hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_09140.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| ENDOG | Endonuclease G, mitochondrial (Endo G) (EC 3.1.30.-) | 5 | UniProt NCBI |
| GRK4 | G protein-coupled receptor kinase 4 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK4) (ITI1) | 5 | UniProt NCBI |
| GRK6 | G protein-coupled receptor kinase 6 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK6) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:05032 | 0.00173372250929 | 0.666666666667 | GRK6 GRK4 | Morphine addiction |
| WP:WP536 | 0.00700579973273 | 0.666666666667 | GRK6 GRK4 | Calcium regulation in cardiac cells |
| KEGG:04062 | 0.00727572841175 | 0.666666666667 | GRK6 GRK4 | Chemokine signaling pathway |
| WP:WP3929 | 0.00817907289077 | 0.666666666667 | GRK6 GRK4 | Chemokine signaling pathway |
| WP:WP289 | 0.00958854810456 | 0.666666666667 | GRK6 GRK4 | Myometrial relaxation and contraction pathways |
| GO:0004703 | 0.0140440992017 | 0.666666666667 | GRK6 GRK4 | G protein-coupled receptor kinase activity |
| KEGG:04144 | 0.0200670831031 | 0.666666666667 | GRK6 GRK4 | Endocytosis |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| GRK4 | GRK6 | 0.992 | 0.24 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| GRK6 | ENDOG | 0.959 | 0.09 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM |
Related Complexes
| Genename | Complexes |
|---|---|
| ENDOG | huMAP3_09140.1 huMAP3_10363.1 huMAP3_13227.1 huMAP3_14723.1 |
| GRK4 | huMAP3_00158.1 huMAP3_09140.1 huMAP3_12831.1 huMAP3_14300.1 |
| GRK6 | huMAP3_00158.1 huMAP3_06673.1 huMAP3_09140.1 huMAP3_12831.1 |