hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_09152.1
Confidence: Moderate High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
MELK | Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2) | 5 | UniProt   NCBI |
IGF1R | Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain] | 5 | UniProt   NCBI |
HPSE | Heparanase (EC 3.2.1.166) (Endo-glucoronidase) (Heparanase-1) (Hpa1) [Cleaved into: Heparanase 8 kDa subunit; Heparanase 50 kDa subunit] | 5 | UniProt   NCBI |
FIBIN | Fin bud initiation factor homolog | 4 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  KEGG:05205 | 0.0406374666322 | 0.5 | HPSE IGF1R | Proteoglycans in cancer |
  CORUM:6251 | 0.049938562206 | 0.25 | IGF1R | Shc-ERalpha-IGF-1R complex |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 FIBIN |  MELK | 0.99 |            | bioplex3_WMM     bioplex3_HCT116     WMM_only     |
 IGF1R |  FIBIN | 0.976 |            | bioplex3_WMM     bioplex3_HCT116     WMM_only     |
 IGF1R |  HPSE | 0.965 | 0.082           | bioplex3_HEK293     bioplex ()     bioplex_WMM     bioplex3_WMM     |
 HPSE |  FIBIN | 0.952 |            | bioplex3_WMM     bioplex3_HCT116     WMM_only     |
 HPSE |  MELK | 0.795 | 0.094           | bioplex_WMM     bioplex3_WMM     WMM_only     |
 IGF1R |  MELK | 0.081 | 0.098           | bioplex_WMM     bioplex3_WMM     WMM_only     |
Related Complexes
Genename | Complexes |
---|---|
MELK | huMAP3_09152.1 huMAP3_09949.1 huMAP3_15307.1 |
IGF1R | huMAP3_02023.1 huMAP3_03755.1 huMAP3_08471.1 huMAP3_08814.1 huMAP3_09152.1 huMAP3_09703.1 huMAP3_11006.1 |
HPSE | huMAP3_03755.1 huMAP3_09152.1 |
FIBIN | huMAP3_03755.1 huMAP3_09152.1 |