hu.MAP 3.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: huMAP3_09166.1
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| NDRG1 | Protein NDRG1 (Differentiation-related gene 1 protein) (DRG-1) (N-myc downstream-regulated gene 1 protein) (Nickel-specific induction protein Cap43) (Reducing agents and tunicamycin-responsive protein) (RTP) (Rit42) | 5 | UniProt NCBI |
| TLN1 | Talin-1 | 5 | UniProt NCBI |
| CDV3 | Protein CDV3 homolog | 3 | UniProt NCBI |
| NHERF1 | Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1) | 5 | UniProt NCBI |
| UBE2T | Ubiquitin-conjugating enzyme E2 T (EC 2.3.2.23) (Cell proliferation-inducing gene 50 protein) (E2 ubiquitin-conjugating enzyme T) (Ubiquitin carrier protein T) (Ubiquitin-protein ligase T) | 5 | UniProt NCBI |
| VAT1 | Synaptic vesicle membrane protein VAT-1 homolog (EC 1.-.-.-) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:682 | 0.0499436884912 | 0.166666666667 | NHERF1 | C-CFTR-NHERF-ezrin complex |
| CORUM:687 | 0.0499436884912 | 0.166666666667 | NHERF1 | CFTR-NHERF-beta(2)AR signaling complex |
| CORUM:2378 | 0.0499436884912 | 0.166666666667 | TLN1 | ITGA2b-ITGB3-TLN1 complex |
| CORUM:6791 | 0.0499436884912 | 0.166666666667 | NHERF1 | NHERF1-NPT2A-EZR complex |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
|---|---|---|---|---|
| UBE2T | TLN1 | 0.993 | 0.102 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| UBE2T | NHERF1 | 0.99 | 0.028 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| UBE2T | CDV3 | 0.974 | 0.048 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| VAT1 | UBE2T | 0.965 | 0.02 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only |
| UBE2T | NDRG1 | 0.962 | 0.032 | bioplex3_WMM bioplex3_HCT116 WMM_only |
| CDV3 | NHERF1 | 0.891 | 0.064 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| CDV3 | NDRG1 | 0.653 | 0.076 | bioplex3_WMM gupta_WMM WMM_only |
| VAT1 | NHERF1 | 0.457 | 0.076 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only treiber_WMM |
| TLN1 | NHERF1 | 0.389 | 0.206 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM fraction |
| CDV3 | TLN1 | 0.362 | 0.146 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only |
| NDRG1 | TLN1 | 0.342 | 0.336 | bioplex3_WMM gupta_WMM fraction |
| VAT1 | CDV3 | 0.235 | 0.096 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| NDRG1 | NHERF1 | 0.028 | 0.09 | bioplex3_WMM gupta_WMM fraction |
| VAT1 | NDRG1 | 0.023 | 0.19 | bioplex_WMM bioplex3_WMM gupta_WMM WMM_only |
| VAT1 | TLN1 | 0.016 | 0.345 | bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only boldt_WMM treiber_WMM |
Related Complexes