hu.MAP 3.0: Complex View

Genename	Protein Name	Uniprot Annotation Score	Links
MELK	Maternal embryonic leucine zipper kinase (hMELK) (EC 2.7.11.1) (Protein kinase Eg3) (pEg3 kinase) (Protein kinase PK38) (hPK38) (Tyrosine-protein kinase MELK) (EC 2.7.10.2)	5	UniProt NCBI
IGF1R	Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]	5	UniProt NCBI
HPSE	Heparanase (EC 3.2.1.166) (Endo-glucoronidase) (Heparanase-1) (Hpa1) [Cleaved into: Heparanase 8 kDa subunit; Heparanase 50 kDa subunit]	5	UniProt NCBI
FIBIN	Fin bud initiation factor homolog	4	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
KEGG:05205	0.0406374666322	0.5	HPSE IGF1R	Proteoglycans in cancer
CORUM:6251	0.049938562206	0.25	IGF1R	Shc-ERalpha-IGF-1R complex

Protein 1	Protein 2	Score	ProteomeHD	Evidence
FIBIN	MELK	0.99		bioplex3_WMM bioplex3_HCT116 WMM_only
IGF1R	FIBIN	0.976		bioplex3_WMM bioplex3_HCT116 WMM_only
IGF1R	HPSE	0.965	0.082	bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
HPSE	FIBIN	0.952		bioplex3_WMM bioplex3_HCT116 WMM_only
HPSE	MELK	0.795	0.094	bioplex_WMM bioplex3_WMM WMM_only
IGF1R	MELK	0.081	0.098	bioplex_WMM bioplex3_WMM WMM_only

Genename	Complexes
MELK	huMAP3_09152.1 huMAP3_09949.1 huMAP3_15307.1
IGF1R	huMAP3_02023.1 huMAP3_03755.1 huMAP3_08471.1 huMAP3_08814.1 huMAP3_09152.1 huMAP3_09703.1 huMAP3_11006.1
HPSE	huMAP3_03755.1 huMAP3_09152.1
FIBIN	huMAP3_03755.1 huMAP3_09152.1