hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_09230.1

Confidence: Moderate High

Genename	Protein Name	Uniprot Annotation Score	Links
INTS11	Integrator complex subunit 11 (Int11) (EC 3.1.27.-) (Cleavage and polyadenylation-specific factor 3-like protein) (CPSF3-like protein) (Protein related to CPSF subunits of 68 kDa) (RC-68)	5	UniProt NCBI
INTS6	Integrator complex subunit 6 (Int6) (DBI-1) (Protein DDX26) (Protein deleted in cancer 1) (DICE1)	5	UniProt NCBI
INTS3	Integrator complex subunit 3 (Int3) (SOSS complex subunit A) (Sensor of single-strand DNA complex subunit A) (SOSS-A) (Sensor of ssDNA subunit A)	5	UniProt NCBI
INTS9	Integrator complex subunit 9 (Int9) (Protein related to CPSF subunits of 74 kDa) (RC-74)	5	UniProt NCBI
INTS4	Integrator complex subunit 4 (Int4)	5	UniProt NCBI
INTS2	Integrator complex subunit 2 (Int2)	5	UniProt NCBI
FOXC1	Forkhead box protein C1 (Forkhead-related protein FKHL7) (Forkhead-related transcription factor 3) (FREAC-3)	5	UniProt NCBI
INTS1	Integrator complex subunit 1 (Int1)	5	UniProt NCBI
INTS12	Integrator complex subunit 12 (Int12) (PHD finger protein 22)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
CORUM:1153	7.01606204639e-24	0.888888888889	INTS11 INTS12 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	Integrator complex
CORUM:1155	1.8240650973e-23	0.888888888889	INTS11 INTS12 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	Integrator-RNAPII complex
GO:0032039	6.59632782e-19	0.888888888889	INTS11 INTS12 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	integrator complex
GO:0016180	1.36287546108e-17	0.888888888889	INTS11 INTS12 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	snRNA processing
REAC:R-HSA-6807505	4.9346453542e-16	0.888888888889	INTS11 INTS12 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	RNA polymerase II transcribes snRNA genes
GO:0016073	6.55448800864e-15	0.888888888889	INTS11 INTS12 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	snRNA metabolic process
GO:0034243	2.03894638905e-13	0.888888888889	INTS11 INTS12 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	regulation of transcription elongation by RNA polymerase II
GO:0032784	1.05591163261e-12	0.888888888889	INTS11 INTS12 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	regulation of DNA-templated transcription elongation
CORUM:1154	1.45638287324e-12	0.555555555556	INTS9 INTS4 INTS11 INTS2 INTS6	DSS1 complex
GO:0006368	1.48685611113e-12	0.888888888889	INTS11 INTS12 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	transcription elongation by RNA polymerase II
GO:0006354	5.51175315137e-12	0.888888888889	INTS11 INTS12 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	DNA-templated transcription elongation
GO:0034472	2.30028568441e-08	0.555555555556	INTS1 INTS12 INTS6 INTS2 INTS9	snRNA 3'-end processing
GO:0034470	4.50875044987e-08	0.888888888889	INTS11 INTS12 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	ncRNA processing
GO:0034660	9.68282610571e-07	0.888888888889	INTS11 INTS12 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	ncRNA metabolic process
REAC:R-HSA-73857	2.73537046558e-06	0.888888888889	INTS11 INTS12 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	RNA Polymerase II Transcription
REAC:R-HSA-74160	7.41346360783e-06	0.888888888889	INTS11 INTS12 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	Gene expression (Transcription)
GO:0006396	2.38546830257e-05	0.888888888889	INTS11 INTS12 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	RNA processing
GO:0031123	3.43989524199e-05	0.555555555556	INTS1 INTS12 INTS6 INTS2 INTS9	RNA 3'-end processing
GO:0006366	0.000341817047822	1.0	INTS11 INTS12 FOXC1 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	transcription by RNA polymerase II
GO:0140513	0.000441206708996	0.888888888889	INTS11 INTS12 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	nuclear protein-containing complex
WP:WP5345	0.000723743379875	0.333333333333	INTS4 INTS11 INTS9	1p36 copy number variation syndrome
GO:0006355	0.00303795876717	1.0	INTS11 INTS12 FOXC1 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	regulation of DNA-templated transcription
GO:2001141	0.00320804197401	1.0	INTS11 INTS12 FOXC1 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	regulation of RNA biosynthetic process
GO:0006351	0.00465537895398	1.0	INTS11 INTS12 FOXC1 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	DNA-templated transcription
GO:0032774	0.00512577137556	1.0	INTS11 INTS12 FOXC1 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	RNA biosynthetic process
GO:0051252	0.00831592797017	1.0	INTS11 INTS12 FOXC1 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	regulation of RNA metabolic process
GO:0034654	0.0158700258372	1.0	INTS11 INTS12 FOXC1 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	nucleobase-containing compound biosynthetic process
GO:0018130	0.0187008801665	1.0	INTS11 INTS12 FOXC1 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	heterocycle biosynthetic process
GO:0019438	0.0188805671311	1.0	INTS11 INTS12 FOXC1 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	aromatic compound biosynthetic process
GO:0019219	0.0189408029	1.0	INTS11 INTS12 FOXC1 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	regulation of nucleobase-containing compound metabolic process
GO:1901362	0.0245018387601	1.0	INTS11 INTS12 FOXC1 INTS1 INTS4 INTS9 INTS3 INTS6 INTS2	organic cyclic compound biosynthetic process

Edges

Protein 1	Protein 2	Score	ProteomeHD	Evidence
INTS9	INTS11	1.0	0.91	hein_WMM bioplex3_HEK293 bioplex3_WMM Malo bioplex3_HCT116 fraction
INTS9	INTS4	1.0	0.414	hein_WMM bioplex3_HEK293 bioplex3_WMM youn_WMM hein () Malo bioplex3_HCT116 gupta_WMM fraction
INTS1	INTS12	1.0	0.49	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM youn_WMM Malo fraction
INTS12	INTS4	1.0	0.614	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM hein ()
INTS11	INTS4	0.998	0.494	hein_WMM bioplex_WMM bioplex3_WMM hein () Malo fraction
INTS3	INTS1	0.996	0.732	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM Malo fraction
INTS1	INTS2	0.996	0.418	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM Malo fraction
INTS4	INTS2	0.994	0.492	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only
INTS6	INTS4	0.993	0.886	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM hein ()
INTS6	INTS11	0.99	0.56	hein_WMM bioplex_WMM bioplex3_WMM WMM_only
INTS6	INTS9	0.986	0.48	hein_WMM bioplex3_WMM WMM_only
FOXC1	INTS1	0.985	0.088	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only
INTS3	INTS11	0.982	0.298	hein_WMM bioplex_WMM bioplex3_WMM WMM_only
INTS1	INTS4	0.981	0.774	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only
INTS3	INTS12	0.98	0.392	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only
INTS12	INTS2	0.971	0.258	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only
INTS6	INTS3	0.971	0.308	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
INTS3	INTS4	0.967	0.612	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only
FOXC1	INTS6	0.965	0.1	hein_WMM bioplex_WMM bioplex3_WMM WMM_only
FOXC1	INTS12	0.962	0.148	hein_WMM bioplex_WMM bioplex3_WMM youn_WMM WMM_only
INTS3	INTS2	0.955	0.296	hein_WMM bioplex_WMM bioplex3_WMM WMM_only
INTS6	INTS1	0.955	0.728	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
INTS6	INTS12	0.954	0.48	hein_WMM bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM
INTS6	INTS2	0.954	0.414	hein_WMM bioplex_WMM bioplex3_WMM WMM_only
INTS12	INTS9	0.936	0.564	hein_WMM youn_WMM WMM_only
INTS11	INTS2	0.891	0.124	hein_WMM bioplex_WMM bioplex3_WMM WMM_only
INTS12	INTS11	0.86	0.432	hein_WMM bioplex_WMM bioplex3_WMM WMM_only
INTS9	INTS2	0.809	0.272	hein_WMM bioplex3_WMM youn_WMM WMM_only
FOXC1	INTS3	0.775	0.072	hein_WMM bioplex3_WMM youn_WMM WMM_only
FOXC1	INTS9	0.763	0.04	hein_WMM youn_WMM WMM_only
FOXC1	INTS4	0.737	0.086	hein_WMM bioplex3_WMM youn_WMM WMM_only
INTS1	INTS11	0.709	0.476	hein_WMM bioplex_WMM bioplex3_WMM WMM_only
INTS1	INTS9	0.688	0.394	hein_WMM youn_WMM WMM_only
FOXC1	INTS2	0.655	0.08	hein_WMM bioplex3_WMM youn_WMM WMM_only
INTS3	INTS9	0.311	0.268	hein_WMM bioplex3_WMM youn_WMM gupta_WMM WMM_only
FOXC1	INTS11	0.282	0.046	hein_WMM bioplex3_WMM WMM_only

Related Complexes

Genename	Complexes
INTS11	huMAP3_06382.1 huMAP3_06989.1 huMAP3_08278.1 huMAP3_09230.1 huMAP3_10641.1 huMAP3_12564.1 huMAP3_15286.1
INTS6	huMAP3_01810.1 huMAP3_04137.1 huMAP3_04823.1 huMAP3_06989.1 huMAP3_08147.1 huMAP3_08278.1 huMAP3_08985.1 huMAP3_09230.1 huMAP3_09363.1 huMAP3_10641.1 huMAP3_10684.1 huMAP3_12564.1 huMAP3_13510.1 huMAP3_15286.1
INTS3	huMAP3_01810.1 huMAP3_02054.1 huMAP3_07468.1 huMAP3_07627.1 huMAP3_07821.1 huMAP3_08147.1 huMAP3_08870.1 huMAP3_09230.1 huMAP3_09666.1 huMAP3_10202.1 huMAP3_10287.1 huMAP3_10641.1 huMAP3_10684.1 huMAP3_11232.1 huMAP3_13648.1 huMAP3_14291.1
INTS9	huMAP3_05510.1 huMAP3_08985.1 huMAP3_09230.1 huMAP3_09363.1 huMAP3_10641.1 huMAP3_12564.1 huMAP3_13510.1 huMAP3_15286.1
INTS4	huMAP3_06382.1 huMAP3_06914.1 huMAP3_06989.1 huMAP3_08278.1 huMAP3_08985.1 huMAP3_09230.1 huMAP3_09363.1 huMAP3_10641.1 huMAP3_12564.1 huMAP3_13510.1 huMAP3_15286.1
INTS2	huMAP3_06382.1 huMAP3_09230.1 huMAP3_10641.1 huMAP3_11232.1 huMAP3_12564.1
FOXC1	huMAP3_00847.1 huMAP3_04823.1 huMAP3_06695.1 huMAP3_06989.1 huMAP3_07998.1 huMAP3_08278.1 huMAP3_09230.1 huMAP3_09709.1 huMAP3_10333.1 huMAP3_10641.1 huMAP3_13510.1
INTS1	huMAP3_04823.1 huMAP3_06382.1 huMAP3_06989.1 huMAP3_08278.1 huMAP3_09230.1 huMAP3_09363.1 huMAP3_10641.1
INTS12	huMAP3_04823.1 huMAP3_06382.1 huMAP3_06914.1 huMAP3_06989.1 huMAP3_08278.1 huMAP3_09230.1 huMAP3_09363.1 huMAP3_10153.1 huMAP3_10641.1 huMAP3_12564.1 huMAP3_15286.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_09230.1