List of Gene Names or Uniprot ACCs (ex. OFD1 PCM1 Q1MSJ5):

Enrichment (ex. cilium):

Protein (ex. Centrosomal protein):

Complex: huMAP3_09129.1

Confidence: Moderate High   ?

Proteins

Genename	Protein Name	Uniprot Annotation Score	Links
ORMDL3	ORM1-like protein 3	5	UniProt   NCBI
SLC2A12	Solute carrier family 2, facilitated glucose transporter member 12 (Glucose transporter type 12) (GLUT-12)	4	UniProt   NCBI
ORMDL2	ORM1-like protein 2 (Adoplin-2)	5	UniProt   NCBI
SLC5A5	Sodium/iodide cotransporter (Na(+)/I(-) cotransporter) (Natrium iodide transporter) (Sodium-iodide symporter) (Na(+)/I(-) symporter) (Solute carrier family 5 member 5)	5	UniProt   NCBI



Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-1660661	0.00573491177379	0.5	ORMDL3 ORMDL2	Sphingolipid de novo biosynthesis
WP:WP2884	0.015715675352	0.5	SLC2A12 SLC5A5	NRF2 pathway
GO:0035339	0.0168521501606	0.5	ORMDL3 ORMDL2	SPOTS complex
GO:0090156	0.0168521501606	0.5	ORMDL3 ORMDL2	intracellular sphingolipid homeostasis
REAC:R-HSA-428157	0.0267695204965	0.5	ORMDL3 ORMDL2	Sphingolipid metabolism
GO:1900060	0.0280843539964	0.5	ORMDL3 ORMDL2	negative regulation of ceramide biosynthetic process
GO:0017059	0.042122686785	0.5	ORMDL3 ORMDL2	serine C-palmitoyltransferase complex
GO:0031211	0.042122686785	0.5	ORMDL3 ORMDL2	endoplasmic reticulum palmitoyltransferase complex
GO:0090155	0.042122686785	0.5	ORMDL3 ORMDL2	negative regulation of sphingolipid biosynthetic process
HPA:0120233	0.0424284218432	0.25	SLC5A5	choroid plexus; ependymal cells[High]
CORUM:6982	0.049938562206	0.25	ORMDL3	ORMDL3-SPTLC1 complex
REAC:R-HSA-5619096	0.0499436884912	0.25	SLC5A5	Defective SLC5A5 causes thyroid dyshormonogenesis 1 (TDH1)



Edges

Protein 1	Protein 2	Score ?	ProteomeHD?	Evidence ?
ORMDL2	ORMDL3	0.988	0.262	bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     gupta_WMM     WMM_only
ORMDL3	SLC2A12	0.98		bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM
ORMDL2	SLC2A12	0.977		bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM
SLC5A5	ORMDL2	0.95		bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM





Related Complexes

Genename	Complexes
ORMDL3	huMAP3_02581.1 huMAP3_08192.1 huMAP3_08330.1 huMAP3_09129.1 huMAP3_09260.1 huMAP3_09967.1 huMAP3_10343.1 huMAP3_11807.1 huMAP3_12795.1 huMAP3_15312.1
SLC2A12	huMAP3_03108.1 huMAP3_08192.1 huMAP3_09129.1 huMAP3_09260.1 huMAP3_09967.1 huMAP3_10343.1 huMAP3_11807.1
ORMDL2	huMAP3_00816.1 huMAP3_02581.1 huMAP3_06154.1 huMAP3_08330.1 huMAP3_09129.1 huMAP3_09260.1 huMAP3_09967.1 huMAP3_10343.1 huMAP3_12356.1 huMAP3_12795.1 huMAP3_12903.1 huMAP3_15199.1 huMAP3_15312.1
SLC5A5	huMAP3_00816.1 huMAP3_08330.1 huMAP3_09129.1 huMAP3_09967.1 huMAP3_10356.1 huMAP3_15199.1 huMAP3_15230.1