hu.MAP 3.0: Complex View
Human Protein Complex Map
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Complex: huMAP3_09249.1
Confidence: Moderate High  
ProteinsGenename | Protein Name | Uniprot Annotation Score | Links |
---|---|---|---|
ACVR2B | Activin receptor type-2B (EC 2.7.11.30) (Activin receptor type IIB) (ACTR-IIB) | 5 | UniProt   NCBI |
BMPR1A | Bone morphogenetic protein receptor type-1A (BMP type-1A receptor) (BMPR-1A) (EC 2.7.11.30) (Activin receptor-like kinase 3) (ALK-3) (Serine/threonine-protein kinase receptor R5) (SKR5) (CD antigen CD292) | 5 | UniProt   NCBI |
PLEKHH3 | Pleckstrin homology domain-containing family H member 3 (PH domain-containing family H member 3) | 3 | UniProt   NCBI |
Enrichments
Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
---|---|---|---|---|
  REAC:R-HSA-201451 | 0.00204339075673 | 0.666666666667 | ACVR2B BMPR1A | Signaling by BMP |
  KEGG:04350 | 0.0028446957576 | 0.666666666667 | ACVR2B BMPR1A | TGF-beta signaling pathway |
  KEGG:05418 | 0.00515305589505 | 0.666666666667 | ACVR2B BMPR1A | Fluid shear stress and atherosclerosis |
  KEGG:04550 | 0.00542112539104 | 0.666666666667 | ACVR2B BMPR1A | Signaling pathways regulating pluripotency of stem cells |
  WP:WP2857 | 0.00901139826353 | 0.666666666667 | ACVR2B BMPR1A | Mesodermal commitment pathway |
  WP:WP5316 | 0.00929774738496 | 0.666666666667 | ACVR2B BMPR1A | Primary ovarian insufficiency |
  KEGG:04060 | 0.0146065267115 | 0.666666666667 | ACVR2B BMPR1A | Cytokine-cytokine receptor interaction |
  CORUM:3043 | 0.0249718442456 | 0.333333333333 | BMPR1A | BMP2-BRIA complex |
  REAC:R-HSA-9006936 | 0.0392065258044 | 0.666666666667 | ACVR2B BMPR1A | Signaling by TGFB family members |
Edges
Protein 1 | Protein 2 | Score | ProteomeHD | Evidence |
---|---|---|---|---|
 ACVR2B |  PLEKHH3 | 0.987 |            | bioplex3_HEK293     bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     WMM_only     |
 ACVR2B |  BMPR1A | 0.986 |            | bioplex_WMM     bioplex3_WMM     bioplex3_HCT116     WMM_only     |
 PLEKHH3 |  BMPR1A | 0.965 | 0.082           | bioplex_WMM     bioplex3_WMM     WMM_only     |
Related Complexes