA4	EVPL	0.498	0.088
PPL	S100A16	0.494	0.064
ARG1	PKP3	0.494	0.214
CALML3	FLG2	0.494	0.104
S100A9	SERPINA12	0.493
ASAH1	CASP14	0.491	0.096
TYMP	SERPINB12	0.491	0.036
ARG1	S100A9	0.489	0.13
SERPINB12	ZIC1	0.487
TYMP	CASP14	0.487	0.056
JUP	LCN2	0.486	0.424
HAL	S100A11	0.482
ECM1	LCN2	0.478	0.094
GGCT	TGM3	0.475	0.088
KIR3DS1	SERPINB5	0.474
KPRP	SERPINB5	0.473	0.1
PKP3	CTSV	0.472	0.204
CSTA	LCN2	0.47	0.244	structurally_consistent (P05089)
JUP	SERPINA12	0.47
S100A7A	DSG1	0.47
CALML3	AZGP1	0.469	0.274
GGCT	GM2A	0.463	0.194
ACP3	ZIC1	0.458
DSG1	PKP3	0.453	0.196
CDSN	S100A7A	0.451
ASAH1	CTSV	0.451	0.162
S100A7	SERPINA12	0.45
ASAH1	CDSN	0.449
ASAH1	DSC1	0.448	0.06
CALML5	SERPINA12	0.444
CDSN	S100A9	0.441
DSP	ZIC1	0.438
ALOX12B	EVPL	0.435	0.074
TYMP	SDR9C7	0.434
KPRP	LCN2	0.432	0.066
TYMP	ARG1	0.43	0.150625
ECM1	TREX2	0.43
DSC1	FCGBP	0.427	0.054
ASAH1	KLK7	0.426
S100A11	SDR9C7	0.425
DSP	SERPINA12	0.419
HRNR	POF1B	0.419	0.082
S100A7	PKP3	0.419	0.254
GGCT	AZGP1	0.419	0.17
GGCT	FLG2	0.417	0.156
S100A11	ACP3	0.416	0.22
EVPL	SDR9C7	0.415
KIR3DS1	TGM3	0.415
KPRP	EVPL	0.414	0.076
ASAH1	GM2A	0.414	0.192
JUP	SERPINB5	0.411	0.314
S100A11	TGM3	0.41	0.126
GGCT	CSTA	0.409	0.098
HAL	PKP3	0.408
ALOX12B	TREX2	0.407
TREX2	FLG2	0.405
JUP	CPA4	0.399	0.342
SERPINB12	GGCT	0.397	0.132
ASAH1	FLG2	0.396	0.074
S100A16	DSG1	0.392	0.072
ASAH1	POF1B	0.391	0.036
ECM1	S100A7A	0.388
CDSN	FCGBP	0.388
JUP	SDR9C7	0.387
ECM1	FCGBP	0.381
FLG2	FCGBP	0.38
GGCT	DSC1	0.38	0.064
KIR3DS1	CSTA	0.379
S100A14	GGCT	0.378	0.034
SERPINB12	S100A7A	0.377
GGCT	FLG	0.376	0.114
EVPL	CASP14	0.376	0.096
PPL	CASP14	0.373	0.24
S100A11	SERPINB5	0.372	0.256
ECM1	PPL	0.371	0.168
CDSN	ACP3	0.368
KLK7	HRNR	0.358
S100A16	DSC1	0.357	0.062
SDR9C7	PKP3	0.352
TGM3	ZIC1	0.349
FLG	PKP3	0.345	0.348
CPA4	PPL	0.343	0.19
CPA4	S100A7A	0.339
ASAH1	GGCT	0.338	0.05
HRNR	SDR9C7	0.336
CALML5	SDR9C7	0.336
ASAH1	S100A7	0.334	0.078
GGCT	S100A16	0.332	0.01
TYMP	CPA4	0.327	0.072
GGCT	SBSN	0.326
CSTA	PKP3	0.324	0.348
CALML3	SDR9C7	0.32
S100A9	PKP3	0.319	0.116
KIR3DS1	PPL	0.319
JUP	S100A7A	0.313
PPL	CSTA	0.308	0.172
SERPINA12	SERPINB3	0.304
AZGP1	PKP3	0.304	0.082
EVPL	AZGP1	0.303	0.086
GGCT	S100A11	0.302	0.02
GGCT	CPA4	0.297	0.016
HRNR	S100A16	0.291	0.088
S100A11	S100A7A	0.29
KLK7	GGCT	0.289
ARG1	LCN2	0.288	0.216	structurally_consistent (dimer)
HRNR	PPL	0.285	0.296
KPRP	S100A7A	0.283
KLK7	S100A11	0.279
LCN2	PKP3	0.277	0.194
CPA4	KIR3DS1	0.273
GGCT	SERPINA12	0.271
S100A8	PKP3	0.27	0.074
S100A14	S100A7A	0.268
S100A14	S100A11	0.267	0.082
KPRP	GGCT	0.266	0.08
S100A8	SERPINA12	0.265
S100A11	CSTA	0.264	0.122
CDSN	LCN2	0.264
ALOX12B	KIR3DS1	0.263
GGCT	HRNR	0.26	0.054
ARG1	GGCT	0.26	0.164
HRNR	PKP3	0.259	0.334
ASAH1	ZIC1	0.258
S100A7A	SERPINA12	0.256
GGCT	PPL	0.244	0.036
ASAH1	SERPINA12	0.243
KIR3DS1	DSG1	0.24
ECM1	EVPL	0.238	0.074
GGCT	PKP1	0.236	0.016
GGCT	ACP3	0.235	0.07
S100A11	SBSN	0.234
S100A11	PKP1	0.232	0.116
S100A11	AZGP1	0.232	0.066
ASAH1	ARG1	0.229	0.166
GGCT	CALML5	0.229	0.174
GGCT	S100A7	0.225	0.126
DSC1	LCN2	0.224	0.124
GGCT	S100A8	0.221	0.062
JUP	PPL	0.218	0.204285714286
ECM1	S100A11	0.217	0.06
GGCT	S100A7A	0.217
KPRP	S100A11	0.216	0.094
CDSN	PPL	0.208
SERPINA12	LCN2	0.208
ECM1	GGCT	0.208	0.062
TYMP	FLG	0.199	0.088
ASAH1	FLG	0.194	0.062
POF1B	ZIC1	0.194
GGCT	SDR9C7	0.193
S100A11	CTSV	0.188	0.118
GGCT	PKP3	0.187	0.078
S100A7A	DSC1	0.186
KIR3DS1	SERPINA12	0.186
SERPINB12	LCN2	0.186	0.072
ASAH1	SERPINB12	0.183	0.04
GGCT	DSG1	0.178	0.068
GGCT	CTSV	0.178	0.072
DSG1	LCN2	0.173	0.064
ASAH1	DSG1	0.172	0.074
GGCT	SERPINB5	0.171	0.128
SERPINB12	S100A11	0.17	0.088
ASAH1	HAL	0.168
HRNR	SBSN	0.164
EVPL	FLG2	0.164	0.056
ECM1	SERPINB5	0.163	0.06
FLG2	PKP3	0.162	0.302
SERPINB12	EVPL	0.161	0.136
S100A11	FLG	0.161	0.036
TYMP	ECM1	0.161	0.09
ASAH1	SERPINB3	0.161	0.092
HRNR	TGM3	0.159	0.42
ARG1	PPL	0.158	0.28
SERPINA12	PKP3	0.154
SERPINB12	SERPINB5	0.15	0.092
ARG1	EVPL	0.149	0.14
CDSN	EVPL	0.149
TREX2	HRNR	0.148		mutually_exclusive (P31151)
ASAH1	S100A9	0.147	0.03
TYMP	GGCT	0.147	0.074
CALML3	SERPINA12	0.146
PKP3	GSDMA	0.146	0.202357142857
TYMP	HRNR	0.143	0.088
EVPL	SERPINA12	0.143
HRNR	FLG	0.137	0.424
TGM1	HRNR	0.132	0.378
ASAH1	LCN2	0.128	0.094
CALML3	ZIC1	0.128
EVPL	DSC1	0.125	0.134
GGCT	S100A9	0.124	0.07
CDSN	GGCT	0.118
HAL	HRNR	0.112
HRNR	SERPINB5	0.11	0.197333333333
PPL	FLG2	0.109	0.292
S100A7A	FLG2	0.108
ASAH1	PKP1	0.108	0.07
KIR3DS1	SBSN	0.107
ASAH1	S100A8	0.104	0.032
JUP	S100A11	0.098	0.234
TGM1	KIR3DS1	0.095
HRNR	CALML3	0.095	0.13
S100A11	DSP	0.095	0.138
HRNR	EVPL	0.093	0.094
CDSN	S100A11	0.09
S100A11	DSC1	0.088	0.094
S100A11	DSG1	0.088	0.106
LCN2	ZIC1	0.086
NCCRP1	KIR3DS1	0.086
ECM1	PKP3	0.084	0.14
PKP1	ZIC1	0.083
PPL	SERPINA12	0.083
HRNR	AZGP1	0.081	0.202
GGCT	LCN2	0.081	0.064
S100A11	FLG2	0.08	0.17
SERPINA12	FCGBP	0.08
S100A11	SERPINA12	0.077
ASAH1	FCGBP	0.077	0.02
SERPINB12	KIR3DS1	0.072
ASAH1	S100A11	0.07	0.052
SERPINB5	FLG2	0.064	0.082
ASAH1	EVPL	0.063	0.07
ASAH1	CALML5	0.062	0.1
CPA4	HRNR	0.061	0.126
HRNR	GSDMA	0.06	0.264
HRNR	GM2A	0.059	0.032
FLG2	LCN2	0.058	0.056
HRNR	S100A7	0.057	0.306	structurally_consistent (dimer)
HRNR	CASP14	0.056	0.468
ALOX12B	HRNR	0.055	0.152
ASAH1	CALML3	0.051	0.184
ARG1	KIR3DS1	0.049
ASAH1	TREX2	0.045
TYMP	ASAH1	0.045	0.04
GGCT	DSP	0.044	0.138
DSG1	ZIC1	0.043
GGCT	CALML3	0.042	0.186
ASAH1	S100A7A	0.041
KIR3DS1	FLG2	0.041
GGCT	KIR3DS1	0.039
HRNR	SERPINB3	0.039	0.242
HRNR	S100A9	0.036	0.148	mutually_exclusive (P31151)
HRNR	SERPINA12	0.033
HRNR	CALML5	0.032	0.194
ASAH1	JUP	0.03	0.062
HRNR	S100A8	0.028	0.0760869565217	mutually_exclusive (P31151)
ASAH1	PPL	0.026	0.056
JUP	KIR3DS1	0.025
HRNR	S100A11	0.021	0.23
ASAH1	DSP	0.019	0.048
ASAH1	HRNR	0.018	0.06
HRNR	KIR3DS1	0.016
JUP	GGCT	0.012	0.204
ASAH1	PKP3	0.012	0.066
ASAH1	SERPINB5	0.011	0.044
HRNR	LCN2	0.009	0.102
DSC1	ZIC1	0.009
HRNR	CTSV	0.008	0.16
HRNR	FCGBP	0.007
KIR3DS1	PKP1	0.007
HRNR	ACP3	0.004	0.126
HRNR	S100A7A	0.001

Related Complexes

Genename	Complexes
CASP14	huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1 huMAP3_14573.1
GGCT	huMAP3_01434.1 huMAP3_02738.1 huMAP3_04424.1 huMAP3_04732.1 huMAP3_05804.1 huMAP3_06323.1 huMAP3_07255.1 huMAP3_07646.1 huMAP3_08429.1 huMAP3_09125.1 huMAP3_09833.1 huMAP3_09929.1 huMAP3_10678.1
ARG1	huMAP3_00465.1 huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1 huMAP3_13873.1
TREX2	huMAP3_01434.1 huMAP3_03864.1 huMAP3_04424.1 huMAP3_05804.1 huMAP3_06323.1 huMAP3_07255.1 huMAP3_07761.1 huMAP3_08429.1 huMAP3_09125.1 huMAP3_09833.1 huMAP3_09929.1 huMAP3_10678.1 huMAP3_13525.1
KPRP	huMAP3_00338.1 huMAP3_00954.1 huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1 huMAP3_10280.1 huMAP3_10904.1 huMAP3_11732.1
HAL	huMAP3_00465.1 huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1
S100A8	huMAP3_03564.1 huMAP3_03764.1 huMAP3_07287.1 huMAP3_08811.1 huMAP3_09125.1 huMAP3_09929.1
GM2A	huMAP3_05900.1 huMAP3_07865.1 huMAP3_09125.1 huMAP3_09929.1
EVPL	huMAP3_04732.1 huMAP3_06323.1 huMAP3_07255.1 huMAP3_07646.1 huMAP3_09125.1 huMAP3_09833.1 huMAP3_09929.1 huMAP3_10678.1
SBSN	huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1 huMAP3_13462.1
TGM1	huMAP3_00918.1 huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1
AZGP1	huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1
ASAH1	huMAP3_00465.1 huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1 huMAP3_11582.1 huMAP3_11995.1 huMAP3_13592.1 huMAP3_15172.1
TYMP	huMAP3_00406.1 huMAP3_05900.1 huMAP3_06323.1 huMAP3_07646.1 huMAP3_08527.1 huMAP3_09125.1 huMAP3_09833.1 huMAP3_09929.1 huMAP3_10678.1
S100A9	huMAP3_03843.1 huMAP3_05900.1 huMAP3_07865.1 huMAP3_09125.1 huMAP3_09929.1 huMAP3_13594.1
S100A7A	huMAP3_03764.1 huMAP3_03864.1 huMAP3_07287.1 huMAP3_07646.1 huMAP3_08811.1 huMAP3_09125.1 huMAP3_09434.1 huMAP3_09929.1 huMAP3_10678.1 huMAP3_13525.1
TGM3	huMAP3_06003.1 huMAP3_08560.1 huMAP3_09125.1 huMAP3_09929.1
NCCRP1	huMAP3_00682.1 huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1
PKP1	huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1
ECM1	huMAP3_00465.1 huMAP3_01971.1 huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1 huMAP3_11175.1
FLG2	huMAP3_04874.1 huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1 huMAP3_14076.1
GSDMA	huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1
FLG	huMAP3_06003.1 huMAP3_08560.1 huMAP3_09125.1 huMAP3_09929.1
KIR3DS1	huMAP3_03348.1 huMAP3_03564.1 huMAP3_03764.1 huMAP3_07287.1 huMAP3_08811.1 huMAP3_09125.1 huMAP3_09929.1 huMAP3_10813.1 huMAP3_11096.1
DSP	huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1
S100A7	huMAP3_03843.1 huMAP3_09125.1 huMAP3_09929.1
KLK7	huMAP3_00954.1 huMAP3_03982.1 huMAP3_07460.1 huMAP3_08731.1 huMAP3_09125.1 huMAP3_09834.1 huMAP3_09929.1 huMAP3_10280.1
DSG1	huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1
FCGBP	huMAP3_06323.1 huMAP3_07255.1 huMAP3_07761.1 huMAP3_09125.1 huMAP3_09833.1 huMAP3_09929.1 huMAP3_10678.1
DSC1	huMAP3_04874.1 huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1
S100A14	huMAP3_00918.1 huMAP3_03910.1 huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1
ACP3	huMAP3_05900.1 huMAP3_07972.1 huMAP3_09125.1 huMAP3_09929.1
CPA4	huMAP3_01757.1 huMAP3_09125.1 huMAP3_09929.1 huMAP3_10269.1
HRNR	huMAP3_01769.1 huMAP3_04874.1 huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1 huMAP3_11079.1 huMAP3_11964.1
ZIC1	huMAP3_07865.1 huMAP3_09125.1 huMAP3_09929.1 huMAP3_12091.1 huMAP3_13592.1
CTSV	huMAP3_07865.1 huMAP3_09125.1 huMAP3_09929.1
SDR9C7	huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1 huMAP3_12091.1 huMAP3_13592.1
SERPINB12	huMAP3_00488.1 huMAP3_01769.1 huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1 huMAP3_11079.1
CALML3	huMAP3_03608.1 huMAP3_06046.1 huMAP3_07972.1 huMAP3_09125.1 huMAP3_09929.1 huMAP3_12531.1
PPL	huMAP3_03608.1 huMAP3_06046.1 huMAP3_06323.1 huMAP3_07646.1 huMAP3_07972.1 huMAP3_09125.1 huMAP3_09833.1 huMAP3_09929.1 huMAP3_10678.1
JUP	huMAP3_00682.1 huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1
POF1B	huMAP3_06046.1 huMAP3_07972.1 huMAP3_09125.1 huMAP3_09929.1
S100A16	huMAP3_03910.1 huMAP3_07972.1 huMAP3_09125.1 huMAP3_09929.1
SERPINB3	huMAP3_05900.1 huMAP3_07972.1 huMAP3_09125.1 huMAP3_09929.1
S100A11	huMAP3_03207.1 huMAP3_03764.1 huMAP3_04011.1 huMAP3_05804.1 huMAP3_07287.1 huMAP3_08429.1 huMAP3_08527.1 huMAP3_09125.1 huMAP3_09929.1 huMAP3_11007.1 huMAP3_12014.1
CALML5	huMAP3_03764.1 huMAP3_07287.1 huMAP3_08811.1 huMAP3_09125.1 huMAP3_09929.1
LCN2	huMAP3_05900.1 huMAP3_06637.1 huMAP3_08328.1 huMAP3_08527.1 huMAP3_09125.1 huMAP3_09434.1 huMAP3_09929.1 huMAP3_10678.1 huMAP3_12771.1
CSTA	huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1 huMAP3_12619.1
CDSN	huMAP3_00488.1 huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1
ALOX12B	huMAP3_00465.1 huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1
SERPINB5	huMAP3_03608.1 huMAP3_03864.1 huMAP3_06323.1 huMAP3_07255.1 huMAP3_07761.1 huMAP3_09125.1 huMAP3_09833.1 huMAP3_09929.1 huMAP3_10678.1 huMAP3_11636.1
PKP3	huMAP3_06046.1 huMAP3_07972.1 huMAP3_09125.1 huMAP3_09929.1
SERPINA12	huMAP3_05845.1 huMAP3_08595.1 huMAP3_09125.1 huMAP3_09929.1 huMAP3_11196.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_09125.1

Complex Portal: CPX-12680