hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09186.1
Complex Portal: CPX-22542
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| PAIP1 | Polyadenylate-binding protein-interacting protein 1 (PABP-interacting protein 1) (PAIP-1) (Poly(A)-binding protein-interacting protein 1) | 5 | UniProt NCBI |
| APOBEC3F | DNA dC->dU-editing enzyme APOBEC-3F (EC 3.5.4.38) (Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F) (A3F) | 5 | UniProt NCBI |
| MKRN3 | Probable E3 ubiquitin-protein ligase makorin-3 (EC 2.3.2.27) (RING finger protein 63) (RING-type E3 ubiquitin transferase makorin-3) (Zinc finger protein 127) | 5 | UniProt NCBI |
| MKRN2 | E3 ubiquitin-protein ligase makorin-2 (EC 2.3.2.27) (RING finger protein 62) (RING-type E3 ubiquitin transferase makorin-2) | 5 | UniProt NCBI |
| PUM2 | Pumilio homolog 2 (Pumilio-2) | 5 | UniProt NCBI |
| LARP4B | La-related protein 4B (La ribonucleoprotein domain family member 4B) (La ribonucleoprotein domain family member 5) (La-related protein 5) | 5 | UniProt NCBI |
| PAIP2 | Polyadenylate-binding protein-interacting protein 2 (PABP-interacting protein 2) (PAIP-2) (Poly(A)-binding protein-interacting protein 2) | 5 | UniProt NCBI |
| MKRN1 | E3 ubiquitin-protein ligase makorin-1 (EC 2.3.2.27) (RING finger protein 61) (RING-type E3 ubiquitin transferase makorin-1) | 5 | UniProt NCBI |
| GSPT2 | Eukaryotic peptide chain release factor GTP-binding subunit ERF3B (Eukaryotic peptide chain release factor subunit 3b) (eRF3b) (EC 3.6.5.-) (G1 to S phase transition protein 2 homolog) | 5 | UniProt NCBI |
| PABPC1L | Polyadenylate-binding protein 1-like | 3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0003723 | 0.00030331647863 | 0.9 | GSPT2 LARP4B PABPC1L PUM2 PAIP1 MKRN2 MKRN3 APOBEC3F MKRN1 | RNA binding |
| WP:WP107 | 0.0479442074014 | 0.2 | GSPT2 PAIP1 | Translation factors |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| PAIP1 | PAIP2 | 0.999 | 0.08 | youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| GSPT2 | MKRN3 | 0.994 | 0.064 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PUM2 | PAIP1 | 0.994 | bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | ||
| PAIP1 | MKRN1 | 0.99 | 0.0713333333333 | youn () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| MKRN1 | GSPT2 | 0.987 | 0.09 | bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| PUM2 | PAIP2 | 0.986 | youn () bioplex_WMM bioplex3_WMM youn_WMM WMM_only | ||
| PUM2 | LARP4B | 0.984 | youn () bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 treiber_WMM WMM_only | ||
| LARP4B | MKRN3 | 0.984 | 0.052 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MKRN2 | GSPT2 | 0.983 | 0.168 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 | |
| PAIP1 | MKRN2 | 0.982 | 0.232 | youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM | |
| PAIP1 | MKRN3 | 0.978 | 0.07 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PUM2 | GSPT2 | 0.974 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| PAIP1 | LARP4B | 0.974 | 0.086 |
mutually_exclusive (P0CB38)
|
hein_WMM youn () bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 gupta_WMM WMM_only |
| MKRN2 | PAIP2 | 0.973 | 0.128 | youn () bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| MKRN1 | LARP4B | 0.966 | 0.084 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| APOBEC3F | LARP4B | 0.961 | 0.084 | bioplex3_HEK293 bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| PAIP1 | GSPT2 | 0.961 | 0.246 |
mutually_exclusive (P0CB38)
|
youn () bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 |
| PAIP1 | APOBEC3F | 0.959 | 0.1 | bioplex_WMM bioplex3_WMM bioplex3_HCT116 WMM_only | |
| APOBEC3F | GSPT2 | 0.951 | 0.058 | bioplex3_WMM bioplex3_HCT116 WMM_only | |
| MKRN2 | MKRN1 | 0.944 | 0.106 | youn () bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| GSPT2 | PAIP2 | 0.915 | 0.17 | bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| LARP4B | PAIP2 | 0.882 | 0.112 | youn () bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM bioplex3_HCT116 WMM_only | |
| APOBEC3F | MKRN1 | 0.882 | 0.108 | bioplex_WMM bioplex3_WMM WMM_only | |
| MKRN1 | PAIP2 | 0.831 | 0.128 | youn () bioplex_WMM bioplex3_WMM youn_WMM WMM_only | |
| PUM2 | MKRN3 | 0.827 | bioplex3_WMM WMM_only | ||
| APOBEC3F | MKRN2 | 0.825 | 0.0941 | bioplex_WMM bioplex3_WMM WMM_only | |
| APOBEC3F | MKRN3 | 0.78 | 0.106 | bioplex3_WMM WMM_only | |
| MKRN1 | MKRN3 | 0.736 | 0.1 | bioplex3_WMM WMM_only | |
| PUM2 | MKRN1 | 0.718 | bioplex3_WMM youn_WMM WMM_only | ||
| PUM2 | APOBEC3F | 0.701 | bioplex_WMM bioplex3_WMM WMM_only | ||
| PAIP2 | MKRN3 | 0.689 | 0.106 | bioplex3_WMM WMM_only | |
| APOBEC3F | PAIP2 | 0.62 | 0.142 | bioplex_WMM bioplex3_WMM WMM_only | |
| MKRN2 | MKRN3 | 0.561 | 0.134 | bioplex3_WMM WMM_only | |
| PUM2 | MKRN2 | 0.45 | youn () bioplex_WMM bioplex3_WMM youn_WMM WMM_only | ||
| MKRN2 | LARP4B | 0.304 | 0.154 | youn () bioplex3_HEK293 bioplex_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only | |
| GSPT2 | LARP4B | 0.01 | 0.21 |
mutually_exclusive (P0CB38)
|
youn_WMM WMM_only |
Related Complexes