hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_09142.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PAIP1 | Polyadenylate-binding protein-interacting protein 1 (PABP-interacting protein 1) (PAIP-1) (Poly(A)-binding protein-interacting protein 1) | 5 | UniProt NCBI |
| MKRN2 | E3 ubiquitin-protein ligase makorin-2 (EC 2.3.2.27) (RING finger protein 62) (RING-type E3 ubiquitin transferase makorin-2) | 5 | UniProt NCBI |
| LARP4B | La-related protein 4B (La ribonucleoprotein domain family member 4B) (La ribonucleoprotein domain family member 5) (La-related protein 5) | 5 | UniProt NCBI |
| GSPT2 | Eukaryotic peptide chain release factor GTP-binding subunit ERF3B (Eukaryotic peptide chain release factor subunit 3b) (eRF3b) (EC 3.6.5.-) (G1 to S phase transition protein 2 homolog) | 5 | UniProt NCBI |
| PABPC1L | Polyadenylate-binding protein 1-like | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP107 | 0.00687274586933 | 0.4 | GSPT2 PAIP1 | Translation factors |
| KEGG:03015 | 0.0183886697314 | 0.4 | GSPT2 PABPC1L | mRNA surveillance pathway |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| MKRN2 | GSPT2 | 0.983 | 0.168 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| PAIP1 | MKRN2 | 0.982 | 0.232 | youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM |
| PAIP1 | LARP4B | 0.974 | 0.086 | hein_WMM youn () bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| PAIP1 | GSPT2 | 0.961 | 0.246 | youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| MKRN2 | LARP4B | 0.304 | 0.154 | youn () bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| GSPT2 | LARP4B | 0.01 | 0.21 | youn_WMM WMM_only |
Related Complexes