hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09239.1
Complex Portal: CPX-23044
Confidence: Moderate High
Proteins| Genename | Protein Name | Uniprot Annotation Score | Links |
|---|---|---|---|
| TGM5 | Protein-glutamine gamma-glutamyltransferase 5 (EC 2.3.2.13) (Transglutaminase X) (TG(X)) (TGX) (TGase X) (Transglutaminase-5) (TGase-5) | 5 | UniProt NCBI |
| KLK5 | Kallikrein-5 (EC 3.4.21.-) (Kallikrein-like protein 2) (KLK-L2) (Stratum corneum tryptic enzyme) | 5 | UniProt NCBI |
| FABP5 | Fatty acid-binding protein 5 (Epidermal-type fatty acid-binding protein) (E-FABP) (Fatty acid-binding protein, epidermal) (Psoriasis-associated fatty acid-binding protein homolog) (PA-FABP) | 5 | UniProt NCBI |
| ALDH3A1 | Aldehyde dehydrogenase, dimeric NADP-preferring (EC 1.2.1.5) (ALDHIII) (Aldehyde dehydrogenase 3) (Aldehyde dehydrogenase family 3 member A1) | 5 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| HPA:0461402 | 0.00620298148036 | 0.5 | FABP5 KLK5 | skin 1; cells in corneal layer[>=Medium] |
| HPA:0461401 | 0.0136651670059 | 0.5 | FABP5 KLK5 | skin 1; cells in corneal layer[>=Low] |
| REAC:R-HSA-6809371 | 0.022534212454 | 0.5 | TGM5 KLK5 | Formation of the cornified envelope |
| REAC:R-HSA-6805567 | 0.0239057396727 | 0.5 | TGM5 KLK5 | Keratinization |
| HPA:0471401 | 0.0328453637696 | 0.5 | FABP5 KLK5 | skin 2; cells in corneal layer[>=Low] |
Edges
| Protein 1 | Protein 2 | Score | ProteomeHD | Interface Overlap | Evidence |
|---|---|---|---|---|---|
| ALDH3A1 | KLK5 | 0.986 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| ALDH3A1 | FABP5 | 0.985 | 0.088 | bioplex3_HEK293 bioplex () bioplex_WMM bioplex3_WMM | |
| TGM5 | ALDH3A1 | 0.983 | bioplex3_WMM bioplex3_HCT116 WMM_only | ||
| TGM5 | KLK5 | 0.802 | bioplex_WMM bioplex3_WMM WMM_only | ||
| TGM5 | FABP5 | 0.49 | bioplex_WMM bioplex3_WMM WMM_only | ||
| KLK5 | FABP5 | 0.274 | bioplex_WMM bioplex3_WMM WMM_only boldt_WMM |
Related Complexes