hu.MAP 3.0: Complex View

Human Protein Complex Map

Complex: huMAP3_09242.1

Confidence: Moderate High

Genename	Protein Name	Uniprot Annotation Score	Links
VDR	Vitamin D3 receptor (VDR) (1,25-dihydroxyvitamin D3 receptor) (Nuclear receptor subfamily 1 group I member 1)	5	UniProt NCBI
ATP6V1F	V-type proton ATPase subunit F (V-ATPase subunit F) (V-ATPase 14 kDa subunit) (Vacuolar proton pump subunit F)	5	UniProt NCBI
ATP6V1B2	V-type proton ATPase subunit B, brain isoform (V-ATPase subunit B 2) (Endomembrane proton pump 58 kDa subunit) (HO57) (Vacuolar proton pump subunit B 2)	5	UniProt NCBI
ATP6V1E2	V-type proton ATPase subunit E 2 (V-ATPase subunit E 2) (Vacuolar proton pump subunit E 2)	4	UniProt NCBI
ATP6V1G3	V-type proton ATPase subunit G 3 (V-ATPase subunit G 3) (V-ATPase 13 kDa subunit 3) (Vacuolar proton pump subunit G 3)	4	UniProt NCBI
ATP6V1G1	V-type proton ATPase subunit G 1 (V-ATPase subunit G 1) (V-ATPase 13 kDa subunit 1) (Vacuolar proton pump subunit G 1) (Vacuolar proton pump subunit M16)	5	UniProt NCBI
TLDC2	TLD domain-containing protein 2 (TBC/LysM-associated domain-containing protein 2)	2	UniProt NCBI
ATP6V1D	V-type proton ATPase subunit D (V-ATPase subunit D) (V-ATPase 28 kDa accessory protein) (Vacuolar proton pump subunit D)	5	UniProt NCBI
RAPGEF3	Rap guanine nucleotide exchange factor 3 (Exchange factor directly activated by cAMP 1) (Exchange protein directly activated by cAMP 1) (EPAC 1) (Rap1 guanine-nucleotide-exchange factor directly activated by cAMP) (cAMP-regulated guanine nucleotide exchange factor I) (cAMP-GEFI)	5	UniProt NCBI
ATP6V1B1	V-type proton ATPase subunit B, kidney isoform (V-ATPase subunit B 1) (Endomembrane proton pump 58 kDa subunit) (Vacuolar proton pump subunit B 1)	5	UniProt NCBI
ATP6V1E1	V-type proton ATPase subunit E 1 (V-ATPase subunit E 1) (V-ATPase 31 kDa subunit) (p31) (Vacuolar proton pump subunit E 1)	5	UniProt NCBI
ROGDI	Protein rogdi homolog	5	UniProt NCBI
DMXL1	DmX-like protein 1 (X-like 1 protein)	3	UniProt NCBI
ATP6V1C1	V-type proton ATPase subunit C 1 (V-ATPase subunit C 1) (Vacuolar proton pump subunit C 1)	5	UniProt NCBI
WDR7	WD repeat-containing protein 7 (Rabconnectin-3 beta) (TGF-beta resistance-associated protein TRAG)	3	UniProt NCBI
NCOA7	Nuclear receptor coactivator 7 (140 kDa estrogen receptor-associated protein) (Estrogen nuclear receptor coactivator 1)	5	UniProt NCBI
TBC1D24	TBC1 domain family member 24	5	UniProt NCBI
ATP6V1G2	V-type proton ATPase subunit G 2 (V-ATPase subunit G 2) (V-ATPase 13 kDa subunit 2) (Vacuolar proton pump subunit G 2)	5	UniProt NCBI
ATP6V1A	V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (V-ATPase 69 kDa subunit) (Vacuolar ATPase isoform VA68) (Vacuolar proton pump subunit alpha)	5	UniProt NCBI
ATP6V1C2	V-type proton ATPase subunit C 2 (V-ATPase subunit C 2) (Vacuolar proton pump subunit C 2)	5	UniProt NCBI

Enrichments

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
KEGG:04966	1.55245833863e-26	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Collecting duct acid secretion
REAC:R-HSA-917977	1.29087324241e-24	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Transferrin endocytosis and recycling
REAC:R-HSA-77387	1.29087324241e-24	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Insulin receptor recycling
REAC:R-HSA-1222556	5.08317708485e-24	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	ROS and RNS production in phagocytes
KEGG:05110	1.15426390002e-22	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Vibrio cholerae infection
GO:0000221	1.59701662709e-21	0.5	ATP6V1E1 ATP6V1B2 ATP6V1G1 ATP6V1A ATP6V1C1 ATP6V1F ATP6V1C2 ATP6V1D ATP6V1G2	vacuolar proton-transporting V-type ATPase, V1 domain
GO:0033180	1.59701662709e-21	0.5	ATP6V1E1 ATP6V1B2 ATP6V1G1 ATP6V1A ATP6V1C1 ATP6V1F ATP6V1C2 ATP6V1D ATP6V1G2	proton-transporting V-type ATPase, V1 domain
REAC:R-HSA-917937	3.59287599009e-21	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Iron uptake and transport
KEGG:04721	3.87130906674e-21	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Synaptic vesicle cycle
REAC:R-HSA-9639288	4.53187031963e-21	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Amino acids regulate mTORC1
KEGG:05120	6.94707655251e-21	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Epithelial cell signaling in Helicobacter pylori infection
GO:0016471	1.15135636944e-20	0.555555555556	ATP6V1E1 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1B2 ATP6V1C2 ATP6V1D ATP6V1G3	vacuolar proton-transporting V-type ATPase complex
KEGG:05323	1.72572046845e-20	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Rheumatoid arthritis
GO:0033176	2.03600004624e-20	0.555555555556	ATP6V1E1 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1B2 ATP6V1C2 ATP6V1D ATP6V1G3	proton-transporting V-type ATPase complex
REAC:R-HSA-74752	3.00995663121e-20	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Signaling by Insulin receptor
GO:0033178	7.0353525665e-19	0.5	ATP6V1E1 ATP6V1B2 ATP6V1G1 ATP6V1A ATP6V1C1 ATP6V1F ATP6V1C2 ATP6V1D ATP6V1G2	proton-transporting two-sector ATPase complex, catalytic domain
KEGG:00190	1.54239657231e-17	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Oxidative phosphorylation
KEGG:04145	3.78734472028e-17	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Phagosome
GO:0016469	4.36968016435e-17	0.555555555556	ATP6V1E1 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1B2 ATP6V1C2 ATP6V1D ATP6V1G3	proton-transporting two-sector ATPase complex
REAC:R-HSA-983712	9.74419563623e-17	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Ion channel transport
KEGG:04150	1.38811656346e-16	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	mTOR signaling pathway
REAC:R-HSA-9711097	1.06078559894e-15	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Cellular response to starvation
GO:0042625	4.45124505529e-14	0.388888888889	ATP6V1E1 ATP6V1B2 ATP6V1C2 ATP6V1A ATP6V1C1 ATP6V1F ATP6V1E2	ATPase-coupled ion transmembrane transporter activity
KEGG:05165	2.99410597133e-13	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Human papillomavirus infection
GO:1904949	8.94538433473e-12	0.555555555556	ATP6V1E1 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1B2 ATP6V1C2 ATP6V1D ATP6V1G3	ATPase complex
GO:0044769	3.16038047507e-11	0.333333333333	ATP6V1E1 ATP6V1B2 ATP6V1C2 ATP6V1A ATP6V1C1 ATP6V1E2	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
GO:0046961	3.16038047507e-11	0.333333333333	ATP6V1E1 ATP6V1B2 ATP6V1C2 ATP6V1A ATP6V1C1 ATP6V1E2	proton-transporting ATPase activity, rotational mechanism
REAC:R-HSA-9006934	1.08205516126e-10	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Signaling by Receptor Tyrosine Kinases
WP:WP4917	5.17311473209e-10	0.333333333333	ATP6V1E1 ATP6V1F ATP6V1G1 ATP6V1A ATP6V1C1 ATP6V1D	Proximal tubule transport
GO:0016241	7.90977852173e-10	0.5	ATP6V1E1 ATP6V1G2 ATP6V1G1 ATP6V1A ATP6V1C1 ATP6V1B2 ATP6V1C2 ATP6V1D ATP6V1E2	regulation of macroautophagy
REAC:R-HSA-382551	1.06837394299e-09	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Transport of small molecules
REAC:R-HSA-2262752	2.88072298621e-08	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Cellular responses to stress
REAC:R-HSA-8953897	3.19488838181e-08	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Cellular responses to stimuli
GO:0042626	6.48430813866e-08	0.388888888889	ATP6V1E1 ATP6V1B2 ATP6V1C2 ATP6V1A ATP6V1C1 ATP6V1F ATP6V1E2	ATPase-coupled transmembrane transporter activity
GO:0005774	1.06671405156e-07	0.555555555556	ATP6V1E1 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1B2 ATP6V1C2 ATP6V1D ATP6V1G3	vacuolar membrane
GO:0019829	1.56142390646e-07	0.333333333333	ATP6V1E1 ATP6V1B2 ATP6V1C2 ATP6V1A ATP6V1C1 ATP6V1E2	ATPase-coupled monoatomic cation transmembrane transporter activity
REAC:R-HSA-168249	2.59806296439e-07	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Innate Immune System
GO:0015078	4.67021511839e-07	0.388888888889	ATP6V1E1 ATP6V1B2 ATP6V1C2 ATP6V1A ATP6V1C1 ATP6V1F ATP6V1E2	proton transmembrane transporter activity
GO:0016236	5.09538993817e-07	0.5	ATP6V1E1 ATP6V1G2 ATP6V1G1 ATP6V1A ATP6V1C1 ATP6V1B2 ATP6V1C2 ATP6V1D ATP6V1E2	macroautophagy
GO:0010506	9.60766101771e-07	0.5	ATP6V1E1 ATP6V1G2 ATP6V1G1 ATP6V1A ATP6V1C1 ATP6V1B2 ATP6V1C2 ATP6V1D ATP6V1E2	regulation of autophagy
GO:1902600	1.9224979353e-06	0.333333333333	ATP6V1E1 ATP6V1B2 ATP6V1F ATP6V1A ATP6V1C1 ATP6V1D	proton transmembrane transport
KEGG:01100	2.68913812846e-06	0.611111111111	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Metabolic pathways
GO:0015399	4.92036650327e-06	0.388888888889	ATP6V1E1 ATP6V1B2 ATP6V1C2 ATP6V1A ATP6V1C1 ATP6V1F ATP6V1E2	primary active transmembrane transporter activity
GO:0007035	7.45394968083e-06	0.277777777778	ATP6V1D DMXL1 ATP6V1A ATP6V1F ATP6V1B2	vacuolar acidification
REAC:R-HSA-168256	1.58393382795e-05	0.666666666667	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 RAPGEF3 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Immune System
GO:0005773	3.35516537043e-05	0.555555555556	ATP6V1E1 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1B2 ATP6V1C2 ATP6V1D ATP6V1G3	vacuole
GO:0006914	4.11517839582e-05	0.5	ATP6V1E1 ATP6V1G2 ATP6V1G1 ATP6V1A ATP6V1C1 ATP6V1B2 ATP6V1C2 ATP6V1D ATP6V1E2	autophagy
GO:0061919	4.11517839582e-05	0.5	ATP6V1E1 ATP6V1G2 ATP6V1G1 ATP6V1A ATP6V1C1 ATP6V1B2 ATP6V1C2 ATP6V1D ATP6V1E2	process utilizing autophagic mechanism
GO:0051452	5.62913092884e-05	0.277777777778	ATP6V1D DMXL1 ATP6V1A ATP6V1F ATP6V1B2	intracellular pH reduction
GO:0098852	0.000101350371569	0.444444444444	ATP6V1E1 ATP6V1B2 ATP6V1G1 ATP6V1A ATP6V1C1 ATP6V1F ATP6V1C2 ATP6V1D	lytic vacuole membrane
GO:0005765	0.000101350371569	0.444444444444	ATP6V1E1 ATP6V1B2 ATP6V1G1 ATP6V1A ATP6V1C1 ATP6V1F ATP6V1C2 ATP6V1D	lysosomal membrane
REAC:R-HSA-162582	0.000122791188251	0.666666666667	ATP6V1E1 ATP6V1B2 ATP6V1C1 ATP6V1G1 ATP6V1G2 RAPGEF3 ATP6V1F ATP6V1A ATP6V1G3 ATP6V1C2 ATP6V1D ATP6V1E2	Signal Transduction
HP:0006891	0.000159953050463	0.166666666667	ATP6V1E1 ATP6V1A TBC1D24	Thick cerebral cortex
GO:0031329	0.000213390332497	0.5	ATP6V1E1 ATP6V1G2 ATP6V1G1 ATP6V1A ATP6V1C1 ATP6V1B2 ATP6V1C2 ATP6V1D ATP6V1E2	regulation of cellular catabolic process
GO:0051453	0.000404492589144	0.277777777778	ATP6V1D DMXL1 ATP6V1A ATP6V1F ATP6V1B2	regulation of intracellular pH
GO:0030641	0.000478545872576	0.277777777778	ATP6V1D DMXL1 ATP6V1A ATP6V1F ATP6V1B2	regulation of cellular pH
GO:0006885	0.000609477468338	0.277777777778	ATP6V1D DMXL1 ATP6V1A ATP6V1F ATP6V1B2	regulation of pH
GO:0022853	0.000922536747393	0.333333333333	ATP6V1E1 ATP6V1B2 ATP6V1C2 ATP6V1A ATP6V1C1 ATP6V1E2	active monoatomic ion transmembrane transporter activity
GO:0022804	0.00100581295679	0.388888888889	ATP6V1E1 ATP6V1B2 ATP6V1C2 ATP6V1A ATP6V1C1 ATP6V1F ATP6V1E2	active transmembrane transporter activity
GO:0098796	0.00132189239499	0.555555555556	ATP6V1E1 ATP6V1C1 ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1A ATP6V1B2 ATP6V1C2 ATP6V1D ATP6V1G3	membrane protein complex
HP:0031423	0.00174718805299	0.111111111111	TBC1D24 ATP6V1B2	Small cerebellar cortex
GO:0022890	0.00442579250267	0.388888888889	ATP6V1E1 ATP6V1B2 ATP6V1C2 ATP6V1A ATP6V1C1 ATP6V1F ATP6V1E2	inorganic cation transmembrane transporter activity
CORUM:6888	0.00521120958248	0.111111111111	ATP6V1B2 ATP6V1A	v-ATPase-Ragulator-AXIN/LKB1-AMPK complex
HP:0025244	0.00523773811247	0.111111111111	ATP6V1E1 ATP6V1A	Subretinal pigment epithelium hemorrhage
HP:0031282	0.00523773811247	0.111111111111	TBC1D24 ATP6V1B2	Malalignment of the great toenail
HP:0010324	0.00523773811247	0.111111111111	TBC1D24 ATP6V1B2	Abnormal morphology of phalanx of the 2nd toe
HP:0010347	0.00523773811247	0.111111111111	TBC1D24 ATP6V1B2	Aplasia/Hypoplasia of the phalanges of the 2nd toe
GO:0009894	0.00551559554994	0.5	ATP6V1E1 ATP6V1G2 ATP6V1G1 ATP6V1A ATP6V1C1 ATP6V1B2 ATP6V1C2 ATP6V1D ATP6V1E2	regulation of catabolic process
GO:0008324	0.00787976746892	0.388888888889	ATP6V1E1 ATP6V1B2 ATP6V1C2 ATP6V1A ATP6V1C1 ATP6V1F ATP6V1E2	monoatomic cation transmembrane transporter activity
GO:0005764	0.00821703212229	0.444444444444	ATP6V1E1 ATP6V1B2 ATP6V1G1 ATP6V1A ATP6V1C1 ATP6V1F ATP6V1C2 ATP6V1D	lysosome
GO:0000323	0.00821703212229	0.444444444444	ATP6V1E1 ATP6V1B2 ATP6V1G1 ATP6V1A ATP6V1C1 ATP6V1F ATP6V1C2 ATP6V1D	lytic vacuole
GO:0061795	0.00936146543831	0.166666666667	ATP6V1D ATP6V1F ATP6V1A	Golgi lumen acidification
GO:0048388	0.00936146543831	0.166666666667	ATP6V1D ATP6V1F ATP6V1A	endosomal lumen acidification
HP:0011326	0.0104678300234	0.111111111111	TBC1D24 ATP6V1B2	Anterior plagiocephaly
HP:0007457	0.0104678300234	0.111111111111	ATP6V1E1 ATP6V1A	Prominent veins on trunk
HPA:0271153	0.0116693617604	0.166666666667	ATP6V1D ATP6V1F ATP6V1B2	kidney; proximal tubules (microvilli)[High]
GO:0140657	0.0143201798442	0.388888888889	ATP6V1E1 ATP6V1B2 ATP6V1C2 ATP6V1A ATP6V1C1 ATP6V1F ATP6V1E2	ATP-dependent activity
GO:0015318	0.0158251343343	0.388888888889	ATP6V1E1 ATP6V1B2 ATP6V1C2 ATP6V1A ATP6V1C1 ATP6V1F ATP6V1E2	inorganic molecular entity transmembrane transporter activity
HP:0001305	0.0173432407296	0.222222222222	ATP6V1E1 ATP6V1A ATP6V1B2 TBC1D24	Dandy-Walker malformation
HP:0031422	0.0174336495146	0.111111111111	TBC1D24 ATP6V1B2	Abnormal cerebellar cortex morphology
HPA:0100212	0.0197499645214	0.555555555556	DMXL1 ATP6V1B2 ATP6V1E1 ATP6V1C1 RAPGEF3 ATP6V1F NCOA7 WDR7 ATP6V1D ATP6V1G2	cerebral cortex; neuropil[>=Medium]
KEGG:04142	0.0254587997657	0.166666666667	DMXL1 NCOA7 WDR7	Lysosome
HP:0000455	0.0256249480333	0.222222222222	ATP6V1E1 ATP6V1A ATP6V1B2 TBC1D24	Broad nasal tip
GO:0015075	0.025908820806	0.388888888889	ATP6V1E1 ATP6V1B2 ATP6V1C2 ATP6V1A ATP6V1C1 ATP6V1F ATP6V1E2	monoatomic ion transmembrane transporter activity
HP:0025082	0.0261313881914	0.111111111111	ATP6V1E1 ATP6V1A	Abnormal cutaneous elastic fiber morphology
HP:0025167	0.0261313881914	0.111111111111	ATP6V1E1 ATP6V1A	Fragmented elastic fibers in the dermis
HP:0010950	0.0302964509173	0.222222222222	ATP6V1E1 ATP6V1A ATP6V1B2 TBC1D24	Abnormal fourth ventricle morphology
HP:0002198	0.0302964509173	0.222222222222	ATP6V1E1 ATP6V1A ATP6V1B2 TBC1D24	Dilated fourth ventricle
HPA:0090971	0.033441670554	0.222222222222	ATP6V1G1 ATP6V1G2 ATP6V1F ATP6V1B2	cerebellum; granular cells - cytoplasm/membrane[>=Low]
HP:0002350	0.0346443948738	0.222222222222	ATP6V1E1 ATP6V1A ATP6V1B2 TBC1D24	Cerebellar cyst
HP:0007552	0.0365572435281	0.111111111111	ATP6V1E1 ATP6V1A	Abnormal subcutaneous fat tissue distribution
HP:0025201	0.0487074188602	0.111111111111	ATP6V1E1 ATP6V1A	Abnormal circulating apolipoprotein concentration
HP:0009933	0.0487074188602	0.111111111111	ATP6V1E1 ATP6V1A	Narrow naris

Edges

Protein 1	Protein 2	Score	ProteomeHD
ATP6V1F	ATP6V1B2	1.0	0.462
ATP6V1B2	ATP6V1A	1.0	0.832
ATP6V1B2	ATP6V1D	1.0	0.65
ATP6V1D	ATP6V1E1	1.0	0.792
ATP6V1E2	ATP6V1C2	1.0
ATP6V1F	ATP6V1C2	1.0
ATP6V1B2	ATP6V1E1	1.0	0.93
ATP6V1D	ATP6V1A	1.0	0.548
ATP6V1B1	ATP6V1D	1.0
ATP6V1F	ATP6V1B1	1.0
ATP6V1E2	ATP6V1B1	1.0
ATP6V1B1	ATP6V1G1	1.0
ATP6V1C2	ATP6V1A	1.0
WDR7	ROGDI	1.0
ATP6V1D	ATP6V1C2	1.0
ATP6V1E1	ATP6V1A	0.999	0.816
DMXL1	ROGDI	0.999	0.11
ATP6V1E1	ATP6V1C2	0.999
ATP6V1G2	ATP6V1E2	0.999
ATP6V1E2	ATP6V1G1	0.999
ATP6V1B1	ATP6V1E1	0.999
ATP6V1C1	ATP6V1B1	0.999
ATP6V1B2	ATP6V1B1	0.999
ATP6V1G2	ATP6V1C2	0.999
ATP6V1C2	ATP6V1G1	0.999
ATP6V1E2	ATP6V1D	0.999
ATP6V1B2	ATP6V1E2	0.999
ATP6V1B2	ATP6V1C2	0.999
ATP6V1C1	ATP6V1B2	0.999	0.304
ATP6V1B1	ATP6V1A	0.999
ATP6V1E1	ATP6V1G1	0.999	0.92
ATP6V1C1	ATP6V1D	0.999	0.188
ATP6V1D	ATP6V1G1	0.999	0.7
ATP6V1F	ATP6V1G2	0.999	0.062
ATP6V1F	ATP6V1D	0.999	0.924
ATP6V1F	ATP6V1G1	0.999	0.746
ATP6V1C1	ATP6V1C2	0.999
ATP6V1G2	ATP6V1D	0.999	0.136
ATP6V1C1	ATP6V1G1	0.998	0.344
ATP6V1C1	ATP6V1G2	0.998	0.058
ATP6V1F	ATP6V1E1	0.998	0.618
WDR7	ATP6V1B1	0.998
ATP6V1B2	ATP6V1G1	0.998	0.79
ATP6V1G1	ATP6V1A	0.998	0.844
NCOA7	ATP6V1B1	0.998
ATP6V1F	ATP6V1A	0.998	0.606
WDR7	ATP6V1G2	0.997
DMXL1	ATP6V1B1	0.997
ATP6V1G2	ATP6V1A	0.997	0.206
ATP6V1G2	ATP6V1E1	0.997	0.118666666667
DMXL1	ATP6V1G1	0.997	0.056
ATP6V1G2	ATP6V1B2	0.997	0.156
NCOA7	ATP6V1B2	0.996	0.074
NCOA7	ATP6V1G1	0.996	0.054
TBC1D24	ATP6V1G1	0.996	0.03
TBC1D24	ATP6V1B2	0.994	0.078
ATP6V1G2	ATP6V1G1	0.994	0.06
NCOA7	ATP6V1D	0.993	0.024
ATP6V1F	ATP6V1C1	0.993	0.196
DMXL1	ATP6V1G2	0.992	0.0743333333333
TBC1D24	ATP6V1D	0.992	0.052
ATP6V1C1	ATP6V1A	0.991	0.29
DMXL1	ATP6V1B2	0.991	0.078
ATP6V1G2	ATP6V1B1	0.99
ATP6V1B2	ROGDI	0.989	0.124
ATP6V1B1	ATP6V1C2	0.988
TBC1D24	ATP6V1B1	0.987
ATP6V1C1	ATP6V1E1	0.987	0.23
ATP6V1G2	VDR	0.986
ATP6V1B2	RAPGEF3	0.984	0.17
ATP6V1C1	ATP6V1E2	0.982
WDR7	ATP6V1B2	0.98
TLDC2	ATP6V1A	0.98
WDR7	DMXL1	0.978
ATP6V1F	ATP6V1E2	0.978
ATP6V1E2	ATP6V1A	0.978
ATP6V1E2	ATP6V1E1	0.978
WDR7	ATP6V1G1	0.977
DMXL1	ATP6V1C2	0.975
ATP6V1G3	ATP6V1A	0.974
NCOA7	ATP6V1G2	0.972	0.072
NCOA7	ATP6V1E2	0.969
NCOA7	DMXL1	0.964	0.06
WDR7	NCOA7	0.964
NCOA7	ATP6V1C1	0.964	0.078
NCOA7	ATP6V1C2	0.964
ATP6V1D	TLDC2	0.96
NCOA7	ATP6V1A	0.959	0.106
DMXL1	ATP6V1E2	0.958
ATP6V1C1	TLDC2	0.957
WDR7	ATP6V1E2	0.957
ATP6V1B2	ATP6V1G3	0.955
WDR7	ATP6V1C2	0.952
ATP6V1F	NCOA7	0.952	0.028
ATP6V1B2	TLDC2	0.95
WDR7	ATP6V1C1	0.946
ATP6V1F	DMXL1	0.946	0.032
DMXL1	ATP6V1C1	0.946	0.108
DMXL1	ATP6V1E1	0.946	0.044
DMXL1	ATP6V1D	0.946	0.064
DMXL1	ATP6V1A	0.946	0.076
NCOA7	ATP6V1E1	0.936	0.052
WDR7	ATP6V1D	0.933
WDR7	ATP6V1E1	0.933
ATP6V1F	WDR7	0.931
ATP6V1E1	TLDC2	0.922
ATP6V1G1	TLDC2	0.92
WDR7	ATP6V1A	0.912
TBC1D24	ATP6V1G2	0.811	0.078
TBC1D24	DMXL1	0.799	0.022
TBC1D24	WDR7	0.799
ATP6V1F	TLDC2	0.789
TBC1D24	ATP6V1A	0.674	0.13
TBC1D24	NCOA7	0.672	0.058
TBC1D24	ATP6V1E2	0.672
TBC1D24	ATP6V1E1	0.654	0.046
TBC1D24	ATP6V1C1	0.654	0.11
TBC1D24	ATP6V1C2	0.646
ATP6V1F	TBC1D24	0.618	0.086
ATP6V1E1	ATP6V1G3	0.605
ATP6V1B1	ROGDI	0.415
NCOA7	RAPGEF3	0.415	0.072
ATP6V1B1	RAPGEF3	0.415
RAPGEF3	ROGDI	0.415	0.066
WDR7	RAPGEF3	0.415
ATP6V1E2	RAPGEF3	0.415
DMXL1	RAPGEF3	0.415	0.082
RAPGEF3	ATP6V1A	0.385	0.095
RAPGEF3	ATP6V1G1	0.297	0.102
ATP6V1C2	RAPGEF3	0.278
ATP6V1G2	RAPGEF3	0.278
NCOA7	ROGDI	0.274	0.056
ATP6V1E2	ROGDI	0.274
ATP6V1C1	RAPGEF3	0.274	0.094
ATP6V1E1	RAPGEF3	0.254	0.06
ATP6V1D	RAPGEF3	0.21	0.144
ATP6V1C1	ROGDI	0.113	0.076
ATP6V1C2	ROGDI	0.113
ATP6V1E1	ROGDI	0.113	0.056
TBC1D24	RAPGEF3	0.113	0.042
ATP6V1F	RAPGEF3	0.093	0.06
ATP6V1F	ROGDI	0.089	0.066
ATP6V1D	ROGDI	0.078	0.042
TBC1D24	ROGDI	0.076	0.11
ATP6V1G2	ROGDI	0.074	0.116
ROGDI	ATP6V1A	0.035	0.094
ROGDI	ATP6V1G1	0.029	0.07
VDR	ATP6V1A	0.009

Related Complexes

Genename	Complexes
VDR	huMAP3_04524.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_11200.1 huMAP3_13750.1 huMAP3_13789.1
ATP6V1F	huMAP3_00308.1 huMAP3_01501.1 huMAP3_05444.1 huMAP3_05805.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1B2	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_05805.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1E2	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1G3	huMAP3_05070.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1G1	huMAP3_01501.1 huMAP3_05805.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
TLDC2	huMAP3_05070.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1D	huMAP3_01413.1 huMAP3_05805.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
RAPGEF3	huMAP3_01501.1 huMAP3_01899.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1B1	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_05805.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1E1	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_05805.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
ROGDI	huMAP3_01501.1 huMAP3_01899.1 huMAP3_03469.1 huMAP3_05952.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_12042.1 huMAP3_13872.1
DMXL1	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_03469.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1C1	huMAP3_01413.1 huMAP3_05070.1 huMAP3_05805.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
WDR7	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_03469.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
NCOA7	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
TBC1D24	huMAP3_00552.1 huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13467.1 huMAP3_13872.1
ATP6V1G2	huMAP3_01413.1 huMAP3_04524.1 huMAP3_05805.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1A	huMAP3_05070.1 huMAP3_05805.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_13872.1
ATP6V1C2	huMAP3_01413.1 huMAP3_01501.1 huMAP3_01899.1 huMAP3_07099.1 huMAP3_07329.1 huMAP3_08381.1 huMAP3_08678.1 huMAP3_09242.1 huMAP3_09477.1 huMAP3_09873.1 huMAP3_10511.1 huMAP3_10516.1 huMAP3_12042.1 huMAP3_12827.1 huMAP3_13872.1

hu.MAP 3.0: Complex View

Search for a protein

Complex: huMAP3_09242.1