hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_09149.1
Complex Portal: CPX-24762
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| SDE2 | Splicing regulator SDE2 (Replication stress response regulator SDE2) | 5 | UniProt NCBI |
| MAGOHB | Protein mago nashi homolog 2 | 5 | UniProt NCBI |
| RBM8A | RNA-binding protein 8A (Binder of OVCA1-1) (BOV-1) (RNA-binding motif protein 8A) (RNA-binding protein Y14) (Ribonucleoprotein RBM8A) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-72163 | 0.000622120634792 | 1.0 | SDE2 RBM8A MAGOHB | mRNA Splicing - Major Pathway |
| REAC:R-HSA-72172 | 0.000689757414765 | 1.0 | SDE2 RBM8A MAGOHB | mRNA Splicing |
| REAC:R-HSA-72203 | 0.00158225905908 | 1.0 | SDE2 RBM8A MAGOHB | Processing of Capped Intron-Containing Pre-mRNA |
| KEGG:03015 | 0.00311331063035 | 0.666666666667 | MAGOHB RBM8A | mRNA surveillance pathway |
| KEGG:03013 | 0.00383761092368 | 0.666666666667 | MAGOHB RBM8A | Nucleocytoplasmic transport |
| GO:1903503 | 0.00421361424067 | 0.666666666667 | MAGOHB RBM8A | ATPase inhibitor complex |
| GO:1990501 | 0.00421361424067 | 0.666666666667 | MAGOHB RBM8A | exon-exon junction subcomplex mago-y14 |
| KEGG:03040 | 0.00588292524774 | 0.666666666667 | MAGOHB RBM8A | Spliceosome |
| REAC:R-HSA-72187 | 0.0101009261622 | 0.666666666667 | MAGOHB RBM8A | mRNA 3'-end processing |
| REAC:R-HSA-73856 | 0.0132793882188 | 0.666666666667 | MAGOHB RBM8A | RNA Polymerase II Transcription Termination |
| REAC:R-HSA-159236 | 0.0164154902665 | 0.666666666667 | MAGOHB RBM8A | Transport of Mature mRNA derived from an Intron-Containing Transcript |
| REAC:R-HSA-72202 | 0.0209338694285 | 0.666666666667 | MAGOHB RBM8A | Transport of Mature Transcript to Cytoplasm |
| REAC:R-HSA-8953854 | 0.0247774527734 | 1.0 | SDE2 RBM8A MAGOHB | Metabolism of RNA |
| REAC:R-HSA-975957 | 0.0436932800731 | 0.666666666667 | MAGOHB RBM8A | Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
| REAC:R-HSA-927802 | 0.0436932800731 | 0.666666666667 | MAGOHB RBM8A | Nonsense-Mediated Decay (NMD) |
| CORUM:763 | 0.0499402709677 | 0.333333333333 | RBM8A | Y14-Magoh complex |
| CORUM:773 | 0.0499402709677 | 0.333333333333 | RBM8A | Y14-Magoh complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| RBM8A | SDE2 | 0.991 | 0.202 | hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein () gupta_WMM | |
| RBM8A | MAGOHB | 0.983 | 0.946 |
mutually_exclusive (Q96J01)
structurally_consistent (dimer) |
hein_WMM bioplex3_WMM hein () gupta_WMM |
| SDE2 | MAGOHB | 0.179 | 0.224 | hein_WMM bioplex3_WMM WMM_only |
Related Complexes